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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00047267
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: egxSi145 II; unc-119(ed3) III.
Notes: egxSi145 [mex-5p::hsp-3(aa1-19)::halotag::HDEL::pie-1 3UTR + unc-119(+)] II. Superficially wild-type. Stable expression of Halotag in the ER lumen in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Xintao Fan"
Proper citation: RRID:WB-STRAIN:WBStrain00047267 Copy
http://www.wormbase.org/db/get?name=WBStrain00047268
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)|WBGene00012354(cox-4)
Genomic Alteration: WBGene00006843(unc-119), WBGene00012354(cox-4)
Availability: unknown
References:
Synonyms: cox-4(zu476[cox-4::eGFP::3XFLAG]) I; egxSi136 II; unc-119(ed3) III.
Notes: egxSi136 [mex-5p::tomm-20::halotag::pie-1 3UTR + unc-119(+)] II. GFP and 3xFLAG tags inserted into endogenous cox-4 locus to create a C-terminal translational GFP fusion. Outer membranes are stably labeled with the TOMM-20::Halotag transgene, and the mitochondria matrix are labeled with COX-4::GFP. Reference: Fan X, et al. G3 (accepted).|"Made_by: Stephanie Miller"
Proper citation: RRID:WB-STRAIN:WBStrain00047268 Copy
http://www.wormbase.org/db/get?name=WBStrain00047269
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: egxSi152 II; unc-119(ed3) III.
Notes: egxSi152 [mex-5p: tomm-20::gfp::pie-1 3UTR + unc-119(+)] II. Superficially wild-type. Stable expression of TOMM-20 tagged with GFP on the outer membranes of mitochondria in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Xintao Fan"|"Supplementary_genotype egxSi152[mex-5p: tomm-20::gfp::pie-1 3UTR + unc-119(+)] II; unc-119(ed3) III"
Proper citation: RRID:WB-STRAIN:WBStrain00047269 Copy
http://www.wormbase.org/db/get?name=WBStrain00047264
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: egxSi126 I; unc-119(ed3) III
Notes: egxSi126 [mex-5p::hsp-3(aa1-19)::halotag::HDEL::pie-1 3UTR + unc-119(+)] I. Superficially wild-type. Stable expression of Halotag in the ER lumen in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Xintao Fan"
Proper citation: RRID:WB-STRAIN:WBStrain00047264 Copy
http://www.wormbase.org/db/get?name=WBStrain00047326
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: qSi369 II; unc-119(ed3) III; qSi370 V.
Notes: qSi369 [sygl-1p::24xMS2 loops::3xflag::sygl-1::sygl1 3'UTR]. qSi370 [mex-5p:: MS2 Coat Protein::linker::sfGFP::tbb-2 3' UTR::gpd-2 intergenic sequence::H2B::mCherry::unc-54 3' UTR]. Superficially wild-type with expression of sfGFP and nuclear mCherry in germline. qSi369 and qSi370 constitute an MS2 system which allows live visualization of sygl-1 nascent transcripts in the C. elegans germline in a glp-1 mutant background. qSi370 can be prone to silencing, especially after severe starvation; silencing of GFP or mCherry expression can occur independently of one another. Maintain by picking animals with bright GFP and mCherry expression. Reference: Lee C, et al. Dev Cell. 2019 Aug 19;50(4):426-435.e4.
Proper citation: RRID:WB-STRAIN:WBStrain00047326 Copy
http://www.wormbase.org/db/get?name=WBStrain00047420
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119 (tm4063) III; wgIs797.
Notes: Made_by: DKV/MC|"Mutagen:Particle Bombardment"|"wgIs797 [flt-1::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44."
Proper citation: RRID:WB-STRAIN:WBStrain00047420 Copy
http://www.wormbase.org/db/get?name=WBStrain00047422
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119 (tm4063) III; wgIs809.
Notes: Made_by: DKV/MC|"Mutagen:Particle Bombardment"|"wgIs809 [ets-5::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44."
Proper citation: RRID:WB-STRAIN:WBStrain00047422 Copy
http://www.wormbase.org/db/get?name=WBStrain00047423
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119 (tm4063) III; wgIs810.
Notes: Made_by: DKV/MC|"Mutagen:Particle Bombardment"|"wgIs810 [C06A6.2::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44."
Proper citation: RRID:WB-STRAIN:WBStrain00047423 Copy
http://www.wormbase.org/db/get?name=WBStrain00047435
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119(ed4) III; syEx1539.
Notes: syEx1539 [nhr-246p::GFP + unc-119(+)]. Pick non-Unc to maintain. Dauer decision marker that indicates commitment to dauer formation in intestine and hypodermis. Reference: Shih, PY, et al., Dev Biol. 2019 Jun 23. pii: S0012-1606(18)30788-7.
Proper citation: RRID:WB-STRAIN:WBStrain00047435 Copy
http://www.wormbase.org/db/get?name=WBStrain00047384
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119(ed3) III; qyIs46.
Notes: qyIs46 [emb-9p::emb-9::mCherry + unc-119(+)] X. Superficially wild-type with very low penetrance (~5%) rupture. Integrated collagen::mCherry reporter. Reference: Ihara S, et al. Nat Cell Biol. 2011 Jun;13(6):641-51.|"Supplementary_genotype [emb-9p::emb-9::mCherry + unc-119(+)] X"
Proper citation: RRID:WB-STRAIN:WBStrain00047384 Copy
http://www.wormbase.org/db/get?name=WBStrain00047419
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119 (tm4063) III; wgIs782.
Notes: Made_by: DKV/MC|"Mutagen:Particle Bombardment"|"wgIs782 [ztf-14::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44."
Proper citation: RRID:WB-STRAIN:WBStrain00047419 Copy
http://www.wormbase.org/db/get?name=WBStrain00047346
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: rcSi1 II; unc-119(ed3) III.
Notes: rcSi1 [mex-5p::rpt-1::mCherry + unc-119(+)] II. RPT-1::mCherry allows visualization of the proteasome in the germline. Reference: Sampuda KL, et al. BMC Cell Biol. 2017 Apr 19;18(1):18.
Proper citation: RRID:WB-STRAIN:WBStrain00047346 Copy
http://www.wormbase.org/db/get?name=WBStrain00047721
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119(ed3) III; czIs110.
Notes: czIs110 [mex-5p::GFP::KDEL::pie-1 3UTR + unc-119(+)]. GFP::KDEL is a marker of the luminal ER in the embryo. Reference: Lee et al., J Cell Biol. 2016 Sep 12;214(6):665-76.
Proper citation: RRID:WB-STRAIN:WBStrain00047721 Copy
http://www.wormbase.org/db/get?name=WBStrain00047890
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed4) III; syIs360.
Notes: Batch Strain object requested via get_NS_ids.pl|"Generated from papers flagged positive during the last month for data type afp_strain/other_strain."|"syIs360 [ets-10p::GFP + unc-119(+)]. Dauer decision marker that indicates commitment to dauer formation in neurons and intestine. Reference: Shih, PY, et al., Dev Biol. 2019 Jun 23. pii: S0012-1606(18)30788-7."
Proper citation: RRID:WB-STRAIN:WBStrain00047890 Copy
http://www.wormbase.org/db/get?name=WBStrain00048145
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119(ed3) III.
Notes: [2021-02-02T17:27:14.041Z WBPerson1983] New Strain: Genotype: unc-119(ed3) III Reference: WBPaper00059962
Proper citation: RRID:WB-STRAIN:WBStrain00048145 Copy
http://www.wormbase.org/db/get?name=WBStrain00029956
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; wgIs18.
Notes: Generated from Paper data WBPaper00060123|"Made_by: modEncode"|"Modern strain"|"wgIs18 [lin-39::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of lin-39 coding sequence of fosmid ID#WRM0616aE11 by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029956 Copy
http://www.wormbase.org/db/get?name=WBStrain00029958
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; wgIs27.
Notes: Generated from Paper data WBPaper00060123|"Made_by: modEncode"|"Modern strain"|"wgIs27 [mab-5::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of mab-5 coding sequence of fosmid ID#WRM0640bH09 by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029958 Copy
http://www.wormbase.org/db/get?name=WBStrain00029979
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; wgIs62.
Notes: Made_by: modEncode|"Modern strain"|"wgIs62 [lin-11::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029979 Copy
http://www.wormbase.org/db/get?name=WBStrain00029976
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; gaEx290.
Notes: gaEx290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. Pick non-Unc to maintain. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)|"gaEx290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"|"gaIs290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"|"Made_by: modENCODE"|"Modern strain"|"WBStrain mapped, WBPaper00059970 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00029976 Copy
http://www.wormbase.org/db/get?name=WBStrain00029968
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; wgIs43.
Notes: Made_by: modEncode|"Modern strain"|"Supplementary_genotype unc-119(ed3) III; wgIs43[nhr-23::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]"|"wgIs43 [nhr-23::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Gerstein MB, et al. Science. 2010 Dec 24;330(6012):1775-87. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029968 Copy
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