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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
BEETL-fastq
 
Resource Report
Resource Website
BEETL-fastq (RRID:SCR_002341) software resource Software tool that not only compresses FASTQ-formatted DNA reads more compactly than gzip but also permits rapid search for k-mer queries within the archived sequences. The full FASTQ record of each matching read or read pair is returned, allowing the search results to be piped directly to any of the many standard tools that accept FASTQ data as input. Searchable compressed archive for DNA reads. Searchable compressed archive, DNA reads, compresses FASTQ-formatted DNA reads, bio.tools, is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Burrows-Wheeler transform
PMID:24950811 Free, Available for download, Freely available OMICS_04900, biotools:beetl https://bio.tools/beetl SCR_002341 2026-02-14 02:00:16 0
CisGenome
 
Resource Report
Resource Website
50+ mentions
CisGenome (RRID:SCR_001558) data analysis tool Integrated software tool for tiling array, ChIP-seq, genome and cis-regulatory element analysis. sequencing software, chip seq, downstream analysis, chip analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
works with: TileMap
PMID:18978777 Free, Available for download, Freely available OMICS_00423, biotools:cisgenome https://bio.tools/cisgenome http://biogibbs.stanford.edu/~jihk/CisGenome/index.htm SCR_001558 CisGenome v2.0 2026-02-14 02:00:06 82
vsn
 
Resource Report
Resource Website
1+ mentions
vsn (RRID:SCR_001459) vsn software resource Software package that implements a method for normalizing microarray intensities, both between colours within array, and between arrays. The method uses a robust variant of the maximum-likelihood estimator for the stochastic model of microarray data described in the references. The model incorporates data calibration (a.k.a. normalization), a model for the dependence of the variance on the mean intensity, and a variance stabilizing data transformation. Differences between transformed intensities are analogous to normalized log-ratios. However, in contrast to the latter, their variance is independent of the mean, and they are usually more sensitive and specific in detecting differential transcription. microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
Free, Available for download, Freely available OMICS_01977, biotools:vsn https://bio.tools/vsn SCR_001459 vsn - Variance stabilization and calibration for microarray data 2026-02-14 02:00:09 5
DNACLUST
 
Resource Report
Resource Website
1+ mentions
DNACLUST (RRID:SCR_001771) software resource Software program for clustering large number of short similar DNA sequences. It was originally designed for clustering targeted 16S rRNA pyrosequencing reads. cluster, dna sequence, gene, 16s rrna pyrosequencing read, microbiome is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
has parent organization: SourceForge
PMID:21718538
DOI:10.1186/1471-2105-12-271
Free, Available for download, Freely available OMICS_01955 https://sources.debian.org/src/dnaclust/ SCR_001771 DNAClust 2026-02-14 02:00:10 9
InterMine
 
Resource Report
Resource Website
10+ mentions
InterMine (RRID:SCR_001772) software resource An open source data warehouse system built for the integration and analysis of complex biological data that enables the creation of biological databases accessed by sophisticated web query tools. Parsers are provided for integrating data from many common biological data sources and formats, and there is a framework for adding data. InterMine includes a user-friendly web interface that works "out of the box" and can be easily customized for specific needs, as well as a powerful, scriptable web-service API to allow programmatic access to data. mac os x, unix/linux, windows, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Cambridge; Cambridge; United Kingdom
Wellcome Trust PMID:24753429 Free, Freely available OMICS_03840, biotools:intermine https://github.com/intermine/intermine
https://bio.tools/intermine
http://intermine.github.io/intermine.org/ SCR_001772 2026-02-14 02:00:07 22
unifiedWMWqPCR
 
Resource Report
Resource Website
unifiedWMWqPCR (RRID:SCR_001706) software resource Software package that implements the unified Wilcoxon-Mann-Whitney Test for qPCR data. This modified test allows for testing differential expression in qPCR data. standalone software, mac os x, unix/linux, windows, r, gene expression, microtitre plate assay, qpcr, differential expression, multiple comparison, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24794933 Free, Available for download, Freely available OMICS_03937, biotools:unifiedwmwqpcr https://bio.tools/unifiedwmwqpcr SCR_001706 unifiedWMWqPCR - Unified Wilcoxon-Mann Whitney Test for testing differential expression in qPCR data 2026-02-14 02:00:16 0
CCAT
 
Resource Report
Resource Website
50+ mentions
CCAT (RRID:SCR_001843) CCAT software resource THIS RESOURCE IS OUT OF SERVICE, documented on April 5, 2017, A software package for the analysis of ChIP-seq data with negative control., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Genome Institute of Singapore; Singapore; Singapore
PMID:20371496 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00428, biotools:ccat https://bio.tools/ccat SCR_001843 Control based ChIP-Seq Analysis Tools 2026-02-14 02:00:09 76
S-MART
 
Resource Report
Resource Website
10+ mentions
S-MART (RRID:SCR_001908) S-MART software resource Software toolbox that manages your RNA-Seq and ChIP-Seq data and also produces many different plots to visualize your data. It performs several tasks that are usually required during the analysis of mapped RNA-Seq and ChIP-Seq reads, including data selection and data visualization. It includes the selection (or the exclusion) of the data that overlaps with a reference set, clustering and comparative analysis. It also provides many ways to visualize data: size of the reads, density on the genome, distance with respect to a reference set, and the correlation of two data sets (with cloud plots). A computer science background is not required to run it through a graphical interface and it can be run on any personal computer, yielding results within an hour for most queries. high throughput sequencing, rna-seq, chip-seq, python, linux, ms windows, mac, short-read, selection, visualization, bio.tools, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:21998740 Free, Available for download, Freely available OMICS_01937, biotools:mapperanalyzer, biotools:s-mart https://bio.tools/s-mart
https://bio.tools/mapperanalyzer
SCR_001908 2026-02-14 02:00:11 23
SamSPECTRAL
 
Resource Report
Resource Website
1+ mentions
SamSPECTRAL (RRID:SCR_001858) software resource Software that identifies cell population in flow cytometry data. It demonstrates significant advantages in proper identification of populations with non-elliptical shapes, low density populations close to dense ones, minor subpopulations of a major population and rare populations. It samples large data such that spectral clustering is possible while preserving density information in edge weights. More specifically, given a matrix of coordinates as input, SamSPECTRAL first builds the communities to sample the data points. Then, it builds a graph and after weighting the edges by conductance computation, the graph is passed to a classic spectral clustering algorithm to find the spectral clusters. The last stage of SamSPECTRAL is to combine the spectral clusters. The resulting connected components estimate biological cell populations in the data sample. software package, mac os x, unix/linux, windows, r, cell biology, clustering, flow cytometry, stem cell, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
Cancer, HIV PMID:20667133 Free, Available for download, Freely available OMICS_05638, biotools:samspectral https://bio.tools/samspectral SCR_001858 SamSPECTRAL - Identifies cell population in flow cytometry data 2026-02-14 02:00:13 4
CQN
 
Resource Report
Resource Website
1+ mentions
CQN (RRID:SCR_001786) CQN software resource A normalization tool for RNA-Seq data, implementing the conditional quantile normalization method. rna-seq, differential expression, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:22285995 Free, Available for download, Freely available OMICS_01949, biotools:cqn https://bio.tools/cqn SCR_001786 Conditional Quantile Normalization 2026-02-14 02:00:11 6
pFind Studio: pLink
 
Resource Report
Resource Website
10+ mentions
pFind Studio: pLink (RRID:SCR_000084) pLink software resource Software dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. mass spectrometry, proteomics, pFind Studio, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chinese Academy of Sciences; Beijing; China
PMID:22772728 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02404, biotools:pLink-2 https://github.com/pFindStudio/pLink3/releases http://pfind.ict.ac.cn/software/pLink/index.html SCR_000084 , pLink, pLink (pFind Studio), pLink2 2026-02-14 01:59:37 15
DNAcopy
 
Resource Report
Resource Website
100+ mentions
DNAcopy (RRID:SCR_012560) DNAcopy software resource Software that segments DNA copy number data using circular binary segmentation to detect regions with abnormal copy number. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
OMICS_00720, biotools:dnacopy https://bio.tools/dnacopy
https://sources.debian.org/src/r-bioc-dnacopy/
SCR_012560 2026-02-14 02:02:42 334
AutoDock
 
Resource Report
Resource Website
10000+ mentions
AutoDock (RRID:SCR_012746) autodock software resource Software suite of automated docking tools. Designed to predict how small molecules, such as substrates or drug candidates, bind to receptor of known 3D structure. AutoDock consist of AutoDock 4 and AutoDock Vina. AutoDock 4 consists of autodock to perform docking of ligand to set of grids describing target protein, and autogrid to pre calculate these grids. Small molecules receptor binding, automated docking tools, 3D structure, AutoDock 4, AutoDock Vina, ligand, docking is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Autogrid
PMID:19399780 Free, Available for download, Freely available OMICS_01594, biotools:autodock https://bio.tools/autodock
https://sources.debian.org/src/autodock/
SCR_012746 2026-02-14 02:02:16 11935
BEDOPS
 
Resource Report
Resource Website
100+ mentions
BEDOPS (RRID:SCR_012865) BEDOPS software resource A suite of tools to address common questions raised in genomic studies - mostly with regard to overlap and proximity relationships between data sets. is listed by: OMICtools
is listed by: Debian
PMID:22576172
DOI:10.1093/bioinformatics/bts277
GNU General Public License, v3 OMICS_00949 https://sources.debian.org/src/bedops/ SCR_012865 BEDOPS: high-performance genomic feature operations 2026-02-14 02:02:24 220
featureCounts
 
Resource Report
Resource Website
10000+ mentions
featureCounts (RRID:SCR_012919) featureCounts software resource A read summarization program, which counts mapped reads for the genomic features such as genes and exons. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is required by: SL-quant
PMID:24227677 biotools:featurecounts, OMICS_01160 https://bio.tools/featurecounts SCR_012919 featureCounts: a universal read summarization program 2026-02-14 02:02:48 12197
DEXSeq
 
Resource Report
Resource Website
500+ mentions
DEXSeq (RRID:SCR_012823) DEXSeq software resource Software package focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
OMICS_01329, biotools:dexseq https://bio.tools/dexseq SCR_012823 2026-02-14 02:02:23 506
RepeatMasker
 
Resource Report
Resource Website
5000+ mentions
RepeatMasker (RRID:SCR_012954) software resource Software tool that screens DNA sequences for interspersed repeats and low complexity DNA sequences. The output of the program is a detailed annotation of the repeats that are present in the query sequence as well as a modified version of the query sequence in which all the annotated repeats have been masked (default: replaced by Ns). Currently over 56% of human genomic sequence is identified and masked by the program. Sequence comparisons in RepeatMasker are performed by one of several popular search engines including nhmmer, cross_match, ABBlast/WUBlast, RMBlast and Decypher. RepeatMasker makes use of curated libraries of repeats and currently supports Dfam ( profile HMM library ) and RepBase ( consensus sequence library ). uses: Repbase
uses: RMBlast
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
DOI:10.1007/978-1-61779-603-6_2 nlx_156840, OMICS_09436 https://sources.debian.org/src/repeatmasker/ SCR_012954 repeatmasker.org 2026-02-14 02:02:48 9750
DNaseR
 
Resource Report
Resource Website
DNaseR (RRID:SCR_012819) DNaseR software resource A R package that enables the identification of protein binding footprints in DNase I hypersensitive sites sequencing (DNase-seq) data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:23118738 Free biotools:dnaser, OMICS_00517 https://bio.tools/dnaser SCR_012819 DNaseR: DNase I footprinting analysis of DNase-seq data 2026-02-14 02:02:47 0
Acacia
 
Resource Report
Resource Website
100+ mentions
Acacia (RRID:SCR_012896) Acacia software resource Accurate error-correction of amplicon pyrosequences. is listed by: OMICtools
is listed by: Debian
has parent organization: SourceForge
DOI:10.1038/nmeth.1990 OMICS_01116 https://sources.debian.org/src/acacia/ SCR_012896 2026-02-14 02:02:48 106
charm
 
Resource Report
Resource Website
50+ mentions
charm (RRID:SCR_012992) charm software resource Software package that implements analysis tools for DNA methylation data generated using Nimblegen microarrays and the McrBC protocol. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
biotools:charm, OMICS_00792 https://bio.tools/charm SCR_012992 2026-02-14 02:02:25 63

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