Tools   Select Another Resource Report Type

http://www.mouse-genome.bcm.tmc.edu/ENU/MutagenesisProj.asp

THIS RESOURCE IS NO LONGER IN SERVICE. For updated mutant information, please visit MMRRC or The Jackson Laboratory. Produces, characterizes, and distributes mutant mouse strains with defects in embryonic and postembryonic development. The goal of the ENU Mutagenesis project III is to determine the function of genes on mouse Chromosome 11 by saturating the chromosome with recessive mutations. The distal 40 cM of mouse Chr 11 exhibits linkage conservation with human Chromosome 17. We are using the chemical N-ethyl-N-nitrosourea (ENU) to saturate wild type chromosomes with point mutations. By determining the function of genes on a mouse chromosome, we can extrapolate to predict function on a human chromosome. We expect many of the new mutants to represent models of human diseases such as birth defects, patterning defects, growth and endocrine defects, neurological anomalies, and blood defects. Because many of the mutations we expect to isolate may be lethal or detrimental to the mice, we are using a unique approach to isolate mutations. This approach uses a balancer chromosome that is homozygous lethal and carries a dominant coat color marker to suppress recombination over a reasonable interval.

Proper citation: Mouse Mutagenesis Center for Developmental Defects (RRID:SCR_007321) Copy   

•   Source: SciCrunch Registry

http://www.bic.mni.mcgill.ca/ServicesAtlases/NIHPD-obj2

An unbiased magnetic resonance imaging template brain volume for pediatric data from birth to 4.5y age range. These volumes were created using 317 scans from 108 children enrolled in the NIH-funded MRI study of normal brain development (Almli et al., 2007, Evans and Group 2006). Templates are constructed for different age ranges. Each age range includes an average T1w, T2w, PDw maps normalized between 0 and 100. Also each age range includes a binary brain mask. Tools for using these atlases can be found in the Software section.

Proper citation: NIHPD Objective 2 atlases (birth - 4.5 years) (RRID:SCR_008795) Copy   

•   Source: SciCrunch Registry

http://www.grc.nia.nih.gov/

A research program of the NIA which focuses on neuroscience, aging biology, and translational gerontology. The central focus of the program's research is understanding age-related changes in physiology and the ability to adapt to environmental stress, and using that understanding to develop insight about the pathophysiology of age-related diseases. The IRP webpage provides access to other NIH resources such as the Biological Biochemical Image Database, the Bioinformatics Portal, and the Baltimore Longitudinal Study of Aging., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: Intramural Research Program (RRID:SCR_012734) Copy   

•   Source: SciCrunch Registry

http://mrtools.mgh.harvard.edu/index.php/TBR

A tool for functional connectivity analysis of fcMRI data that maps functional data from individual sessions onto a priori spatial components from group level parcellations.

Proper citation: Template Based Rotation (RRID:SCR_012157) Copy   

•   Source: SciCrunch Registry

http://www.bsl.ece.vt.edu/index.php?page=ara-dataset

Dataset of structural MR images of 70 subjects collected during 2008-2010 across a wide range of ages. The dataset also contains resting state fMRI for most subjects. The structural images are T1 weighted, T2 weighted-FLAIR, 25 direction DTI, and the T1 mapping DESPOT [1] sequence. Reconstructed T1 maps for each subject are also available. The aquisition protocol was designed to study structural differences between young and older adults including both shape and intensity changes. Anonymized DICOM image sessions and processed images for each subject are available. The data is licensed under the Creative Commons Attribution License. It may be used freely for commercial, academic, or other use, as long as the original source is properly cited. http://www.bsl.ece.vt.edu/index.php?page=ara-dataset

Proper citation: Age Related Atrophy Dataset (RRID:SCR_009528) Copy   

•   Source: SciCrunch Registry

http://www.stemcure.com/stemcure.php?page=tissue-banking

Stunning scientific discoveries have opened the possibilities for us to preserve our unaltered youth and healthy genome almost indefinitely. To do this, we propose to our clients to allow us to isolate and cryopreserve a small piece of tissue from their body in our unique tissue bank via a simple skin biopsy procedure. Our methods provide 100% assurance that the tissues we preserve will remain viable, healthy and young. We guarantee that these tissues will correspond to the age and physical status from the time when they were collected and can be preserved for many decades to come. In that way we strive to accomplish mankind''s most important dream ������?? to stop the hands of time and reduce the effects of aging. We will bring to a standstill the genetic program that is encoded in our cells that cause us to age and grow older. What is unique about this procedure, from a biological perspective, is that even as a person continues to live longer and get older, at the same time, part of his body remains invariably young. This well-preserved critical piece of tissue contains all the vitally important genetic material that harnesses the potential for invigorating one''s health. It will play an essential role in the rehabilitation and rejuvenation of human beings in the future. Recent studies have shown that certain parts of our skin are the most optimal material to be used for our program. For this purpose we utilize fibroblasts, the cells of the connective tissues located at the bottom side of our epidermis. In order to properly extract fibroblasts from our skin we have to perform a basic skin biopsy procedure. If you decide to participate in our program, StemCure will send to you the standard Tissue Collection Kit. This Kit contains detailed instructions for how your doctor should perform the biopsy procedure, as well as all the necessary components for the collection and transportation of a biopsy sample. StemCure will immediately start processing your biopsy samples once they arrive by overnight shipment to one of our laboratory facilities. We perform this very elaborate procedure because we understand perfectly well that our ultimate goal is not just the preservation of your tissue samples, but rather their subsequent utilization for the production of embryonic stem cells, which is the next stage of our program. Before subjecting the samples of your tissue to freezing, we will use the skin tissue to initiate the growth of the cell culture. After initial testing of the cell culture for viability and physiological activity, we will start its preparation for cyropreservation. StemCure will do everything in its power to ensure that the ������??Youth Genome������?? of our clients is safely protected and will remain a viable source for their healthy disease-free future.

Proper citation: StemCure Tissue Banking (RRID:SCR_010538) Copy   

•   Source: SciCrunch Registry

http://www.nia.nih.gov/ResearchInformation/ScientificResources/LongitudinalStudies.htm

THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 11, 2015. A searchable database for epidemiologic research on aging changes across the lifespan. In 2003, the National Institute on Aging (NIA) established the Longitudinal Data on Aging (LDA) working group to assist with the development of research initiatives for identifying the physiologic and other types of factors across the lifespan, affecting onset and progression of disease with advancing age, as well as elucidation of protective factors contributing to exceptionally healthy aging. This database was developed based on input from the LDA working group which indicated that establishing a database of existing sources of longitudinal data on aging (e.g., ongoing longitudinal cohorts, longitudinal data sets, biospecimen repositories) would be a valuable resource for facilitating future research on aging changes across the lifespan. The longitudinal studies, data sets and repositories included in this database encompass a wide range of age groups (childhood to old age), studies in minority populations, as well as sources of longitudinal data existing in the United States and abroad. Our primary purpose for establishing this database is to provide a resource for potential applicants for grants to the NIA. No part of this database can be used for commercial purposes.

Proper citation: National Institute on Aging, Database of Longitudinal Studies (RRID:SCR_008259) Copy   

•   Source: SciCrunch Registry

http://brainmap.wisc.edu/monkey.html

NO LONGER AVAILABLE. Documented on September 17, 2019. A set of multi-subject atlas templates to facilitate functional and structural imaging studies of the rhesus macaque. These atlases enable alignment of individual scans to improve localization and statistical power of the results, and allow comparison of results between studies and institutions. This population-average MRI-based atlas collection can be used with common brain mapping packages such as SPM or FSL.

Proper citation: Rhesus Macaque Atlases for Functional and Structural Imaging Studies (RRID:SCR_008650) Copy   

•   Source: SciCrunch Registry

http://www.lisdatacenter.org/

A cross-national data archive located in Luxembourg that contains two primary databases: the Luxembourg Income Study Database (LIS Database) includes income microdata from a large number of countries at multiple points in time. The newer Luxembourg Wealth Study Database(LWS Database) includes wealth microdata from a smaller selection of countries. Both databases include labor market and demographic data as well. Our mission is to enable, facilitate, promote, and conduct cross-national comparative research on socio-economic outcomes and on the institutional factors that shape those outcomes. Since its beginning in 1983, the LIS has grown into a cooperative research project with a membership that includes countries in Europe, North America, and Australia. The database now contains information for more than 30 countries with datasets that span up to three decades. The LIS databank has a total of over 140 datasets covering the period 1968 to 2005. The primary objectives of the LIS are as follows: * Test the feasibility for creating a database containing social and economic data collected in household surveys from different countries; * Provide a method which allows researchers to use the data under restrictions required by the countries providing the data; * Create a system that allows research requests to be received from and returned to users at remote locations; and * Promote comparative research on the social and economic status of various populations and subgroups in different countries. Data Availability: The dataset is accessed globally via electronic mail networks. Extensive documentation concerning technical aspects of the survey data, variables list, and the social institutions of income provision in member countries are also available to users through the project Website. * Dates of Study: 1968-present * Study Features: International * Sample Size: 30+ Countries Link: * ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/00150

Proper citation: Luxembourg Income Study (RRID:SCR_008732) Copy   

•   Source: SciCrunch Registry

http://centerforaging.duke.edu/index.php?option=com_content&view=article&id=115&Itemid=152

The project has been collecting detailed panel data about the health, disability, demographic, family, socioeconomic, and behavioral risk-factors for mortality and healthy longevity of the oldest old, with a comparative sub-sample of younger elders, to examine the factors in healthy longevity. The baseline survey was conducted in 1998 and the follow-up surveys with replacement to compensate for deceased elders were conducted in 2000, 2002, 2005, and 2008, For each centenarian, one near-by octogenarian (aged 80-89) and one near-by nonagenarian (aged 90-99) of pre-designated age and sex were interviewed. Near-by is loosely defined it could be in the same village or street if available, or in the same town or in the same county or city. The idea was to have comparable numbers of male and female octogenarians and nonagenarians at each age from 80 to 99. In 2002, the study added a refresher sub-sample of 4,845 interviewees aged 65-79, and a sub-sample of 4,478 adult children (aged 35-65) of the elderly interviewees aged 65-110 in eight provinces Comparative study of intergenerational relationships in the context of rapid aging and healthy longevity between Mainland China and Taiwan is possible. At each wave, the longitudinal survivors were re-interviewed, and the deceased interviewees were replaced by additional participants. Data on mortality and health status before dying for the 12,136 elders aged 65-112 who died between the waves were collected in interviews with a close family member of the deceased. The study also included interviews and follow-ups with 4,478 elderly interviewees'''' children aged 35-65. * Dates of Study: 1998-2005 * Study Features: Longitudinal, International * Sample Size: ** 1998: 8,993 ** 2000: 11,199 ** 2002: 16,064 ** 2005: 14,923 Links * Data Archive, http://www.geri.duke.edu/china_study/CLHLS6.htm * ICPSR, http://www.icpsr.umich.edu/icpsrweb/NACDA/studies/03891

Proper citation: Chinese Longitudinal Healthy Longevity Survey (CLHLS) (RRID:SCR_008904) Copy   

•   Source: SciCrunch Registry

http://scienceblogs.com/neurotopia/

A neuro blog that is no longer updated but has interesting archives. Categories: * Academia * Activism * Addiction * Aging/Gerontology * Basic Science Posts * Behavioral Neuro * Blog Carnivals * CNS Diseases and Disorders * Cognition * Creationism / Intelligent Design * Evil Journal Club * Evolution * Friday Weird Science * Health Care / Medicine * Menopause * Natural Sciences * Neuroanatomy * Neuroscience * Philosophy * Physiology / Pharmacology * Politics/Policy * Primatology * Religion * Rocket Surgery * Samsara * SchadenFriday * Synaptic Misfires

Proper citation: ScienceBlogs Neurotopia (RRID:SCR_008934) Copy   

•   Source: SciCrunch Registry

http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/4050?geography=South+Carolina

The Charleston Heart Study (CHS) is a prospective cohort study of 2,283 subjects (1,394 whites, 889 blacks) in which risk factors of coronary disease have been examined for the past 43 years. The CHS began enrolling a random selection of community residents who in 1960 were 35 years of age and older ����?? including men and women, black and white. A unique feature of this cohort is the fact that 102 high socio-economic status (SES) black men were purposefully included. The primary hypothesis of the original study was to investigate racial differences in the manifestation and risk factors for coronary disease. Over the ensuing 40+ years, a variety of outcome measurements were incorporated into the re-examination of the participants, including psychosocial, behavioral, aging and functional measures. Subjects were initially interviewed and examined in 1960 and 1963. Subsequent interviews and examinations took place during the following time periods: 1974-1975, 1984-1985, 1987-1989, and 1990-1991. During the most recent questionnaire (1990-1991), the following topics were examined: general health, smoking, functional disability, physical disability, cardiovascular health, sexual dysfunction, cognitive disability, depression, coffee consumption, medication history, medical history, nutrition, and body image. In addition, serum samples and blood pressure measurements were taken, and a physical exam was performed by a physician. A search of the National Death Index was completed through the year 2000, matching individuals with date and cause of death. Vital status of the CHS study participants through 12-31-2000 is presented below. Dead * White Men 539 (82.5%) * White Women 500 (67.5%) * Black Men 281 (84.4%) * High SES Black Men 59 (57.8%) * Black Women 343 (75.6%) Data Availability: Datasets are stored in the National Archive of Computerized Data on Aging (NACDA) in the ICPSR as Study No. 4050. Data are also available from the Medical University of South Carolina Library; contact a PI, Paul J. Nietert, nieterpj (at) musc.edu for further information. * Dates of Study: 1960-2000 * Study Features: Longitudinal, Minority Oversamples, Anthropometric Measures * Sample Size: 1960: 2,283 (baseline) Link ICPSR, http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/04050

Proper citation: Charleston Heart Study (RRID:SCR_008895) Copy   

•   Source: SciCrunch Registry

http://www.gazel.inserm.fr/

A 20 year, 20,000 person, open longitudinal epidemiological study of a cohort town. GAZEL was not constructed to answer a specific question rather it was designed to help analyze a wide range of scientific problems and is accessible to the community of researchers specializing in epidemiology. Translation is not available for all pages. The GAZEL cohort, set up in 1989 by Inserm Unit 88 (subsequently Unit 687), in cooperation with several departments of ��lectricit�� de France-Gaz de France (EDF-GDF), was a public utility firm in France involved in production, transmission and distribution of energy. GAZEL initially included 20 624 volunteers working at EDF-GDF (15 010 men and 5614 women), aged from 35 to 50 years. In accordance with its purpose as a scientific research platform, the GAZEL cohort is permanently open to epidemiologic research teams. Today, more than 50 projects on very diversified themes have been set up in GAZEL by some 20 teams, French, belonging to different bodies, and foreign (Germany, Belgium, Canada, Great Britain, Sweden, Finland, and USA).

Proper citation: Gazel Database (RRID:SCR_008962) Copy   

•   Source: SciCrunch Registry

http://blog.clearscience.io/

THIS RESOURCE IS NO LONGER IN SERVICE, documented July 27, 2015. Infrastructure for more effective scientific communication by leveraging the open APIs of GitHub, Amazon Web Services, and Synapse, clearScience demonstrates how scientists can easily transition from exploring dataexecuting scienceand providing the scientific community all the resources and artifacts to recreate analyses. By capturing the complete lifecycle of a project, reproducibility becomes a byproduct rather than a burden of publication. Further, we provide for forking an analysis, allowing anyone to explore and elaborate on "published" work. If the goal of biomedical research is to deliver results that will ultimately alleviate suffering and minimize harm to patients, being able to transparently share, reproduce, and build off of one another's work is critical to scientific progress. clearScience represents one compelling model for facilitating this progress.

Proper citation: clearScience (RRID:SCR_008958) Copy   

•   Source: SciCrunch Registry

http://genomics.senescence.info/genes/

Collection of annotated and manually curated data of genes related to aging divided into genes related to longevity and/or aging in model organisms (yeast, worms, flies, mice, etc.) and aging related human genes.

Proper citation: GenAge (RRID:SCR_010223) Copy   

•   Source: SciCrunch Registry

http://mitointeractome.kobic.kr/

Database that gathers data on interactions in the mitochondrial proteome that has been used to construct a network for the aging process in humans and to identify interactions that influence this process, since mitochondria is a major source of cellular reactive oxygen species that accumulate during aging. It will: # aid in increasing our understanding of the molecular functions and interaction networks of mitochondrial proteins, # help in identifying new target proteins for experimental research using predicted protein-protein interaction information, and # help in identifying biomarkers for diagnosis and new molecular targets for drug development related to mitochondria. How is MitoInteractome different? * Provides protein-protein interaction information with graphical display. * Applies newly added new mitochondrial protein information by using BLAST incorporated in Mitointeractome * Shows correlation of mutation with their impact * Provides specific pathway information to aid study of their impact * Contains SNP Information

Proper citation: MitoInteractome (RRID:SCR_010225) Copy   

•   Source: SciCrunch Registry

http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000674.v1.p1

Human genetics data from an immense (78,000) and ethnically diverse population available for secondary analysis to qualified researchers through the database of Genotypes and Phenotypes (dbGaP). It offers the opportunity to identify potential genetic risks and influences on a broad range of health conditions, particularly those related to aging. The GERA cohort is part of the Research Program on Genes, Environment, and Health (RPGEH), which includes more than 430,000 adult members of the Kaiser Permanente Northern California system. Data from this larger cohort include electronic medical records, behavioral and demographic information from surveys, and saliva samples from 200,000 participants obtained with informed consent for genomic and other analyses. The RPGEH database was made possible largely through early support from the Robert Wood Johnson Foundation to accelerate such health research. The genetic information in the GERA cohort translates into more than 55 billion bits of genetic data. Using newly developed techniques, the researchers conducted genome-wide scans to rapidly identify single nucleotide polymorphisms (SNPs) in the genomes of the people in the GERA cohort. These data will form the basis of genome-wide association studies (GWAS) that can look at hundreds of thousands to millions of SNPs at the same time. The RPGEH then combined the genetic data with information derived from Kaiser Permanente''s comprehensive longitudinal electronic medical records, as well as extensive survey data on participants'' health habits and backgrounds, providing researchers with an unparalleled research resource. As information is added to the Kaiser-UCSF database, the dbGaP database will also be updated.

Proper citation: Resource for Genetic Epidemiology Research on Adult Health and Aging (RRID:SCR_010472) Copy   

•   Source: SciCrunch Registry

http://www.nia.nih.gov/research/dab/aged-rodent-tissue-bank-handbook

A repository of tissue collected from the NIA Aged Rodent Colonies under contractual arrangement with BioReliance. The NIA colonies are barrier maintained and Specific Pathogen Free. Tissues are fresh frozen and stored at -80 degrees Celsius. Tissue from the NIA Aged Rodent Tissue Bank is available to investigators at academic and nonprofit research institutions who are engaged in funded research on aging. The project name and source of funding must accompany all orders. It may not be possible to ship tissue to foreign countries that have restrictions on the import of animal tissues or products. Please Note: Incomplete order forms will be returned. We can only offer following week delivery for those orders for which completed order forms are received by the deadline of Tuesday noon, Eastern time. Starting April 1, 2012, a copy (.pdf) of the purchase order must be emailed along with the order form.

Proper citation: Aged Rodent Tissue Bank (RRID:SCR_010607) Copy   

•   Source: SciCrunch Registry

http://www.nia.nih.gov/research/blog

Blog intended for grantees of the National Institute on Aging (NIA) at the NIH, as well as applicants for funding, those with an application in mind, application reviewers, and students pursuing careers in research on aging and Alzheimer's disease.

Proper citation: Inside NIA: A Blog for Researchers (RRID:SCR_012812) Copy   

•   Source: SciCrunch Registry

http://www.seattle.eric.research.va.gov/VETR/Home.asp

The Vietnam Era Twin (VET) Registry is a closed cohort composed of approximately 7,000 middle-aged male-male twin pairs both of whom served in the military during the time of the Vietnam conflict (1964-1975). The Registry is a United States Department of Veterans Affairs (VA) resource that was originally constructed from military records; the Registry has been in existence for almost 20 years. It is one of the largest national twin registries in the US and currently has members living in all 50 states. Initially formed to address questions about the long-term health effects of service in Vietnam, the Registry has evolved into a resource for genetic epidemiological studies of mental and physical health conditions. Several waves of mail and telephone surveys have collected a wealth of health-related information on Registry twins, referred to as members. In addition to twins, selected adult offspring of twins and the mothers of those offspring are also VET Registry members. More recent data collection efforts have focused on specific sets of twin pairs and have conducted detailed clinical or laboratory testing. Selected Vietnam Era Registry Research Studies: * Veteran Health Study * VETSA 2: A Longitudinal Study of Cognitive Aging * Alcoholism Course thought Midlife: A Twin Family Study and Offspring of Twins: G, E and GxE Risk for Alcoholism * GE: Offspring of Twins with Substance Use Disorder * Mechanisms Linking Depression to Cardiovascular Risk (Twins Heart Study 2) * Post-traumatic Stress Disorder and Cardiovascular Disease * Biological Markers for Post-traumatic Stress Disorder (T3) * Memory and the Hippocampus in Vietnam-era Twins with PTSD (Time 3)

Proper citation: Vietnam Era Twin Registry (RRID:SCR_008807) Copy   

•   Source: SciCrunch Registry