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URL: http://www.lasige.di.fc.ul.pt/webtools/proteinon/
Proper Citation: ProteInOn (RRID:SCR_005740)
Description: ProteInOn calculates semantic similarity between GO terms or proteins annotated with GO terms. It also calculates term enrichment of protein sets, by applying a term representativity score, and gives additional information on protein interactions. The query compute protein semantic similarity returns the semantic similarity scores between all proteins entered, in matrix format. The option Measure allows users to choose one of several semantic similarity measures: Resnik, Lin, or Jiang & Conrath's measures with or without the DCA approach, plus the graph-based simUI and simGIC measures. These measures are listed by order of performance as evaluated with protein sequence similarity. The option GO type allows users to choose one of the aspects of GO: molecular function, biological process and cellular component. The option Ignore IEA limits the query to non-electronic annotations, excluding evidence types: IEA, NAS, ND, NR.
Synonyms: Protein Interactions Ontology, ProteInOn - Protein Interactions and Ontology, Protein Interactions and Ontology
Resource Type: service resource, analysis service resource, production service resource, data analysis service
Keywords: protein, ontology, gene ontology, annotation, statistical analysis, term enrichment, protein interaction, semantic similarity, other analysis
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FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products |
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