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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Functional Dyspepsia Treatment Trial
 
Resource Report
Resource Website
Functional Dyspepsia Treatment Trial (RRID:SCR_006691) FDTT clinical trial, resource Multi-center, randomized, placebo-controlled trial evaluating the tricyclic antidepressant, amitriptyline and the selective serotonin reuptake inhibitor (SSRI), escitalopram to placebo in patients with functional dyspepsia. The purpose of this study is to determine whether amitriptyline and escitalopram are more efficacious than placebo in relief of the symptoms of functional dyspepsia, adjusting for psychological and psychiatric co-morbidities. antidepressant, amitriptyline, selective serotonin reuptake inhibitor, escitalopram, placebo is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: ClinicalTrials.gov
Functional dyspepsia NIDDK PMID:22343090 nlx_152830 SCR_006691 Antidepressant Therapy for Functional Dyspepsia, Functional Dyspepsia Treatment Trial (FDTT) 2026-02-14 02:07:23 0
Maryland Genetics of Interstitial Cystitis
 
Resource Report
Resource Website
Maryland Genetics of Interstitial Cystitis (RRID:SCR_006992) MaGIC clinical trial, resource Clinical study that investigated several hundred families with two or more blood relatives with interstitial cystitis in order to understand the molecular genetic basis of this condition. The study sought to find changes in genes that are found far more commonly in family members who have interstitial cystitis than in those who do not have the disease. Identifying these genes should lead to a better understanding of the cause of interstitial cystitis. This is a national study which is conducted by telephone and mail, and in which participants could participate entirely from their home. male, female, adolescent, adult human, genetics, risk factor, family history, bladder, pain, observational is related to: NIDDK Information Network (dkNET)
has parent organization: ClinicalTrials.gov
has parent organization: University of Maryland School of Medicine; Maryland; USA
Interstitial cystitis NIDDK nlx_152843 http://icresearch.umaryland.edu/magic.aspx SCR_006992 Maryland Genetics of Interstitial Cystitis (MaGIC) 2026-02-14 02:07:53 0
High-dose Ursodiol Therapy of Primary Sclerosing Cholangitis
 
Resource Report
Resource Website
High-dose Ursodiol Therapy of Primary Sclerosing Cholangitis (RRID:SCR_006772) HUSC clinical trial, resource Multi-center, placebo-controlled trial of ursodiol in primary sclerosing cholangitis (PSC). A total of 150 patients with previously untreated PSC without cirrhosis were randomly assigned to receive high doses of ursodiol (20-25 mg/kg/day) or placebo for two years. Patients underwent medical evaluation, endoscopic retrograde cholangiography, and liver biopsy before randomization and again at two-year intervals. The endpoints of therapy were progression of hepatic fibrosis, liver decompensation, liver transplantation, or death. The treatment phase of the study was stopped for futility in June 2008; however, patients continue to be followed. Ongoing mechanistic studies are underway. treatment, placebo, ursodeoxycholic acid, intervention, randomized, adult human, male, female is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: ClinicalTrials.gov
Primary Sclerosing Cholangitis NIDDK PMID:19585548 nlx_152836 SCR_006772 Trial of High-dose Urso in Primary Sclerosing Cholangitis, High-dose Ursodiol Therapy of Primary Sclerosing Cholangitis (HUSC), Multicentered Randomized Trial of High-dose Urso in Primary Sclerosing Cholangitis 2026-02-14 02:07:53 0
Efficacy and Mechanisms of Glutamine Dipeptide in the Surgical Intensive Care Unit
 
Resource Report
Resource Website
Efficacy and Mechanisms of Glutamine Dipeptide in the Surgical Intensive Care Unit (RRID:SCR_006806) GLND clinical trial, resource Multi-center, double-blind, placebo-controlled, intent-to-treat Phase III trial, designed to determine the effect of parenteral glutamine (GLN) dipeptide on important clinical outcomes in patients requiring surgical intensive care unit (SICU) care and parenteral nutrition (PN) after cardiac, vascular, or intestinal surgery. Patients who required PN and SICU care will receive either standard glutamine (GLN)-free PN (STD-PN) or isocaloric, isonitrogenous alanyl-glutamine dipeptide (AG)-PN until enteral feedings are established. The study will determine whether AG-PN decreases hospital mortality, nosocomial infection and other important indices of morbidity and will obtain mechanistically relevant observational data in the subjects on whether AG-PN a) increases serial blood concentrations of glutathione (GSH), heat shock proteins (HSP)-70 and -27, and glutamine; b) decreases the serum presence of the bacterial products flagellin and lipopolysaccharide (LPS) and the adaptive immune response to these mediators; and c) improves key indices of innate and adaptive immunity. parenteral nutrition, glutamine, glutamine dipeptide, clinical, outcome, adult human, mortality, nosocomial infection, immune cell function, hospital morbidity, morbidity, intensive care is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: Emory University; Georgia; USA
Critical illness NIDDK U01DK069322 PMID:18596310 nlx_152823 http://www.sph.emory.edu/GLND SCR_006806 Phase III Study on the Efficacy of Glutamine Dipeptide-Supplemented Parenteral Nutrition in Surgical ICU Patients, Efficacy and Mechanisms of GLN Dipeptide in the SICU, Efficacy and Mechanisms of GLN Dipeptide in the SICU (GLND), GLND trial 2026-02-14 02:07:23 0
Diabetes Control and Complications Trial
 
Resource Report
Resource Website
Diabetes Control and Complications Trial (RRID:SCR_006805) DCCT data or information resource, clinical trial, database, resource Clinical study that showed that keeping blood glucose levels as close to normal as possible slows the onset and progression of eye, kidney, and nerve diseases caused by diabetes. EDIC is a follow-up study of people who participated in DCCT. The DCCT involved 1,441 volunteers, ages 13 to 39, with type 1 diabetes and 29 medical centers in the United States and Canada. Volunteers had to have had diabetes for at least 1 year but no longer than 15 years. They also were required to have no, or only early signs of, diabetic eye disease. The study compared the effects of standard control of blood glucose versus intensive control on the complications of diabetes. Intensive control meant keeping hemoglobin A1C levels as close as possible to the normal value of 6 percent or less. The A1C blood test reflects a person''''s average blood glucose over the last 2 to 3 months. Volunteers were randomly assigned to each treatment group. DCCT Study Findings * Intensive blood glucose control reduces risk of ** eye disease: 76% reduced risk ** kidney disease: 50% reduced risk ** nerve disease: 60% reduced risk When the DCCT ended, researchers continued to study more than 90 percent of participants. The follow-up study, called Epidemiology of Diabetes Interventions and Complications (EDIC), is assessing the incidence and predictors of cardiovascular disease events such as heart attack, stroke, or needed heart surgery, as well as diabetic complications related to the eye, kidney, and nerves. The EDIC study is also examining the impact of intensive control versus standard control on quality of life. Another objective is to look at the cost-effectiveness of intensive control. EDIC Study Findings * Intensive blood glucose control reduces risk of ** any cardiovascular disease event: 42% reduced risk ** nonfatal heart attack, stroke, or death from cardiovascular causes: 57% reduced risk blood glucose, adolescent, young human, middle adult human, longitudinal, eye disease, kidney disease, nerve disease, cardiovascular disease, heart attack, stroke, blood pressure, blood lipid, complication is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Central Repository
is related to: Epidemiology of Diabetes Interventions and Complications
is related to: Epidemiology of Diabetes Interventions and Complications
is related to: NIDDK Information Network (dkNET)
has parent organization: National Diabetes Information Clearinghouse
Type 1 diabetes, Diabetes NIDDK nlx_152798 SCR_006805 DCCT and EDIC: The Diabetes Control and Complications Trial and Follow-up Study 2026-02-14 02:07:57 0
Frequent Hemodialysis Network Nocturnal Trial
 
Resource Report
Resource Website
Frequent Hemodialysis Network Nocturnal Trial (RRID:SCR_007014) FHN Nocturnal Trial clinical trial, resource Randomized controlled clinical trial where subjects will be randomized to conventional hemodialysis delivered three days per week home arm or to the six times per week nocturnal home hemodialysis arm which will follow any dialysis prescription provided their prescribed standardized Kt/V is at least 4.0 and treatment time is at least 6.0 hours, six times per week. Subjects were recruited from dialysis units associated with designated Clinical Centers in the U.S. and Canada and followed for 12 months. Primary Outcome Measures: * composite of 12 month mortality and the change over 12 months in left ventricular mass by cine-MRI, * a composite of 12 month mortality and the change over 12 months in the SF-36 RAND physical health composite Secondary Outcome Measures: * cardiovascular structure/funct (change in LV mass over 12 mos), health-related QoL/phys funct (change over 12 mos in PHC), * depression / dis burden (change over 12 mos in Beck Depression Inv.), nutrition (change over 12 mos in serum albumin, cognitive funct (change over 12 mos in TrailMaking Test B), mineral metabolism (change over 12 mos in aveg pre-dialysis serum phosphorus), * clin events (rate of non-access hospital or death * hypertension, anemia hemodialysis, home, adult human, kidney, kidney disease is listed by: ClinicalTrials.gov
is related to: Frequent Hemodialysis Network Daily Trial
is related to: NIDDK Information Network (dkNET)
has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
End Stage Renal Disease, Hemodialysis NIDDK PMID:21775973
PMID:17164834
PMID:17699439
nlx_152829 SCR_007014 Frequent Hemodialysis Network (FHN) Nocturnal Trial, Frequent Hemodialysis Network: Nocturnal Trial 2026-02-14 02:07:23 0
University of Chicago Digestive Diseases Research Core Center Tissue Engineering and Cell Models Core
 
Resource Report
Resource Website
1+ mentions
University of Chicago Digestive Diseases Research Core Center Tissue Engineering and Cell Models Core (RRID:SCR_015604) TECM biomaterial supply resource, material resource Core that provides services such as a repository for intestinal cell lines, Tissue Engineering Models, experimental materials, and supplies for digestive disease research. TECM, tissue engineering, cell models is listed by: NIDDK Information Network (dkNET)
has parent organization: University of Chicago Digestive Diseases Research Core Center
is organization facet of: University of Chicago Digestive Diseases Research Core Center
digestive disease NIDDK P30 DK042086 Available to the research community SCR_015604 2026-02-14 02:07:18 1
Einstein-Mount Sinai Diabetes Research Center Translational Research Core Facility
 
Resource Report
Resource Website
Einstein-Mount Sinai Diabetes Research Center Translational Research Core Facility (RRID:SCR_015068) core facility, access service resource, service resource Core services include consultation, technical support and training and mentoring in clinical and translational research methods that are specifically applicable to diabetes, its complications and related metabolic disorders. Personel provides expertise in first-in-human and mechanistic studies in integrative physiology, in clinical trials of diabetes and obesity, and in application of new technologies. translational research, data interpretation, diabetes research is listed by: NIDDK Information Network (dkNET)
is listed by: ABRF CoreMarketplace
has parent organization: Einstein-Mount Sinai Diabetes Research Center
is organization facet of: Einstein-Mount Sinai Diabetes Research Center
Diabetes New York Obesity Research Center ;
Center for the Study of Diabetic Complications ;
Montefiore Clinical Diabetes Center ;
NIDDK P30DK020541
Open ABRF_2861 https://coremarketplace.org/?FacilityID=2861&citation=1 http://www.einstein.yu.edu/centers/diabetes-research/research-areas/biomedical-cores/translational-research-core/ SCR_015068 Einstein-Mount Sinai Diabetes Research Center Translational Research Core 2026-02-14 02:07:58 0
University of California San Francisco Diabetes Research Center Mouse Metabolism Core
 
Resource Report
Resource Website
University of California San Francisco Diabetes Research Center Mouse Metabolism Core (RRID:SCR_015101) core facility, access service resource, service resource, resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 10,2024. Core which provides technical support for UCSF investigators to conduct metabolic studies using a 12-chambered Comprehensive Lab Animal Monitoring System (CLAMS), an EchoMRI, and Dual energy X-ray absorptiometry, which together allow measurement of food intake, water intake, motor activities, core temperature, and body composition in live mice. It also helps to identify emerging technologies that will enhance multiple research programs and coordinates the acquisition and maintenance of those facilities. mouse metabolism, obesity, metabolic diseases is listed by: NIDDK Information Network (dkNET)
has parent organization: University of California at San Francisco; California; USA
has parent organization: University of California San Francisco Diabetes Research Center
is organization facet of: University of California San Francisco Diabetes Research Center
Diabetes NIDDK P30DK063720 THIS RESOURCE IS NO LONGER IN SERVICE http://drc.ucsf.edu/mouse-metabolism-core SCR_015101 2026-02-14 02:08:25 0
Boston Area Diabetes Endocrinology Research Center Cell Biology and Morphology Core Facility
 
Resource Report
Resource Website
Boston Area Diabetes Endocrinology Research Center Cell Biology and Morphology Core Facility (RRID:SCR_015069) core facility, access service resource, service resource Services provided include tissue preparation, embedding and sectioning for electron microscopy, use of electron microscope and photography of thin sections, immunogold staining for electron microscopy, preparation and incubation of samples (cells and tissues) for immunofluorescence microscopy, confocal microscopy and digital imaging. microscopy, immunofluorescence, immunogold, morphology, confocal microscopy, electron microscopy, digital imaging, is listed by: NIDDK Information Network (dkNET)
is listed by: ABRF CoreMarketplace
is organization facet of: Boston Area Diabetes Endocrinology Research Center
Diabetes NIDDK P30DK057521 Restricted ABRF_2860 https://coremarketplace.org/?FacilityID=2860&citation=1 http://www.baderc.org/cores/CBMCore.html SCR_015069 Boston Area Diabetes Endocrinology Research Center Cell Biology and Morphology 2026-02-14 02:08:34 0
University of California San Francisco Diabetes Research Center Islet Production Core Facility
 
Resource Report
Resource Website
University of California San Francisco Diabetes Research Center Islet Production Core Facility (RRID:SCR_015106) core facility, access service resource, service resource Core that enables clinical and basic research that analyzes the function of isolated pancreatic islets. It coordinates and delivers purified human islets to investigators when research need matches the availability of a human pancreas. islet isolation, pancreatic islets has parent organization: University of California at San Francisco; California; USA
has parent organization: University of California San Francisco Diabetes Research Center
is organization facet of: University of California San Francisco Diabetes Research Center
Diabetes NIDDK P30DK063720 Restricted http://drc.ucsf.edu/islet-production-core SCR_015106 2026-02-14 02:07:53 0
University of California San Francisco Diabetes Research Center Microscopy Core Facility
 
Resource Report
Resource Website
University of California San Francisco Diabetes Research Center Microscopy Core Facility (RRID:SCR_015103) core facility, access service resource, service resource Core that consolidates, enhances and disseminates Diabetes Center resources and expertise in tissue and cell imaging technologies. Confocal fluorescence, widefield fluorescence, high throughput fluorescence and brightfield microscopes are available directly within the DRC Microscopy Core. Image quantification and analysis is performed at dedicated workstations. tissue imaging, cell imaging, fluorescence, brightfield microscopes, microscopy is listed by: NIDDK Information Network (dkNET)
has parent organization: University of California at San Francisco; California; USA
has parent organization: University of California San Francisco Diabetes Research Center
is organization facet of: University of California San Francisco Diabetes Research Center
Diabetes NIDDK P30DK063720 Restricted http://drc.ucsf.edu/microscopy-core SCR_015103 , DRC Microscopy Core 2026-02-14 02:07:59 0
University of California San Francisco Diabetes Research Center Lentiviral RNAi Core Facility
 
Resource Report
Resource Website
University of California San Francisco Diabetes Research Center Lentiviral RNAi Core Facility (RRID:SCR_015104) core facility, access service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 5,2024. Core that provides reagents, equipment, training, supervision, and monitoring of investigators wishing to ensure the proper compliance with biosafety containment required for lentiviral-based research, lentiviral preparation services for investigators, and education on RNAi experimentation, through the lentiviral core website, and through protocols available at the facility. lentivirus, RNA interference, short hairpin RNAs, shRNA is listed by: NIDDK Information Network (dkNET)
has parent organization: University of California at San Francisco; California; USA
has parent organization: University of California San Francisco Diabetes Research Center
is organization facet of: University of California San Francisco Diabetes Research Center
Diabetes NIDDK P30DK063720 THIS RESOURCE IS NO LONGER IN SERVICE SCR_015104 2026-02-14 02:08:34 0
Boston Area Diabetes Endocrinology Research Center Molecular Biology
 
Resource Report
Resource Website
Boston Area Diabetes Endocrinology Research Center Molecular Biology (RRID:SCR_015079) core facility, access service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core that provides services for DNA sequencing and oligonucleotide synthesis, as well as support for projects that require research laboratory automation, such as siRNA screens and transcript abundance profiling. It also offers experimental design and advice for automation and high throughput screening of siRNA collections based on the Ambion siRNA collection. DNA sequencing, siRNA collection, research laboratory automation is listed by: NIDDK Information Network (dkNET)
has parent organization: Boston Area Diabetes Endocrinology Research Center
is organization facet of: Boston Area Diabetes Endocrinology Research Center
Diabetes NIDDK P30DK057521 THIS RESOURCE IS NO LONGER IN SERVICE SCR_015079 2026-02-14 02:07:58 0
University of Alabama at Birmingham Diabetes Research Center Animal Physiology Core Facility
 
Resource Report
Resource Website
University of Alabama at Birmingham Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015110) core facility, access service resource, service resource Core that provides diabetes researches with diabetes related phenotyping in small animal models. Their services offered include the assessment of body composition, energy balance, glucose homeostasis, cardiovascular assessment, imaging, and transgenic animals models. ABRF, animal physiology, phenotyping, transgenetics, diabetes, phenotyping, small animal models, assessment of body composition, energy balance, glucose homeostasis, transgenic animals models, is listed by: NIDDK Information Network (dkNET)
is listed by: ABRF CoreMarketplace
has parent organization: University of Alabama at Birmingham; Alabama; USA
has parent organization: University of Alabama at Birmingham Diabetes Research Center
is organization facet of: University of Alabama at Birmingham Diabetes Research Center
Diabetes NIDDK DK079626 Open ABRF_2971 https://coremarketplace.org/?FacilityID=2971&citation=1 SCR_015110 Animal Physiology Core 2026-02-14 02:08:34 0
Columbia Diabetes Research Center Flow Cytometry and Cell Sorting Core Facility
 
Resource Report
Resource Website
Columbia Diabetes Research Center Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_015078) core facility, access service resource, service resource Core which assists investigators to quantify and phenotypically characterize cell populations that contribute to the metabolic, immunologic and developmental programs of diabetes and its complications; and to purify populations of cells of relevance to diabetes and its complications. cytometry, flow cytometry, cell sorting, diabetes is listed by: NIDDK Information Network (dkNET)
is listed by: ABRF CoreMarketplace
has parent organization: Columbia University; New York; USA
is organization facet of: Columbia Diabetes Research Center
Diabetes NIDDK P30DK063608 ABRF_2857 https://coremarketplace.org/?FacilityID=2857&citation=1 https://www.derc.cumc.columbia.edu/core-facilities-and-services/flow-cyometry-and-cell-sorting-core SCR_015078 Columbia Diabetes Research Center Flow Cytometry and Cell Sorting Core 2026-02-14 02:08:24 0
Michigan Diabetes Research Center Administrative Core Facility
 
Resource Report
Resource Website
Michigan Diabetes Research Center Administrative Core Facility (RRID:SCR_015115) MDRC core facility, access service resource, service resource Administration Core of the Michigan Diabetes Research Center (MDRC) provides leadership, infrastructure, and resources to support and enhance diabetes research, including the translation of scientific discoveries from bench to bedside. Establishes, promotes, and enhances multidisciplinary and collaborative basic biomedical and clinical research among member investigators studying diabetes, its complications, and related endocrine and metabolic disorders. basic and clinical research related to diabetes, provides core services, fosters interdisciplinary collaborations, has parent organization: University of Michigan; Ann Arbor; USA
is organization facet of: Michigan Diabetes Research Center
Diabetes NIDDK P30DK020572 http://diabetesresearch.med.umich.edu/Core_MDRC_Admin.php SCR_015115 , Michigan Diabetes Research Center Administrative Core, MDRC Administrative Core 2026-02-14 02:07:59 0
Boston Area Diabetes Endocrinology Research Center Pancreatic Islet
 
Resource Report
Resource Website
Boston Area Diabetes Endocrinology Research Center Pancreatic Islet (RRID:SCR_015073) core facility, access service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 23,2024.Core which provides islets to the local diabetes research community in the Boston area. They collaborate with researchers nationally to provide nonhuman primate (NHP) islets for research. islet, islet isolation, pancreatic islet is listed by: NIDDK Information Network (dkNET)
is organization facet of: Boston Area Diabetes Endocrinology Research Center
Diabetes NIDDK P30DK057521 THIS RESOURCE IS NO LONGER IN SERVICE SCR_015073 2026-02-14 02:08:24 0
Michigan Diabetes Research Center Molecular Genetics Core Facility
 
Resource Report
Resource Website
Michigan Diabetes Research Center Molecular Genetics Core Facility (RRID:SCR_015119) core facility, access service resource, service resource Core that provides services related to the application of genetic methodologies to research related to diabetes. Services include generation of targeted genetic mouse models, using CRISPR/Cas9 system in mouse or rat embryos, generation of specialty viral vectors, specialty viral reagents, and specialty mouse models. molecular genetics, research for diabetes, viral vectors, specialty viral reagents, specialty mouse models, is listed by: NIDDK Information Network (dkNET)
is organization facet of: Michigan Diabetes Research Center
Diabetes NIDDK P30DK020572 Open http://diabetesresearch.med.umich.edu/Core_MDRC_Molecular.php SCR_015119 2026-02-14 02:07:59 0
University of Washington Diabetes Research Center Administrative Core
 
Resource Report
Resource Website
University of Washington Diabetes Research Center Administrative Core (RRID:SCR_015124) core facility, access service resource, service resource, resource Core facility that supports the Diabetes Research Center in its primary mission to enhance research, education and training in diabetes, obesity and related disorders at the University of Washington and in the Greater Seattle area. The Core coordinates and manages programs, evaluates Center activities, and performs other duties. diabetes, metabolic disorder, clinical research, administrative core is listed by: NIDDK Information Network (dkNET)
has parent organization: University of Washington; Seattle; USA
has parent organization: University of Washington Diabetes Research Center
is organization facet of: University of Washington Diabetes Research Center
Diabetes NIDDK P30DK017047 Available to the research community SCR_015124 2026-02-14 02:07:59 0

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