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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Protein Subcellular Location Image Database Resource Report Resource Website |
Protein Subcellular Location Image Database (RRID:SCR_008663) | PSLID | storage service resource, data or information resource, image analysis service, database, service resource, data set, data repository |
THIS RESOURCE IS NO LONGER IN SERVICE. Documented August 23, 2017. Annotated database of fluorescence microscope images depicting subcellular location proteins with two interfaces: a text and image content search interface, and a graphical interface for exploring location patterns grouped into Subcellular Location Trees. The annotations in PSLID provide a description of sample preparation and fluorescence microscope imaging. |
protein, structure, subcellular, organelle, image, fluorescence microscope, annotation, classify, rank, cluster, subcellular localization, 3d spatial image, 2d spatial image, micrograph, content-based retrieval, green fluorescent protein |
is listed by: 3DVC is listed by: Biositemaps has parent organization: Carnegie Mellon University; Pennsylvania; USA |
Merck Company Foundation ; NIGMS GM075205; NCI R33 CA83219; NSF MCB-8920118 |
THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-33313 | SCR_008663 | PSLID - Protein Subcellular Location Image Database, Protein Subcellular Location Image Database | 2026-02-17 10:01:23 | 0 | ||||||
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BMAP - Brain Molecular Anatomy Project Resource Report Resource Website 1+ mentions |
BMAP - Brain Molecular Anatomy Project (RRID:SCR_008852) | BMAP | data or information resource, topical portal, portal, funding resource | The Brain Molecular Anatomy Project is a trans-NIH project aimed at understanding gene expression and function in the nervous system. BMAP has two major scientific goals: # Gene discovery: to catalog of all the genes expressed in the nervous system, under both normal and abnormal conditions. # Gene expression analysis: to monitor gene expression patterns in the nervous system as a function of cell type, anatomical location, developmental stage, and physiological state, and thus gain insight into gene function. In pursuit of these goals, BMAP has launched several initiatives to provide resources and funding opportunities for the scientific community. These include several Requests for Applications and Requests for Proposals, descriptions of which can be found in this Web site. BMAP is also in the process of establishing physical and electronic resources for the community, including repositories of cDNA clones for nervous system genes, and databases of gene expression information for the nervous system. Most of the BMAP initiatives so far have focused on the mouse as a model species because of the ease of experimental and genetic manipulation of this organism, and because many models of human disease are available in the mouse. However, research in humans, other mammalian species, non-mammalian vertebrates, and invertebrates is also being funded through BMAP. For the convenience of interested investigators, we have established this Web site as a central information resource, focusing on major NIH-sponsored funding opportunities, initiatives, genomic resources available to the research community, courses and scientific meetings related to BMAP initiatives, and selected reports and publications. When appropriate, we will also post initiatives not directly sponsored by BMAP, but which are deemed relevant to its goals. Posting decisions are made by the Trans-NIH BMAP Committee |
has parent organization: National Institutes of Health is parent organization of: BMAP cDNA Resources |
Aging | NINDS ; NIMH ; NIDA ; NEI ; NIA ; NIAAA ; NICHD ; NIDCD ; NIEHS ; NHGRI ; NIGMS |
nlx_149083 | SCR_008852 | Brain Molecular Anatomy Project, Trans-NIH Brain Molecular Anatomy Project | 2026-02-17 10:01:26 | 6 | |||||||
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Community Structure-Activity Resource Resource Report Resource Website 10+ mentions |
Community Structure-Activity Resource (RRID:SCR_002206) | CSAR | storage service resource, data or information resource, service resource, data set, data repository | Experimental datasets of crystal structures and binding affinities for diverse protein-ligand complexes. Some datasets are generated in house while others are collected from the literature or deposited by academic labs, national centers, and the pharmaceutical industry. For the community to improve their approaches, they need exceptional datasets to train scoring functions and develop new docking algorithms. They aim to provide the highest quality data for a diverse collection of proteins and small molecule ligands. They need input from the community in developing target priorities. Ideal targets will have many high-quality crystal structures (apo and 10-20 bound to diverse ligands) and affinity data for 25 compounds that range in size, scaffold, and logP. It is best if the ligand set has several congeneric series that span a broad range of affinity, with low nanomolar to mid-micromolar being most desirable. They prefer Kd data over Ki data over IC50 data (no % activity data). They will determine solubility, pKa, logP/logD data for the ligands whenever possible. They have augmented some donated IC50 data by determining Kon/Koff and ITC data. | crystal structure, binding affinity, protein-ligand complex, protein, small molecule, ligand, compound |
is used by: NIF Data Federation is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) has parent organization: University of Michigan; Ann Arbor; USA |
NIGMS | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_154720 | SCR_002206 | 2026-02-17 09:59:52 | 15 | |||||||
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Simtk.org Resource Report Resource Website 10+ mentions |
Simtk.org (RRID:SCR_002680) | SimTK | software application, software resource, simulation software, software repository | A National NIH Center for Biomedical Computing that focuses on physics-based simulation of biological structures and provides open access to high quality simulation tools, accurate models and the people behind them. It serves as a repository for models that are published (as well as the associated code) to create a living archive of simulation scholarship. Simtk.org is organized into projects. A project represents a research endeavor, a software package or a collection of documents and publications. Includes sharing of image files, media, references to publications and manuscripts, as well as executables and applications for download and source code. Simulation tools are free to download and space is available for developers to manage, share and disseminate code. | model, modeling, rna folding, protein folding, myosin dynamics, neuromuscular biomechanics, cardiovascular dynamics, biomolecular simulation, biomedical computing, repository, cardiovascular, neuromuscular, myosin, rna, simulation, biocomputation |
is used by: NIF Data Federation lists: Adaptively Sampled Particle Fluids lists: OpenMM lists: CPODES numerical integrator is listed by: Biositemaps is listed by: Integrated Models is listed by: DataCite is listed by: re3data.org is related to: OpenSim is related to: Simbody(tm): SimTK Multibody Dynamics Toolset is related to: SimVascular is related to: SAFA Footprinting Software is related to: Ion Simulator Interface is related to: LAPACK linear algebra library is related to: Neuromuscular Models Library has parent organization: Simbios is parent organization of: FEATURE is parent organization of: Cardiovascular Model Repository is parent organization of: ConTrack is parent organization of: Allopathfinder is parent organization of: Molecular Simulation Trajectories Archive of a Villin Variant is parent organization of: LAPACK linear algebra library is parent organization of: SimTKCore |
NIH ; NIGMS U54 GM072970 |
Free, Available for download, Freely available | nif-0000-23302, DOI:10.17616/R3QJ4B, DOI:10.18735 | https://doi.org/10.17616/R3QJ4B https://doi.org/10.17616/r3qj4b https://doi.org/10.18735/ https://dx.doi.org/10.18735/ |
SCR_002680 | Simulation Toolkit, SimTK - the Simulation Toolkit | 2026-02-17 10:00:01 | 18 | |||||
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BioPortal Resource Report Resource Website 100+ mentions |
BioPortal (RRID:SCR_002713) | BioPortal | ontology, repository, storage service resource, data or information resource, controlled vocabulary, service resource, data repository | Open repository of biomedical ontologies that provides access via Web browsers and Web services to ontologies. It supports ontologies in OBO format, OWL, RDF, Rich Release Format (RRF), Protege frames, and LexGrid XML. Functionality includes the ability to browse, search and visualize ontologies as well as to comment on, and create mappings for ontologies. Any registered user can submit an ontology. The NCBO Annotator and NCBO Resource Index can also be accessed via BioPortal. Additional features: * Add Reviews: rate the ontology according to several criteria and describe your experience using the ontology. * Add Mappings: submit point-to-point mappings or upload bulk mappings created with external tools. Notification of new Mappings is RSS-enabled and Mappings can be browsed via BioPortal and accessed via Web services. * NCBO Annotator: Tool that tags free text with ontology terms. NCBO uses the Annotator to generate ontology annotations, creating an ontology index of these resources accessible via the NCBO Resource Index. The Annotator can be accessed through BioPortal or directly as a Web service. The annotation workflow is based on syntactic concept recognition (using the preferred name and synonyms for terms) and on a set of semantic expansion algorithms that leverage the ontology structure (e.g., is_a relations). * NCBO Resource Index: The NCBO Resource Index is a system for ontology based annotation and indexing of biomedical data; the key functionality of this system is to enable users to locate biomedical data linked via ontology terms. A set of annotations is generated automatically, using the NCBO Annotator, and presented in BioPortal. This service uses a concept recognizer (developed by the National Center for Integrative Biomedical Informatics, University of Michigan) to produce a set of annotations and expand them using ontology is_a relations. * Web services: Documentation on all Web services and example code is available at: BioPortal Web services. | biomedical, thesaurus, ontology mapping, annotation, metadata standard, ontology repository, portal, web service, obo, owl, rdf, rrf protege frame, lexgrid xml |
lists: MeGO lists: Porifera Ontology lists: EnvO lists: Research Network and Patient Registry Inventory Ontology lists: Semantic DICOM Ontology lists: Time Event Ontology lists: Variation Ontology lists: Vertebrate Skeletal Anatomy Ontology lists: Epoch Clinical Trial Ontology lists: Gazetteer lists: Human Disease Ontology lists: Information Artifact Ontology lists: NCBITaxon lists: Amphibian Taxonomy Ontology lists: Anatomic Pathology Lexicon lists: HIV ontology lists: International Classification of Primary Care - 2 PLUS lists: Mathematical Modelling Ontology lists: Nursing Interventions Classification lists: Phylogenetic Ontology lists: Bleeding History Phenotype Ontology lists: Body System Terms from ICD11 lists: Synthetic Biology Open Language Visual Ontology lists: Teleost Anatomy Ontology lists: Teleost Taxonomy Ontology lists: ECO lists: Bioassay Ontology lists: RightField lists: Gene Ontology lists: HGNC lists: Interaction Ontology lists: International Classification for Nursing Practice lists: Spider Ontology lists: Vertebrate Trait Ontology lists: Mental Functioning Ontology lists: Ascomycete Phenotype Ontology lists: Beta Cell Genomics Ontology lists: Biological Collections Ontology lists: Chemical Methods Ontology lists: Chemical Information Ontology lists: Common Anatomy Reference Ontology lists: Experimental Conditions Ontology lists: Dictyostelium Discoideum Anatomy Ontology lists: Fission Yeast Phenotype Ontology lists: Fly Taxonomy lists: FlyBase Controlled Vocabulary lists: Hymenoptera Anatomy Ontology lists: Influenza Ontology lists: Lipid Ontology lists: Kinetic Simulation Algorithm Ontology lists: Malaria Ontology lists: FMA lists: Minimal Anatomical Terminology lists: NEMO Ontology lists: Ontology for Genetic Interval lists: Ontology for Parasite LifeCycle lists: Ontology of Adverse Events lists: Ontology of Medically Related Social Entities lists: Ontology of Vaccine Adverse Events lists: Rat Strain Ontology lists: Plant Environmental Conditions lists: Plant Trait Ontology lists: Population and Community Ontology lists: RNA Ontology lists: Rat Strain Ontology lists: Subcellular Anatomy Ontology lists: Software Ontology lists: Suggested Ontology for Pharmacogenomics lists: Vertebrate Taxonomy Ontology lists: PharmGKB Ontology lists: Physico-Chemical Process lists: International Classification for Patient Safety lists: Adverse Event Reporting Ontology lists: Experimental Factor Ontology lists: Mass Spectrometry Ontology lists: Master Drug Data Base Clinical Drugs lists: Medaka Fish Anatomy and Development Ontology lists: Medical Diagnostic Categories - Diagnosis Related Groups lists: Medical Dictionary for Regulatory Activities lists: Minimal Standard Terminology of Digestive Endoscopy lists: Minimal Standard Terminology of Digestive Endoscopy - French lists: Ontology of Physical Exercises lists: Mosquito Gross Anatomy Ontology lists: Systematized Nomenclature of Medicine - International Version lists: Mosquito Insecticide Resistance Ontology lists: Mouse Experimental Design Ontology lists: Mouse Gross Anatomy and Development Ontology lists: Systematized Nomenclature of Medicine - Clinical Terms lists: Systems Chemical Biology and Chemogenomics Ontology lists: Mouse Pathology Ontology lists: NIF Cell Ontology lists: NHS Quality Indicators lists: Neural-Immune Gene Ontology lists: Ontology of Physics for Biology lists: Cell Type Ontology lists: Xenopus Anatomy Ontology lists: SO lists: Ontology of Pneumology lists: Open Biological and Biomedical Ontologies Relationship Types lists: Biomedical Resource Ontology lists: MGED Ontology lists: Pharmacovigilance Ontology lists: PhenX Phenotypic Terms lists: Bioinformatics Web Service Ontology lists: SysMO JERM Ontology of Systems Biology for Micro-Organisms lists: MeSH lists: PATO lists: BFO lists: MPO lists: PR lists: Cereal Plant Development Ontology lists: PhenomeBLAST Ontology lists: VIVO lists: Computer Assisted Brain Injury Rehabilitation Ontology lists: Computer Retrieval of Information on Scientific Projects Thesaurus lists: NIFSTD lists: Cell Line Ontology lists: Student Health Record Ontology lists: Zebrafish Anatomical Ontology lists: Physical Medicine and Rehabilitation lists: Randomized Controlled Trials Ontology lists: Human Phenotype Ontology lists: Read Codes Clinical Terms Version 3 lists: Reference Sequence Annotation lists: Regulation of Gene Expression Ontolology lists: Neurobehavior Ontology lists: Regulation of Transcription Ontology lists: Reproductive Trait and Phenotype Ontology lists: Skin Physiology Ontology lists: Vaccine Ontology lists: OMIM lists: MedlinePlus lists: Adult Mouse Anatomy Ontology lists: Bone Dysplasia Ontology lists: Bone and Cartilage Tissue Engineering Ontology lists: Botryllus schlosseri anatomy and development ontology lists: EDAM Ontology lists: LexGrid lists: RxNorm lists: Breast Cancer Grading Ontology lists: Breast Tissue Cell Lines Ontology lists: SBO lists: Resource of Asian Primary Immunodeficiency Diseases Phenotype Ontology lists: Brucellosis Ontology lists: Sleep Domain Ontology lists: C. elegans Development Vocabulary lists: Physician Data Query lists: C. elegans Gross Anatomy Vocabulary lists: Plant Ontology lists: C. elegans Phenotype Vocabulary lists: CPTAC Proteomics Pipeline Infrastructure Ontology lists: Cancer Research and Management ACGT Master Ontology lists: Cancer Chemoprevention Ontology lists: Cell Behavior Ontology lists: Cereal Plant Gross Anatomy Ontology lists: Cardiac Electrophysiology Ontology lists: Cerebrotendinous Xanthomatosis Ontology lists: Cell Cycle Ontology lists: Cell Culture Ontology lists: Cerrado concepts and plant community dynamics lists: Clinical Signs and Symptoms Ontology lists: Clusters of Orthologous Groups Analysis Ontology lists: Computational Neuroscience Ontology lists: BIRNLex lists: Computer-Based Patient Record Ontology lists: Congenital Heart Defects Ontology lists: Drug Interaction Knowledge Base Ontology lists: Healthcare Common Procedure Coding System lists: Host Pathogen Interactions Ontology lists: Human Dermatological Disease Ontology lists: Solanaceae Phenotype Ontology lists: Soy Ontology lists: Spatial Ontology lists: Surgical Secondary Events lists: eagle-i research resource ontology lists: Biological Pathways Exchange lists: Autism Spectrum Disorder Phenotype Ontology lists: BRENDA Tissue and Enzyme Source Ontology lists: BioTop Ontology lists: Family Health History Ontology lists: International Classification of Diseases Version 9 - Clinical Modification lists: BioModels Ontology lists: Bilingual Ontology of Alzheimer lists: BioPortal Metadata Ontology lists: Biochemical Substructure Ontology lists: Biodiversity Ontology lists: Biological Imaging Methods Ontology lists: International Classification of Functioning Disability and Health lists: Biologie Hors Nomenclature lists: International Classification of Primary Care lists: Biomedical Research Integrated Domain Group Model lists: KB Bio 101 lists: Bionutrition Ontology lists: Artificial Intelligence Rheumatology Consultant System Ontology lists: Leukocyte Surface Marker Ontology lists: Cell Line Ontology by Mahadevan lists: Cellular microscopy phenotype ontology lists: ABA Adult Mouse Brain Ontology lists: AEO lists: African Traditional Medicine Ontology lists: Alzheimer's disease ontology lists: Amino Acid Ontology lists: Amphibian Gross Anatomy Ontology lists: Animal Natural History and Life History Ontology lists: Coding Symbols for a Thesaurus of Adverse Reaction Terms lists: Cognitive Atlas Ontology lists: Common Terminology Criteria for Adverse Events lists: Comparative Data Analysis Ontology lists: Content Archive Resource Exchange Lexicon lists: Crop Ontology lists: Current Procedural Terminalogy Hierarchy lists: Current Procedural Terminology lists: DICOM Controlled Terminology lists: Dataset processing lists: Dengue Fever Ontology lists: Dermatology Lexicon lists: Diagnosis Ontology of Clinical Care Classification lists: Diagnostic Ontology lists: Disease core ontology applied to Rare Diseases lists: Dispedia Core Ontology lists: Drosophila Development Ontology lists: Drosophila Gross Anatomy Ontology lists: EDDA Study Design Terminology lists: Electrocardiography Ontology lists: Eligibility Feature Hierarchy lists: Enzyme Mechanism Ontology lists: Enzyme Reaction Ontology for partial chemical perspectives lists: Epilepsy Ontology lists: Loggerhead Nesting Ontology lists: Fanconi Anemia Ontology lists: Fire Ontology lists: Flora Phenotype Ontology lists: Fungal Gross Anatomy Ontology lists: Human Developmental Anatomy Ontology abstract version 1 lists: G Protein-Coupled Receptor BioAssays Ontology lists: Galen Ontology lists: Gene Expression Ontology lists: Gene Ontology Extension lists: General Formal Ontology lists: General Formal Ontology for Biology lists: Genome Component Ontology lists: Genomic Clinical Decision Support Ontology lists: GeoSpecies Ontology lists: Glycomics Ontology lists: Habronattus Courtship Ontology lists: Health Indicator Ontology lists: Health Level Seven Reference Implementation Model Version 3 lists: Human Developmental Anatomy Ontology abstract version 2 lists: Human Developmental Anatomy Ontology timed version lists: Human Interaction Network Ontology lists: Human Physiology Simulation Ontology lists: Logical Observation Identifier Names and Codes lists: IMGT-ONTOLOGY lists: Image and Data Quality Assessment Ontology lists: Immune Disorder Ontology lists: Infectious Disease Ontology lists: InterNano Nanomanufacturing Taxonomy lists: Interaction Network Ontology lists: International Classification of External Causes of Injuries lists: International Classification of Diseases Version 10 lists: International Classification of Diseases Version 10 - Clinical Modification lists: International Classification of Diseases Version 10 - Procedure Coding System lists: MR dataset acquisition lists: Maize Gross Anatomy Ontology lists: Major Histocompatibility Complex Ontology lists: Medical image simulation lists: Menelas Project Top-Level Ontology lists: Mental State Assessment lists: Metagenome Sample Vocabulary lists: Metagenome and Microbes Environmental Ontology lists: MicroRNA Ontology lists: Microbial Culture Collection Vocabulary lists: Microbial Typing Ontology lists: Minimal Information about any Sequence Controlled Vocabularies lists: Minimal Information about any Sequence Ontology lists: NIF Dysfunction Ontlogy lists: NIF Subcellular Ontology lists: NMR-Instrument Component of Metabolomics Investigations Ontology lists: Name Reaction Ontology lists: NanoParticle Ontology lists: National Cancer Institute Thesaurus lists: National Drug Data File lists: National Drug File - Reference Terminology lists: Natural Products Ontology lists: Neglected Tropical Disease Ontology lists: Neomark Oral Cancer Ontology version 3 lists: Neomark Oral Cancer Ontology version 4 lists: Neural Motor Recovery Ontology lists: NeuroMorpho.Org species ontology lists: NeuroMorpho.Org species ontology old lists: Non-Randomized Controlled Trials Ontology lists: Nursing Care Coordination Ontology lists: Ontological Knowledge Base Model for Cystic Fibrosis lists: Ontology for Drug Discovery Investigations lists: Ontology for General Medical Science lists: Ontology for Genetic Disease Investigations lists: Ontology for Genetic Susceptibility Factor lists: Ontology for MicroRNA Target Prediction lists: Symptom Ontology lists: Ontology for Newborn Screening Follow-up and Translational Research lists: Ontology of Alternative Medicine French lists: Ontology of Biological and Clinical Statistics lists: Ontology of Clinical Research lists: Ontology of Core Data Mining Entities lists: Ontology of Data Mining Investigations lists: Pediatric Terminology lists: Ontology of Experimental Variables and Values lists: Ontology of General Purpose Datatypes lists: Ontology of Geographical Region lists: Ontology of Glucose Metabolism Disorder lists: Ontology of Homology and Related Concepts in Biology lists: Ontology of Language Disorder in Autism lists: Orphanet Rare Disease Ontology lists: Parasite Experiment Ontology lists: Pathogen Transmission Ontology lists: Pathogenic Disease Ontology lists: Pharmacogenomic Relationships Ontology lists: Physico-Chemical Methods and Properties lists: Plant Anatomy lists: Syndromic Surveillance Ontology lists: Plant Structure Development Stage lists: Portfolio Management Application lists: Protein Modification Ontology lists: Protein-Protein Interaction Ontology lists: Proteomics Data and Process Provenance Ontology lists: Provenance Ontology lists: QUDT lists: Quantitative Imaging Biomarker Ontology lists: Radiology Lexicon lists: Robert Hoehndorf Version of MeSH lists: Role Ontology lists: STATistics Ontology lists: Sage Bionetworks Synapse Ontology lists: Sample Processing and Separation Techniques Ontology lists: Santa Barbara Coastal Observation Ontology lists: Semantic Types Ontology lists: Semantic Web for Earth and Environment Technology Ontology lists: Semanticscience Integrated Ontology lists: Single-Nucleotide Polymorphism Ontology lists: Situation-Based Access Control Ontology lists: Taxonomic Rank Vocabulary lists: Taxonomy for Rehabilitation of Knee Conditions lists: Terminological and Ontological Knowledge Resources Ontology lists: Tick Gross Anatomy Ontology lists: Tissue Microarray Ontology lists: Traditional Medicine Constitution Value Set lists: Traditional Medicine Meridian Value Sets lists: Traditional Medicine Other Factors Value Set lists: Traditional Medicine Signs and Symptoms Value Set lists: Translational Medicine Ontology lists: Tribolium Ontology lists: Units Ontology lists: Units of Measurement Ontology lists: Upper-Level Cancer Ontology lists: Vertebrate Homologous Organ Group Ontology lists: Veterans Health Administration National Drug File lists: Vital Sign Ontology lists: WHO Adverse Reaction Terminology lists: Web-Service Interaction Ontology lists: Wheat Trait Ontology lists: XEML Environment Ontology lists: suicideo lists: suicideonto lists: Pseudogene lists: Terminology for the Description of Dynamics lists: Gene Regulation Ontology lists: UBERON lists: CHEBI lists: Cognitive Paradigm Ontology lists: Emotion Ontology lists: Clinical Measurement Ontology lists: Measurement Method Ontology lists: NCI Thesaurus lists: Ontology for Biomedical Investigations lists: Biological Pathways Exchange is listed by: Biositemaps is listed by: FORCE11 is related to: Provisional Cell Ontology has parent organization: National Center for Biomedical Ontology has parent organization: Stanford University; Stanford; California has parent organization: Stanford Center for Biomedical Informatics Research is parent organization of: NCBO Annotator |
NIGMS U24 GM143402 | PMID:19483092 PMID:21672956 PMID:18999306 |
Free, Available for download, Freely available | nif-0000-23346, r3d100012344 | https://www.force11.org/node/4646 https://doi.org/10.17616/R3J362 |
SCR_002713 | BioPortal Knowledgebase | 2026-02-17 09:59:50 | 328 | ||||
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Molecular Simulation Trajectories Archive of a Villin Variant Resource Report Resource Website |
Molecular Simulation Trajectories Archive of a Villin Variant (RRID:SCR_002704) | Molecular Simulation Trajectories Archive of a Villin Variant | data or information resource, d spatial image, data set | An archive of hundreds of all-atom, explicit solvent molecular dynamics simulations that were performed on a set of nine unfolded conformations of a variant of the villin headpiece subdomain (HP-35 NleNle). It includes scripts for accessing the archive of villin trajectories as well as a VMD plug-in for viewing the trajectories. In addition, all starting structures used in the trajectories are also provided. The simulations were generated using a distributed computing method utilizing the symmetric multiprocessing paradigm for individual nodes of the Folding_at_home distributed computing network. The villin trajectories in the archive are divided into two projects: PROJ3036 and PROJ3037. PROJ3036 contains trajectories starting from nine non-folded configurations. PROJ3037 contains trajectories starting from the native (folded) state. Runs 0 through 8 (in PROJ3036) correspond to starting configurations 0 through 8 discussed in the paper in J. Mol. Biol. (2007) 374(3):806-816 (see the publications tab for a full reference), whereas RUN9 uses the same starting configuration as RUN8. Each run contains 100 trajectories (named clone 0-99), each with the same starting configuration but different random velocities. Trajectories vary in their length of time and are subdivided into frames, also known as a generation. Each frame contains around 400 configurational snapshots, or timepoints, of the trajectory, with the last configurational snapshot of frame i corresponding to the first configurational snapshot of generation i+1. The goal is to allow researchers to analyze and benefit from the many trajectories produced through the simulations. | dynamic, atom, headpiece, molecular, simulation, solvent, protein folding, villin, molecule, trajectory, simulation, molecular dynamics trajectory |
is listed by: Biositemaps has parent organization: Simtk.org |
Stanford University; California; USA ; Graduate Fellowship ; NIH ; NIGMS R01-GM062868; NSF MCB-0317072 |
PMID:17950314 | Acknowledgement requested, Available in Gromacs and PDB formats. | nif-0000-23331 | SCR_002704 | 2026-02-17 10:00:01 | 0 | ||||||
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Cytoscape Resource Report Resource Website 10000+ mentions |
Cytoscape (RRID:SCR_003032) | software application, data processing software, data analysis software, software resource, data visualization software | Software platform for complex network analysis and visualization. Used for visualization of molecular interaction networks and biological pathways and integrating these networks with annotations, gene expression profiles and other state data. | biological, network, visualization, analysis, data, gene, pathway, molecular, interaction, FASEB list |
is used by: CytoSPADE is used by: HDBase is used by: DisGeNET is used by: categoryCompare lists: PEPPER is listed by: Debian is listed by: SoftCite is related to: PhosphoSitePlus: Protein Modification Site is related to: TRIP Database is related to: CoryneRegNet is related to: AltAnalyze - Alternative Splicing Analysis Tool is related to: MiMI Plugin for Cytoscape is related to: Network Data Exchange (NDEx) is related to: GeneMANIA is related to: DroID - Drosophila Interactions Database is related to: Network-based Prediction of Human Tissue-specific Metabolism is related to: Biological General Repository for Interaction Datasets (BioGRID) is related to: DaTo is related to: PiNGO is related to: iBIOFind is related to: cPath is related to: BiNGO: A Biological Networks Gene Ontology tool is related to: ClueGO is related to: RamiGO is related to: EGAN: Exploratory Gene Association Networks has parent organization: Institute for Systems Biology; Washington; USA has parent organization: University of California at San Diego; California; USA is parent organization of: JEPETTO has plug in: CluePedia Cytoscape plugin has plug in: CytoSPADE has plug in: EnrichmentMap has plug in: cytoHubba works with: NetCirChro works with: IMEx - The International Molecular Exchange Consortium works with: yFiles Layout Algorithms works with: RCy3 |
National Resource for Network Biology ; NCRR RR031228; NIGMS GM070743 |
PMID:21149340 PMID:14597658 |
Free, Available for download, Freely available | nif-0000-30404 | https://sources.debian.org/src/cytoscape/ | SCR_003032 | Complex Network Analysis Visualization, Cytoscape 2.6, Cytoscape 3.0 | 2026-02-17 09:59:55 | 23431 | |||||
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TOPSAN Resource Report Resource Website 10+ mentions |
TOPSAN (RRID:SCR_005758) | TOPSAN | storage service resource, data or information resource, image collection, database, service resource, data repository | Collect, share, and distribute information about protein three-dimensional structures. It serves as a portal for the scientific community to learn about protein structures solved by SG centers, and also to contribute their expertise in annotating protein function. The premise of the TOPSAN project is that, no matter how much any individual knows about a particular protein, there are other members of the scientific community who know more about certain aspects of the same protein, and that the collective analyses from experts will be far more informative than any local group, let alone individual, could contribute. They believe that, if the members of the biological community are given the opportunity, authorship incentives, and an easy way to contribute their knowledge to the structure annotation, they would do so. Therefore, borrowing elements from successful, distributed, collaborative projects, such as Wikipedia (the free encyclopedia anyone can edit) and from other open source software development projects, TOPSAN will be a broad, collaborative effort to annotate protein structures, initially, those determined at the JCSG. They believe that the annotation of proteins solved by structural genomics consortia offers a unique opportunity to challenge the extant paradigm of how biological data is collected and distributed, and to connect structural genomics and structural biology to the entire biological research community. TOPSAN is designed to be scalable, modular and extensible. Furthermore, it is intended to be immediately useful in a simplistic way and will accommodate incremental improvements to functionality as usage becomes more sophisticated. Their annotation pages will offer the end user a combination of automatically generated as well as expert-curated annotations of protein structures. They will use available technology to increase the speed and granularity of the exchange of scientific ideas, and use incentive mechanisms that will encourage collaborative participation. | protein, structure, 3d, protein structure, protein function, annotate, crowd sourcing, image, annotation, genomics, collaboration |
has parent organization: Sanford Burnham Prebys Medical Discovery Institute has parent organization: University of California at San Diego; California; USA |
NIGMS U54 GM074898; NIGMS P20 GM076221 |
PMID:20961957 PMID:20716366 PMID:20944203 PMID:20961957 |
Creative Commons Attribution v3 License, The community can contribute to this resource | nlx_149221 | SCR_005758 | he Open Protein Structure Annotation Network, TOPSAN Project, TOPSAN - The Open Protein Structure Annotation Network | 2026-02-17 10:00:48 | 10 | |||||
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NIGMS Multimedia Resource Report Resource Website |
NIGMS Multimedia (RRID:SCR_005712) | NIGMS Multimedia | data or information resource, narrative resource, podcast, video resource | As part of its multimedia outreach, the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health -- the United States'' medical research agency -- offers audio and video podcasts and other multimedia resources that explore the exciting world of basic biomedical research. | basic research, biomedical research, biomedical | has parent organization: National Institute of General Medical Sciences | NIGMS | nlx_149379 | SCR_005712 | NIGMS Media Gallery, NIGMS - Multimedia, NIGMS - Media Gallery | 2026-02-17 10:00:58 | 0 | |||||||
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ChemHealthWeb Resource Report Resource Website |
ChemHealthWeb (RRID:SCR_005851) | ChemHealthWeb | narrative resource, data or information resource, topical portal, video resource, training material, portal | Visit ChemHealthWeb for research highlights, chemist profiles, games and videos and other Web extras. The NIGMS Chemistry of Health booklet describes basic chemistry and biochemistry research that spurs a better understanding of human health. | chemistry, health, chemistry, biochemistry, research, human, game, puzzle, chemist, molecule, medicine, teacher | has parent organization: National Institute of General Medical Sciences | NIGMS | nlx_149382 | SCR_005851 | 2026-02-17 10:00:49 | 0 | ||||||||
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Polbase Resource Report Resource Website |
Polbase (RRID:SCR_006107) | storage service resource, data or information resource, database, service resource, data repository | Repository of biochemical, genetic, and structural information about DNA Polymerases. Polbase is designed to compile detailed results of polymerase experimentation, presenting them in a dynamic view to inform further research. After validation, results from references are displayed in context with relevant experimental details and are always traceable to their source publication. Polbase is connected to other resources, including PubMed, UniProt and the RCSB Protein Data Bank, to provide multi-faceted views of polymerase knowledge. In addition to a simple web interface, Polbase data is exposed for custom analysis by external software. | dna polymerase repository, bio.tools |
is listed by: Debian is listed by: bio.tools is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) is related to: PubMed is related to: UniProt has parent organization: New England Biolabs |
Small Business Innovation Research ; NIGMS 1R44GM087021 |
PMID:21993301 | Free, Open unspecified license, Acknowledgement required | biotools:polbase, nlx_151580 | https://bio.tools/polbase | SCR_006107 | DNA Polymerase Database | 2026-02-17 10:01:00 | 0 | |||||
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QTL Archive Resource Report Resource Website 1+ mentions |
QTL Archive (RRID:SCR_006213) | QTL Archive | storage service resource, data or information resource, service resource, data set, data repository | Raw data from various QTL (quantitative trait loci) studies using rodent inbred line crosses. Data are available in the .csv format used by R/qtl and pseudomarker programs. In some cases analysis scripts and/or results are posted to accompany the data. These data are provided as a courtesy to the genetic mapping community and may be used for purposes of developing or testing new analysis methods or software and for meta-analysis of quantitative traits. The authors of the datasets retain individual ownership of the data. As a courtesy to the authors, please alert them in advance of any publications that result from reanalysis of these data or obtain permission prior to redistribution of data or results. In all data sets and files, the marker locations have been translated to Cox build 37 coordinates unless otherwise stated. Please consider contributing your data to the QTL Archive. | quantitative trait locus, inbred rat strain, phenotype, cross, genetics, inbreeding, genetic marker, quantitative genetics |
is listed by: re3data.org has parent organization: Jackson Laboratory |
NIGMS R01 GM070683 | The community can contribute to this resource | r3d100010571, nlx_151757 | https://doi.org/10.17616/R3C02Z | http://qtlarchive.org/ | SCR_006213 | Quantitative Trait Loci (QTL) Archive, Quantitative Trait Loci Archive | 2026-02-17 10:01:01 | 6 | ||||
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PSICQUIC Registry Resource Report Resource Website 10+ mentions |
PSICQUIC Registry (RRID:SCR_006389) | PSICQUIC | data access protocol, web service, software resource | Web service with well defined methods to enable programmatic access to molecular interactions. Standard for computational access to molecular interaction data resources. | molecular interaction, soap, rest, miql, programmatic access to molecular interactions |
is used by: mentha is related to: Interaction Reference Index is related to: IMEx - The International Molecular Exchange Consortium is related to: Reactome is related to: InnateDB has parent organization: HUPO Proteomics Standards Initiative |
German National Genome Research Network ; European Union Serving Life-science Information for the Next Generation ; European Union Proteomics Standards Initiative and International Molecular Exchange ; European Union Apoptosis Systems Biology Applied to Cancer and AIDS ; European Union Experimental Network for Functional Integration ; NIGMS R01GM071909; Italian Association for Cancer Research ; Wellcome Trust Strategic Award to the European Molecular Biology Laboratory ; European Bioinformatics Institute for Chemogenomics Databases ; Foundation for the National Institutes of Health and Genome British Columbia |
PMID:21716279 | Free, Freely available | nlx_152188, nlx_152189, SCR_006392 | http://code.google.com/p/psicquic/ | SCR_006389 | Protemics Standard Initiative Common QUery InterfaCe, PSI common query interface | 2026-02-17 10:00:51 | 30 | ||||
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map3d Resource Report Resource Website 1+ mentions |
map3d (RRID:SCR_009628) | map3d | data visualization software, data processing software, software application, software resource | A scientific visualization application written to display and edit complex, three-dimensional geometric models and scalar, time-based data associated with those models such as high resolution EEG, MEG, and ECG. | c++, eeg, meg, electrocorticography, forward - inverse, linux, macos, microsoft, modeling, posix/unix-like, visualization, win32 (ms windows), windows, windows 95/98/2000 |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) has parent organization: University of Utah; Utah; USA |
NCRR 5P41RR012553-15; NIGMS 8 P41 GM103545-15 |
Map3d License | nlx_155857 | http://www.nitrc.org/projects/map3d | SCR_009628 | 2026-02-17 10:01:32 | 3 | ||||||
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Datamonkey Resource Report Resource Website 1000+ mentions |
Datamonkey (RRID:SCR_010278) | data access protocol, source code, software resource, web service | Web-based suite of phylogenetic analysis tools for use in evolutionary biology. Web application for comparative analysis of sequence alignments using statistical models. Used for analyzing evolutionary signatures in sequence data. Datamonkey 2.0 provides curated collection of methods for interrogating coding-sequence alignments for imprints of natural selection, packaged as a responsive (i.e. can be viewed on tablet and mobile devices), fully interactive, and API-enabled web application. | comparative analysis of sequence alignments, analyzing evolutionary signatures, sequence data, | has parent organization: University of California at San Diego; California; USA | NIGMS R01 GM093939; NIGMS U01 GM110749; NSF ; NIAID AI43638; NIAID AI47745; NIAID AI57167; University of California at San Diego ; Canadian Institutes of Health Research |
PMID:15713735 PMID:20671151 PMID:29301006 |
Free, Available for download, Freely available | nlx_156937 | https://github.com/veg/datamonkey-js | SCR_010278 | , Datamonkey 2.0, datamonkey.org | 2026-02-17 10:01:41 | 1120 | |||||
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TargetScan Resource Report Resource Website 10000+ mentions |
TargetScan (RRID:SCR_010845) | data access protocol, production service resource, analysis service resource, service resource, software resource, web service, data analysis service | Web tool to predict biological targets of miRNAs by searching for presence of conserved 8mer, 7mer and 6mer sites that match seed region of each miRNA. Nonconserved sites are also predicted and sites with mismatches in seed region that are compensated by conserved 3' pairing. Used to search for predicted microRNA targets in mammals. | predict, biological, target, miRNA, conserved, 8mer, 7mer, site, match seed, region, nonconserved, mismatched, pair |
is listed by: OMICtools is listed by: SoftCite has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; |
NIGMS GM067031; Howard Hughes Medical Institute ; NSF Graduate Research Fellowship |
PMID:26267216 | Free, Freely available | OMICS_00420 | http://www.targetscan.org/vert_71/ | SCR_010845 | TargetScanFly | 2026-02-17 10:01:52 | 10783 | |||||
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Conservation Resource Report Resource Website 1000+ mentions |
Conservation (RRID:SCR_016064) | software application, software resource, software toolkit | Software for scoring protein sequence conservation using the Jensen-Shannon divergence. It can be used to predict catalytic sites and residues near bound ligands. | scoring, protein, sequence, conservation, Jensen-Shannon, divergence, predict, catalytic, site, bound, ligands, clustal, fasta, concave | is related to: Princeton University; New Jersey; USA | NIH T32 HG003284; NSF IIS-0612231; NSF PECASE MCB-0093399; NIGMS GM076275; NIH P50 GM071508 |
PMID:17519246 | Free, Available for download | SCR_016064 | Conservation-code | 2026-02-16 09:48:56 | 1564 | |||||||
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SAINTexpress Resource Report Resource Website 10+ mentions |
SAINTexpress (RRID:SCR_018562) | software resource, software toolkit | Software tool for upgraded implementation of probabilistic scoring of affinity purification mass spectrometry data. Used for filtering high confidence interaction data from affinity purification mass spectrometry experiments. Used for assigning confidence scores to protein-protein interactions based on quantitative proteomics data in AP-MS experiments. | Probabilistic scoring, affinity purification, mass spectrometry data, mass spectrometry experiment data, assigning confidence score, protein-protein interaction, quantitative proteomic data | NCRR R01 RR024031; NIGMS R01 GM094231; NCI R01 CA126239 |
PMID:24513533 | Free, Freely available | SCR_018562 | Significance Analysis of INTeractome Express | 2026-02-16 09:49:30 | 13 | ||||||||
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PyRosetta Resource Report Resource Website 10+ mentions |
PyRosetta (RRID:SCR_018541) | software application, software resource, standalone software | Interactive Python based interface to Rosetta molecular modeling suite. Stand alone Python based implementation of Rosetta molecular modeling package that allows users to write custom structure prediction and design algorithms using major Rosetta sampling and scoring functions. | Molecular modeling, custom structure prediction, design algorithm, energy function, scoring function, bio.tools |
uses: Python Programming Language is listed by: bio.tools is listed by: Debian is related to: Rosetta has parent organization: Johns Hopkins University; Maryland; USA |
NIGMS R01 GM73151; NIGMS R01 GM078221; NSF 0846324 |
PMID:20061306 | Free, Freely available | biotools:pyrosetta | https://bio.tools/pyrosetta | SCR_018541 | Python Rosetta | 2026-02-16 09:49:32 | 20 | |||||
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Sparse Inverse Covariance Estimation for Ecological Association Inference Resource Report Resource Website 10+ mentions |
Sparse Inverse Covariance Estimation for Ecological Association Inference (RRID:SCR_022646) | SPIEC-EASI | software resource, software toolkit | Software R package estimates inverse covariance matrix from sequencing data.Statistical method for inference of microbial ecological networks from amplicon sequencing datasets. | inverse covariance matrix estimation, sequencing data, microbial ecological networks inference, amplicon sequencing datasets microbial ecological networks, | NIAID T32AI007180; NIDDK R01 DK103358; NIGMS RO1 GM63270; Simons Foundation |
PMID:25950956 | Free, Available for download, Freely available | SCR_022646 | SParse InversE Covariance Estimation for Ecological Association Inference | 2026-02-16 09:50:28 | 12 |
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