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URL: http://www.bioconductor.org/packages/release/bioc/html/COMPASS.html
Proper Citation: COMPASS (RRID:SCR_001801)
Description: Software for combinatorial polyfunctionality analysis of single cells. It is a statistical framework that enables unbiased analysis of antigen-specific T-cell subsets. It uses a Bayesian hierarchical framework to model all observed cell-subsets and select the most likely to be antigen-specific while regularizing the small cell counts that often arise in multi-parameter space. The model provides a posterior probability of specificity for each cell subset and each sample, which can be used to profile a subject's immune response to external stimuli such as infection or vaccination.
Synonyms: Combinatorial Polyfunctionality Analysis of Single Cells, COMPASS - Combinatorial Polyfunctionality Analysis of Single Cells, COMPASS: Combinatorial Polyfunctionality Analysis of Single Cells
Resource Type: software resource
Defining Citation: PMID:26006008
Keywords: software package, mac os x, unix/linux, windows, r, flow cytometry
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