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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
WKY-Tnfrsf14em1Tja/Rrrc Resource Report Resource Website |
RRID:RRRC_00796 | Rattus norvegicus | This strain was produced by injecting ZFNs targeted sequence into WKY/Cruk rat embryos. The resulting mutation 77 has a stop codon, 15 amino acids from the ZFN-binding site, that resulted in a 490 amino acids (54 kDa) truncated protein, 198 amino acids smaller than the WT protein. Rat Resource and Research Center | 00796 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm; Cryorecovery (as of 2021-11-11) | RGD_150521604, 150521604, RRRC_796, RRRC_0796, RRRC_00796 | 2026-02-07 05:09:11 | 0 | |||||
|
ACI.F344-ApcPircUwm Resource Report Resource Website |
RRID:RRRC_00718 | Rattus norvegicus | This strain develops twice the number of colonic tumors as the F344-ApcPircUwm rats (RGD:1641862). Stop codon mutation at amino acid 1137 of the Apc gene. Nucleotide chr18:26,785,272 (Baylor 3.4/rn4) A to T transversion. Rat Resource and Research Center | 00718 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm (as of 2017-02-06) | RGD_12738452, 12738452, RRRC_718, RRRC_0718, RRRC_00718 | 2026-02-07 05:09:10 | 0 | |||||
|
SD-Esr2em2Soar Resource Report Resource Website |
RRID:RRRC_00719 | Rattus norvegicus | Zinc finger nuclease targeting of exon 3 of the rat estrogen receptor-2 gene resulting in the deletion of exon 3. Rat Resource and Research Center | 00719 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm (as of 2017-01-26) | RGD_11667077, 11667077, RRRC_719, RRRC_0719, RRRC_00719 | 2026-02-07 05:09:10 | 0 | |||||
|
SD-Pgrem2Soar Resource Report Resource Website |
RRID:RRRC_00720 | Rattus norvegicus | zinc finger nucleases were used to generate a 136 bp deletion within the first exon of the progesterone receptor, resulting in a frameshift, premature stop codon, and a null. Rat Resource and Research Center | 00720 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm (as of 2017-01-26) | RGD_11667079, 11667079, RRRC_720, RRRC_0720, RRRC_00720 | 2026-02-07 05:09:10 | 0 | |||||
|
WIST-Tulane Tulane rat Resource Report Resource Website |
RRID:RRRC_00721 | Rattus norvegicus | Male Wistar rats with inbred congenital unilateral right hydronephrosis were bred from the colony described in 1979 by Friedman et al. Rat Resource and Research Center | 00721 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-01-26) | RGD_11667096, 11667096, RRRC_721, RRRC_0721, RRRC_00721 | 2026-02-07 05:09:10 | 0 | |||||
|
ACI.SD-Esr1em1Soar Resource Report Resource Website |
RRID:RRRC_00849 | Rattus norvegicus | This strain was produced by backcrossing the ZFN induced 482 deletion allele (Esr1em1Soar) in HsdHot:SD to the ACI/SegHsd background for 12 generations. ACI strain is particularly sensitive to Estrogen-induced tumorigenesis. Rat Resource and Research Center | 00849 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown (as of 2019-02-28) | RGD_14392784, 14392784, RRRC_849, RRRC_0849, RRRC_00849 | 2026-02-07 05:09:11 | 0 | |||||
|
SD-Gfapem2Mes /Rrrc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00931 | Rattus norvegicus | CRISPR/Cas9 mediated single nucleotide deletion resulting in a frameshift that creates a premature stop and generates a null allele. This strain serves as a model for Alexander disease - nulls are of interest for traumatic brain injury and many other studies of CNS disease and astrocyte response. Rat Resource and Research Center | 00931 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150519896, 150519896, RRRC_931, RRRC_0931, RRRC_00931 | 2026-02-07 05:09:11 | 1 | |||||
|
SD-Esr1em1Soar Resource Report Resource Website 1+ mentions |
RRID:RRRC_00701 | Rattus norvegicus | zinc finger nucleases were used to generate a 482 bp deletion in Esr1 gene, resulting in a knock out. Rat Resource and Research Center | 00701 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm (as of 2017-01-26) | RGD_11667088, 11667088, RRRC_701, RRRC_0701, RRRC_00701 | 2026-02-07 05:09:11 | 1 | |||||
|
BN-Spib spitzenborduere (spib) Resource Report Resource Website |
RRID:RRRC_00703 | Rattus norvegicus | Retinae display marked rosett formation in the outer nuclear layer; in the funduscopy irregular, dark pigment flecks are observed, which cannot be identified in the histology. Linkage analysis indicating at least two genes interacting. Rat Resource and Research Center | 00703 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm (as of 2017-02-10) | RGD_12743630, 12743630, RRRC_703, RRRC_0703, RRRC_00703 | 2026-02-07 05:09:11 | 0 | |||||
|
LE-Drd1em1(iCre)Berke Resource Report Resource Website 1+ mentions |
RRID:RRRC_00856 | Rattus norvegicus | The CRISPR system was used to created target insertion of iCre recombinase to the Drd1 (Drd1a) locus of the embryos of BluHsd:LE. Rat Resource and Research Center | 00856 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Live Animals (as of 2021-02-12) | RGD_14398499, 14398499, RRRC_856, RRRC_0856, RRRC_00856 | 2026-02-07 05:09:11 | 7 | |||||
|
LE-Adora2aem1(iCre)Berke Resource Report Resource Website 1+ mentions |
RRID:RRRC_00857 | Rattus norvegicus | The CRISPR system was used to created target insertion of iCre recombinase immediately after Adora2a gene, with P2A linker, of the embryos of BluHsd:LE. Rat Resource and Research Center | 00857 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Live Animals (as of 2021-02-12) | RGD_14398734, 14398734, RRRC_857, RRRC_0857, RRRC_00857 | 2026-02-07 05:09:12 | 4 | |||||
|
F344tl toothless (tl) Resource Report Resource Website |
RRID:RRRC_00749 | Rattus norvegicus | A spontaneous tooth less mutation was maintained in inbred Fisher colony maintained at the University of Massachusetts Medical School. The homozygous mutant is a 10-bp insertion near the beginning of the open reading of the Csf1 gene that yields a truncated, nonfunctional protein and an early stop codon. Rat Resource and Research Center | 00749 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11081177, 11081177, RRRC_749, RRRC_0749, RRRC_00749 | 2026-02-07 05:09:10 | 0 | |||||
|
LEW-RT1.Bm1Trg/Rrrc RT1.B Resource Report Resource Website |
RRID:RRRC_00392 | Rattus norvegicus | ENU induced mutation in a Sprague Dawley rat resulting in a phenotypic change at the RT1.B MHC locus such that antibody binding to the RT1.B locus is no longer present. Animals carrying this mutation fail to have OX-6 antibody binding to the RT1.B locus. The exact nature of the mutation has not been genetically characterized. Mutation was backcrossed onto the Lewis strain. Rat Resource and Research Center | 00392 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo; Cryopreserved Sperm | RGD_2314478, 2314478, RRRC_392, RRRC_0392, RRRC_00392 | 2026-02-07 05:09:12 | 0 | |||||
|
SD-Prl7b1tm1(cre)Soar Resource Report Resource Website |
RRID:RRRC_01013 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce Cre recombinase downstream of the Prl7b1 start site. Rat Resource and Research Center | 01013 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo; Cryopreserved Sperm (as of 2023-11-21) | RGD_401900746, 401900746, RRRC_1013, RRRC_01013 | 2026-02-07 05:09:13 | 0 | |||||
|
SD-Prl7b1em1Soar Resource Report Resource Website |
RRID:RRRC_01014 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 272 bp deletion at the Prl7b1 locus Rat Resource and Research Center | 01014 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo (as of 2023-11-21) | RGD_401900749, 401900749, RRRC_1014, RRRC_01014 | 2026-02-07 05:09:12 | 0 | |||||
|
LEW-Erap1em1Reh2786/Rrrc Resource Report Resource Website |
RRID:RRRC_00918 | Rattus norvegicus | The ZFN mRNA targeting exon 2 of Erap1 was microinjected into both the pronuclei and the cytoplasm of fertilized LEW eggs. This strain was heterozygous for a 2-bp deletion within the targeted AGGAGA sequence of Erap1. Rat Resource and Research Center | 00918 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2021-11-19) | RGD_150523780, 150523780, RRRC_918, RRRC_0918, RRRC_00918 | 2026-02-07 05:09:11 | 0 | |||||
|
F344-BE329202Tn(sb-T2/Bart3)2.198Mcwi Resource Report Resource Website |
RRID:RRRC_00345 | Rattus norvegicus | this Sleeping Beauty mutants were derived by crossing F344-Tg(T2/Bart3)2Ceb and F344-Tg(PGK2-SB11)Ceb Rat Resource & Research Center | 00345 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm | RGD_2292453, 2292453, RRRC_345, RRRC_0345, RRRC_00345 | 2026-02-07 05:09:12 | 0 | |||||
|
SD-ROSA26em1(LTR-nLuc)Ottc/Rrrc Resource Report Resource Website |
RRID:RRRC_00925 | Rattus norvegicus | The CRISPR/Case9 knock-in rats have cre recombinase-dependent expression of nanoluciferase under the control of HIV LTR promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center | 00925 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_155641248, 155641248, RRRC_925, RRRC_0925, RRRC_00925 | 2026-02-07 05:09:12 | 0 | |||||
|
F344.LE-ROSA26 em1(LTR-nLuc)Ottc/Rrrc Resource Report Resource Website |
RRID:RRRC_00926 | Rattus norvegicus | The mutated ROSA26 locus of LE-(ROSA)26 em1(LTR-nLuc)Ottc (RGD:13208223) was crossed onto Fischer344 background by backcrossing the hybrid to Fischer344 and select for the presence of mutated locus. The LE donor is CRISPR/Case9 knock-in strain that has cre recombinase-dependent expression of nanoluciferase under the control of HIV LTR promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. now deposited at Rat Resource and Research Center | 00926 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_155641247, 155641247, RRRC_926, RRRC_0926, RRRC_00926 | 2026-02-07 05:09:11 | 0 | |||||
|
F344-BI284934Tn(sb-T2/Bart3)2.185Mcwi Resource Report Resource Website |
RRID:RRRC_00367 | Rattus norvegicus | this Sleeping Beauty mutants were derived by crossing F344-Tg(T2/Bart3)2Ceb and F344-Tg(PGK2-SB11)Ceb Rat Resource & Research Center | 00367 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm | RGD_2290081, 2290081, RRRC_367, RRRC_0367, RRRC_00367 | 2026-02-07 05:09:12 | 0 |
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