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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.mdanderson.org/research/research-resources/core-facilities/proteomics-facility.html
Facility provides mass spectrometry analysis of proteins. Provides access to mass spectrometry based proteomics technologies and services including Protein Identification, Molecular Weight Determination, Quantitative Protein Analysis, Post-translational Modification Analysis, LC or LC-MS Analysis, Equipment Usage, Additional Data Analysis:Bioinformatics, statistics, pathway analysis and Assistance preparing materials for manuscripts or grants.Consultations for custom assays for other MS Services are also available.
Proper citation: University of Texas MD Anderson Cancer Center Proteomics Core Facility (RRID:SCR_017731) Copy
https://voices.uchicago.edu/ucflow/
Core offers services in cytometry and antibody technology, helps to design projects, data acquisition, analysis and/or interpretation beyond routine practices,critical drafting and/or revision of manuscript for intellectual content purposes.
Proper citation: Chicago University Cytometry and Antibody Technology Core Facility (RRID:SCR_017760) Copy
http://www.med.unc.edu/csb/unc-peptides
Core offers services for: High quality synthetic peptides, stable isotope labeled peptides, peptides with PTM and fluorescent and affinity tags, synthesis of peptide libraries. Analysis of synthetic peptides. Purification, lyophilization and aliquoting of synthetic peptides.
Proper citation: North Carolina University at Chapel Hill School of Medicine High Throughput Peptide Synthesis and Array Core Facility (RRID:SCR_017837) Copy
https://www.med.unc.edu/csb/mx/
Core provides support and infrastructure necessary to initiate and successfully complete structural biology or structural chemistry project. Offers services in Crystallization,X-Ray DiffractionData Collection,Structure Determination and Refinement.
Proper citation: North Carolina University at Chapel Hill School of Medicine Macromolecular X-Ray Crystallography Core Facility (RRID:SCR_017839) Copy
https://www.utsouthwestern.edu/labs/qlmc/
Provides access to variety of microscope modalities including laser scanning and spinning disk confocal, multiphoton, wide field deconvolution, CFP/YFP FRET, TIRF, single molecule imaging, and more. Offers customized microscopy training, advise and help with sample preparation, image quantification, and offer basic microscope maintenance. Can streamline your data handling and image visualization as well as automate your image analysis workflow through customized Fiji macros.
Proper citation: University of Texas Southwestern Medical Center Quantitative Light Microscopy Core Facility (RRID:SCR_022605) Copy
https://www.nationwidechildrens.org/research/areas-of-research/biopathology-center/about
Provides services related to biospecimen procurement, banking, processing, and distribution. Housed biospecimen collections are from biorepositories of National Cancer Institute funded Children’s Oncology Group, NRG Oncology-Columbus (formerly the GOG Tissue Bank), SWOG, Pediatric Division of Cooperative Human Tissue Network, and Biospecimen Core Resource of Center for Cancer Genomics, as well as numerous biospecimen collections sponsored by funded NCH investigators. Cooperative Human Tissue Network is one of six institutions funded by National Cancer Institutes to access to remnant human tissues for biomedical researchers throughout the United States and Canada. Offers expertise in tissue preparation and preservation to meet the research needs of basic and applied scientists.
Proper citation: Nationwide Children’s Hospital Abigail Wexner Research Institute Biopathology Center Core Facility (RRID:SCR_023260) Copy
https://health.ucdavis.edu/cancer/research/sharedresources/biostatistics.html
Provides expertise in design, analysis and reporting of cancer related studies, including basic, translational, clinical and population based research. BSR affiliated faculty and staff work with investigators from the earliest stages of study planning. The shared resource is especially committed to mentoring early career cancer researchers.
Proper citation: University of California Davis Health Biostatistics Shared Resource Core Facility (RRID:SCR_023585) Copy
https://health.ucdavis.edu/cancer/research/sharedresources/combichem.html
Provides high throughput screening platform to discover unique chemical probes against biological targets using various one bead one compound and one bead two compound combinatorial libraries.Interacts closely with resource users on optimization of the lead compounds via focused libraries and standard medicinal chemistry techniques. Provides custom synthesis of telodendrimer based micellar nanoparticle platform for efficient drug delivery.
Proper citation: University of California Davis Health Combinatorial Chemistry and Chemical Biology Shared Resource Core Facility (RRID:SCR_023584) Copy
https://health.ucdavis.edu/cancer/research/sharedresources/cmp.html
Provides services to support the development and implementation of clinical trials at UC Davis Comprehensive Cancer Center. Oversees high quality collection, processing, and analysis of clinical specimens,typically but not exclusively blood specimens, for pharmacokinetic and pharmacodynamics studies. Conducts preclinical modeling of novel anti cancer agents to test hypotheses and develop scientific rationale required for translation of laboratory concepts into clinical trials, including assessment of DM/PK/PD properties.
Proper citation: University of California Davis Health Molecular Pharmacology Shared Resource Core Facility (RRID:SCR_023588) Copy
https://med.stanford.edu/cancer/research/shared-resources/biostatistics_research_informatics.html
Core provides statistical support to SCI members by engages them on their data related needs. Specifically, BSR members assist researchers at each stage of study’s lifecycle, including project design, mid study evaluation and interpretation and reporting of results. In addition, BSR members mentor SCI investigators in research methods. BSR assists with development and review of proposed studies and planning of research related data management systems.
Proper citation: Stanford University School of Medicine Cancer Institute Biostatistics Shared Resource Core Facility (RRID:SCR_023696) Copy
https://maayanlab.cloud/drugmonizome/#/
Database with search engine for querying annotated sets of drugs and small molecules for performing drug set enrichment analysis.
Proper citation: Drugmonizome (RRID:SCR_024821) Copy
https://github.com/broadinstitute/ichorCNA
Software tool that quantifies tumor content in cfDNA from 0.1× coverage whole-genome sequencing data without prior knowledge of tumor mutations. Used to simultaneously segment genome, predict large scale copy number alterations, and estimate tumor fraction of ultra low pass whole genome sequencing sample.
Proper citation: ichorCNA (RRID:SCR_024768) Copy
https://www.med.unc.edu/microscopy/
Core provides training, assistance and services in light microscopy, electron microscopy and image analysis. UNC core facility that is part of Department of Pathology and Laboratory Medicine, and are light microscopy core for Lineberger Comprehensive Cancer Center.
Proper citation: University of North Carolina at Chapel Hill Microscopy Services Laboratory Core Facility (RRID:SCR_017913) Copy
https://dtcore.northwestern.edu/
Core evaluates therapeutic agents and diagnostics, as well as existing therapeutics being considered for novel uses, through continued development and deployment of relevant animal models and in vitro cell lines and tissue models. Provides services to investigators to suit many needs, including those who may lack laboratory facilities and/or expertise for conducting experiments associated with preclinical therapeutic hypothesis testing.Services include Proliferation and Apoptosis Assays, Therapy-Response Experiments, Exploratory PK and Tox, Device Implantation and Monitoring,PDX Models,Immunization.
Proper citation: Northwestern University Developmental Therapeutics Core Facility (RRID:SCR_017948) Copy
http://proteomics.northwestern.edu/collaborate
Core offers multiple types of experiments from simple protein identification to protein quantitation. Performs traditional bottom-up proteomics, where proteins are digested with enzyme prior to analysis and intact, top-down proteomics analyses. Services include proteins identification after in-gel or in-solution digestion, top-down mass spectrometry to preserve post-translationally modified forms of proteins present in vivo by measuring them intact, IP-MS Pulldown,BioID service to identify target of biotin ligase that has been tagged onto their protein via traditional cloning methods,Untargeted Quantitative Peptide Proteomics,Targeted Quantitative Peptide Proteomics,Epiproteomic Histone Modification Panel A,Epiproteomic Histone Modification Panel B,Untargeted Metabolomics,Phosphoproteomics,PTM Scan,ChIP-MS.
Proper citation: Northwestern University Proteomics Core Facility (RRID:SCR_017945) Copy
http://www.med.nyu.edu/ocs/cytometry-and-cell-sorting-core
Facility provides cytometry and cell sorting services. Services include immunophenotyping, cell cycle analysis, and intracellular fluorophore detection. Services can be tailored to research needs, certified cytometrists are available to help plan experiments. Offers online and hands-on training in use of cell analyzers and analysis software.
Proper citation: New York University School of Medicine Langone Cytometry and Cell Sorting Core Facility (RRID:SCR_018827) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/cytometry-cell-sorting-laboratory
Provides access to flow cytometry and cell sorting technologies and instruments. If your research requires cytometric analysis, instruments acquire optical measurements using different lasers to detect fluorophores with high level of precision.
Proper citation: New York University Grossman School of Medicine Cytometry and Cell Sorting Laboratory Core Facility (RRID:SCR_019179) Copy
Provides services and expertise to unlock genome editing tools to advance your research. Routinely generates new genome edited models, particularly mouse, rats, swine, and cell lines, as well as supports in vivo editing, novel preclinical therapeutic strategies, pooled lentiCRISPR screening, and other applications.
Proper citation: University of Wisconsin-Madison Advanced Genome Editing Laboratory (RRID:SCR_021070) Copy
Provides advanced instrumentation as well as high level technical and scientific expertise in multi dimensional Flow Cytometry and Cell Sorting, to facilitate science, improve the quality, and advance the scope of MSK research.
Proper citation: Memorial Sloan Kettering Cancer Center Flow Cytometry Core Facility (RRID:SCR_021105) Copy
https://cancer.dartmouth.edu/scientists-researchers/mouse-modeling
Supports generation and utilization of genetically modified mice, design and production of genetic constructs with methods including yeast and E.coli recombineering, ES cell targeting (transfection, drug selection, and expansion). Produces transgenic mice: DNA injections into oocytes, ES cell injections into blastocysts.Provides humanized immune system mouse models.Offers start to finish experiment services to assist your many needs, please ask for more info.Other services include animal husbandry, IP and IV injections, blood drawing, necropsy and surgeries- embryo transfers, ovariectomy, vasectomy, tumor removal.
Proper citation: Dartmouth Geisel School of Medicine Mouse Modeling Core Facility (RRID:SCR_021284) Copy
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