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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
HiC-Pro
 
Resource Report
Resource Website
100+ mentions
HiC-Pro (RRID:SCR_017643) software application, data processing software, software resource, workflow software Software tool as optimized and flexible pipeline for Hi-C data processing. Used to process Hi-C data, from raw fastq files, paired end Illumina data, to normalized contact maps. Hi-C, data, raw, fastq, file, paired, Illumina, normalized, contact, map, bio.tools is listed by: Debian
is listed by: bio.tools
France Genomique National infrastructure ;
Labex Deep ;
European Research Coucil ;
ERC Advanced Investigator award ;
European Commission ;
ABS4NGS project ;
National Human Genome Research Institute ;
Paris Alliance of Cancer Research Institutes ;
Howard Hughes Medical Institute
PMID:26619908 Free, Available for download, Freely available biotools:hic-pro https://bio.tools/hic-pro SCR_017643 2026-02-17 10:03:16 206
OrthoFinder
 
Resource Report
Resource Website
1000+ mentions
OrthoFinder (RRID:SCR_017118) data analysis software, software application, data processing software, software resource Software Python application for comparative genomics analysis. Finds orthogroups and orthologs, infers rooted gene trees for all orthogroups and identifies all of gene duplcation events in those gene trees, infers rooted species tree for species being analysed and maps gene duplication events from gene trees to branches in species tree, improves orthogroup inference accuracy. Runs set of protein sequence files, one per species, in FASTA format. comparative, genomic, analysis, find, orthogroup, ortholog, infer, gene, tree, duplicate, accuracy, protein, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Bill and Melinda Gates Foundation ;
UKAID
PMID:26243257
DOI:10.1101/466201
Free, Available for download, Freely available biotools:OrthoFinder, OMICS_09733, BioTools:OrthoFinder https://bio.tools/OrthoFinder
https://bio.tools/OrthoFinder
https://bio.tools/OrthoFinder
SCR_017118 OrthoFinder2, OrthoFinder 2026-02-17 10:03:32 2899
tximport
 
Resource Report
Resource Website
50+ mentions
tximport (RRID:SCR_016752) data analysis software, software application, data processing software, software resource Software R package for importing pseudoaligned reads into R for use with downstream differential expression analysis. Used for import and summarize transcript level estimates for transcript and gene level analysis. pseudoaligned, reads, R, differential, expression, analysis, gene, transcript, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
works with: edgeR
works with: DESeq2
SNSF 143883;
European Commission ;
NCI T32 CA009337
DOI:10.12688/f1000research.7563.1 Free, Available for download, Freely available biotools:tximport https://bioconductor.org/packages/tximport/
https://bioconductor.org/packages/devel/bioc/vignettes/tximport/inst/doc/tximport.html
https://github.com/F1000Research/tximport
https://bio.tools/tximport
https://zenodo.org/record/35123#.W_w3behKiM8 SCR_016752 tximport v1.4.0 2026-02-17 10:02:45 91
Nephele
 
Resource Report
Resource Website
10+ mentions
Nephele (RRID:SCR_016595) web application, production service resource, analysis service resource, service resource, software resource, data analysis service Cloud based platform for simplified, standardized and reproducible microbiome data analysis. Allows users to process microbiome datasets through pipelines of existing software tools. microbiome, datasets, process, analyze, metagenome, sequencing, data, bio.tools uses: mothur
uses: QIIME
uses: biobakery
uses: A5-miseq
is listed by: NIAID
is listed by: bio.tools
is listed by: Debian
has parent organization: OCICB
NIH Department of Health and Human Services GS35F0373X PMID:29028892 Free, Available for download, Freely available biotools:nephele https://github.com/niaid/Nephele
https://bio.tools/nephele
SCR_016595 2026-02-17 10:03:28 27
scanpy
 
Resource Report
Resource Website
100+ mentions
scanpy (RRID:SCR_018139) data analysis software, software application, data processing software, software resource Software Python tool for large scale single cell gene expression data analysis. Integrates analysis possibilities of established R-based frameworks, provides pre processing, visualization, graph-drawing and diffusion maps, clustering, identification of marker genes for clusters via differential expression tests and pseudo temporal ordering via diffusion pseudo time. Large scale, single cell, gene expression, data analysis, R, pre processing, visualization, graph drawing, diffusion map, clustering, marker gene, differential expression test, bio.tools uses: BBKNN
is used by: triku
is used by: MUON
is listed by: Debian
is listed by: bio.tools
is related to: Anndata
has plug in: infercnvpy
Helmholtz Postdoc Programme ;
German Research Foundation
PMID:29409532 Free, Available for download, Freely available biotools:scanpy, BioTools:scanpy https://icb-scanpy.readthedocs-hosted.com/en/stable/
https://bio.tools/scanpy
https://bio.tools/scanpy
https://bio.tools/scanpy
SCR_018139 Single Cell Analysis in Python 2026-02-17 10:03:24 221
DrivAER
 
Resource Report
Resource Website
1+ mentions
DrivAER (RRID:SCR_019076) data analysis software, software application, data processing software, software resource Software tool as method for identification of driving transcriptional programs based on AutoEncoder derived Relevance scores. Infers relevance scores for transcriptional programs with respect to specified outcomes of interest in single-cell RNA sequencing data, such as psuedotemporal ordering or disease status.Used for manifold interpretation in scRNA-seq data. Manifold interpretation, scRNAseq data, relevance scores infering, transcriptional program, psuedotemporal ordering, disease status, data, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:drivaer https://bio.tools/drivaer SCR_019076 Driving transcriptional programs using AutoEncoder based Relevance scores 2026-02-17 10:03:51 1
Epigenomics Workflow on Galaxy and Jupyter
 
Resource Report
Resource Website
1+ mentions
Epigenomics Workflow on Galaxy and Jupyter (RRID:SCR_017544) narrative resource, workflow, software application, data or information resource, data processing software, training material, data analysis software, software resource Software tool as epigenomics analysis pipeline for analysis of ChIP-Seq and RNA-Seq data using Docker images containing Galaxy and Jupyter. Epigenomic, analysis, pipeline, ChIP-Seq, RNA-Seq, data, Galaxy, Jupyter, bio.tools is listed by: bio.tools
is listed by: Debian
Agencia Estatal de Investigación of Spain SEV-2016-0672 (2017-2021) Free, Available for download, Freely available biotools:Epigenomics_Workflow_on_Galaxy_and_Jupyter https://zenodo.org/record/3298029
https://bio.tools/Epigenomics_Workflow_on_Galaxy_and_Jupyter
SCR_017544 REA pipeline 2026-02-17 10:03:15 2
IMGT HighV-QUEST
 
Resource Report
Resource Website
10+ mentions
IMGT HighV-QUEST (RRID:SCR_018196) alignment software, software application, data or information resource, production service resource, data processing software, analysis service resource, service resource, software resource, portal, image analysis software Next generation B and T cell sequence alignment and characterization online surface by IMGT. Web portal for immunoglobulin (IG) or antibody and T cell receptor (TR) analysis from NGS high throughput and deep sequencing. Next generation sequencing, B cell, T cell, sequence alignment, immunoglobulin, antibody, T cell receptor, analysis, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
NHMRC ;
MESR ;
CNRS ;
Université Montpellier 2 ;
France ;
GENCI
PMID:22647994
PMID:23995877
PMID:22665256
Restricted biotools:IMGt_HighV-QUESt https://bio.tools/IMGT_HighV-QUEST SCR_018196 IMGT/HighV QUEST, IMGT/HighV-QUEST, IMGT web portal 2026-02-17 10:03:43 11
PM4NGS
 
Resource Report
Resource Website
1+ mentions
PM4NGS (RRID:SCR_019164) data management software, software application, workflow software, data processing software, data analysis software, software resource, software toolkit Software tool to generate standard organizational structure for Next Generation Sequencing data analysis. Includes directory structure for project, several Jupyter notebooks for data management and CWL workflows for pipeline execution. NGS workflow, standard organizational structure generation, Next Generation Sequencing data, NGS data analysis, NGS data analysis workflow, data integration, Jupyter notebook, CWL format, bio.tools is listed by: bio.tools
is listed by: Debian
Intramural Research Program of the National Library of Medicine NIH DOI:10.7490/f1000research.1117155.1 Free, Freely available biotools:pm4ngs https://bio.tools/pm4ngs SCR_019164 Project Manager for Next Generation Sequencing 2026-02-17 10:03:37 1
ngsRelate
 
Resource Report
Resource Website
1+ mentions
ngsRelate (RRID:SCR_016588) data analysis software, software application, data processing software, software resource Software tool for estimating pairwise relatedness from next-generation sequencing data. estimating, pairwise, relatedness, next, generation, sequencing, data, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
Danish National Research Foundation ;
Danish Council for Independent Research
PMID:26323718 Free, Available for download, Freely available biotools:ngsRelateV2, biotools:ngsrelate https://bio.tools/ngsRelateV2
https://bio.tools/ngsrelate
http://www.popgen.dk/software/index.php?title=NgsRelate&oldid=694 SCR_016588 ngsRelateV2 2026-02-17 10:03:26 6
ComplexHeatmap
 
Resource Report
Resource Website
1000+ mentions
ComplexHeatmap (RRID:SCR_017270) software application, data processing software, data analysis software, software resource, data visualization software Software package to arrange multiple heatmaps and support various annotation graphics. Used to visualize associations between different sources of data sets and to reveal potential patterns. arrange, multiple, heatmap, visualize, data, pattern, genomic, dataset, bio.tools is listed by: Debian
is listed by: bio.tools
German Cancer Research Center-Heidelberg Center for Personalized Oncology ;
BMBF
PMID:27207943 Free, Available for download, Freely available biotools:complexheatmap https://github.com/jokergoo/ComplexHeatmap
https://bio.tools/complexheatmap
SCR_017270 2026-02-17 10:03:33 3266
SWISS-MODEL
 
Resource Report
Resource Website
1000+ mentions
SWISS-MODEL (RRID:SCR_018123) data access protocol, data or information resource, service resource, software resource, web service Software tool as fully automated protein structure homology modeling server, accessible via ExPASy web server, or from program DeepView Swiss Pdb-Viewer. Structural bioinformatics web-server dedicated to homology modeling of 3D protein structures. Used to make protein modelling accessible to all biochemists and molecular biologists. 3D protein structure, homology modeling server, protein modeling, structural bioinformatics, automated comparative modeling, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: ExPASy Bioinformatics Resource Portal
is related to: Swiss-PdbViewerDeepViewv4.0
has parent organization: University of Basel; Basel; Switzerland
provides: SWISS-MODEL Repository
PMID:12824332 Free, Freely available biotools:swiss-model_workspace, biotools:swiss_model https://bio.tools/swiss_model
https://bio.tools/swiss-model_workspace
SCR_018123 2026-02-17 10:03:44 2796
SIGNOR
 
Resource Report
Resource Website
10+ mentions
SIGNOR (RRID:SCR_018485) storage service resource, data or information resource, database, service resource, data repository Software application to organize and store in structured format signaling information published in scientific literature. Information is stored as binary causative relationships between biological entities and can be represented graphically as activity flow. Each relationship is linked to literature reporting experimental evidence. Each node is annotated with chemical inhibitors that modulate its activity. Signaling information is mapped to human proteome. SIGNOR 2.0 stores manually annotated causal relationships between proteins and other biologically relevant entities including chemicals, phenotypes, complexes, etc with compliance to FAIR data principles. Signal transduction data, signaling information, published data collection, activity flow, chemical inhibitor, human proteome, manually annotated data, protein, protein relationship, FAIR data, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: REDIportal
Italian Association for Cancer Research ;
ELIXIR-IIB ;
Italian Node of the European ELIXIR infrastructure ;
EMBL-EBI
PMID:31665520 Free, Available for download, Freely available biotools:signor https://bio.tools/signor SCR_018485 SIGnaling Network Open Resource, SIGNOR 2.0 2026-02-17 10:03:05 40
SeqBuster
 
Resource Report
Resource Website
10+ mentions
SeqBuster (RRID:SCR_009616) data analysis software, software application, data processing software, software resource Software tool for processing and analysis of small RNAs datasets.Reveals ubiquitous miRNA modifications in human embryonic cells. small RNAs datasets, ubiquitous miRNA modifications, human embryonic cells, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Spanish Ministry of Health ;
CIBERESP ;
Sixth Framework Programme of the European Commission ;
Spanish Ministry of Science and Innovation
PMID:20008100 Free, Available for download, Freely available OMICS_00367, biotools:seqbuster https://bio.tools/seqbuster SCR_009616 2026-02-17 10:01:25 30
MACH
 
Resource Report
Resource Website
500+ mentions
MACH (RRID:SCR_009621) data analysis software, software application, data processing software, software resource QTL analysis based on imputed dosages/posterior_probabilities. genetic association, genomic analysis, imaging genomics, snp, gene, quantitative trait analysis, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
PMID:21058334
PMID:19715440
DOI:10.1002/gepi.20533
Free, Non-commercial, Acknowledgement requested nlx_155856, biotools:mach http://www.nitrc.org/projects/mach
https://bio.tools/mach
https://sources.debian.org/src/mach-haplotyper/ SCR_009621 mach2qtl, MaCH 2026-02-17 10:01:30 925
BEAST
 
Resource Report
Resource Website
5000+ mentions
BEAST (RRID:SCR_010228) software application, data processing software, data analysis software, sequence analysis software, software resource, software repository A cross-platform software program for Bayesian MCMC analysis of molecular sequences. It is entirely orientated towards rooted, time-measured phylogenies inferred using strict or relaxed molecular clock models. It can be used as a method of reconstructing phylogenies but is also a framework for testing evolutionary hypotheses without conditioning on a single tree topology. BEAST uses MCMC to average over tree space, so that each tree is weighted proportional to its posterior probability. We include a simple to use user-interface program for setting up standard analyses and a suit of programs for analysing the results. bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: TempEst
is related to: BEAST2
is related to: PhyDyn
has parent organization: University of Edinburgh; Scotland; United Kingdom
DOI:10.1186/1471-2148-7-214 nlx_156859, OMICS_04233, biotools:beast, SCR_015988 http://www.nitrc.org/projects/beast-library
https://bio.tools/beast
https://sources.debian.org/src/beast-mcmc/
http://beast.bio.ed.ac.uk/Main_Page SCR_010228 BEaST Segmentation Library, Beast Software 2026-02-17 10:01:47 6460
WEBLOGO
 
Resource Report
Resource Website
1000+ mentions
WEBLOGO (RRID:SCR_010236) data access protocol, service resource, web service, software resource Web application to generate sequence logos, graphical representations of patterns within multiple sequence alignment. Designed to make generation of sequence logos easy. Sequence logo generator. Generate sequence logo, pattern graphical representation, multiple sequence alignment, sequence logo generator, amino acid sequence alignment, nucleic acid sequence alignment, sequence alignment representation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of California at Berkeley; Berkeley; USA
NHGRI K22 HG00056;
Searle Scholars program ;
NIGMS P50 GM62412
PMID:15173120 Free, Available for download, Freely available nlx_156853, biotools:weblogo_3 http://weblogo.threeplusone.com/
https://bio.tools/weblogo_3
SCR_010236 WebLogo Version 2.8.2, WebLogo3, WebLogo 2026-02-17 10:01:40 3653
Pathema
 
Resource Report
Resource Website
1+ mentions
Pathema (RRID:SCR_010585) Pathema data or information resource, production service resource, analysis service resource, database, service resource, data analysis service Pathema is one of the eight Bioinformatics Resource Centers designed to serve as a core resource for the bio-defense and infectious disease research community. Pathema strives to support basic research and accelerate scientific progress for understanding, detecting, diagnosing and treating an established set of six target NIAID Category A-C pathogens: Category A priority pathogens; Bacillus anthracis and Clostridium botulinum, and Category B priority pathogens; Burkholderia mallei, Burkholderia pseudomallei, Clostridium perfringens and Entamoeba histolytica. Each target pathogen is represented in one of four distinct clade-specific Pathema web resources and underlying databases developed to target the specific data and analysis needs of each scientific community. All publicly available complete genome projects of phylogenetically related organisms are also represented, providing a comprehensive collection of organisms for comparative analyses. Pathema facilitates the scientific exploration of genomic and related data through its integration with web-based analysis tools, customized to obtain, display, and compute results relevant to ongoing pathogen research. Pathema serves the bio-defense and infectious disease research community by disseminating data resulting from pathogen genome sequencing projects and providing access to the results of inter-genomic comparisons for these organisms. The Pathema BRC contract ends in December 2009. At that time JCVI will cease maintenance of the Pathema web resource and data. The PATRIC team, located at the Virginia Bioinformatics Institute, created and maintains a consolidated BRC for all of the NIAID category A-C priority pathogenic bacteria. The EuPathDB team at the University of Pennsylvania will support all eukaryotic pathogens. Pathema transferred all data and software to PATRIC and EuPathDB for incorporation into their new Web-based bioinformatics resource. bacillus anthracis, clostridium botulinum, burkholderia mallei, burkholderia pseudomallei, clostridium perfringens, entamoeba histolytica, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: J. Craig Venter Institute
NIAID contract HHSN266200400038C PMID:19843611 biotools:pathema, nlx_45829 https://bio.tools/pathema SCR_010585 Pathema Genome Resource, Pathema Bioinformatics Resource Center 2026-02-17 10:01:31 6
icy
 
Resource Report
Resource Website
100+ mentions
icy (RRID:SCR_010587) ICY software development environment, software development tool, software application, image processing software, data processing software, source code, software resource, service resource, software repository, image analysis software An open community platform for bioimage informatics providing the software resources to visualize, annotate and quantify bioimaging data. To bridge the gap between developers and users, it combines: a) an open-source image analysis software, offering a powerful and flexible environment for developers such as applied mathematicians to write algorithms fast and efficiently; b) a common set of tools to view and manipulate data, and a set of plugins to perform specific quantification or analysis on images; c) a community-based website centralizing all plugins and resources to facilitate their management and maximize their visibility towards users. Workspaces are virtual groups of plugins dedicated to a specific application or image processing domain. By downloading a workspace, ICY automatically installs all corresponding plugins. The workspaces are enabled, but the editing section is not ready yet. If you want to publish a plugin on this website, its code has to be GPL. Source code is available and provided in each application download. image analysis, microscopy, javascript, python, plugin, protocol, script, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Pasteur Institute
Centre National de la Recherche Scientifique ;
French National Research Agency ANR-10-INBS-04-06
PMID:22743774 Free, Open unspecified license, GNU General Public License, v3, The community can contribute to this resource biotools:icy, nlx_45928 https://bio.tools/icy SCR_010587 icy bioimage analysis 2026-02-17 10:01:48 320
Geneious
 
Resource Report
Resource Website
10000+ mentions
Geneious (RRID:SCR_010519) data management software, software application, data processing software, data analysis software, sequence analysis software, software resource, software toolkit Software package for sequence alignment, assembly and analysis. Integrated and extendable desktop software platform for organization and analysis of sequence data. Bioinformatics software platform packed with molecular biology and sequence analysis tools. Sequence alignment software, data management software, analysis software, Geneious Biologics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is parent organization of: Geneious Microsatellite Plugin
PMID:22543367 Restricted OMICS_00016, biotools:geneious http://nebc.nerc.ac.uk/news/geneiousonbl
https://bio.tools/geneious
SCR_010519 Geneious Prime, Geneious 11.0, Geneious 11.1.2, Geneious 8.1, Geneious Basic 2026-02-17 10:01:54 12252

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