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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_0243
Organism: Homo sapiens (Human)
Disease: Pancreatic adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Established from a xenograft produced by implantation of cells from the tumor of a patient with cancer of the pancreas in a nude mouse (CLS=300162)., Population: Caucasian., Part of: NCI RAS program mutant KRAS cell line panel., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0243 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0008
Organism: Homo sapiens (Human)
Disease: EBV-related Burkitt lymphoma
Category: Cancer cell line
Comments: Caution: TP53 mutation indicated incorrectly as being at c.637C>T in PubMed=2052620., Population: African; Kenyan., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: Human variation panel., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Proper citation: RRID:CVCL_0008 Copy
https://web.expasy.org/cellosaurus/CVCL_1167
Organism: Homo sapiens (Human)
Disease: Medulloblastoma, SHH-activated, TP53-mutant
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1167 Copy
https://web.expasy.org/cellosaurus/CVCL_1196
Organism: Homo sapiens (Human)
Disease: Childhood chronic myelogenous leukemia, BCR-ABL1 positive
Category: Cancer cell line
Comments: Population: Caucasian., Part of: LL-100 blood cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1196 Copy
https://web.expasy.org/cellosaurus/CVCL_2034
Organism: Homo sapiens (Human)
Disease: Endometrial carcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2034 Copy
https://web.expasy.org/cellosaurus/CVCL_1205
Organism: Homo sapiens (Human)
Disease: Endometrioid stromal sarcoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1205 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_1171
Organism: Homo sapiens (Human)
Disease: Pharyngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: OPC-22 oral and pharyngeal cancer cell line panel., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: KuDOS 95 cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1171 Copy
https://web.expasy.org/cellosaurus/CVCL_1170
Organism: Homo sapiens (Human)
Disease: Anaplastic large cell lymphoma, ALK-positive
Category: Cancer cell line
Comments: Virology: Contains 4 copies of an integrated murine leukemia virus closely related to that found in EKVX. Three of the integration sites are within the introns of genes OPA1, TNFRSF6B and ZNF767 (PubMed=25355872; PubMed=30629668)., Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1170 Copy
https://web.expasy.org/cellosaurus/CVCL_0244
Organism: Homo sapiens (Human)
Disease: Burkitt lymphoma
Category: Cancer cell line
Comments: Virology: Infected by DG-75 retrovirus, a replication-competent, murine leukemia-related retrovirus. Constitutively produces the virus., Virology: EBV-negative., Population: Jewish; Ashkenazi., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0244 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_A762
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Part of: MD Anderson Cell Lines Project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_A762 Copy
https://web.expasy.org/cellosaurus/CVCL_1173
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1173 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0248
Organism: Homo sapiens (Human)
Disease: Colon adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Part of: AstraZeneca Colorectal cell line (AZCL) panel.
Proper citation: RRID:CVCL_0248 Copy
https://web.expasy.org/cellosaurus/CVCL_2019
Organism: Homo sapiens (Human)
Disease: Pleural sarcomatoid mesothelioma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: May be misclassified. While still annotated as a pleural sarcomatoid mesothelioma cell line, a variety of omics methods are classifying this cell line as a fibroblast (DOI=10.1101/166199; DepMap=ACH-000742)..
Proper citation: RRID:CVCL_2019 Copy
https://web.expasy.org/cellosaurus/CVCL_1179
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma germinal center B-cell type
Category: Cancer cell line
Comments: Caution: A TP53 mutation is indicated as being at p.Ala138Pro (c.412G>C) in PubMed=17363600 but has not been confirmed by CCLE and Cosmic-CLP., Miscellaneous: Originally assigned to be from a B-cell non-Hodgkin lymphoma, immunoblastic-type., Population: Caucasian., Part of: TCGA-110-CL cell line panel., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: ICLC Cat# HTL99022, RRID:CVCL_1179 Copy
https://web.expasy.org/cellosaurus/CVCL_2438
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2438 Copy
https://web.expasy.org/cellosaurus/CVCL_1179
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma germinal center B-cell type
Category: Cancer cell line
Comments: Caution: A TP53 mutation is indicated as being at p.Ala138Pro (c.412G>C) in PubMed=17363600 but has not been confirmed by CCLE and Cosmic-CLP., Miscellaneous: Originally assigned to be from a B-cell non-Hodgkin lymphoma, immunoblastic-type., Population: Caucasian., Part of: TCGA-110-CL cell line panel., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-47, RRID:CVCL_1179 Copy
https://web.expasy.org/cellosaurus/CVCL_1179
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma germinal center B-cell type
Category: Cancer cell line
Comments: Caution: A TP53 mutation is indicated as being at p.Ala138Pro (c.412G>C) in PubMed=17363600 but has not been confirmed by CCLE and Cosmic-CLP., Miscellaneous: Originally assigned to be from a B-cell non-Hodgkin lymphoma, immunoblastic-type., Population: Caucasian., Part of: TCGA-110-CL cell line panel., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: IZSLER Cat# BS TCL 228, RRID:CVCL_1179 Copy
https://web.expasy.org/cellosaurus/CVCL_1174
Organism: Homo sapiens (Human)
Disease: Thoracic SMARCA4-deficient undifferentiated tumor
Category: Cancer cell line
Comments: Caution: Originally classified as originating from a lung small cell carcinoma, but is reclassified as a thoracic SMARCA4-deficient undifferentiated tumor based on a number of criteria (PubMed=38180245)., Population: Caucasian., Part of: KuDOS 95 cell line panel., Part of: JFCR39 cancer cell line panel., Part of: FGFR genetic alteration cell panel (ATCC TCP-1034)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1174 Copy
https://web.expasy.org/cellosaurus/CVCL_1239
Organism: Homo sapiens (Human)
Disease: Astrocytoma
Category: Cancer cell line
Comments: Miscellaneous: Originally classified as originating from a neuroglioma, an obsolete classification. This cell line has been reclassified as an astrocytoma., Population: Caucasian., Part of: TCGA-110-CL cell line panel., Part of: PTEN genetic alteration cell panel (ATCC TCP-1030)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1239 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: IZSLER Cat# BS TCL 20, RRID:CVCL_0030 Copy
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