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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
WebGestalt: WEB-based GEne SeT AnaLysis Toolkit
 
Resource Report
Resource Website
1000+ mentions
WebGestalt: WEB-based GEne SeT AnaLysis Toolkit (RRID:SCR_006786) WebGestalt data access protocol, web application, web service, software resource Web based gene set analysis toolkit designed for functional genomic, proteomic, and large-scale genetic studies from which large number of gene lists (e.g. differentially expressed gene sets, co-expressed gene sets etc) are continuously generated. WebGestalt incorporates information from different public resources and provides a way for biologists to make sense out of gene lists. This version of WebGestalt supports eight organisms, including human, mouse, rat, worm, fly, yeast, dog, and zebrafish. proteomic, gene expression, genome wide association study, statistical analysis, functional genomics, protein protein interaction, pathway, regulatory module, analysis toolkit, web application is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: Entrez Gene
is related to: KEGG
is related to: Pathway Commons
is related to: WikiPathways
is related to: PheWAS Catalog
is related to: webgestaltr
has parent organization: Vanderbilt University; Tennessee; USA
NIAAA U01 AA016662;
NIAAA U01 AA013512;
NIDA P01 DA015027;
NIMH P50 MH078028;
NIMH P50 MH096972;
NCI U24 CA159988;
NIGMS R01 GM088822
PMID:24233776
PMID:15980575
PMID:14975175
Free, Freely available OMICS_02222, nif-0000-30622 http://bioinfo.vanderbilt.edu/webgestalt/ SCR_006786 GOTM, Gene Ontology Tree Machine, WebGestalt2, WEB-based GEne SeT AnaLysis Toolkit, WebGestalt 2026-02-17 10:01:09 2760
YeTFaSCo
 
Resource Report
Resource Website
10+ mentions
YeTFaSCo (RRID:SCR_006893) YeTFaSCo storage service resource, data or information resource, production service resource, analysis service resource, database, service resource, data analysis service, data repository Collection of all available transcription factor (TF) specificities for the yeast Saccharomyces cerevisiae in Position Frequency Matrix (PFM) or Position Weight Matrix (PWM) formats. The specificities are evaluated for quality using several metrics. With this website, you can scan sequences with the motifs to find where potential binding sites lie, inspect precomputed genome-wide binding sites, find which TFs have similar motifs to one you have found, and download the collection of motifs. Submissions are welcome. transcription factor, binding site, sequence, yeast, motif, gene, genome, protein, protein complex is listed by: OMICtools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
Ontario Graduate Scholarship awards ;
Canadian Institutes of Health Research Operating Grant MOP-490425;
Canadian Institutes of Health Research Operating Grant MOP-86705
PMID:22102575 Acknowledgement requested nlx_151611, OMICS_01861 SCR_006893 Yeast Transcription Factor Specificity Compendium, YeTFaSCo: The Yeast Transcription Factor Specificity Compendium 2026-02-17 10:01:08 34
g:Profiler
 
Resource Report
Resource Website
1000+ mentions
g:Profiler (RRID:SCR_006809) data access protocol, production service resource, analysis service resource, service resource, software resource, web service, data analysis service Web server for functional enrichment analysis and conversions of gene lists. Web based tool for functional profiling of gene lists from large scale experiments. Has web interface with powerful visualization. Used for analyzing data from any organism. gene, high-throughput, genomics, visualization, statistical analysis, slimmer-type tool, term enrichment, protein interaction, functional similarity, analysis, coexpression, gene id, network enrichment analysis, orthology mapping, genomic locus, ontology or annotation visualization, other analysis, ortholog, functional profile, gene list, ontology, pathway, transcription factor, microrna, regulatory motif, protein-protein interaction, biomolecule, gene expression, gene, homology, single nucleotide polymorphism, dna polymorphism, chromosome, network analysis, disease gene, r is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: Ensembl
is related to: Ensembl Genomes
has parent organization: BIIT - Bioinformatics Algorithmics and Data Mining Group
works with: gProfiler2
Estonian Research Council grants ;
European Regional Development Fund for CoE of Estonian ICT research EXCITE projects
PMID:21646343
PMID:17478515
PMID:31066453
Free, Freely available OMICS_02223, nif-0000-31975 SCR_006809 G:Profiler, g:profiler, gProfiler 2026-02-17 10:00:59 2078
GOdist
 
Resource Report
Resource Website
GOdist (RRID:SCR_005770) GOdist data analysis software, software application, data processing software, software resource GOdist is a Matlab program that analyzes Affymetrix microarray expression data implementing Kolmogorov-Smirnov (KS) continuous statistics approach. It also implements the discrete approach using Fisher exact test employing a two-tailed hypergeometric distribution. GOdist enables detection of both kinds of changes within specific GO terms represented on the array in relation to different populations: the global array population, the direct parents of the analyzed GO term and the global parent of it (e.g. biological process, molecular function or cellular component). Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible statistical analysis, function, gene, gene expression, gene ontology, matlab, affymetrix, microarray, biological process, molecular function, cellular component, fisher exact test, kolmogorov-smirnov is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Hebrew University of Jerusalem; Jerusalem; Israel
PMID:15550480 Free for academic use nlx_149260 SCR_005770 2026-02-17 10:00:48 0
Ontologizer
 
Resource Report
Resource Website
100+ mentions
Ontologizer (RRID:SCR_005801) Ontologizer software application, production service resource, data processing software, analysis service resource, source code, service resource, software resource, data analysis service The Ontologizer is a Java webstart application for GO term enrichment analysis that provides browsing and graph visualization capabilities. The Ontologizer allows users to analyze data with the standard Fisher exact test and also the parent-child method and topology methods. The tool can be started directly from the web using Java webstart. For graph visualizations, users need to install the GraphViz library. The tool is freely available to all, and source code is available at SourceForge. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible high-throughput, biological data, gene ontology, statistical analysis, fisher exact test, visualization, graph, java, annotation, parent-child, topology is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Charite - Universitatsmedizin Berlin; Berlin; Germany
DFG SFB 760 PMID:18511468
PMID:17848398
Free for academic use nlx_149289 SCR_005801 The Ontologizer 2026-02-17 10:00:49 122
THEA - Tools for High-throughput Experiments Analysis
 
Resource Report
Resource Website
THEA - Tools for High-throughput Experiments Analysis (RRID:SCR_005802) THEA data analysis software, software application, data processing software, software resource THIS RESOURCE IS NO LONGER IN SERVICE, on documented July 16, 2012. An integrated information processing system dedicated to the analysis of post-genomic data. It allows automatic annotation of data issued from classification systems with selected biological information (including the Gene Ontology). Users can either manually search and browse through these annotations, or automatically generate meaningful generalizations according to statistical criteria (data mining). Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible high-throughput, analysis, ontology, microarray, genomic, annotation, gene ontology, data mining, statistical analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Virtual Biology Lab
French Ministry of Higher Education and Research ;
Bioinformatic Program
PMID:15130932 THIS RESOURCE IS NO LONGER IN SERVICE nlx_149290 SCR_005802 Tools for High-throughput Experiments Analysis 2026-02-17 10:00:57 0
CGAP GO Browser
 
Resource Report
Resource Website
1+ mentions
CGAP GO Browser (RRID:SCR_005676) CGAP GO Browser data or information resource, service resource, data set With the CGAP GO browser, you can browse through the GO vocabularies, and find human and mouse genes assigned to each term. GO data updated every few months. Platform: Online tool gene, biological process, cellular component, molecular function, browser, ontology, ontology or annotation browser is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Cancer Genome Anatomy Project
NCI Free for academic use nlx_149116 SCR_005676 Cancer Genome Anatomy Project GO Browser 2026-02-17 10:00:57 4
PubSearch
 
Resource Report
Resource Website
1+ mentions
PubSearch (RRID:SCR_005830) PubSearch data or information resource, service resource, database, software resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. PubSearch is a web-based literature curation tool, allowing curators to search and annotate genes to keywords from articles. It has a simple mySQL database backend and uses a set of Java Servlets and JSPs for querying, modifying, and adding gene, gene-annotation, and literature information. PubSearch can be downloaded from GMOD. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene, annotate, editor, literature curation tool, literature, ontology or annotation editor is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: TAIR
has parent organization: Stanford University; Stanford; California
NHGRI R01HG02728 THIS RESOURCE IS NO LONGER IN SERVICE nlx_149338 SCR_005830 2026-02-17 10:01:01 1
Onto-Express
 
Resource Report
Resource Website
50+ mentions
Onto-Express (RRID:SCR_005670) OE data or information resource, production service resource, analysis service resource, database, service resource, data analysis service The typical result of a microarray experiment is a list of tens or hundreds of genes found to be differentially regulated in the condition under study. Independently of the methods used to select these genes, the common task faced by any researcher is to translate these lists of genes into a better understanding of the biological phenomena involved. Currently, this is done through a tedious combination of searches through the literature and a number of public databases. We developed Onto-Express (OE) as a novel tool able to automatically translate such lists of differentially regulated genes into functional profiles characterizing the impact of the condition studied. OE constructs functional profiles (using Gene Ontology terms) for the following categories: biochemical function, biological process, cellular role, cellular component, molecular function and chromosome location. Statistical significance values are calculated for each category. We demonstrated the validity and the utility of this comprehensive global analysis of gene function by analyzing two breast cancer data sets from two separate laboratories. OE was able to identify correctly all biological processes postulated by the original authors, as well as discover novel relevant mechanisms (Draghici et.al, Genomics, 81(2), 2003). Other results obtained with Onto-Express can be found in Khatri et.al., Genomics. 79(2), 2002. Custom level of abstraction of the Gene Ontology. User account required. Platform: Online tool microarray, gene, ontology, gene expression, biochemical function, biological process, cellular role, cellular component, molecular function, chromosome location, java, data-mining, browser, visualization, analysis, statistical analysis, term enrichment, search engine, other analysis, ontology or annotation browser, ontology or annotation search engine, ontology or annotation visualization, database or data warehouse, custom level of abstraction of the gene ontology, FASEB list is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Wayne State University; Michigan; USA
Wayne State University School of Medicine; Michigan; USA ;
NICHD HD36512
PMID:12620386
PMID:11829497
PMID:15215428
Free for academic use nlx_149110 http://vortex.cs.wayne.edu:8080 SCR_005670 Onto-Express (OE) 2026-02-17 10:00:47 85
MAPPFinder
 
Resource Report
Resource Website
10+ mentions
MAPPFinder (RRID:SCR_005791) MAPPFinder data analysis software, software application, data processing software, software resource MAPPFinder is an accessory program for GenMAPP. This program allows users to query any existing GenMAPP Expression Dataset Criterion against GO gene associations and GenMAPP MAPPs (microarray pathway profiles). The resulting analysis provides the user with results that can be viewed directly upon the Gene Ontology hierarchy and within GenMAPP, by selecting terms or MAPPs of interest. Platform: Windows compatible gene, gene ontology, gene association, gene expression, profile, microarray, pathway, statistical analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of California at San Francisco; California; USA
has parent organization: Gene Map Annotator and Pathway Profiler
University of California at San Francisco; California; USA ;
San Francisco General Hospital; California; USA ;
NHLBI ;
NCRR MO1RR00083
PMID:12540299 Free for academic use nlx_149270 SCR_005791 2026-02-17 10:00:48 26
GeneTools
 
Resource Report
Resource Website
1000+ mentions
GeneTools (RRID:SCR_005663) GeneTools data or information resource, data access protocol, web service, software resource Web-service providing access to database that brings together information from broad range of resources. Web application for functional annotation and statistical hypothesis testing. Provides tools for analysis of genomic and microarray data. Collection of tools include Bibliographic Information,Databases,Gene Annotation,Gene Regulation, Microarray,Proteins,Sequence Manipulation - Nucleic Acids,Sequence Manipulation - Protein, Systems Biology. genome-wide analyses, annotation, gene, visualization, ontology or annotation browser, ontology or annotation search engine, ontology or annotation visualization, database or data warehouse, statistical analysis, term enrichment, browser, search engine, FASEB list is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Norwegian University of Science and Technology; Trondheim; Norway
is parent organization of: GeneTools: explore GeneOntology
National Council on Cardiovascular Diseases ;
Norwegian University of Science and Technology ;
Norwegian Research Council
PMID:17062145 SCR_002911, SCR_007388, nif-0000-00407, nif-0000-30011, nlx_149102 SCR_005663 2026-02-17 10:00:36 1752
GOArray
 
Resource Report
Resource Website
1+ mentions
GOArray (RRID:SCR_005785) GOArray data analysis software, software application, data processing software, software resource GOArray is a Perl program which inputs a lists of genes annotated as of interest (GOI) or not, and determines if any associated GO terms have an overrepresentation of GOI. A permutation test is optionally used to assess confidence in the results. Output includes multiple visualizations and supplementary information and, for future reference, a summary of the statistical methods used. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible perl, gene, visualization, gene ontology, statistical analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Yale School of Medicine; Connecticut; USA
Free for academic use nlx_149259 http://goarray.med.yale.edu/GOArray/ SCR_005785 2026-02-17 10:01:00 1
GeneInfoViz
 
Resource Report
Resource Website
GeneInfoViz (RRID:SCR_005680) GeneInfoViz data or information resource, production service resource, analysis service resource, database, service resource, data analysis service GeneInfoViz is a web based tool for batch retrieval of gene function information, visualization of GO structure and construction of gene relation networks. It takes a input list of genes in the form of LocusLink ID, UniGeneID, gene symbol, or accession number and returns their functional genomic information. Based on the GO annotations of the given genes, GeneInfoViz allows users to visualize these genes in the DAG structure of GO, and construct a gene relation network at a selected level of the DAG. Platform: Online tool gene network, gene ontology, visualization, gene, ontology or annotation browser is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Tennessee Health Science Center; Tennessee; USA
PMID:15724283 Free for academic use nlx_149121 SCR_005680 GeneInfoViz: Constructing and Visualizing Gene Relation Networks 2026-02-17 10:00:56 0
TrED
 
Resource Report
Resource Website
1+ mentions
TrED (RRID:SCR_005869) TrED software application, data or information resource, data processing software, data analysis software, database, software resource TrED is a database of Trichophyton rubrum, a fungus. The database contains strains, cDNA libraries, pathways, and microarray data as well as a directed set of literature. Trichophyton rubrum is the most common dermatophyte species and the most frequent cause of fungal skin infections in humans worldwide. It''''s a major concern because feet and nail infections caused by this organism is extremely difficult to cure. A large set of expression data including expressed sequence tags (ESTs) and transcriptional profiles of this important fungal pathogen are now available. Careful analysis of these data can give valuable information about potential virulence factors, antigens and novel metabolic pathways. We intend to create an integrated database TrED to facilitate the study of dermatophytes, and enhance the development of effective diagnostic and treatment strategies. All publicly available ESTs and expression profiles of T. rubrum during conidial germination in time-course experiments and challenged with antifungal agents are deposited in the database. In addition, comparative genomics hybridization results of 22 dermatophytic fungi strains from three genera, Trichophyton, Microsporum and Epidermophyton, are also included. ESTs are clustered and assembled to elongate the sequence length and abate redundancy. TrED provides functional analysis based on GenBank, Pfam, and KOG databases, along with KEGG pathway and GO vocabulary. It is integrated with a suite of custom web-based tools that facilitate querying and retrieving various EST properties, visualization and comparison of transcriptional profiles, and sequence-similarity searching by BLAST. TrED is built upon a relational database, with a web interface offering analytic functions, to provide integrated access to various expression data of T. rubrum and comparative results of dermatophytes. It is devoted to be a comprehensive resource and platform to assist functional genomic studies in dermatophytes. expressed sequence tag, transcriptional profile, fungal pathogen, bmu01672, chuv862.00, mya-3108, cdna, pathway, microarray, classification, blast, unisequence, peptide, annotation is related to: Gene Ontology
is related to: KEGG
is related to: GenBank
is related to: Pfam
Ministry of Science and Technology of China 2006AA020504 PMID:17650345 nlx_149408 SCR_005869 TrED - T. rubrum Expression Database, Trichophyton rubrum Expression Database, Trichophyton rubrum Expression Database (TrED) 2026-02-17 10:00:49 5
EGAN: Exploratory Gene Association Networks
 
Resource Report
Resource Website
1+ mentions
EGAN: Exploratory Gene Association Networks (RRID:SCR_008856) EGAN data analysis software, software application, data processing software, software resource Exploratory Gene Association Networks (EGAN) is a software tool that allows a bench biologist to visualize and interpret the results of high-throughput exploratory assays in an interactive hypergraph of genes, relationships (protein-protein interactions, literature co-occurrence, etc.) and meta-data (annotation, signaling pathways, etc.). EGAN provides comprehensive, automated calculation of meta-data coincidence (over-representation, enrichment) for user- and assay-defined gene lists, and provides direct links to web resources and literature (NCBI Entrez Gene, PubMed, KEGG, Gene Ontology, iHOP, Google, etc.). EGAN functions as a module for exploratory investigation of analysis results from multiple high-throughput assay technologies, including but not limited to: * Transcriptomics via expression microarrays or RNA-Seq * Genomics via SNP GWAS or array CGH * Proteomics via MS/MS peptide identifications * Epigenomics via DNA methylation, ChIP-on-Chip or ChIP-Seq * In-silico analysis of sequences or literature EGAN has been built using Cytoscape libraries for graph visualization and layout, and is comparable to DAVID, GSEA, Ingenuity IPA and Ariadne Pathway Studio. There are pre-collated EGAN networks available for human (Homo sapiens), mouse (Mus musculus), rat (Rattus norvegicus), chicken (Gallus gallus), zebrafish (Danio rerio), fruit fly (Drosophila melanogaster), nematode (Caenorhabditis elegans), mouse-ear cress (Arabidopsis thaliana), rice (Oryza sativa) and brewer's yeast (Saccharomyces cerevisiae). There is now an EGAN module available for GenePattern (human-only). Platform: Windows compatible, Mac OS X compatible, Linux compatible gene, gene association, network, protein-protein interaction, pathway, interaction, annotation, signaling pathway, enrichment, cytoscape, visualization is listed by: 3DVC
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: Cytoscape
has parent organization: UCSF Helen Diller Family Comprehensive Cancer Center Biostatistics Core
NCI P30 CA92103 PMID:19933825 Free for academic use nlx_149222 SCR_008856 Exploratory Gene Association Networks, Exploratory Gene Association Networks (EGAN) 2026-02-17 10:01:25 8
AgingDB
 
Resource Report
Resource Website
AgingDB (RRID:SCR_010226) AgingDB storage service resource, data or information resource, database, service resource, data repository A database that stores information on the biomolecules which are modulated during aging and by caloric restriction (CR). To enhance its usefulness, data collected from studies of CR''''s anti-oxidative action on gene expression, oxidative stress, and many chronic age-related diseases are included. AgingDB is organized into two sections A) apoptosis and the various mitochondrial biomolecules that play a role in aging; B) nuclear transcription factors known to be_sensitive to oxidative environment. AgingDB features an imagemap of biomolecular signal pathways and visualized information that includes protein-protein interactions of biomolecules. Authorized users can submit a new biomolecule or edit an existing biomolecule to reflect latest developments. oxidative stress, calorie restriction, pathway, biomolecule, signal pathway, interaction, gene, protein, protein-protein interaction, apoptosis, mitochondrial, nuclear transcription factor is related to: Gene Ontology
has parent organization: Pusan National University; Busan; South Korea
Aging PMID:23604914 The community can contribute to this resource nlx_156773 http://aging.pharm.pusan.ac.kr/AgingDB/ SCR_010226 Aging Database, Aging DB 2026-02-17 10:01:43 0
Gene Ontology Extension
 
Resource Report
Resource Website
Gene Ontology Extension (RRID:SCR_010327) GO-EXT data or information resource, ontology, controlled vocabulary An extension of the Gene Ontology. obo is listed by: BioPortal
has parent organization: Gene Ontology
nlx_157414 SCR_010327 2026-02-17 10:01:27 0
Centre for Modeling Human Disease Gene Trap Resource
 
Resource Report
Resource Website
1+ mentions
Centre for Modeling Human Disease Gene Trap Resource (RRID:SCR_002785) CMHD Gene Trap Resource material service resource, production service resource, service resource, biomaterial manufacture Generate gene trap insertions using mutagenic polyA trap vectors, followed by sequence tagging to develop a library of mutagenized ES cells freely available to the scientific community. This library is searchable by sequence or key word searches including gene name or symbol, chromosome location, or Gene Ontology (GO) terms. In addition,they offer a custom email alert service in which researchers are able to submit search criteria. Researchers will receive automated e-mail notification of matching gene trap clones as they are entered into the library and database. The resource features the use of complementary second and third generation polyA trap vectors developed by the Stanford lab and the laboratory of Professor Yasumasa Ishida of the Nara Institute of Science and Technology (NAIST) in Japan to mutagenize murine embryonic stem (ES) cells. CMHD gene trap clones are distributed by the Canadian Mouse Mutant Repository(CMMR). Information about ordering, services, and pricing can be found on their web site (http://www.cmmr.ca/services/index.html)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026. embryonic stem cell, polya trap vector, gene trap, insertion, mutagenic polya trap vector, sequence, expression, mutagenesis, gene, mutation, expression profile, phenotype, database, gene expression, vector insertion, expressed sequence tag, blast, clone is related to: Gene Ontology
is related to: CMMR - Canadian Mouse Mutant Repository
is related to: International Gene Trap Consortium
has parent organization: CMHD - Centre for Modeling Human Disease
Canadian Institutes of Health Research ;
Genome Canada ;
Genome Prairie ;
NIH
PMID:14681480 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02891 http://www.cmhd.ca/sub/genetrap.asp SCR_002785 Centre for Modeling Human Disease (CMHD) Gene Trap Resource 2026-02-17 09:59:58 3
BioPortal
 
Resource Report
Resource Website
100+ mentions
BioPortal (RRID:SCR_002713) BioPortal ontology, repository, storage service resource, data or information resource, controlled vocabulary, service resource, data repository Open repository of biomedical ontologies that provides access via Web browsers and Web services to ontologies. It supports ontologies in OBO format, OWL, RDF, Rich Release Format (RRF), Protege frames, and LexGrid XML. Functionality includes the ability to browse, search and visualize ontologies as well as to comment on, and create mappings for ontologies. Any registered user can submit an ontology. The NCBO Annotator and NCBO Resource Index can also be accessed via BioPortal. Additional features: * Add Reviews: rate the ontology according to several criteria and describe your experience using the ontology. * Add Mappings: submit point-to-point mappings or upload bulk mappings created with external tools. Notification of new Mappings is RSS-enabled and Mappings can be browsed via BioPortal and accessed via Web services. * NCBO Annotator: Tool that tags free text with ontology terms. NCBO uses the Annotator to generate ontology annotations, creating an ontology index of these resources accessible via the NCBO Resource Index. The Annotator can be accessed through BioPortal or directly as a Web service. The annotation workflow is based on syntactic concept recognition (using the preferred name and synonyms for terms) and on a set of semantic expansion algorithms that leverage the ontology structure (e.g., is_a relations). * NCBO Resource Index: The NCBO Resource Index is a system for ontology based annotation and indexing of biomedical data; the key functionality of this system is to enable users to locate biomedical data linked via ontology terms. A set of annotations is generated automatically, using the NCBO Annotator, and presented in BioPortal. This service uses a concept recognizer (developed by the National Center for Integrative Biomedical Informatics, University of Michigan) to produce a set of annotations and expand them using ontology is_a relations. * Web services: Documentation on all Web services and example code is available at: BioPortal Web services. biomedical, thesaurus, ontology mapping, annotation, metadata standard, ontology repository, portal, web service, obo, owl, rdf, rrf protege frame, lexgrid xml lists: MeGO
lists: Porifera Ontology
lists: EnvO
lists: Research Network and Patient Registry Inventory Ontology
lists: Semantic DICOM Ontology
lists: Time Event Ontology
lists: Variation Ontology
lists: Vertebrate Skeletal Anatomy Ontology
lists: Epoch Clinical Trial Ontology
lists: Gazetteer
lists: Human Disease Ontology
lists: Information Artifact Ontology
lists: NCBITaxon
lists: Amphibian Taxonomy Ontology
lists: Anatomic Pathology Lexicon
lists: HIV ontology
lists: International Classification of Primary Care - 2 PLUS
lists: Mathematical Modelling Ontology
lists: Nursing Interventions Classification
lists: Phylogenetic Ontology
lists: Bleeding History Phenotype Ontology
lists: Body System Terms from ICD11
lists: Synthetic Biology Open Language Visual Ontology
lists: Teleost Anatomy Ontology
lists: Teleost Taxonomy Ontology
lists: ECO
lists: Bioassay Ontology
lists: RightField
lists: Gene Ontology
lists: HGNC
lists: Interaction Ontology
lists: International Classification for Nursing Practice
lists: Spider Ontology
lists: Vertebrate Trait Ontology
lists: Mental Functioning Ontology
lists: Ascomycete Phenotype Ontology
lists: Beta Cell Genomics Ontology
lists: Biological Collections Ontology
lists: Chemical Methods Ontology
lists: Chemical Information Ontology
lists: Common Anatomy Reference Ontology
lists: Experimental Conditions Ontology
lists: Dictyostelium Discoideum Anatomy Ontology
lists: Fission Yeast Phenotype Ontology
lists: Fly Taxonomy
lists: FlyBase Controlled Vocabulary
lists: Hymenoptera Anatomy Ontology
lists: Influenza Ontology
lists: Lipid Ontology
lists: Kinetic Simulation Algorithm Ontology
lists: Malaria Ontology
lists: FMA
lists: Minimal Anatomical Terminology
lists: NEMO Ontology
lists: Ontology for Genetic Interval
lists: Ontology for Parasite LifeCycle
lists: Ontology of Adverse Events
lists: Ontology of Medically Related Social Entities
lists: Ontology of Vaccine Adverse Events
lists: Rat Strain Ontology
lists: Plant Environmental Conditions
lists: Plant Trait Ontology
lists: Population and Community Ontology
lists: RNA Ontology
lists: Rat Strain Ontology
lists: Subcellular Anatomy Ontology
lists: Software Ontology
lists: Suggested Ontology for Pharmacogenomics
lists: Vertebrate Taxonomy Ontology
lists: PharmGKB Ontology
lists: Physico-Chemical Process
lists: International Classification for Patient Safety
lists: Adverse Event Reporting Ontology
lists: Experimental Factor Ontology
lists: Mass Spectrometry Ontology
lists: Master Drug Data Base Clinical Drugs
lists: Medaka Fish Anatomy and Development Ontology
lists: Medical Diagnostic Categories - Diagnosis Related Groups
lists: Medical Dictionary for Regulatory Activities
lists: Minimal Standard Terminology of Digestive Endoscopy
lists: Minimal Standard Terminology of Digestive Endoscopy - French
lists: Ontology of Physical Exercises
lists: Mosquito Gross Anatomy Ontology
lists: Systematized Nomenclature of Medicine - International Version
lists: Mosquito Insecticide Resistance Ontology
lists: Mouse Experimental Design Ontology
lists: Mouse Gross Anatomy and Development Ontology
lists: Systematized Nomenclature of Medicine - Clinical Terms
lists: Systems Chemical Biology and Chemogenomics Ontology
lists: Mouse Pathology Ontology
lists: NIF Cell Ontology
lists: NHS Quality Indicators
lists: Neural-Immune Gene Ontology
lists: Ontology of Physics for Biology
lists: Cell Type Ontology
lists: Xenopus Anatomy Ontology
lists: SO
lists: Ontology of Pneumology
lists: Open Biological and Biomedical Ontologies Relationship Types
lists: Biomedical Resource Ontology
lists: MGED Ontology
lists: Pharmacovigilance Ontology
lists: PhenX Phenotypic Terms
lists: Bioinformatics Web Service Ontology
lists: SysMO JERM Ontology of Systems Biology for Micro-Organisms
lists: MeSH
lists: PATO
lists: BFO
lists: MPO
lists: PR
lists: Cereal Plant Development Ontology
lists: PhenomeBLAST Ontology
lists: VIVO
lists: Computer Assisted Brain Injury Rehabilitation Ontology
lists: Computer Retrieval of Information on Scientific Projects Thesaurus
lists: NIFSTD
lists: Cell Line Ontology
lists: Student Health Record Ontology
lists: Zebrafish Anatomical Ontology
lists: Physical Medicine and Rehabilitation
lists: Randomized Controlled Trials Ontology
lists: Human Phenotype Ontology
lists: Read Codes Clinical Terms Version 3
lists: Reference Sequence Annotation
lists: Regulation of Gene Expression Ontolology
lists: Neurobehavior Ontology
lists: Regulation of Transcription Ontology
lists: Reproductive Trait and Phenotype Ontology
lists: Skin Physiology Ontology
lists: Vaccine Ontology
lists: OMIM
lists: MedlinePlus
lists: Adult Mouse Anatomy Ontology
lists: Bone Dysplasia Ontology
lists: Bone and Cartilage Tissue Engineering Ontology
lists: Botryllus schlosseri anatomy and development ontology
lists: EDAM Ontology
lists: LexGrid
lists: RxNorm
lists: Breast Cancer Grading Ontology
lists: Breast Tissue Cell Lines Ontology
lists: SBO
lists: Resource of Asian Primary Immunodeficiency Diseases Phenotype Ontology
lists: Brucellosis Ontology
lists: Sleep Domain Ontology
lists: C. elegans Development Vocabulary
lists: Physician Data Query
lists: C. elegans Gross Anatomy Vocabulary
lists: Plant Ontology
lists: C. elegans Phenotype Vocabulary
lists: CPTAC Proteomics Pipeline Infrastructure Ontology
lists: Cancer Research and Management ACGT Master Ontology
lists: Cancer Chemoprevention Ontology
lists: Cell Behavior Ontology
lists: Cereal Plant Gross Anatomy Ontology
lists: Cardiac Electrophysiology Ontology
lists: Cerebrotendinous Xanthomatosis Ontology
lists: Cell Cycle Ontology
lists: Cell Culture Ontology
lists: Cerrado concepts and plant community dynamics
lists: Clinical Signs and Symptoms Ontology
lists: Clusters of Orthologous Groups Analysis Ontology
lists: Computational Neuroscience Ontology
lists: BIRNLex
lists: Computer-Based Patient Record Ontology
lists: Congenital Heart Defects Ontology
lists: Drug Interaction Knowledge Base Ontology
lists: Healthcare Common Procedure Coding System
lists: Host Pathogen Interactions Ontology
lists: Human Dermatological Disease Ontology
lists: Solanaceae Phenotype Ontology
lists: Soy Ontology
lists: Spatial Ontology
lists: Surgical Secondary Events
lists: eagle-i research resource ontology
lists: Biological Pathways Exchange
lists: Autism Spectrum Disorder Phenotype Ontology
lists: BRENDA Tissue and Enzyme Source Ontology
lists: BioTop Ontology
lists: Family Health History Ontology
lists: International Classification of Diseases Version 9 - Clinical Modification
lists: BioModels Ontology
lists: Bilingual Ontology of Alzheimer
lists: BioPortal Metadata Ontology
lists: Biochemical Substructure Ontology
lists: Biodiversity Ontology
lists: Biological Imaging Methods Ontology
lists: International Classification of Functioning Disability and Health
lists: Biologie Hors Nomenclature
lists: International Classification of Primary Care
lists: Biomedical Research Integrated Domain Group Model
lists: KB Bio 101
lists: Bionutrition Ontology
lists: Artificial Intelligence Rheumatology Consultant System Ontology
lists: Leukocyte Surface Marker Ontology
lists: Cell Line Ontology by Mahadevan
lists: Cellular microscopy phenotype ontology
lists: ABA Adult Mouse Brain Ontology
lists: AEO
lists: African Traditional Medicine Ontology
lists: Alzheimer's disease ontology
lists: Amino Acid Ontology
lists: Amphibian Gross Anatomy Ontology
lists: Animal Natural History and Life History Ontology
lists: Coding Symbols for a Thesaurus of Adverse Reaction Terms
lists: Cognitive Atlas Ontology
lists: Common Terminology Criteria for Adverse Events
lists: Comparative Data Analysis Ontology
lists: Content Archive Resource Exchange Lexicon
lists: Crop Ontology
lists: Current Procedural Terminalogy Hierarchy
lists: Current Procedural Terminology
lists: DICOM Controlled Terminology
lists: Dataset processing
lists: Dengue Fever Ontology
lists: Dermatology Lexicon
lists: Diagnosis Ontology of Clinical Care Classification
lists: Diagnostic Ontology
lists: Disease core ontology applied to Rare Diseases
lists: Dispedia Core Ontology
lists: Drosophila Development Ontology
lists: Drosophila Gross Anatomy Ontology
lists: EDDA Study Design Terminology
lists: Electrocardiography Ontology
lists: Eligibility Feature Hierarchy
lists: Enzyme Mechanism Ontology
lists: Enzyme Reaction Ontology for partial chemical perspectives
lists: Epilepsy Ontology
lists: Loggerhead Nesting Ontology
lists: Fanconi Anemia Ontology
lists: Fire Ontology
lists: Flora Phenotype Ontology
lists: Fungal Gross Anatomy Ontology
lists: Human Developmental Anatomy Ontology abstract version 1
lists: G Protein-Coupled Receptor BioAssays Ontology
lists: Galen Ontology
lists: Gene Expression Ontology
lists: Gene Ontology Extension
lists: General Formal Ontology
lists: General Formal Ontology for Biology
lists: Genome Component Ontology
lists: Genomic Clinical Decision Support Ontology
lists: GeoSpecies Ontology
lists: Glycomics Ontology
lists: Habronattus Courtship Ontology
lists: Health Indicator Ontology
lists: Health Level Seven Reference Implementation Model Version 3
lists: Human Developmental Anatomy Ontology abstract version 2
lists: Human Developmental Anatomy Ontology timed version
lists: Human Interaction Network Ontology
lists: Human Physiology Simulation Ontology
lists: Logical Observation Identifier Names and Codes
lists: IMGT-ONTOLOGY
lists: Image and Data Quality Assessment Ontology
lists: Immune Disorder Ontology
lists: Infectious Disease Ontology
lists: InterNano Nanomanufacturing Taxonomy
lists: Interaction Network Ontology
lists: International Classification of External Causes of Injuries
lists: International Classification of Diseases Version 10
lists: International Classification of Diseases Version 10 - Clinical Modification
lists: International Classification of Diseases Version 10 - Procedure Coding System
lists: MR dataset acquisition
lists: Maize Gross Anatomy Ontology
lists: Major Histocompatibility Complex Ontology
lists: Medical image simulation
lists: Menelas Project Top-Level Ontology
lists: Mental State Assessment
lists: Metagenome Sample Vocabulary
lists: Metagenome and Microbes Environmental Ontology
lists: MicroRNA Ontology
lists: Microbial Culture Collection Vocabulary
lists: Microbial Typing Ontology
lists: Minimal Information about any Sequence Controlled Vocabularies
lists: Minimal Information about any Sequence Ontology
lists: NIF Dysfunction Ontlogy
lists: NIF Subcellular Ontology
lists: NMR-Instrument Component of Metabolomics Investigations Ontology
lists: Name Reaction Ontology
lists: NanoParticle Ontology
lists: National Cancer Institute Thesaurus
lists: National Drug Data File
lists: National Drug File - Reference Terminology
lists: Natural Products Ontology
lists: Neglected Tropical Disease Ontology
lists: Neomark Oral Cancer Ontology version 3
lists: Neomark Oral Cancer Ontology version 4
lists: Neural Motor Recovery Ontology
lists: NeuroMorpho.Org species ontology
lists: NeuroMorpho.Org species ontology old
lists: Non-Randomized Controlled Trials Ontology
lists: Nursing Care Coordination Ontology
lists: Ontological Knowledge Base Model for Cystic Fibrosis
lists: Ontology for Drug Discovery Investigations
lists: Ontology for General Medical Science
lists: Ontology for Genetic Disease Investigations
lists: Ontology for Genetic Susceptibility Factor
lists: Ontology for MicroRNA Target Prediction
lists: Symptom Ontology
lists: Ontology for Newborn Screening Follow-up and Translational Research
lists: Ontology of Alternative Medicine French
lists: Ontology of Biological and Clinical Statistics
lists: Ontology of Clinical Research
lists: Ontology of Core Data Mining Entities
lists: Ontology of Data Mining Investigations
lists: Pediatric Terminology
lists: Ontology of Experimental Variables and Values
lists: Ontology of General Purpose Datatypes
lists: Ontology of Geographical Region
lists: Ontology of Glucose Metabolism Disorder
lists: Ontology of Homology and Related Concepts in Biology
lists: Ontology of Language Disorder in Autism
lists: Orphanet Rare Disease Ontology
lists: Parasite Experiment Ontology
lists: Pathogen Transmission Ontology
lists: Pathogenic Disease Ontology
lists: Pharmacogenomic Relationships Ontology
lists: Physico-Chemical Methods and Properties
lists: Plant Anatomy
lists: Syndromic Surveillance Ontology
lists: Plant Structure Development Stage
lists: Portfolio Management Application
lists: Protein Modification Ontology
lists: Protein-Protein Interaction Ontology
lists: Proteomics Data and Process Provenance Ontology
lists: Provenance Ontology
lists: QUDT
lists: Quantitative Imaging Biomarker Ontology
lists: Radiology Lexicon
lists: Robert Hoehndorf Version of MeSH
lists: Role Ontology
lists: STATistics Ontology
lists: Sage Bionetworks Synapse Ontology
lists: Sample Processing and Separation Techniques Ontology
lists: Santa Barbara Coastal Observation Ontology
lists: Semantic Types Ontology
lists: Semantic Web for Earth and Environment Technology Ontology
lists: Semanticscience Integrated Ontology
lists: Single-Nucleotide Polymorphism Ontology
lists: Situation-Based Access Control Ontology
lists: Taxonomic Rank Vocabulary
lists: Taxonomy for Rehabilitation of Knee Conditions
lists: Terminological and Ontological Knowledge Resources Ontology
lists: Tick Gross Anatomy Ontology
lists: Tissue Microarray Ontology
lists: Traditional Medicine Constitution Value Set
lists: Traditional Medicine Meridian Value Sets
lists: Traditional Medicine Other Factors Value Set
lists: Traditional Medicine Signs and Symptoms Value Set
lists: Translational Medicine Ontology
lists: Tribolium Ontology
lists: Units Ontology
lists: Units of Measurement Ontology
lists: Upper-Level Cancer Ontology
lists: Vertebrate Homologous Organ Group Ontology
lists: Veterans Health Administration National Drug File
lists: Vital Sign Ontology
lists: WHO Adverse Reaction Terminology
lists: Web-Service Interaction Ontology
lists: Wheat Trait Ontology
lists: XEML Environment Ontology
lists: suicideo
lists: suicideonto
lists: Pseudogene
lists: Terminology for the Description of Dynamics
lists: Gene Regulation Ontology
lists: UBERON
lists: CHEBI
lists: Cognitive Paradigm Ontology
lists: Emotion Ontology
lists: Clinical Measurement Ontology
lists: Measurement Method Ontology
lists: NCI Thesaurus
lists: Ontology for Biomedical Investigations
lists: Biological Pathways Exchange
is listed by: Biositemaps
is listed by: FORCE11
is related to: Provisional Cell Ontology
has parent organization: National Center for Biomedical Ontology
has parent organization: Stanford University; Stanford; California
has parent organization: Stanford Center for Biomedical Informatics Research
is parent organization of: NCBO Annotator
NIGMS U24 GM143402 PMID:19483092
PMID:21672956
PMID:18999306
Free, Available for download, Freely available nif-0000-23346, r3d100012344 https://www.force11.org/node/4646
https://doi.org/10.17616/R3J362
SCR_002713 BioPortal Knowledgebase 2026-02-17 09:59:50 328
3D-Interologs
 
Resource Report
Resource Website
3D-Interologs (RRID:SCR_003101) 3D-interologs data or information resource, production service resource, analysis service resource, database, service resource, data analysis service Database of physical protein-protein interactions across multiple genomes. Based on 3D-domain interolog mapping and a scoring function, protein-protein interactions are inferred by using three-dimensional (3D) structure heterodimers to search the UniProt database. For a query protein, the database utilizes BLAST to identify homologous proteins and the interacting partners from multiple species. Based on the scoring function and structure complexes, it provides the statistic significances, the interacting models (e.g. hydrogen bonds and conserved amino acids), and functional annotations of interacting partners of a query protein. The identification of orthologous proteins of multiple species allows the study of protein-protein evolution, protein functions, and cross-referencing of proteins. interolog, protein-protein interaction, blast, homolog, protein, interaction, function is related to: IntAct
is related to: UniProt
is related to: Gene Ontology
has parent organization: National Chiao Tung University; Hsinchu; Taiwan
PMID:21143789 Resource:OMICtools, Resource:UniProt nif-0000-00554, OMICS_01896 https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-11-S3-S7 SCR_003101 2026-02-17 10:00:04 0

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