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http://www.cure.med.ucla.edu/cores/human-studies
Core facility whose services include secretory tests, motility and pH tests, videoendoscopy, biopsy and histology, serum bank of patients with ulcer hemorrhage, and visceral sensitivity and autonomic function tests.
Proper citation: CURE - Digestive Diseases Research Center Human Studies Core (RRID:SCR_015207) Copy
Core facility whose services include histology, immunohistochemistry, RNA in situ hybridization, mRNA probe generation, frozen sections for enzyme histochemistry, immunofluorescent antibody studies, live and fixed cell confocal, deconvolution microscopy and super resolution microscopy (SIM and STORM), and transmission electron microscopy, quantitative morphometric analysis, high throughput microscopy and high content analysis, laser capture microdissection for molecular genetic analyses, and digital images for internet communication and publication.
Proper citation: Texas Medical Center Digestive Diseases Center Cellular and Molecular Morphology Core (RRID:SCR_015219) Copy
Core that provides epidemiological and biostatistical support for design and analysis, and also provides investigators with access to the clinical specimens required for their basic and translational research activities. It offers assistance as well as didactic training in issues involving local and foreign IRB?s, HIPPA regulations, and importing or exporting clinical specimens.
Proper citation: Texas Medical Center Digestive Diseases Center Study Design and Clinical Research Core Services (RRID:SCR_015218) Copy
https://www.bcm.edu/research/centers/digestive-disease/core-facilities/integrative-biology
Core that aims to provide turnkey access to organoids/enteroid technologies to TMC-DDC researchers. These include samples (enteroids, organoids), reagents (specialized growth media, etc.), training, and consultative expertise. The core also provides access to gnotobiotic facilities and animals, training and consultative expertise.
Proper citation: Texas Medical Center Digestive Diseases Center Integrative Biology Core (RRID:SCR_015220) Copy
http://cure.med.ucla.edu/cores/administrative
Management core that develops mission, goals, and strategies relating to the functioning of the CURE:DDRCC.
Proper citation: CURE - Digestive Diseases Research Center Administrative Core (RRID:SCR_015231) Copy
https://case.edu/medicine/cddrcc/cores/
Collection of four cores: the biorepository core, for clinical specimen storage; the Histology/Imaging Core, for tissue preparation and sectioning; the Mouse Models Core, for education and training on various mouse modeling techniques; and the Clinical Component of the Administrative Core, for clinical study design consultation.
Proper citation: Cleveland Digestive Diseases Research Core Facilities (RRID:SCR_015216) Copy
Core whose services include consultation in the choice of genomics methodologies to be applied to research problems being addressed by Digestive Diseases Center members, training in the conduct of functional genomics and metagenomics relevant to GI research, providing mammalian gene expression, cytokine/transcription factor/signaling pathway arrays, and gut microbial profiling/metagenomics to DDC members at discounted prices, and conducting periodic workshops and disseminating information about new technologies available in the Core and to obtain feedback on needed technologies / services.
Proper citation: Texas Medical Center Digestive Diseases Center Functional Genomics and Microbiome (RRID:SCR_015214) Copy
https://ddrcc.wustl.edu/scientific-cores/murine-models-gnotobiotics-core/
Core facility that provides advice and technical services to DDRCC investigators that include production of transgenic and chimeric mice, derivation of speed congenics and assisted reproduction services for maintaining pedigrees via the Mouse Genetics Core, as well as gnotobiotic mouse provision, colonization and rederivation.
Proper citation: Washington University Digestive Diseases Research Core Center Murine Models and Gnotobiotics Core (RRID:SCR_015260) Copy
https://ww2.mc.vanderbilt.edu/DDRC/19909
Core facility whose services include training, acquisition and analysis on cytometers for experiments that include different fluorochromes, imaging cytometry, and mass cytometry.
Proper citation: Vanderbilt Digestive Disease Research Center Flow Cytometry Core (RRID:SCR_015251) Copy
https://ww2.mc.vanderbilt.edu/DDRC/6914
Core facility whose goals include furnishing professional guidance in experimental design and data interpretation and providing access to optical and electron microscopy. Its services include confocal microscopy, wide-field microscopy, transmission electron microscopy, and processing and embedment of tissue or cells for EM.
Proper citation: Vanderbilt Digestive Disease Research Center Cellular Imaging Core (RRID:SCR_015250) Copy
https://hddc.hms.harvard.edu/core-b
Core facility that provides service for paraffin embedding, sectioning, staining, and frozen sectioning; shared equipment and service for confocal, widefield, photodocumentation, electron microscopy, and digital image processing; and an immunostaining service.
Proper citation: Harvard Digestive Diseases Center Biomedical CORE B: Microscopy and Histopathology (RRID:SCR_009836) Copy
https://hddc.hms.harvard.edu/gnotobiotics-microbiology-and-metagenomics
Core facility that assists investigators evaluating host microbiota and its role in normal physiology and disease. It includes a number of resources for groups studying the role of the microbiota in human health and disease.
Proper citation: Harvard Digestive Diseases Center Biomedical CORE D: Gnotobiotic Mice, Microbiology and Metagenomics (RRID:SCR_012319) Copy
http://www.uchicagoddrcc.org/research-cores/tissue-engineering-and-cell-models-core
Core that provides services such as a repository for intestinal cell lines, Tissue Engineering Models, experimental materials, and supplies for digestive disease research.
Proper citation: University of Chicago Digestive Diseases Research Core Center Tissue Engineering and Cell Models Core (RRID:SCR_015604) Copy
http://www.med.umich.edu/mgpc/
Center whose goal is to investigate signal transduction mechanisms regulating homeostasis and GI disorders. Their approach includes studies on genetics and gene regulation, cellular signaling pathways, receptors and ion channels.
Proper citation: University of Michigan Center for Gastrointestinal Research (RRID:SCR_015605) Copy
Communication network of current and potential biomedical research investigators and technical personnel from traditionally under-served communities: African American, Hispanic American, American Indian, Alaskan Native, Native Hawaiian, and other Pacific Islanders. The major objective of the network is to encourage and facilitate participation of members of underrepresented racial and ethnic minority groups in the conduct of biomedical research in the fields of diabetes, endocrinology, metabolism, digestive diseases, nutrition, kidney, urologic and hematologic diseases. A second objective is to encourage and enhance the potential of the underrepresented minority investigators in choosing a biomedical research career in these fields. An important component of this network is promotion of two-way communications between network members and the NIDDK.
Proper citation: Network of Minority Health Research Investigators (RRID:SCR_006589) Copy
https://ww2.mc.vanderbilt.edu/ddrc/
Center whose objectives include promoting digestive diseases-related research in an integrative, collaborative and multidisciplinary manner, developing and implementing programs for attracting, training, and retaining young investigators in digestive disease-related research, and facilitating the transfer of basic research discoveries to improvements in prevention and/or clinical care.
Proper citation: Vanderbilt Digestive Disease Research Center (RRID:SCR_015225) Copy
https://www.bcm.edu/research/centers/digestive-disease
Center designed to serve basic and clinical scientists at institutions within the Texas Medical Center, including Baylor College of Medicine, The University of Texas Health Science Center at Houston and the MD Anderson Cancer Center. It facilitates digestive diseases research, promotes translational collaborative research between basic and clinical areas, develops new projects, nurtures new investigators, and provides GI educational activities.
Proper citation: Texas Medical Center Digestive Diseases Center (RRID:SCR_015191) Copy
https://www.cincinnatichildrens.org/research/divisions/d/dhc
Center that is located within Cincinnati Children's Hospital Medical Center, that serves as a University of Cincinnati Academic Health Center resource to foster pediatric digestive disease research and make discoveries to restore digestive health.
Proper citation: Cincinnati Digestive Health Center (RRID:SCR_015196) Copy
https://www.niddk.nih.gov/research-funding/research-programs/digestive-disease-centers
Center of collaborating research centers working on the research of digestive and liver-related diseases. Each center focuses on etiology, treatment, and prevention of digestive and/or liver diseases.
Proper citation: Digestive Disease Centers (RRID:SCR_015212) Copy
https://case.edu/medicine/cddrcc/
Center that is focused on what produces the digestive diseases that affect millions of people in the U.S., such as inflammatory bowel disease, hepatitis, metabolic syndromes and obesity.
Proper citation: Cleveland Digestive Diseases Research Core Center (RRID:SCR_015210) Copy
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