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http://harvard.eagle-i.net/i/0000012e-0220-1cee-b2b9-4d8780000000

Core facility that provides the following services: Illumina Gene Expression, Affymetrix gene expression. The Partners HealthCare Center for Personalized Genetic Medicine Microarray Facility is a full service facility dedicated to providing analysis for DNA or RNA samples. We provide support for high density microarrays to the Harvard Partners research community, including Harvard medical School, hospitals in the Partners Healthcare network, investigators in the Dana-Farber/Harvard Cancer Center, and the Harvard School of Public Health. Our services are open to both the PHS and non-PHS community.

Proper citation: Harvard PCPGM Microarray Facility (RRID:SCR_009860) Copy   

•   Source: SciCrunch Registry

http://msm.eagle-i.net/i/0000012b-00c2-775d-353c-df7f80000000

Core facility that provides the following services: Basic animal care service, Clinical and health monitoring service, Humane euthanasia service, Animal disposal service, Animal quarantine service, Necropsy and diagnostics service, Animal vaccination service, Animal use consultation service, Breeding service, Animal sample collection service, Assistance with minor surgery, Animal tattooing service.

Access to CLAR facilities is restricted to authorized investigators with CLAR and IACUC approval. No individuals may enter the facilities without this CLAR/IACUC authorization. Since its inception, the Center for Laboratory Animal Resources (CLAR) has centralized most research and teaching animal care for the Atlanta University Center consortium. Our purpose is to provide total animal care services as needed to all academic and/or research faculty and staff affiliated with any one of the member institutions of the Atlanta University Center (AUC).

Proper citation: MSM Center of Laboratory Animal Resources (RRID:SCR_009935) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012b-00bc-09f9-3984-bcfb80000000

Core facility that provides the following services: Equipment access. Jackson State University Visualization Laboratory is part of the Trent Lott Geospatial and Visualization Research Center (TLGVRC). It is a research laboratory specializing in virtual reality and real-time interactive computer graphics. The mission of the visualization laboratory is to ensure highly advanced technical and theoretical visualization support to scientific research. Our goal is to provide a well-integrated and diverse scientific visualization knowledge and tools to the students, staff, and faculty.

Proper citation: JSU Visualization Laboratory (RRID:SCR_009899) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012b-00bc-6e5c-3984-bcfb80000000

Core facility that provides the following services: Statistical design and analysis, Data collection and management service. The mission of the Research Centers in Minority Institutions Translational Research Network (RTRN) Data Coordinating Center (DCC)is to provide the technology infrastructure and data management resources to facilitate inter-institutional collaborations, including community engagement, information and data sharing, and dissemination across the diverse RCMI communities to improve health outcomes, especially for underserved populations.

Proper citation: JSU RCMI Translational Research Data Coordinating Center (RRID:SCR_009897) Copy   

•   Source: SciCrunch Registry

http://msm.eagle-i.net/i/0000012f-7421-42f6-38fa-ed3d80000000

Core facility that provides the following services: Gene variations analysis, Genotyping service.

The Human Genotyping Lab assists investigators to apply the genomic technologies to population-based research. The strategic plan is to create a link between basic science, clinical investigation and population-based research by integrating genomic sciences into our research program. The central hypothesis is that health disparities are related in part to ethnicity-specific DNA variants in critical genes that influence the susceptibility to common diseases. Morehouse School of Medicine has a longstanding interest on the studies of ethnic disparities and a longstanding strength on community outreach to underserved minority populations. Accordingly, the major objective of the MSM Human Genome Core Laboratory is to enhance the research capacity on these sample cohorts and upgrade our research to the molecular genetic level based on cutting-edge genomic technologies.

Proper citation: MSM Gene Variation Core Laboratory (RRID:SCR_009930) Copy   

•   Source: SciCrunch Registry

http://xula.eagle-i.net/i/00000135-0c6f-559b-77e4-a45080000000

Core facility that provides the following services: Tissue procurement, Quality assurance/histopathologic review, Biospecimen storage. The Louisiana Cancer Research Consortium (LCRC) Tissue Procurement and Biospecimen Core Facility (TPBCF) is a part of the infrastructure to support the conduct of basic and clinical research for members of the LCRC. The goal of the repository is to support LCRC programmatic research in order to further improve our understanding of those molecular factors that contribute to cancer and that may lead to prevention, early detection, and cure. The mission of the Biospecimen Core is to collect high quality samples of normal and diseased human material (e.g., whole blood, cellular blood components, plasma, urine, body fluids, DNA, and tumor tissue and cells) with appropriate clinical data and to make this material available to qualified researchers at Louisiana Cancer Research Consortium while ensuring the informed consent, safety, donor anonymity, and all regulatory safeguards are in place.

Proper citation: LCRC Biospecimen Core (RRID:SCR_009895) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012b-d4be-703e-3bf4-a80880000000

Core facility that provides the following services: Computational access service. The Computational Modeling Core is part of the CREST Interdisclipinary Center for Nanotoxicity, aka the Center for Applied Computational Sciences.

Proper citation: JSU Computational Modeling Core Laboratory (RRID:SCR_009891) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a0c0-39f6-55da-381e80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30, 2023. Core facility that provides the following services: Microscopy consultation services, Technical microscopy service, Microscopy training services, Conventional immunofluorescence microscopy service, Confocal microscopy service, Live-cell imaging service, Conventional electron microscopy service, EM immunogold labeling service, Tissue sectioning service, Tissue fixation, Computer based image analysis and quantification.

Proper citation: MGH PMB Microscopy Core (RRID:SCR_009928) Copy   

•   Source: SciCrunch Registry

http://msm.eagle-i.net/i/0000012e-5936-2dc1-0e5d-6ffe80000000

Core facility that provides the following services: Fragment (microsatellite) analysis service, Enumeration of polymorphisms (SNPs), DNA sequencing.

The DNA Sequencing Lab is the longest-established lab in the Gene Profiling Core, providing DNA sequence analysis to investigators involved in research utilizing molecular biology techniques. The lab uses capillary electrophoresis sequencing technology and is built around the ABI 3130xl Gene Analyzer (16-capillary) and associated software for DNA sequence analysis.

Proper citation: MSM DNA Sequencing Laboratory (RRID:SCR_009929) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-edef-166a-b2b9-4d8780000000

Core facility that provides the following services: Magnetic Resonance Spectroscopy Service, Magnetic Resonance Imaging Service.

The Musculoskeletal Imaging Research Core (MIRC) offers specialized imaging techniques including quantitative computed tomography (QCT), magnetic resonance (MR) spectroscopy of muscle and high-resolution soft tissue MR imaging. QCT is a technique widely employed for studies evaluating body composition and bone mineral density. MR spectroscopy is a technique that allows non-invasive quantification of metabolites in human tissues.

Proper citation: MGH Musculoskeletal Imaging Research Core (RRID:SCR_009926) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-2508-4b59-43fb-601a80000000

The core laboratory facility has the necessary equipment to provide each study with the initial specimen processing and handling required for shipping to a reference laboratory and for storage and maintenance at a sample repository. Laboratory procedures provided by the core laboratory are intended for research use only,and not for diagnostic; it may provide other specialized services for specific protocols on a case by case basis.

Proper citation: Puerto Rico Clinical and Translational Research Consortium Core Laboratory (RRID:SCR_009922) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5961-f9b9-55da-381e80000000

Core facility that provides the following services: Flow cytometric analysis and cell sorting. The cell sorting and analysis lab provides access to the most sophisticated flow cytometers presently available. The core is able to analyze and physically separate cells based upon features detectable with fluorescently labeled monoclonal antibodies. This facilities has two locations: the Simches site and the Charlestown Navy Yard (CNY) site.

Proper citation: MGH Flow Cytometry Core Facility (RRID:SCR_009887) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-b800-0461-d807-77a880000000

Core facility that provides the following services: Fresh hepatocytes in suspension, Plated hepatocytes, Cryopreserved hepatocytes, Custom hepatocyte isolations, Decellularized whole rat livers. The mission of the Cell Resource Core (CRC) is to provide high quality primary cells and tissues to researchers reliably and affordably. Leveraging a new MGH technology that significantly increases the viable yield of high quality hepatocytes from human and animal donor livers, we are initially offering hepatocytes to the research community.

Proper citation: MGH Cell Tissue and Organ Resource Core (RRID:SCR_009920) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012a-2505-c6a1-b307-36d480000000

Core facility that provides the following services: Statistical design and analysis. Applied statistical methodologies and data analysis techniques are critical under-girding factors in research and knowledge advancement. Appropriate experimental design lays foundation of sound research plans; sample size determines the power of significance and efficient utilization of scarce resources; and adequate data analysis generate results that are valid and true representative of the population in question. The Biostatistical Support Unit (BSU) provides statistical services and research support to RCMI investigators, other faculty, as well as to graduate and undergraduate students.(http://www.jsums.edu/cset/rcmi/bsu.htm)

Proper citation: JSU BSU-RCMI Biostatistics Core Laboratory (RRID:SCR_009888) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-9652-3f24-55da-381e80000000

Core facility that provides the following services: Double- and triple-labeling experiments, Acquisition of high-resolution images: 2048 x 2048 pixels, Single molecule visualization, allowing dynamic observation and functional analyses of both in vivo and living cells, Total internal reflection fluorescence experiments (TIRF).

This Core consists of a Zeiss LSM 5 Pascal laser confocal microscope with a Zeiss RGB vario laser module and Nikon C1 Confocal/TIRF System with 3 PMT. A Zeiss Axiovert 200 fully motorized light microscope is available with fluorescence, bright-field, phase-contrast and Nomarski (DIC) capabilities. Image acquisition and analyses are performed using Zeiss LSM 5 Pascal Confocal Microscopy Software (Release 3.2) on 2 workstations. Zeiss Physiology software is available also. Live cell imaging is available using a Zeiss temperature controller with custom chamber and heating stage. The Nikon C1 Confocal/TIRF System fully motorized Nikon Eclipse Ti microscope is available with fluorescence, bright-field and TIRF capabilities. Imaging acquisition and analyses are performed using EZ-C1 and NIC-Elements Software.

Proper citation: MGH Confocal Microscope Core (RRID:SCR_009921) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012b-00bc-22cd-3984-bcfb80000000

Core facility that provides the following services: Animal husbandry service. The Animal Care Facility (ACF) is one of the essential units of support and service to the biomedical research at Jackson State University. Its long term goal is to develop a state-of-the-art infrastructure as well as to provide technical and logistic support to RCMI investigators and other JSU faculty and students to conduct a high quality of animal research, in compliance with the guidelines and policies set for by accrediting and regulatory agencies, especially as they relate to IACUC protocol development, animal husbandry, food and water supply, veterinary care, quarantine and euthanasia, sanitation procedures, environmental monitoring, and record keeping. ACF provides accommodation for long-term storage of animals and maintains them in accordance with and in compliance with the PHS Policy on the Humane Care and Use of Laboratory Animals and the Animal Welfare Act, as described in the 2002 Guide for the Care and Use of Laboratory Animals.

Proper citation: JSU Animal Core Facility (RRID:SCR_009886) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a183-b053-55da-381e80000000

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core provides the following services: Trypsinization service. Core provides a full range of services to the Joslin research community spanning from consulting on proteomic experimental design to data acquisition and analysis. The core operates a high throughput nano liquid chromatography, nanospray ionization, LTQ 2D ion trap tandem mass spectrometer system. This system is used for two routine proteomic services, including Targeted Protein Analysis and Protein Inventory. Targeted Protein Analysis is used to identify and provide in depth characterization, including phosphorylation site mapping, of proteins isolate by SDS-PAGE. Protein Inventory is used to catalogue the protein composition in a sample separated by 1D SDS-PAGE. This service provides information on protein identification, molecular weight (gel mobility), and spectral/peptide counts, a semi-quantitative measure of protein abundance. In addition, the Core works with investigators on specialized analyses involving tandem mass spectrometry, including specialized enzymatic digests (peptide preparation), selective reaction monitoring (SRM), and targeted peptide detection. The Proteomic Core provides in house database resources and analysis tools and also coordinates with Joslin's Bioinformatics Core to provide further assistance with data organization and interpretation. The Core hosts seminars on proteomic topics and provides instruction on practical and theoretical aspects of mass spectrometry-based proteomics.

Proper citation: Joslin Diabets Center Proteomics Core Facility (RRID:SCR_009883) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-97ab-90a0-55da-381e80000000

Core facility that provides the following services: Custom mutation detection and DNA sequencing services, Custom genotyping service.

This resource provides custom genotyping (microsatellite, SNP, other) in human and mouse, mutation detection/DNA sequencing, dosage analysis and related services to further the CHGR mission of promoting the use of genetic strategies in basic and clinical research.

Proper citation: MGH CHGR Genotyping Resource (RRID:SCR_009919) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-ee0d-d869-b2b9-4d8780000000

Core facility that provides the following services: DNA sequencing service, High volume DNA sequencing, Plasmid verification and primer walking service, PCR purification service, Microsatellite analysis.

The DNA Sequencing Core at the Massachusetts General Hospital functions both as a small-scale sequencing facility and a high-throughput center for large-scale sequencing projects.

Proper citation: MGH CCIB DNA Sequencing Core (RRID:SCR_009915) Copy   

•   Source: SciCrunch Registry

https://hddc.hms.harvard.edu/core-b

Core facility that provides service for paraffin embedding, sectioning, staining, and frozen sectioning; shared equipment and service for confocal, widefield, photodocumentation, electron microscopy, and digital image processing; and an immunostaining service.

Proper citation: Harvard Digestive Diseases Center Biomedical CORE B: Microscopy and Histopathology (RRID:SCR_009836) Copy   

•   Source: SciCrunch Registry