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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
tRNA Analysis of eXpression
 
Resource Report
Resource Website
1+ mentions
tRNA Analysis of eXpression (RRID:SCR_025486) tRAX software application, data processing software, data analysis software, software resource Software package built for in-depth analyses of tRNA-derived small RNAs (tDRs), mature tRNAs, and inference of RNA modifications from high-throughput small RNA sequencing data. Used for integrating analysis of tRNAs, tRNA-derived small RNAs, and tRNA modifications. tRNA-derived small RNAs, mature tRNAs, inference of RNA modifications, high-throughput small RNA sequencing data, has parent organization: University of California at Santa Cruz; California; USA NHGRI R01HG006753 DOI:10.1101/2022.07.02.498565
PMID:26214130
Free, Available for download, Freely available, SCR_025486 tRNA Analysis of eXpression (tRAX) 2026-02-15 09:23:53 3
WASP
 
Resource Report
Resource Website
1+ mentions
WASP (RRID:SCR_025497) source code, software toolkit, software resource Software allele-specific pipeline for unbiased read mapping and molecular QTL discovery. Allele-specific software for robust molecular quantitative trait locus discovery. molecular QTLs discovery, unbiased allele-specific read mapping and discovery, molecular QTLs, unbiased allele-specific read, mapping and discovery, Howard Hughes Medical Institute ;
NHGRI HG007036;
NHGRI HG006123;
NIMH MH101825;
NIGMS GM007197;
NSF
PMID:26366987 Free, Available for download, Freely available, SCR_025497 2026-02-15 09:23:01 3
SIMS
 
Resource Report
Resource Website
1+ mentions
SIMS (RRID:SCR_025787) software application, software resource Software label transfer tool for single-cell RNA sequencing analysis. Scalable, Interpretable Modeling for Single-cell RNA-seq data classification. label transfer, single-cell RNA sequencing analysis, single-cell RNA-seq data classification, Schmidt Futures ;
NHGRI 1RM1HG011543;
NSF ;
NIMH 1U24MH132628;
University of California Office of the President ;
QualcommInstitute
PMID:38823397 Free, Available for download, Freely available SCR_025787 scalable, interpretable machine learning for single cell 2026-02-15 09:23:06 2
compleasm
 
Resource Report
Resource Website
1+ mentions
compleasm (RRID:SCR_026370) source code, software resource Software genome completeness evaluation tool based on miniprot. genome completeness evaluation, genome, completeness evaluation, NHGRI R01HG010040;
Chan-Zuckerberg Initiative
PMID:37758247 Free, Available for download, Freely available SCR_026370 2026-02-15 09:24:10 8
RFMix
 
Resource Report
Resource Website
1+ mentions
RFMix (RRID:SCR_027030) software application, software resource Software tool for local ancestry and admixture inference. Discriminative Modeling Approach for Rapid and Robust Local-Ancestry Inference. Discriminative Modeling, local ancestry and admixture inference, NLM LM007033;
NHGRI 2R01HG003229;
NSF
PMID:23910464 Restricted SCR_027030 2026-02-15 09:23:29 5
PEPATAC
 
Resource Report
Resource Website
1+ mentions
PEPATAC (RRID:SCR_024758) software toolkit, software resource Software standardized pipeline for ATAC-seq data analysis with serial alignments. Leverages unique features of ATAC-seq data to optimize for speed and accuracy, and provides several unique analytical approaches. Downstream analysis is simplified by standard definition format, modularity of components, and metadata APIs in R and Python. Restartable, fault-tolerant, and can be run on local hardware, using any cluster resource manager, or in provided Linux containers. We also emphasize the advantage of aligning to the mitochondrial genome serially, which improves alignment and quality control metrics. Includes quality control plots, summary statistics, and variety of data formats. ATAC-seq analysis pipeline, ATAC-seq data, analysis, serial alignments, NHGRI RM1 HG007735;
NIGMS R35 GM128636;
Howard Hughes Medical Institute ;
American Society of Hematology
PMID:34859208 Free, Available for download, Freely available https://github.com/databio/PEPATAC/releases SCR_024758 2026-02-15 09:23:51 2
HiCDCPlus
 
Resource Report
Resource Website
1+ mentions
HiCDCPlus (RRID:SCR_025317) software toolkit, software resource Software package for Hi-C/HiChIP interaction calling and differential analysis using efficient implementation of HiC-DC statistical framework. Enables principled statistical analysis of Hi-C and HiChIP data sets. Enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP Hi-C/HiChIP interaction calling, differential analysis, statistical analysis of Hi-C and HiChIP data sets, systematic 3D interaction calls, NHGRI U01 HG009395;
NIDDK U01 DK128852
PMID:34099725 Free, Available for download, Freely available https://bitbucket.org/leslielab/hicdcplus/src/master/ SCR_025317 , HiC-DC+, Hi-C Direct Caller Plus, HiCDCPlus (HiC-DC+) 2026-02-15 09:23:49 1
longshot
 
Resource Report
Resource Website
1+ mentions
longshot (RRID:SCR_025318) source code, software resource Software variant calling tool for diploid genomes using long error prone reads such as Pacific Biosciences (PacBio) SMRT and Oxford Nanopore Technologies (ONT). Enables accurate variant calling in diploid genomes from single-molecule long read sequencing. Takes as input aligned BAM/CRAM file and outputs phased VCF file with variants and haplotype information. variant calling, diploid genomes, long error prone reads, single molecule long read sequencing, NHGRI R01 HG010149 DOI:10.1038/s41467-019-12493-y Free, Available for download, Freely available SCR_025318 2026-02-15 09:23:55 3
GenVisR
 
Resource Report
Resource Website
10+ mentions
GenVisR (RRID:SCR_027559) software toolkit, software resource Software R package for visualizing genomics data. Provides a user-friendly, flexible and comprehensive suite of tools for visualizing complex genomic data in three categories (small variants, copy number alterations and data quality) for multiple species of interest. visualizing genomics data, genomics, genomics data, small variants, copy number alterations, data quality, multiple species, NHGRI K99HG007940;
NCI K22CA188163
PMID:27288499 Free, Available for download, Freely available SCR_027559 2026-02-15 09:23:34 41
Cistrome
 
Resource Report
Resource Website
10+ mentions
Cistrome (RRID:SCR_000242) data access protocol, software resource, web service Web based integrative platform for transcriptional regulation studies. Transcriptional, regulation, Chip, data, analysis, genome, gene, expression, motif, mining, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
has parent organization: Harvard University; Cambridge; United States
Dana-Farber Cancer Institute High Tech and Campaign Technology Fund ;
National Basic Research Program of China ;
NHGRI HG004069;
NIDDK DK074967;
NIDDK DK062434
PMID:21859476 Free, Freely available SCR_017663, biotools:cistrome, OMICS_02173 http://cistrome.org/ap/root
https://bio.tools/cistrome
SCR_000242 Galaxy Cistrome 2026-02-16 09:45:13 16
sleuth
 
Resource Report
Resource Website
10+ mentions
sleuth (RRID:SCR_016883) software application, data processing software, data analysis software, software resource Software tool for analysis of RNA-Seq experiments for which transcript abundances have been quantified with kallisto. Used for the differential analysis of gene expression data that utilizes bootstrapping in conjunction with response error linear modeling to decouple biological variance from inferential variance. differential, analysis, RNA-Seq, data, gene, expression, bootstrapping, error, linear, modeling, decouple, biological, variance, inferential, bio.tools is listed by: Debian
is listed by: bio.tools
works with: kallisto
NIDDK R01 DK094699;
NHGRI R01 HG006129
PMID:28581496 Free, Available for download, Freely available biotools:sleuth, BioTools:sleuth https://bio.tools/sleuth
https://bio.tools/sleuth
https://bio.tools/sleuth
SCR_016883 2026-02-15 09:21:55 24
Salmon
 
Resource Report
Resource Website
100+ mentions
Salmon (RRID:SCR_017036) software application, data processing software, data analysis software, software resource Software tool for quantifying expression of transcripts using RNA-seq data. Provides fast and bias-aware quantification of transcript expression. Transcriptome-wide quantifier to correct for fragment GC-content bias. quantifying, expression, transcript, RNAseq, data, correct, fragment, GC, content, bias is listed by: Debian
is listed by: OMICtools
has parent organization: Stony Brook University; New York; USA
has parent organization: Carnegie Mellon University; Pennsylvania; USA
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
has parent organization: Harvard University; Cambridge; Massachusetts
Gordon and Betty Moore Foundation Data-Driven Discovery Initiative ;
NHGRI R21 HG006913;
NHGRI R01 HG007104;
Alfred P. Sloan Research ;
NCI T32 CA009337;
NHGRI R01 HG005220;
NSF BIO-1564917;
NSF CCF-1256087;
NSF CCF-1053918;
NSF EF-0849899
PMID:28263959 Free, Available for download, Freely available OMICS_09075 https://github.com/COMBINE-lab/salmon
https://sources.debian.org/src/salmon/
SCR_017036 2026-02-15 09:21:14 357
proMODMatcher
 
Resource Report
Resource Website
1+ mentions
proMODMatcher (RRID:SCR_017219) software application, data processing software, data analysis software, software resource Software tool as probabilistic multi omics data matching procedure to curate data, identify and correct data annotation and errors in large databases. Used to check potential labeling errors in profiles where number of cis relationships is small, such as miRNA and RPPA profiles. probabilistic, matching, curate, omic, data, identify, correct, error, large, database, analysis, sample, label, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Icahn School of Medicine at Mount Sinai; New York; USA
NHGRI U01 HG008451;
NIA R01 AG046170;
NIAID U19 AI118610
biotools:modmatcher https://bio.tools/modmatcher SCR_017219 probabilisticMulti Omics DataMatcher 2026-02-15 09:21:59 1
Juicer
 
Resource Report
Resource Website
100+ mentions
Juicer (RRID:SCR_017226) software application, data processing software, data analysis software, software resource Software platform for analyzing kilobase resolution Hi-C data. Open source tool for analyzing terabase scale Hi-C datasets. Allowes to transform raw sequence data into normalized contact maps. analysis, kilobase, resolution, Hi-C, data, terabase, dataset, transform, raw, sequence, normalized, contact, map has parent organization: Baylor College of Medicine; Houston; Texas NIH Office of the Director DP2 OD008540;
NHLBI U01 HL130010;
NSF PHY-1427654;
NHGRI HG006193;
Welch Foundation ;
Cancer Prevention Research Institute of Texas ;
NVIDIA Research Center Award ;
IBM University Challenge Award ;
Google Research Award ;
McNair Medical Institute Scholar Award ;
President Early Career Award in Science and Engineering ;
NHGRI HG003067;
PD Soros Fellowship
PMID:27467249 Free, Available for download, Freely available SCR_017226 2026-02-15 09:21:59 108
CloVR
 
Resource Report
Resource Website
10+ mentions
CloVR (RRID:SCR_005290) CloVR service resource, software resource A desktop application for push-button automated sequence analysis that can utilize cloud computing resources. CloVR is implemented as a single portable virtual machine (VM) that provides several automated analysis pipelines for microbial genomics, including 16S, whole genome and metagenome sequence analysis. The CloVR VM runs on a personal computer, utilizes local computer resources and requires minimal installation, addressing key challenges in deploying bioinformatics workflows. In addition CloVR supports use of remote cloud computing resources to improve performance for large-scale sequence processing. cloud computing, next-generation sequencing is listed by: OMICtools
has parent organization: University of Maryland; Maryland; USA
Amazon Web Services in Education Research Grants program ;
National Human Genome Research Institute ;
NHGRI RC2 HG005597-01;
NSF 0949201
PMID:21878105 OMICS_01216 SCR_005290 CloVR - Automated Sequence Analysis from Your Desktop, Cloud Virtual Resource 2026-02-15 09:18:56 26
zfishbook
 
Resource Report
Resource Website
1+ mentions
zfishbook (RRID:SCR_006896) zfishbook material resource, biomaterial supply resource Collection of revertible protein trap gene-breaking transposon (GBT) insertional mutants in zebrafish with active or cryopreserved lines from initially identified lines. Open to community-wide contributions including expression and functional annotation and represents world-wide central hub for information on how to obtain these lines from diverse members of International Zebrafish Protein Trap Consortium (IZPTC) and integration within other zebrafish community databases including Zebrafish Information Network (ZFIN), Ensembl and National Center for Biotechnology Information. Registration allows users to save their favorite lines for easy access, request lines from Mayo Clinic catalog, contribute to line annotation with appropriate credit, and puts them on optional mailing list for future zfishbook newletters and updates. gene-breaking transposon, expression-tagged, revertible mutation, gene, transposon, mutation, mutant, brain, muscle, skin, secretory, cardiac, brain line, muscle line, skin line, secretory line, cardiac line, plasmid, expression, functional annotation, gene-breaking transposon line, gene-break transposon mutagenesis, cell line, annotation, embryonic zebrafish, larval zebrafish, bio.tools is listed by: One Mind Biospecimen Bank Listing
is listed by: Debian
is listed by: bio.tools
is related to: Addgene
is related to: Zebrafish International Resource Center
has parent organization: Mayo Clinic Minnesota; Minnesota; USA
Mayo Clinic Cancer Center ;
Mayo Foundation ;
NIGMS GM63904;
NIDA DA14546;
NHGRI HG006431
PMID:22067444 Free, Freely available biotools:zfishbook, nlx_151613 https://bio.tools/zfishbook SCR_006896 book, z fish book, zfishbook, fish, z 2026-02-15 09:19:37 4
Hanalyzer
 
Resource Report
Resource Website
Hanalyzer (RRID:SCR_000923) software application, source code, software resource An open-source data integration system designed to assist biologists in explaining the results observed in genome-scale experiments as well as generating new hypotheses. It combines information extraction techniques, semantic data integration, and reasoning and facilitates network visualization. The Hanalyzer source code and binaries are available for download. genomic, visualization, reading, reasoning, reporting, throughput analyzer, data network has parent organization: University of Colorado Denver; Colorado; USA
has parent organization: SourceForge
NIDCR R01DE15191;
NLM R01LM008111;
NLM R01LM009254;
NIGMS R01GM083649;
NLM T15LM009451;
NHGRI 5R01HG004483-09
PMID:19325874 nlx_48287 SCR_000923 Hanalyzer: A 3R System 2026-02-15 09:18:01 0
CHISEL
 
Resource Report
Resource Website
1+ mentions
CHISEL (RRID:SCR_023220) CHISEL software application, software resource Software tool to infer allele and haplotype specific copy numbers in individual cells from low coverage single cell DNA sequencing data. Integrates weak allelic signals across individual cells, powering strength of single cell sequencing technologies to overcome weakness. Includes global clustering of RDRs and BAFs, and rigorous model selection procedure for inferring genome ploidy that improves both inference of allele specific and total copy numbers. infer allele and haplotype specific copy numbers, individual cells, low coverage single cell DNA sequencing data, weak allelic signals, weak signals integration, NHGRI R01HG007069;
NCI U24CA211000;
NSF CCF 1053753;
Chan Zuckerberg Initiative DAF grants ;
NCI P30CA072720;
O’Brien Family Fund for Health Research ;
Wilke Family Fund for Innovation
DOI:10.1038/s41587-020-0661-6 Free, Available for download, Freely available SCR_023220 Copy-number Haplotype Inference in Single-cell by Evolutionary Links 2026-02-15 09:23:01 2
MEGA
 
Resource Report
Resource Website
1000+ mentions
MEGA (RRID:SCR_000667) MEGA, MEGA6, MEGA4, MEGA 4, MEGA 11 software application, data processing software, software toolkit, sequence analysis software, data analysis software, software resource Software integrated tool for conducting automatic and manual sequence alignment, inferring phylogenetic trees, mining web based databases, estimating rates of molecular evolution, and testing evolutionary hypotheses. Used for comparative analysis of DNA and protein sequences to infer molecular evolutionary patterns of genes, genomes, and species over time. MEGA version 4 expands on existing facilities for editing DNA sequence data from autosequencers, mining Web-databases, performing automatic and manual sequence alignment, analyzing sequence alignments to estimate evolutionary distances, inferring phylogenetic trees, and testing evolutionary hypotheses. MEGA version 6 enables inference of timetrees, as it implements RelTime method for estimating divergence times for all branching points in phylogeny. comparative, analysis, DNA, protein, sequence, molecular, evolution, pattern, gene, genome, evolution, FASEB list has parent organization: Pennsylvania State University Japan Society for the Promotion of Science ;
NHGRI HG006039;
NHGRI HG002096;
Burroughs-Wellcome Fund ;
NIGMS R01GM126567;
NSF ABI 1661218;
NIGMS R35GM139504
DOI:10.1093/molbev/msab120
PMID:24132122
PMID:31904846
PMID:22923298
PMID:21546353
PMID:17488738
PMID:15260895
PMID:11751241
PMID:8019868
Free, Available for download, Freely available SCR_023017, nlx_156838 https://www.megasoftware.net/mega4/ SCR_000667 MEGA11, Molecular Evolutionary Genetics Analysis, Molecular Evolutionary Genetics Analysis 6, Molecular Evolutionary Genetics Analysis 4 2026-02-16 09:45:19 2763
MouseCyc
 
Resource Report
Resource Website
1+ mentions
MouseCyc (RRID:SCR_001791) MouseCyc data analysis service, analysis service resource, database, production service resource, service resource, data or information resource A manually curated database of both known and predicted metabolic pathways for the laboratory mouse. It has been integrated with genetic and genomic data for the laboratory mouse available from the Mouse Genome Informatics database and with pathway data from other organisms, including human. The database records for 1,060 genes in Mouse Genome Informatics (MGI) are linked directly to 294 pathways with 1,790 compounds and 1,122 enzymatic reactions in MouseCyc. (Aug. 2013) BLAST and other tools are available. The initial focus for the development of MouseCyc is on metabolism and includes such cell level processes as biosynthesis, degradation, energy production, and detoxification. MouseCyc differs from existing pathway databases and software tools because of the extent to which the pathway information in MouseCyc is integrated with the wealth of biological knowledge for the laboratory mouse that is available from the Mouse Genome Informatics (MGI) database. energy production, biosynthesis, cell, cellular, degradation, detoxification, metabolism, mouse, physiological, enzymatic reaction, gene, disease, genome, metabolic pathway, pathway, compound, enzymatic reaction, protein, rna, reaction, blast, human, mammal, genetic, genomic is related to: Mouse Genome Informatics (MGI)
is related to: Gene Ontology
has parent organization: Jackson Laboratory
NHGRI HG003622 PMID:19682380 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10303 SCR_001791 MouseCyc database, Mouse Genome Informatics: MouseCyc database 2026-02-16 09:45:35 9

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