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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=728194
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: To N 1966 at F13 from Okamoto. Okamoto, Kyoto School of Medicine, 1963, from outbred Wistar Kyoto male with marked elevation of blood pressure mated to female with slightly elevated blood pressure; brother-sister mating with contin- ued selection for spontaneous hypertension.
Proper citation: RRID:RGD_728194 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=728198
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: To N in 1979 from Flow Laboratories. Closed colony since then. BHE was started in 1942 by the Agricultural Research Service. USDA from a cross between a black and white hooded strain from Pennsylvania State College and an albino Os- borne-Mendel (also called the Yale strain) strain from Columbia University.
Proper citation: RRID:RGD_728198 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=728187
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: Strain originated from Curtiss and Dunning 1926 at the Columbia University Institute for Cancer Research. To Heston 1945 at F30, to National Institutes of Health 1950 at F41. Subsequent sublines from Dunning or NIH.
Proper citation: RRID:RGD_728187 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=631282
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: This speed congenic strain contains an F344 chromsome 10 segment transferred to a DA background.
Proper citation: RRID:RGD_631282 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1566445
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: This congenic strain contains a region of BN/SsNHsd chromosome 5 transferred to the ACI/SegHsd strain background
Proper citation: RRID:RGD_1566445 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=737657
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: Originally derived by Dr. Hans J. Hedrich at Versuchstierzucht, Hannover, Germany by transgressing the MHC of DA/Han rats (AV1) into LEW/Han rats for 16 backcross generations. RT1av1 haplotype is a variant to the standard a- haplotype with the difference residing in the atypical MHC class I region.
Proper citation: RRID:RGD_737657 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=728196
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: Heterozygous Gunn rats were mated with RHA/N the heterzygous offsprings of this and each following generation was backcrossed with RHA/N to get these congenics.
Proper citation: RRID:RGD_728196 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60986
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: Heston 1946 from Buffalo stock of H. Morris. To NIH in 1950 at F10. NIH Autoimmune Rat Model Repository and Development Center
Proper citation: RRID:RGD_60986 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60987
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: Milan Hypertensive Strain: Outbred Wistar rats with brother x sister mating and selection for high systolic blood pressure (Bianchi et al 1974, Barber et al, 1994).
Proper citation: RRID:RGD_60987 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=61011
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: Mutation causing diabetes mellitus in a closed colony of outbred Wistar rats at Bio-Breeding Labs, Ontario, Canada in 1974 (Chappel and Chappel 1983). To Worcester in 1977 where inbreeding began. Sublines of diabetic-prone and diabetic-resistant animals have been developed, and there are also subline differences in the incidence, age of onset, untreated survival time of diabetes, leucopenia and body weight gain which can be attributed to genetic factors (Kloting et al 1987). A detailed study of 24 inbred and two outbred lines of diabetes-prone and diabetes resistant BB rats using eight marker loci found substantial genetic variation among and some variation within some of the colonies. The 22 colonies which were apparently isogenic could be divided into four groups on the basis of the marker loci (Prins et al 1990).
Proper citation: RRID:RGD_61011 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10026
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: To N 1964 at F18+? from Maas. Developed by Broadhurst, 1954, from a commercial stock, with selection for low defecation response in an open field. A number of parallel sublines are in existence; these differ at least at the agouti and the major histocompatibility loci.
Proper citation: RRID:RGD_10026 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4139879
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: This strain was produced by injecting ZFNs targeting the sequence ctctgaaccttcaactttcagatactgatgacaatgaa into SS/JrHsdMcwi rat embryos. The resulting mutation is a 10-bp frameshift deletion in exon 6.
Proper citation: RRID:RGD_4139879 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5508371
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: This strain was produced by injecting ZFNs targeting the sequence GCCCCAGCCATGCTGTGCtatgtGACGAGGCCGGACGCGGTG into SS/JrHsdMcwi rat embryos. The resulting mutation is a 51-bp frameshift deletion in exon 1.
Proper citation: RRID:RGD_5508371 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5509997
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: This strain was produced by injecting ZFNs targeting the sequence ctctgaaccttcaactttcagatactgatgacaatgaa into SS.BN-(D13Rat20-D13Got22)/Mcwi rat embryos. The resulting mutation is an 11-bp frameshift deletion in exon 6.
Proper citation: RRID:RGD_5509997 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5687974
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: This strain was produced by injecting ZFNs targeting the sequence CTGCTCTATGACCCTGACTatgtgAAGGTGGTTCTGGGAAGAT into SS-Chr 5BN/Mcwi strain rat embryos. The resulting mutation is a 2-bp framesnift deletion in exon 2.
Proper citation: RRID:RGD_5687974 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5687992
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Proper citation: RRID:RGD_5687992 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5687987
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Proper citation: RRID:RGD_5687987 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5688006
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Proper citation: RRID:RGD_5688006 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5688002
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Proper citation: RRID:RGD_5688002 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=6893437
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: This strain was produced by injecting ZFNs targeting the sequence AGCTTCATACAGCGGCtccatgTTGCAGGGGATGGAAGTC into BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi rat embryos. The resulting mutation is a 13-bp deletion in exon 5.
Proper citation: RRID:RGD_6893437 Copy
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