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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://databases.unesco.org/bioethics/biowebintro.shtml
Bioethics database comprises over 645 bioethics institutions (bioethics committees, commissions, training, research and documentation centres) in over 80 countries, including information on activities and publications. Information is based on replies obtained from a widely distributed questionnaire and has been gathered in cooperation with National Commissions and Permanent Delegations to UNESCO. The Program develops four main action areas: -Intellectual forum -Standard-setting action -Advisory role and capacity-building -Education and awareness raising The Bioethics Program is part of UNESCOs Division of the Ethics of Science and Technology in the Social and Human Sciences Sector. It is primarily responsible for the Secretariat of two advisory bodies: the International Bioethics Committee (IBC), composed of 36 independent experts, and the Intergovernmental Bioethics Committee (IGBC), composed of representatives of 36 Member States. These Committees cooperate to produce advice, recommendations and proposals that each submits to the Director-General for consideration by UNESCOs governing bodies.
Proper citation: Bioethics Institutes Database (RRID:SCR_008173) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, it has been replaced by Monarch Initiative. LAMHDI, the initiative to Link Animal Models to Human DIsease, is designed to accelerate the research process by providing biomedical researchers with a simple, comprehensive Web-based resource to find the best animal model for their research. LAMDHI is a free, Web-based, resource to help researchers bridge the gap between bench testing and human trials. It provides a free, unbiased resource that enables scientists to quickly find the best animal models for their research studies. LAMHDI includes mouse data from MGI, the Mouse Genome Informatics website; zebrafish data from ZFIN, the Zebrafish Model Organism Database; rat data from RGD, the Rat Genome Database; yeast data from SGD, the Saccharomyces Genome Database; and fly data from FlyBase. LAMHDI.org is operational today, and data is added regularly. Enhancements are planned to let researchers contribute their knowledge of the animal models available through LAMHDI. The LAMHDI goal is to allow researchers to share information about and access to animal models so they can refine research and testing, and reduce or replace the use of animal models where possible. LAMHDI Database Search: LAMHDI brings together scientifically validated information from various sources to create a composite multi-species database of animal models of human disease. To do this, the LAMHDI database is prepared from a variety of sources. The LAMHDI team takes publicly available data from OMIM, NCBI''s Entrez Gene database, Homologene, and WikiPathways, and builds a mathematical graph (think of it as a map or a web) that links these data together. OMIM is used to link human diseases with specific human genes, and Entrez provides universal identifiers for each of those genes. Human genes are linked to their counterpart genes in other species with Homologene, and those genes are linked to other genes tentatively or authoritatively using the data in WikiPathways. This preparatory work gives LAMHDI a web of human diseases linked to specific human genes, orthologous human genes, homologous genes in other species, and both human and non-human genes involved in specific metabolic pathways associated with those diseases. LAMHDI includes model data that partners provide directly from their data structures. For instance, MGI provides information about mouse models, including a disease for each model, as well as some genetic information (the ID of the model, in fact, identifies one or more genes). ZFIN provides genetic information for each zebrafish model, but no diseases, so zebrafish models are integrated by using the genes as the glue. For instance, a zebrafish model built to feature the zebrafish PKD2 gene would plug into the larger disease-gene map at the node representing the zebrafish PKD2 gene, which is connected to the node representing the human PKD2 gene, which in turn is connected to the node representing the human disease known as polycystic kidney disease. (Some of the partner data LAMHDI receives can even extend the base map. MGI provides a disease for every model, and in some cases this allows the creation of a disease-to-gene relationship in the LAMHDI database that might not already be documented in the OMIM dataset.) With curatorial and model information in hand, LAMHDI runs a lengthy automated process that exhaustively searches for every possible path between each model and each disease in the data, up to a set number of hops, producing for each disease-to-model pair a set of links from the disease to the model. The algorithm avoids circular paths and paths that include more than one disease anywhere in the middle of the path. At the end of this phase, LAMHDI has a comprehensive set of paths representing all the disease-to-model relationships in the data, varying in length from one hop to many hops. Each disease-to-model path is essentially a string of nodes in the data, where each node represents a disease, a gene, a linkage between genes (an orthologue, a homologue, or a pathway connection, referred to as a gene cluster or association), or a model. Each node has a human-friendly label, a set of terms and keywords, and - in most cases - a URL linking the node to the data source where it originated. When a researcher submits a search on the LAMHDI website, LAMHDI searches for the user''s search terms in its precomputed list of all known disease-to-model paths. It looks for the terms not only in the disease and model nodes, but also in every node along each path. The complete set of hits may include multiple paths between any given disease-to-model pair of endpoints. Each of these disease-to-model pair sets is ordered by the number of hops it involves, and the one involving the fewest hops is chosen to represent its respective disease-to-model pair in the search results presented to the user. Results are sorted by scores that represent their matches. The number of hops is one barometer of the strength of the evidence linking the model and the disease; fewer hops indicates the relationship is stronger, more hops indicates it may be weaker. This indicator works best for comparing models from a single partner dataset: MGI explicitly identifies a disease for each mouse model, so there can be disease-to-model hits for mice that involve just one hop. Because ZFIN does not explicitly identify a disease for each model, no zebrafish model will involve fewer than four hops to the nearest disease, from the zebrafish model to a zebrafish gene to a gene cluster to a human gene to a human disease.
Proper citation: LAMHDI: The Initiative to Link Animal Models to Human DIsease (RRID:SCR_008643) Copy
BioMedSearch is a biomedical search engine that contains NIH/PubMed documents, plus a large collection of theses, dissertations, and other publications not found anywhere else for free, making it the most comprehensive free search on the web. :Besides free-form search, users can search based on Author, Journal Title, Publication Date, the Language in which the article was published (many non-English articles have English language abstracts), MeSH (Medical Subject Headings) and more. : The goal of BioMedSearch.com is to provide free access to a massive collection of authoritative documents relating to the biomedical field. Our mission is to make these important works available to the community in a way that is fast and easy, while still offering the advanced features demanded by power users such as portfolios, collaboration features, bibliographical citation export, alerts, and more. Whether you are doctor, scientist, or someone interested in researching a medical topic out of personal interest, BioMedSearch aggregates a vast number of authoritative documents in one place to make finding medical information easy, fast and free.
Proper citation: Biomedical Search: Medical Research and Health Resources (RRID:SCR_008683) Copy
http://www.phac-aspc.gc.ca/msds-ftss/
Material Safety Data Sheets for chemical products are available to laboratory workers for most chemicals and reagents. However because many laboratory workers, whether in research, public health, teaching, etc., are exposed to not only chemicals but infectious substances as well, there was a large gap in the readily available safety literature for employees. These MSDS are produced for personnel working in the life sciences as quick safety reference material relating to infectious micro-organisms. The MSDS are organized to contain health hazard information such as infectious dose, viability (including decontamination), medical information, laboratory hazard, recommended precautions, handling information and spill procedures. The intent of these documents is to provide a safety resource for laboratory personnel working with these infectious substances. Because these workers are usually working in a scientific setting and are potentially exposed to much higher concentrations of these human pathogens than the general public, the terminology in these MSDS is technical and detailed, containing information that is relevant specifically to the laboratory setting. It is hoped along with good laboratory practices, these MSDS will help provide a safer, healthier environment for everyone working with infectious substances. The MSDS is ran by the Public Health Agency of Canada. The Public Health Agency of Canada (PHAC) is the main Government of Canada agency responsible for public health in Canada. PHACs primary goal is to strengthen Canadas capacity to protect and improve the health of Canadians and to help reduce pressures on the health-care system. To do this, the Agency is working to build an effective public health system that enables Canadians to achieve better health and well-being in their daily lives by promoting good health, helping prevent and control chronic diseases and injury, and protecting Canadians from infectious diseases and other threats to their health. PHAC is also committed to reducing health disparities between the most advantaged and disadvantaged Canadians. Because public health is a shared responsibility, the Public Health Agency of Canada works in close collaboration with all levels of government (provincial, territorial and municipal) to build on each others skills and strengths. The Agency also works closely with non-government organizations, including civil society and business, and other countries and international organizations like the World Health Organization (WHO) to share knowledge, expertise and experiences.
Proper citation: Material Safety Data Sheets for Infectious Substances of Canada (RRID:SCR_013003) Copy
http://faculty.washington.edu/anath/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. University of Washington - affiliated research lab focused on understanding the roles of protein dynamics in health and human disease. They focus on developing methods to characterize and control protein dynamics through utilizing methods like single-molecule fluorescence, computational modeling, and protein engineering. There is an emphasis on proteins involved in degenerative disorders such as Alzheimer's disease, stress responses and drug metabolism.
Proper citation: University of Washington Nath Research Group (RRID:SCR_000180) Copy
http://www.juntadeandalucia.es/fundacionprogresoysalud/es/home
An organization that supports the public health system in Andalusia, Spain through three main activities: research and innovation in health, technologies line information and communication, and training and evaluation of professional skills. It also provides management support to the Health Quality Agency of Andalusia, which is the driving entity of the Andalusian Quality Model. Resource is in Spanish.
Proper citation: Progress and Health Foundation; Seville; Spain (RRID:SCR_000276) Copy
http://nacet.org/az-core-labs/
A core facility which provides fee-based sample imaging and analysis using analytical and microscopy equipment to technology incubator clients, university researchers, and industry.
Proper citation: AZ Core Labs (RRID:SCR_001036) Copy
https://www.k-inbre.org/pages/k-inbre_about_bio-core.html
The K-INBRE Bioinformatics Core collaborates with Kansas researchers to perform research on cell and developmental biology. Core aims to serve the needs of investigators engaged in computationally intensive biomedical research, and to promote education in bioinformatics to students and researchers across the state of Kansas.
Proper citation: Kansas State University - INBRE Bioinformatics Core Facility (RRID:SCR_012596) Copy
A national research infrastructure that provides bioinformatics support to life science researchers in Sweden. Their work is supported by the Swedish Research Council.
Proper citation: Bioinformatics Infrastructure for Life Sciences (RRID:SCR_014723) Copy
An institute which provides infrastructure, services, and training to support clinical and translational research. It develops broad coalitions and partnerships at the local and national levels to enable a transformation of the research environment.
Proper citation: UCSF Clinical and Translational Science Institute (RRID:SCR_014711) Copy
http://www.lji.org/faculty-research/scientific-cores/dlac/#overview
The department of laboratory animal care at the La Jolla Institute for Allergy and Immunology.
Proper citation: La Jolla Institute for Allergy and Immunology Department of Laboratory Animal Care (RRID:SCR_014834) Copy
http://www.lji.org/faculty-research/scientific-cores/clinical-studies/#overview
Core facility for clinical studies carried out by the La Jolla Institute of Allergy and Immunology. It is also a non-profit research organization that focuses on studying topics lthat include pollen allergies, HIV, food allergies and tuberculosis.
Proper citation: La Jolla Institute for Immunology Clinical Studies Core Facility (RRID:SCR_014833) Copy
http://www.lji.org/faculty-research/scientific-cores/functional-genomics/#overview
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 5, 2024. Core facility that combines large-scale automation and high-throughput capabilities with gene disruption techniques to pinpoint the function of individual genes and find new ways to disrupt genetic triggers of disease. The research capabilities are aimed towards finding new treatments for immune-related diseases.
Proper citation: La Jolla Institute for Allergy and Immunology Functional Genomics Core Facility (RRID:SCR_014836) Copy
http://tuskegee.eagle-i.net/i/00000136-602c-f62d-ee37-018280000000
THIS RESOURCE IS NO LONGER IN SERVICE, documented January 23, 2019. Core Facility enhances multidisciplinary research infrastructure by providing resources, services and technical support. Solely for Tuskegee University. Primary goal is achieved by providing instrumentation and personnel in two Cores. Core One addresses the need for lab instrumentation and Core Two provides resources in the areas of bioinformatics, computational biology and information technology.
Proper citation: Tuskegee Center for Biomedical Research Shared Instrumentation Core (RRID:SCR_010064) Copy
A non-profit tissue bank that facilitates the distribution of non-transplantable tissue to the medical and research community. It provides snap frozen low post mortem interval (PMI) tissue, normal and diseased tissue, plastinated specimens, anatomical specimens, and specialty specimens. The foundation also works to increase public awareness of research tissue donation for medical research.
Proper citation: LifeLegacy Foundation (RRID:SCR_000518) Copy
A blog featuring articles on the brain, consciousness, cognitive science, psychology and neurology. This resource is in Russian.
Proper citation: Brain Mysteries (RRID:SCR_000504) Copy
Polish state sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading development of science across country by society of distinguished scholars and network of research institutes. Polish research institution comprised of smaller institutes with goal to support development of science and establishing standards of research quality and ethics.
Proper citation: Polish Academy of Sciences Warsaw; Warsaw; Poland (RRID:SCR_000250) Copy
http://www.creative-diagnostics.com/
An antibody supplier that also provides diagnostic components, assay reagents and contract biologic RandD and manufacturing services. The company focuses on providing services to help clients develop, manufacture and commercialize their products.
Proper citation: Creative Diagnostics (RRID:SCR_000367) Copy
A non-profit organization that facilitates the donation of tissues. It supports healthcare agencies, coroners, medical examiners and funeral professionals through donations and training, as well as partnering with organizations that utilize tissue in medical care and research.
Proper citation: American Tissue Services Foundation - ATSF (RRID:SCR_000549) Copy
Network of world class researchers and innovators to improve lives of people living in poverty by generating insights and tools for decision makers backed by rigorous, inclusive, and transparent research. Hub for research, training and innovation headquartered at University of California, Berkeley.
Proper citation: Center for Effective Global Action (RRID:SCR_024639) Copy
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