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Icahn School of Medicine at Mount Sinai Transgenic and Genome Editing Core Facility (RRID:SCR_027505)Copy Citation Copied
URL: https://icahn.mssm.edu/research/resources/deans-cores/transgenic-genome-editing
Proper Citation: Icahn School of Medicine at Mount Sinai Transgenic and Genome Editing Core Facility (RRID:SCR_027505)
Description: Core offers services from consultation until delivery of germline-confirmed genetically engineered mouse models (GEMMs). Uses genome editing tools such as CRISPR/Cas9 to rapidly generate GEMMs with diverse genome modifications such as humanization, large insertion, conditional knockout, base substitution and deletion. Animals produced in the CoRE are thoroughly genotyped by our comprehensive genotyping services. Supports model creation via the traditional transgenesis and the gene targeting in the embryonic stem cells. Other services provided by the CoRE include sperm cryopreservation, in vitro fertilization, rederivation and custom embryology supports.
Synonyms: Icahn School of Medicine at Mount Sinai MSSM-Transgenic and Genome Editing CoRE, MSSM-Transgenic and Genome Editing CoRE
Resource Type: service resource, access service resource, core facility
Keywords: ABRF, germline-confirmed genetically engineered mouse models, genome editing tools, CRISPR/Cas9,
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