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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=153323320
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Live Animals; Cryopreserved Embryo; Cryorecovery (as of 2023-10-25)
References:
Synonyms:
Notes: Origin: as for MNR except selection was for high defecation response in the open field. To Harrington in 1965 at F25 and to NIH in 1964 at F18+ (Hansen et al 1982). Now is available at Rat Resource & Research Center Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: 0000173 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=70509
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm
References:
Synonyms:
Notes: Curtiss and Dunning 1920 at Columbia University Institute for Cancer Research,To Heston 1949 (Billingham and Silvers 1959). To National Institutes of Health in 1951 (Hansen et al 1982). Subsequent sublines from Dunning or NIH. NIH Autoimmune Rat Model Repository and Development Center, Rat Resource and Research Center
Proper citation: RRID:RRRC_00158 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10040
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Originated from a Sprague-Dawley outbred colony developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for resistance to salt-induced hypertension (Dahl et al 1962a,b). Rat Resource and Research Center
Proper citation: RRID:RRRC_00056 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695055
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Inbred hypertension model linked to a mutation in Add1 gene that has been validated as one of the genes linked to hypertension in numerous human genetic studies. Inbred strain originally developed by Dr. Bianchi in Milan in 1979. Rat Resource and Research Center
Proper citation: RRID:RRRC_00794 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9999145
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: The F344/NCr rat strain was received into the NIH Genetic Resources program in 1987, now maintained at NCI Animal production program Rat Resource and Research Center
Proper citation: RRID:RRRC_00734 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245556
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: WKHT rats are derived from a cross between SHR and WKY. Brother/sister inbreeding of the hybrids and successive generations was performed, selecting for the hypertension, but not the behavioral hyperactivity, of the SHR. Rat Resource and Research Center
Proper citation: RRID:RRRC_00664 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10000
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery
References:
Synonyms:
Notes: Curtiss and Dunning 1926 at the Columbia University Institute for Cancer Research. To Heston 1945 at F30, to National Institutes of Health 1950 at F41. Subsequent sublines from Dunning or NIH. Donated to RRRC from NIH Animal Genetic Resource Bank (NIHAGR) Rat Resource and Research Center
Proper citation: RRID:RRRC_00142 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=629509
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Live Animals; Cryorecovery
References:
Synonyms:
Notes: An outbred stock of fawn hooded rats introduced into Europe by Tschopp in the early 1970s. Maintained as an outbred stock until the mid-1980s, then brother x sister mating initiated by A.P. Provoost to produce two strains designated FHH (also known as FHR) and FHL, which differ in hypertension and proteinuria. The colony was transferred to Erasmus University. Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: RRID:RRRC_00293 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2307319
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo
References:
Synonyms:
Notes: Wistar rats with brother x sister mating and selection for low systolic blood pressure as a normotensive control for MHS. Rat Resource and Research Center
Proper citation: RRID:RRRC_00171 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482676
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: The Occidental LoS (low-saccharin-consuming) rat strain was developed from a male Holtzman Sprague-Dawley rat that did not voluntarily consume saccharin. This male was mated to several Holtzman Sprague-Dawley females and offspring displaying low saccharin consumption were selected. Selective breeding was continued in which offspring with low saccharin consumption (see phenotyping protocol) were bred. To maintain the outbred status of this colony the donor backcrosses to Hsd:SD every 4-6 generations. Rat Resource and Research Center
Proper citation: RRID:RRRC_00440 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578695
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selective breeding of Long-Evans in active two-way shuttle box for high avoidance resulted in these SHA rats. Rat Resource and Research Center
Proper citation: RRID:RRRC_00068 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6480863
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: BBDR/Rhw from R. H. William Laboratory, University of Washington, Seattle, Washington to Rat Resource & Research Center Rat Resource & Research Center
Proper citation: RRID:RRRC_00463 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482674
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: The Occidental HiS (high-saccharin-consuming) rat strain was developed from a male Holtzman Sprague-Dawley rat that voluntarily consumed high levels of saccharin.This male was mated to several Holtzman Sprague-Dawley females and offspring displaying high saccharin consumption were selected. Selective breeding was continued in which offspring with high saccharin consumption were bred. To maintain the outbred status of this colony the donor backcrosses to Hsd:SD every 4-6 generations. Rat Resource and Research Center
Proper citation: RRID:RRRC_00366 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578698
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selectively bred for 24 generations for low hypnotic response to high dose ethanol, then inbred Rat Resource and Research Center
Proper citation: RRID:RRRC_00081 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578696
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selectively bred for 24 generations for low sensitivity to ethanol then inbred. Rat Resource and Research Center
Proper citation: RRID:RRRC_00080 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578701
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selectively bred for high ethanol sensitivity for 24 generations, then inbred. Rat Resource and Research Center
Proper citation: RRID:RRRC_00079 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578700
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selectively bred for high sensitivity for ethanol hypnosis for 24 generations then inbred Rat Resource and Research Center
Proper citation: RRID:RRRC_00077 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13450922
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Genetically Epilepsy-Prone Rats (GEPR-3) have moderate levels of seizure predisposition. This colony,initially referred to as an AGS (audiogenic response score) colony, was bred to exhibit clonic convulsions (moderate seizures with an ARS of 3) following a single wild running phase in response to sound. Siezures model human generalized tonic/clonic seizures. Rat Resource and Research Center
Proper citation: RRID:RRRC_00798 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245527
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: derived from a cross between SHR/N and WKY/N starting in 1980; followed by selected brother/sister inbreedings from F2 generation forward, selecting WKHA for highest activity and lowest blood pressure Rat Resource and Research Center
Proper citation: RRID:RRRC_00663 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695083
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Wistar rats maintained at the animal facility of the Ribeirao Preto School of Medicine at the University of Sao Paulo, Brazil, were tested for audiogenic seizures, using as criteria an SI and the L1 (ref. RGD:14695082). The WAR colony foundation stock was produced by mating animals displaying at least procursive behaviors in three consecutive tests, one every 4 days (two males and four females). Each couple produced two or three lit-ters, from which selected individuals displaying the highest SI and shortest L1 were mated, at adult age,with their fathers and mothers. From the second generation on, brother and sister matings were done, in a ratio of one male to two females, selected accordingto the criteria above. Rat Resource and Research Center
Proper citation: RRID:RRRC_00697 Copy
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