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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://sourceforge.net/projects/dhacdist/
Software for clustering time-evolving networks.
Proper citation: DHAC (RRID:SCR_012139) Copy
http://xmsanalyzer.sourceforge.net
A software package of utilities for data extraction, quality control assessment, detection of overlapping and unique metabolites in multiple datasets, and batch annotation of metabolites. xMSanalyzer comprises of utilities that can be classified into five main modules: 1) merging apLCMS or XCMS sample processing results from multiple sets of parameter settings, 2) evaluation of sample quality, feature consistency, and batch-effect, 3) feature matching, and 4) characterization of m/z using KEGG REST; 5) Batch-effect correction using ComBat.
Proper citation: xMSanalyzer (RRID:SCR_012144) Copy
http://sourceforge.net/projects/atlas-link/
Software that implements a greedy algorithm and uses graph theory to link and orient assembled existing contigs quickly and accurately using mate pair information.
Proper citation: Next-gen Sequencing Scaffolding Tool (RRID:SCR_006762) Copy
http://sourceforge.net/projects/quasr/
A lightweight software pipeline written to process and analyse next-generation sequencing (NGS) data from Illumina, 454, and Ion Torrent platforms. Although originally written for viral data, it is generic enough to work on any NGS dataset. Functions include: duplicate removal, demultiplexing, primer-removal, quality-assurance (QA) graphing, quality control (QC), consensus-generation, minority-variant determination, minority-variant graphing.
Proper citation: QUASR (RRID:SCR_006820) Copy
http://sourceforge.net/projects/simhtsd/
Software that given a reference sequence, will create a large set of short nucleotide reads, simulating the output from today''s high-throughput DNA sequencers, such as the Illumina Genome Analyzer II.
Proper citation: simhtsd (RRID:SCR_006822) Copy
http://sourceforge.net/projects/virmid/
A Java based variant caller designed for disease-control matched samples. Virmid is also specialized for identifying potential within individual contamination where the disease sample cannot be purified enough. While the SNP calling rate is severely compromised with this heterogeneity, Virmid can uncover SNPs with low allele frequency by considering the level of contamination (alpha). The important features of Virmid are: * Estimation of accurate proporation of control sample in a (mixed) disease sample * Improved SNP and somatic mutation calling with regard to the estimated proportion
Proper citation: Virmid (RRID:SCR_006780) Copy
http://sourceforge.net/projects/bigpre/
A quality assessment software package for next-genomics sequencing data.
Proper citation: BIGpre (RRID:SCR_006781) Copy
http://sourceforge.net/projects/taxoassignement/
Software tool for the taxonomic assignment of Next Generation Sequencing reads using multiple reference taxonomy.
Proper citation: TaxoAssignement (RRID:SCR_006814) Copy
http://garm-meta-assem.sourceforge.net/
A new software pipeline to merge and reconcile assemblies from different algorithms or sequencing technologies.
Proper citation: GARM (RRID:SCR_006731) Copy
http://sourceforge.net/projects/powermap/
Software tool specifically designed for neuroimaging data that implements theoretical power calculation algorithms based on non-central random field theory. It can also calculate power for statistical analyses with FDR (false discovery rate) corrections. This GUI (graphical user interface)-based tool enables neuroimaging researchers without advanced knowledge in imaging statistics to calculate power and sample size in the form of 3D images. This tool is currently under limited release for beta testing. At this time, only users that have been directed to this site by the PowerMap developers will receive support.
Proper citation: PowerMap (RRID:SCR_006721) Copy
http://sourceforge.net/projects/samscope/
A lightweight SAM/BAM file viewer that makes visually exploring next generation sequencing data intuitive and maybe even fun! Quickly and easily generate aggregate statistics from SAM/BAM files like coverage, polarity, and minor allele frequencies, then scroll and explore freely with a simple mouse based interface. Multiple windows can be synchronized for careful comparison across multiple experiments.
Proper citation: Samscope (RRID:SCR_006715) Copy
http://sourceforge.net/projects/dmeas/
A user-friendly DNA methylation analysis tool for DNA methylation pattern extraction, DNA methylation level estimation, DNA methylation entropy analysis and multi-sample comparison. It was developed in order to assess the DNA methylation variations for a given genomic locus or genome-wide methylation data.
Proper citation: DMEAS (RRID:SCR_006679) Copy
http://sourceforge.net/projects/hiahia/
A sequence alignment tool to align both short and long reads to a reference genome. HIA has two indexes, a hash table index and a suffix array index. The hash table is capable of the direct lookup of a q-gram and the suffix array is very fast in the lookup of a variable length q-gram. Our experiments show that the hybrid of hash table and suffix array is useful at the perspective of speed to map NGS sequencing reads to a reference genome sequence.
Proper citation: HIA (RRID:SCR_006865) Copy
http://sourceforge.net/projects/fitgcp/
Software providing a framework for fitting mixtures of probability distributions to genome coverage profiles.
Proper citation: fitGCP (RRID:SCR_006741) Copy
http://sourceforge.net/projects/gasic/
A method to correct read alignment results for the ambiguities imposed by similarities of genomes.
Proper citation: GASiC (RRID:SCR_006765) Copy
http://mrfast.sourceforge.net/
Software designed to map short reads generated with the Illumina platform to reference genome assemblies; in a fast and memory-efficient mannerl. Currently Supported Features: * Output in SAM format * Indels up to 8 bp (4 bp deletions and 4 bp insertions) * Paired-end mapping ** Discordant option to generate mapping file ready for VariationHunter to detect structural variants. * One end anchored (OEA) map locations for novel sequence insertion detection with NovelSeq * Matepair library mapping (long inserts with RF orientation). Planned Features: * Multithreading
Proper citation: mrFAST (RRID:SCR_005487) Copy
http://sourceforge.net/projects/cushaw2/files/CUSHAW2-GPU/
Software program (based on CUSHAW2) designed and optimized for Kepler-based GPUs, but still workable on earlier-generation Fermi-based ones.
Proper citation: CUSHAW2-GPU (RRID:SCR_005480) Copy
http://cushaw2.sourceforge.net/homepage.htm#latest
Software package for next-generation sequencing read alignment that is fast and parallel gapped read alignment to large genomes, such as the human genome.
Proper citation: CUSHAW (RRID:SCR_005479) Copy
http://ngsview.sourceforge.net/
A generally applicable, flexible and extensible next-generation sequence alignment editor. The software allows for visualization and manipulation of millions of sequences simultaneously on a desktop computer, through a graphical interface.
Proper citation: NGSView (RRID:SCR_005637) Copy
http://samtools.sourceforge.net/tview.shtml
Text alignment viewer software based on the GNU ncurses library that works with short indels and shows MAQ consensus. It uses different colors to display mapping quality or base quality, subjected to users' choice.
Proper citation: SAMtools Text Alignment Viewer (RRID:SCR_005611) Copy
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