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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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University of Cincinnati Research and Training in Cardiovascular Biology Resource Report Resource Website |
University of Cincinnati Research and Training in Cardiovascular Biology (RRID:SCR_003860) | UC Research and Training in Cardiovascular Biology | medical school program resource, graduate program resource, postdoctoral program resource, organization portal, training resource, degree granting program, portal, data or information resource | Our 24 faculty members approach the Research and Training in Cardiovascular Biology program from different subspecialties that include genetics, metabolism, development, cellular biology, systems biology, structural biology, biophysics, pharmacology, molecular biology, bioinformatics and biochemistry. While these subspecialties are clearly diverse, our faculty collaboratively leverages these areas toward the common goal of understanding cardiovascular disease from the gene all the way up to integrated organism function (systems biology). This diverse array of subspecialties provides a truly unique training environment that few centers can match. Another critical aspect of our training program is our steadfast commitment to a superior and nurturing training environment for our predoctoral trainees, postdoctoral trainees and clinician-scientists. Our training faculty are uniformly committed to monitoring our personnel for success in every way possible, to not only ensure their future placement in the academic ranks but to also build a stronger cardiovascular community around the country. The current National Institutes of Health-sponsored Research and Training in Cardiovascular Biology was instituted in 1978 by Arnold Schwartz, MD, PhD. This program has trained more than 120 scientists, who have pursued independent research careers and are holding prominent scientific positions worldwide. Our trainees have been distinguished as chairs of basic science departments, directors of centers or pharmaceutical companies, clinical directors and tenured faculty members in academic research. The overall emphasis continues to focus on integrative training and well-rounded knowledge of the fundamentals in biochemical, molecular, physiological and pharmacological underpinnings of cardiovascular disease. Dr. Schwartz has been a constant guiding force since the program was established. The University of Cincinnati, with Cincinnati Children's, has also developed a reputation as a leading center for the generation and analysis of genetically modified mouse models for interrogation of gene-disease relationships in the heart. This theme has been expanded to incorporate molecular genomics, proteomics and bioinformatics, as we continue to be among the leaders in the nation in molecular pathway analysis associated with single gene manipulations in the hearts of mice. Most faculty and trainees are using these approaches, but they are also well-versed in many other aspects of cardiovascular science, including excellence in basic physiology, pharmacology, biochemistry, structural biology and molecular biology. Thus, we are a rare conglomeration of faculty in which all aspects of cardiovascular biology are practiced, starting with cutting-edge molecular and genetic approaches, spanning more traditional cellular and whole animal approaches to build an integrated network of functional and disease-relevant data and extending to translational research incorporating cell therapy. | cardiovascular disease, heart, mouse model, cardiovascular system | has parent organization: University of Cincinnati College of Medicine; Ohio; USA | NIH | nif-0000-02100 | SCR_003860 | University of Cincinnati Research Training in Cardiovascular Biology | 2026-02-16 09:46:16 | 0 | |||||||
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Accelerating Medicines Partnership - Alzheimers Resource Report Resource Website |
Accelerating Medicines Partnership - Alzheimers (RRID:SCR_003742) | AMP Alzheimer's, AMP Alzheimer's Disease | data or information resource, organization portal, consortium, portal | The Alzheimer's disease arm of the Accelerating Medicines Partnership (AMP) that will identify biomarkers that can predict clinical outcomes, conduct a large scale analysis of human AD patient brain tissue samples to validate biological targets, and to increase the understanding of molecular pathways involved in the disease to identify new potential therapeutic targets. The initiative will deposit all data in a repository that will be accessible for use by the biomedical community. The five year endeavor, beginning in 2014, will result in several sets of project outcomes. For the biomarkers project, tau imaging and EEG data will be released in year two, as baseline data becomes available. Completed data from the randomized, blinded trials will be added after the end of the five year studies. This will include both imaging data and data from blood and spinal fluid biomarker studies. For the network analysis project, each project will general several network models of late onset AD (LOAD) and identify key drivers of disease pathogensis by the end of year three. Years four and five will be dedicated to validating the novel targets and refining the network models of LOAD, including screening novel compounds or drugs already in use for other conditions that may have the ability to modulate the likely targets. | drug, drug development, biomarker, data sharing, consortium, disease target, drug design, brain tissue, brain, tissue, clinical, neuroimaging, tau, blood, cerebral spinal fluid, eeg, clinical trial, amyloid beta, neurofibrillary tangle |
is listed by: Consortia-pedia is related to: Accelerating Medicines Partnership Autoimmune Diseases of Rheumatoid Arthritis and Lupus is related to: Accelerating Medicines Partnership Type 2 Diabetes Knowledge Portal (AMP-T2D) is related to: Accelerating Medicines Partnership Type 2 Diabetes Knowledge Portal (AMP-T2D) is related to: Accelerating Medicines Partnership Autoimmune Diseases of Rheumatoid Arthritis and Lupus has parent organization: Foundation for the National Institutes of Health has parent organization: Accelerating Medicines Partnership |
NIH ; Industry partners |
nlx_157974 | SCR_003742 | Accelerating Medicines Partnership - Alzheimer's Disease, Accelerating Medicines Partnership - Alzheimer's, Accelerating Medicines Partnership Alzheimer's Disease | 2026-02-16 09:46:14 | 0 | |||||||
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elements of morphology Resource Report Resource Website 1+ mentions |
elements of morphology (RRID:SCR_003707) | international standard specification, narrative resource, data set, data or information resource, standard specification | Data set of standardized terms used to describe human morphology including definitions of terms for the craniofacies in general, the major components of the face, and the hands and feet. This provides a uniform and internationally accepted terms to describe the human phenotype. | dysmorphology, morphology, malformation, face, hand, foot, facial feature, phenotype, nose, philtrum, ear, lip, mouth, oral region, head, face, periorbital, terminology, vocabulary |
is used by: NIF Data Federation has parent organization: National Human Genome Research Institute |
NIH | PMID:19127575 PMID:19125436 PMID:19125433 PMID:19125428 PMID:19152422 PMID:19152421 |
Public domain, Acknowledgement requested | nlx_157874 | SCR_003707 | Human Malformation Terminology, Elements of Morphology: Human Malformation Terminology | 2026-02-16 09:46:14 | 4 | ||||||
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Accelerating Medicines Partnership Autoimmune Diseases of Rheumatoid Arthritis and Lupus Resource Report Resource Website |
Accelerating Medicines Partnership Autoimmune Diseases of Rheumatoid Arthritis and Lupus (RRID:SCR_003731) | AMP Autoimmune, AMP RA/SLE | data or information resource, organization portal, consortium, portal | The autoimmune disease arm of the Accelerating Medicine Partnership (AMP), which aims to identify and validate the most promising biological targets of disease for new diagnostic and drug development, that is focused on rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). They seek to identify shared common flaws in inflammation, particularly those that are shared with a larger number of autoimmune disorders which can cause severe disability, greatly affect quality of life, and are associated with an increased risk of death. This project aims to reveal biomarkers and biological targets for drug development, matching existing drugs to patients with specific molecular profiles who are most likely to benefit. The research plan proposes a 5 year process. Year one will include startup activities such as validation of tissue acquisition processes and analytic technologies, and the development of operating procedures. The second year will focus on identification of disease specific pathways by comparing data from patients and healthy individuals. Years 3-5 will expand the scale to include comparisons of different subsets of patients with RA or lupus to allow molecularly based patient stratification for precise treatment. The final 12 months (2019) will also include preliminary target validation. The data will be made publicly available through an internet-based information portal. | drug, drug development, biomarker, data sharing, consortium, gene expression, signaling, tissue, organ, synovium, kidney, skin, blood cell, inflammation |
is listed by: Consortia-pedia is related to: Accelerating Medicines Partnership - Alzheimers is related to: Accelerating Medicines Partnership - Alzheimers is related to: Accelerating Medicines Partnership Type 2 Diabetes Knowledge Portal (AMP-T2D) has parent organization: Foundation for the National Institutes of Health has parent organization: Accelerating Medicines Partnership |
NIH ; Industry partners |
nlx_157975 | SCR_003731 | Accelerating Medicines Partnership - Autoimmune, AMP Autoimmune Diseases of Rheumatoid Arthritis and Lupus, AMP RA/SLE Program, Accelerating Medicines Partnership - Autoimmune Diseases, Accelerating Medicines Partnership - Arthritis, AMP Rheumatoid arthritis and lupus, Accelerating Medicines Partnership - Autoimmune Diseases of Rheumatoid Arthritis and Lupus | 2026-02-16 09:46:11 | 0 | |||||||
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PubMed Central Resource Report Resource Website 100+ mentions |
PubMed Central (RRID:SCR_004166) | PMC | database, service resource, data or information resource, storage service resource | Collection of full text archive of biomedical and life sciences journal literature at U.S. National Institutes of Health National Library of Medicine (NIH/NLM). With PubMed Central, NCBI is taking lead in preserving and maintaining open access to electronic literature. Value of PubMed Central, in addition to its role as an archive, lies in what can be done when data from diverse sources is stored in common format in single repository. All articles in PMC are free (sometimes on a delayed basis). Some journals go beyond free, to Open Access. | literature, biomedical, life, science, journal, repository, electronic, literature, gold standard |
uses: PubReader is used by: NIH Heal Project is listed by: OMICtools is related to: PubMed is related to: JISC Open Citations is related to: Biotea is related to: NIF Registry Automated Crawl Data is related to: NIF Literature is related to: Europe PubMed Central is related to: PubReader has parent organization: NCBI |
NIH | Free, Some open access - authors retain copyright, | nlx_18862, OMICS_01193 | SCR_004166 | 2026-02-16 09:46:17 | 248 | |||||||
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NeuroWiki Resource Report Resource Website |
NeuroWiki (RRID:SCR_004066) | NeuroWiki | narrative resource, training material, software resource, source code, data or information resource, curriculum material |
Curriculum materials for an Introduction to Neurobiology course for undergraduate and graduate students. The course focuses on the analysis of neurons and neural circuits for behavior using the fundamental principles of neuroscience. From the online course syllabus, the 24 units that make up the course may be directly accessed. Each unit contains a reading, links to at least one simulation, and a problem set. A list of all available simulations can be found here: https://neurowiki.case.edu/wiki/Simulations. * 25 simulations are written in JavaScript and will run in any browser. Source code: https://github.com/CWRUChielLab/JSNeuroSim * Pre-compiled executables (Windows, Mac, Linux) are available for 1 desktop simulation, the Nernst Potential Simulator. Source code: https://github.com/CWRUChielLab/Nernst Structure of the Course * Solving problems based on simulations of neuronal components, neurons, and simple circuits to understand how they work. * For advanced students, writing a neuroscience Wikipedia article, critical review, or grant, in stages. |
simulation, neuron, neural circuit, neurobiology, neuroscience | has parent organization: Case Western Reserve University; Ohio; USA | Case Western Reserve University; Ohio; USA ; Active Learning Fellowship ; NIH ; Graduate Assistance in Areas of National Need |
Text:, Creative Commons Attribution-NonCommercial-ShareAlike License, 4.0 International, Nernst Potential Simulator:, GNU General Public License, v3, JavaScript simulations:, GNU Affero General Public License, v3 | nlx_158502 | SCR_004066 | 2026-02-16 09:46:11 | 0 | |||||||
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PharmKGB Resource Report Resource Website 100+ mentions |
PharmKGB (RRID:SCR_025580) | knowledge base, data or information resource | NIH-funded resource that provides information about how human genetic variation affects response to medications. PharmGKB collects, curates and disseminates knowledge about clinically actionable gene-drug associations and genotype-phenotype relationships. | human genetic variation affects, response to medications, clinically actionable gene-drug associations, genotype-phenotype relationships, | NIH | Free, Freely available, | SCR_025580 | Pharmacogenomics Knowledgebase | 2026-02-15 09:23:57 | 104 | |||||||||
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NIH PRECISION Human Pain Network Resource Report Resource Website 10+ mentions |
NIH PRECISION Human Pain Network (RRID:SCR_025458) | data or information resource, topical portal, disease-related portal, portal | Project titled Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins, and Nature of Human Pain (PRECISION) Network to develop meaningful resource for knowledge transfer, and to integrate and share Human Pain Associated Genes and Cell Datasets. Building knowledge platform to visualize, query, and interact with these data will support researchers and help accelerate dissemination of vital data to the larger scientific community. These goals align with NIH Helping to End Addiction Long-term (HEAL) Initiative, which seeks to accelerate the discovery and successful translation of non-addictive pain therapeutics. PRECISION Human Pain Network will leverage prior interdisciplinary collaboration to create workflows, tools, and infrastructure to define data and metadata types, to improve data management and sharing, and to integrate datasets and visualization tools. | Human pain network, human pain associated genes and cell datasets, knowledge platform, HEAL, integrated data, |
is related to: SPARC Portal is related to: Harmonized DRG and TG Reference Atlas |
NIH | Free, Freely available | SCR_025458 | PRECISION Pain Network | 2026-02-15 09:23:00 | 13 | ||||||||
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BETSY Resource Report Resource Website |
BETSY (RRID:SCR_026239) | source code, software resource | Software system for performing bioinformatics analyses. System includes knowledge base where the capabilities of bioinformatics software is explicitly and formally encoded. Backwards-chaining rule-based expert system comprised of data model that can capture richness of biological data, and inference engine that reasons on knowledge base to produce workflows. Knowledge base is populated with rules to analyze microarray and next generation sequencing data. | produce workflows, performing bioinformatics analyses, microarray data analysis, next generation sequencing data analysis, | Cancer Prevention and Research Institute of Texas ; NIH |
PMID:28052928 | Free, Available for download, Freely available, | SCR_026239 | Bioinformatics ExperT SYstem | 2026-02-15 09:23:59 | 0 | ||||||||
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Roadmap Resource Report Resource Website 10+ mentions |
Roadmap (RRID:SCR_017207) | software application, software resource | Software tool to display surface of macromolecule and its properties. Uses projections to map van der Waals or solvent accessible surface of macromolecule onto plane., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | Display, surface, macromolecule, property, projection, van der Waal | is related to: Purdue University; West Lafayette; Indiana | NSF ; NIH ; Medical Research Council |
PMID:8384042 | THIS RESOURCE IS NO LONGER IN SERVICE | SCR_017207 | 2026-02-15 09:21:59 | 14 | ||||||||
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GlimmerHMM Resource Report Resource Website 500+ mentions |
GlimmerHMM (RRID:SCR_002654) | GlimmerHMM | source code, software resource | A gene finder based on a Generalized Hidden Markov Model (GHMM). Although the gene finder conforms to the overall mathematical framework of a GHMM, additionally it incorporates splice site models adapted from the GeneSplicer program and a decision tree adapted from GlimmerM. It also utilizes Interpolated Markov Models for the coding and noncoding models . Currently, GlimmerHMM's GHMM structure includes introns of each phase, intergenic regions, and four types of exons (initial, internal, final, and single). | gene, hidden markov model |
is related to: Glimmer has parent organization: Johns Hopkins University; Maryland; USA |
NIH ; NLM R01-LM06845; NLM R01-LM007938 |
PMID:15145805 | Free, Available for download, Freely available | nlx_156092 | SCR_002654 | GlimmerHMM - Eukaryotic Gene-Finding System | 2026-02-15 09:18:22 | 576 | |||||
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neurospy Resource Report Resource Website |
neurospy (RRID:SCR_007016) | neurospy | source code, software resource | neurospy is a free software for functional imaging of fast neuronal activity. neurospy is a modular cross-platform application framework written in Java for the NetBeans Platform. At this time it runs on Windows XP-based LeCroy oscilloscopes and drives acousto-optic scanners via USB using the Analog Devices 9959 Direct Digital Synthesis chip. This combination makes one of the most powerful systems for scanning microscopy available today at any price. neurospy is very easy to port to other kinds of acquisition and scanning hardware. | imaging, neuron, microscopy, functional imaging, java, neuronal activity |
has parent organization: SourceForge has parent organization: Howard Hughes Medical Institute has parent organization: Salk Institute for Biological Studies has parent organization: University of California at San Diego; California; USA |
Howard Hughes Medical Institute ; NIH |
PMID:17684546 | Open unspecified license | nlx_149367 | SCR_007016 | 2026-02-15 09:19:25 | 0 | ||||||
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vhlab-microscopyimageanalysis-matlab Resource Report Resource Website 1+ mentions |
vhlab-microscopyimageanalysis-matlab (RRID:SCR_024450) | software application, source code, software resource | Software Matlab app for analysis of high density imaging data like that from Array Tomography. | Matlab, array tomography, super-resolution imaging, high density imaging data, high density imaging data analysis, | NIH | Free, Available for download, Freely available | SCR_024450 | 2026-02-15 09:23:32 | 1 | ||||||||||
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Bio-Synthesis Resource Report Resource Website 100+ mentions |
Bio-Synthesis (RRID:SCR_000820) | material resource, biomaterial supply resource | A commercial supplier of custom synthetic molecules. They specialize in peptides, oligonucleotides, bioconjugation, molecular biology services, proteins and specialty chemistry. | antibody, synthetic molecule, peptides, oligonucleotide, bioconjugation, protein | is listed by: ScienceExchange | NIH 263-00050713-01 | nlx_152297, SciEx_516 | SCR_000820 | Bio-Synthesis Inc. | 2026-02-15 09:17:59 | 167 | ||||||||
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Biospecimens/Biorepositories: Rare Disease-HUB (RD-HUB) Resource Report Resource Website |
Biospecimens/Biorepositories: Rare Disease-HUB (RD-HUB) (RRID:SCR_004327) | RD-HUB | material resource, biomaterial supply resource | A database of biospecimens collected, stored, and distributed by biorepositories in the United States and around the globe. Its goals are: To help and assist interested parties and investigators search, locate, and identify desired biospecimens needed for their research; to facilitate collaboration and sharing of material and data among investigators across the globe; to accelerate research to facilitate the discovery of new treatments, therapeutics and eventually cures for rare diseases as well as common diseases; to identify, locate and increase the awareness of existing biorepositories across the globe; and to link the RD-HUB with the Global Rare Diseases Patient Registry and Data Repository (GRDR). | rare disease, disease, public |
lists: NIDDK Central Repository lists: National Disease Research Interchange is listed by: NIH Data Sharing Repositories is listed by: One Mind Biospecimen Bank Listing is listed by: Accelerated Cure Project MS Repository is listed by: Cooperative Human Tissue Network Western Division at Vanderbilt University Medical Center is listed by: NIDDK Information Network (dkNET) is related to: GRDR has parent organization: Office of Rare Diseases Research |
Rare disease, Aging | NIH | PMID:20609392 | Public, The community can contribute to this resource | nlx_143682 | http://biospecimens.ordr.info.nih.gov/ | SCR_004327 | Biospecimens / Biorepositories: Rare Disease-HUB, Biospecimens/Biorepositories: Rare Disease-HUB, Rare Disease-HUB | 2026-02-15 09:18:45 | 0 | |||
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LONI MiND Resource Report Resource Website |
LONI MiND (RRID:SCR_004820) | MiND | service resource, software resource | The MiND: Metadata in NIfTI for DWI framework enables data sharing and software interoperability for diffusion-weighted MRI. This site provides specification details, tools, and examples of the MiND mechanism for representing important metadata for DWI data sets at various stages of post-processing. MiND framework provides a practical solution to the problem of interoperability between DWI analysis tools, and it effectively expands the analysis options available to end users. To assist both users and developers in working with MiND-formatted files, we provide a number of software tools for download. * MiNDHeader A utility for inspecting MiND-extended files. * I/O Libraries Programming libraries to simplify writing and parsing MiND-formatted data. * Sample Files Example files for each MiND schema. * DIRAC LONI''s Diffusion Imaging Reconstruction and Analysis Collection is a DWI processing suite which utilizes the MiND framework. | diffusion magnetic resonance imaging, metadata, dwi, dti, software interoperability, data sharing | has parent organization: David Geffen School of Medicine at UCLA; California; USA | NIH ; NCRR ; NIMH ; NCRR 1U54RR021813-01; NIGMS 5T32GM008042-25; NCRR P41 RR013642; NIMH R01 MH71940; NIBIB EB008432; NIBIB EB008281; NIBIB EB007813; NICHD HD050735 |
PMID:20206274 | nlx_143920 | http://mind.loni.ucla.edu/ | SCR_004820 | MiND: Metadata in NIfTI for DWI, Metadata in NIfTI for DWI | 2026-02-15 09:18:49 | 0 | |||||
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USIDNET DNA and Cell Repository Resource Report Resource Website |
USIDNET DNA and Cell Repository (RRID:SCR_004661) | USIDNET Repository | material resource, biomaterial supply resource | The USIDNET DNA and Cell Repository has been established as part of an NIH-funded program - the US Immunodeficiency Network - to provide a resource of DNA and functional lymphoid cells obtained from patients with various primary immunodeficiency diseases. These uncommon disorders include patients with defects in T cell, B cell and/or granulocyte function as well as patients with abnormalities in antibodies / immunoglobulins, complement and other host defense mechanisms. All samples in this Repository have been de-identified to protect the privacy of the individual donors. The USIDNET also operates a Patient Data Registry in addition to this Repository and certain clinical data relating to a specific sample may be available through the Registry for some of the patient samples in the Repository collection. Materials in the collection are being made available at modest cost to qualified investigators in academic and commercial organizations in an effort to stimulate research to increase understanding of these orphan diseases and to promote development of new treatments. Requestors are required to complete a Statement of Research Intent briefly describing their proposed use of materials obtained from the Repository and must sign an Assurance agreeing to conditions established by USIDNET for distribution of samples from its collection. Requestors wishing to obtain additional clinical data specific to individual samples in the Repository collection must make a separate application for that information to the Registry (see www.usidnet.org) Physicians or Patients wishing to submit cell samples for the Repository collection should first contact Coriell to arrange for the Repository to send them the correct sample collection tubes as well as prepaid mailers for returning the collected sample(s) to Coriell. Separate collection and shipping procedures may be involved depending on how many samples are to be shipped at one time and whether the shipment will involve freshly obtained blood or already established cell lines. | clinical data, dna, functional lymphoid cell, cell, lymphoid cell, blood, cell line, immunodeficiency disease, primary immunodeficiency disease |
is listed by: One Mind Biospecimen Bank Listing has parent organization: Coriell Cell Repositories has parent organization: USIDNET: US Immunodeficiency Network |
Immunodeficiency disease | NIH | PMID:32880085 PMID:24711005 |
Public: Materials in the collection are being made available at modest cost to qualified investigators in academic and commercial organizations in an effort to stimulate research to increase understanding of these orphan diseases and to promote development of new treatments. | nlx_143858 | SCR_004661 | US Immunodeficiency Network DNA Cell Repository, US Immunodeficiency Network DNA and Cell Repository, USIDNET DNA Cell Repository, US Immunodeficiency Network Repository | 2026-02-15 09:18:52 | 0 | ||||
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KI Biobank - TwinGene Resource Report Resource Website 10+ mentions |
KI Biobank - TwinGene (RRID:SCR_006006) | TwinGene | material resource, biomaterial supply resource | In collaboration with GenomeEUtwin, the TwinGene project investigates the importance of quantitative trait loci and environmental factors for cardiovascular disease. It is well known that genetic factors are of considerable importance for some familial lipid syndromes and that Type A Behavior pattern and increased lipid levels infer increased risk for cardiovascular disease. It is furthermore known that genetic factors are of importance levels of blood lipid biomarkers. The interplay of genetic and environmental effects for these risk factors in a normal population is less well understood and virtually unknown for the elderly. In the TwinGene project twins born before 1958 are contacted to participate. Health and medication data are collected from self-reported questionnaires, and blood sampling material is mailed to the subject who then contacts a local health care center for blood sampling and a health check-up. In the simple health check-up, height, weight, circumference of waist and hip, and blood pressure are measured. Blood is sampled for DNA extraction, serum collection and clinical chemistry tests of C-reactive protein, total cholesterol, triglycerides, HDL and LDL cholesterol, apolipo��protein A1 and B, glucose and HbA1C. The TwinGene cohort contains more than 10000 of the expected final number of 16000 individuals. Molecular genetic techniques are being used to identify Quantitative Trait Loci (QTLs) for cardiovascular disease and biomarkers in the TwinGene participants. Genome-wide linkage and association studies are ongoing. DZ twins have been genome-scanned with 1000 STS markers and a subset of 300 MZ twins have been genome-scanned with Illumina 317K SNP platform. Association of positional candidate SNPs arising from these genomscans are planned. The TwinGene project is associated with the large European collaboration denoted GenomEUtwin (www.genomeutwin.org, see below) which since 2002 has aimed at gathering genetic data on twins in Europe and setting up the infrastructure needed to enable pooling of data and joint analyses. It has been the funding source for obtaining the genome scan data. Types of samples: * EDTA whole blood * DNA * Serum Number of sample donors: 12 044 (sample collection completed) | quantitative trait loci, environmental factor, cardiovascular disease, environment, genetic, gene, lipid syndrome, lipid, health, medication, questionnaire, c-reactive protein, total cholesterol, triglyceride, hdl, ldl, cholesterol, apolipo-protein a1, apolipo-protein b, glucose, hba1c, genome-wide linkage study, genome-wide association study, genome |
is listed by: One Mind Biospecimen Bank Listing is related to: GenomEUtwin is related to: Swedish Twin Registry has parent organization: Karolisnka Biobank |
Twin | NIH ; European Union ; VR ; SSF |
nlx_151387 | http://ki.se/ki/jsp/polopoly.jsp?d=29354&a=31600&l=en | SCR_006006 | 2026-02-15 09:19:17 | 19 | ||||||
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KI Biobank - HARMONY Resource Report Resource Website 1+ mentions |
KI Biobank - HARMONY (RRID:SCR_008884) | HARMONY | material resource, biomaterial supply resource | A twin study characterizing the importance of genetic factors for dementia and using discordant twin pairs to study other putative risk factors which control for genetic propensity to develop the disease. Molecular genetic studies have identified a number of mutations and other markers associated with early age of onset Alzheimer''''s disease. However, most cases of late age of onset dementia are considered sporadic, that is, without a clear genetic basis. Twin studies provide a unique opportunity to characterize the importance of genetic factors for dementia. Discordant twin pairs additionally provide the opportunity to study other putative risk factors which controlling for genetic propensity to develop the disease. In the first wave of the Study of Dementia in Swedish Twins, all SATSA twins born before 1935 have been screened for dementia symptoms. Over 190 suspects have been identified. This pilot study has been expanded to the entire registry in the study known as HARMONY. All twins aged 65 and older were invited to participate in a computer assisted telephone screening interview. A total of 13,519 individuals completed the interview (response rate = 75.9%). Dementia screening was based on the TELE, which includes the 10-item MSQ, other cognitive items (counting backwards, recalling three words, and similarities), and questions about health and daily functioning; or on Blessed scores obtained from a proxy interview. Among those screened, 1565 were positive for suspicion of dementia and were referred for complete clinical evaluation by a physician and a nurse. Once the preliminary in-person evaluation suggested that the suspected case was demented, the twin partner was also invited for an identical clinical work-up. Response rate for clinical evaluations is 71.4%. Approximately half of those visited for evaluation have been diagnosed as demented according to DSM-IV criteria, of which two-thirds have Alzheimer''''s disease. An extensive assessment of probable risk exposure is also included. Longitudinal follow-up is yet another feature of the study. Association studies with candidate genes are also being performed. Types of samples * DNA Number of sample donors * 1154 (sample collection completed) | interview, late adult human, clinical evaluation, association study, candidate gene, gene, risk factor, twin, longitudinal |
is listed by: One Mind Biospecimen Bank Listing is related to: Swedish Twin Registry is related to: KI Biobank - SATSA has parent organization: Karolisnka Biobank |
Dementia, Alzheimer''''s disease, Discordant twin, Aging | NIH | nlx_151298 | http://ki.se/en/meb/dementia-in-swedish-twins-harmony | SCR_008884 | Dementia in Swedish Twins (HARMONY) | 2026-02-15 09:19:58 | 2 | |||||
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DrugCentral Resource Report Resource Website 100+ mentions |
DrugCentral (RRID:SCR_015663) | web application, data or information resource, database, software resource | Database of drug information created and maintained by the Division of Translational Informatics at University of New Mexico. It provides information on active ingredients chemical entities, pharmaceutical products, drug mode of action, indications, and pharmacologic action. | drug, chemical, pharmaceutical, active ingredient, translational informatics, FASEB list | has parent organization: University of New Mexico; New Mexico; USA | NIH 1U54CA189205-01 | PMID:27789690 | Freely Available, Free, Available for download | SCR_015663 | Drug Central, DrugCentral: Online Drug Compendium | 2026-02-15 09:20:56 | 116 |
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