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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://brcf.medicine.umich.edu/cores/bioinformatics-core/
Core helps researchers identify and interpret patterns in RNA and DNA by placing sequencing data into biologically meaningful context. Services include experimental design, developing reproducible workflows, analyzing next-generation sequencing data, and supporting manuscript development/publication.
Proper citation: University of Michigan Medical School Bioinformatics Core (RRID:SCR_019168) Copy
NIH-funded resource that provides information about how human genetic variation affects response to medications. PharmGKB collects, curates and disseminates knowledge about clinically actionable gene-drug associations and genotype-phenotype relationships.
Proper citation: PharmKGB (RRID:SCR_025580) Copy
https://sparc.science/about/consortia/precision
Project titled Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins, and Nature of Human Pain (PRECISION) Network to develop meaningful resource for knowledge transfer, and to integrate and share Human Pain Associated Genes and Cell Datasets. Building knowledge platform to visualize, query, and interact with these data will support researchers and help accelerate dissemination of vital data to the larger scientific community. These goals align with NIH Helping to End Addiction Long-term (HEAL) Initiative, which seeks to accelerate the discovery and successful translation of non-addictive pain therapeutics. PRECISION Human Pain Network will leverage prior interdisciplinary collaboration to create workflows, tools, and infrastructure to define data and metadata types, to improve data management and sharing, and to integrate datasets and visualization tools.
Proper citation: NIH PRECISION Human Pain Network (RRID:SCR_025458) Copy
https://github.com/jefftc/changlab
Software system for performing bioinformatics analyses. System includes knowledge base where the capabilities of bioinformatics software is explicitly and formally encoded. Backwards-chaining rule-based expert system comprised of data model that can capture richness of biological data, and inference engine that reasons on knowledge base to produce workflows. Knowledge base is populated with rules to analyze microarray and next generation sequencing data.
Proper citation: BETSY (RRID:SCR_026239) Copy
SOCR designs, validates and freely disseminates knowledge. The Resource develops AI/ML tools, mathematical models, and end-to-end data analytic protocols for biomedical and health studies. It provides portable online aids for probability, statistics and health science education, promotes technology enhanced instruction, supports efficient statistical computing, supports AI-services, and advances predictive big data analytics. The SOCR platform includes repository of interactive apps, datasets and case-studies, computational tools, visualization approaches, instructional resources, learning materials, and curricular components. SOCR faculty, staff, and students support data and information science collaborations and analytic partnerships involving biomedical, healthcare, and biostatistical investigations.
Proper citation: University of Michigan Statistics Online Computational Resource Core Facility (RRID:SCR_022917) Copy
https://www.cores.emory.edu/iemc/
Core helps investigators use the latest technologies on structural research in their projects. Provides expertise in experimental needs.
Proper citation: Emory University Robert P. Apkarian Integrated Electron Microscopy Core Facility (RRID:SCR_023537) Copy
https://nationalmaglab.org/user-facilities/icr
Facility provides service operations for sample analysis that requires ultrahigh resolution and high mass accuracy of Fourier Transform Ion Cyclotron Resonance. Used for research in biomolecular analysis, hydrogen-deuterium exchange and environmental and petrochemical analysis. Four FT-ICR mass spectrometers feature high magnetic fields including the world-record 21 tesla and are compatible with multiple ionization and fragmentation techniques.
Proper citation: National High Magnetic Field Laboratory Ion Cyclotron Resonance Core Facility (RRID:SCR_017361) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/flow-cytometry/index.html
Provides central location for flow cytometry instrumentation and education. Services include Flow Cytometry,Cell sorting, data analysis, training. Software packages to analyze data include ModFit LT, BD FACSDiva v6, Cell Quest Pro, and FlowJo vX, from facility workstations.
Proper citation: Nebraska University Medical Center Flow Cytometry Research Core Facility (RRID:SCR_017736) Copy
https://nationalmaglab.org/user-facilities/emr/
EMR Facility offers home-built, high-frequency and high-field continuous-wave instruments providing frequency coverage from 9 GHz to 1 THz, with additional frequencies available up to 2.5 THz using molecular gas laser. EMR covers variety of magnetic resonance techniques associated with electron like Electron Paramagnetic/Spin Resonance (EPR/ESR). EPR/ESR can be performed on any sample that has unpaired electron spins and used in applications in physics, materials science, chemistry and biology, including studies of impurity states, molecular clusters, antiferromagnetic, ferromagnetic and thin film compounds, natural or induced radicals, optically excited paramagnetic states, electron spin-based quantum information devices, transition-metal based catalysts; and for structural and dynamical studies of metallo-proteins, spin-labeled proteins and other complex bio-molecules and their synthetic models.
Proper citation: National High Magnetic Field Laboratory Electron Magnetic Resonance Core Facility (RRID:SCR_017359) Copy
https://nationalmaglab.org/user-facilities/dc-field
Facility located at MagLab headquarters near Florida State University in Tallahassee. Contains 14 resistive magnet cells connected to 56 megawatt DC power supply and 15,000 square feet of cooling equipment to remove heat generated by magnets. Includes several superconducting magnets operating at millikelvin temperatures. Among these instruments is 45-tesla hybrid magnet, which offers scientists strongest continuous magnetic field in world. Research is supported by magnet plant and cryogenic system operators. Technicians design, build and repair instruments for user research.
Proper citation: National High Magnetic Field Lab DC Field Core Facility (RRID:SCR_017358) Copy
Core mass spec and proteomic services include open access lab for trained users with GC/MS, LC/MS, high resolution LC/MS, and MALDI-TOF instruments, help with intact protein analysis, targeted quantitation, drug discovery support, pathway analysis, protein interactions, FFPE tissue analysis, both labeled and label-free proteomics, and more. Please contact SUMS to discuss these and other custom projects including new application development.
Proper citation: Stanford University Vincent Coates Foundation Mass Spectrometry Laboratory Core Facility (RRID:SCR_017801) Copy
http://www.columbia.edu/cu/biology/resources/proteomics/
Core provides identification of proteins and metabolites with differential quantitative expression in cells, tissues or in protein affinity purifications. Particular emphasis is on quantitative analysis of posttranslational modifications such as phosphorylation.
Proper citation: Columbia University Quantitative Proteomics and Metabolomics Core Facility (RRID:SCR_017747) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/microscopy-laboratory
Core offers comprehensive light and electron microscopy technologies. Our scientists use light microscopes and electron microscopes at resolutions ranging from centimeters to angstroms, providing clear and detailed images.We assist at every stage of your experiment, offering research-design consultation and instrument training, as well as guidance in study execution, analysis, and presentation for publication.
Proper citation: New York University School of Medicine Langone Health Microscopy Laboratory Core Facility (RRID:SCR_017934) Copy
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