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http://www.scienceexchange.com/facilities/angiogenesis-endothelial-and-pro-angiogenic-cell-core-aepcc-iu

The Angiogenesis, Endothelial & Pro-Angiogenic Cell Core (AEPCC) is a state-of-the-art facility that has been established through the Indiana University Melvin and Bren Simon Cancer Center, a National Cancer Institute-designated cancer center, to conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. In addition to possessing the in vitro and in vivo assays that define the endothelial progenitor outgrowth cells that possess in vivo vessel forming ability, the AEPCC recently stringently defined a population of pro-angiogenic and anti-angiogenic circulating hematopoietic stem and progenitor cells (CHSPCs) that has been shown to regulate angiogenesis. Discovery of these novel CHSPC subsets demonstrates the uniqueness and strength of the approach by the AEPCC that requires both phenotypic and functional data to validate specific circulating cells that participate in new blood vessel formation. The specific assays offered by the AEPCC function as quantitative analytical tools, potential biomarkers of several hematopoietic diseases, and as experimental platforms for understanding the basic mechanisms of angiogenesis and the interplay between the endothelial and hematopoietic systems. For example, not only are CHSPCs critical for normal and abnormal angiogenesis, but we and others have reported that certain endothelial cells are critical for CHSPC expansion ex vivo and that endothelial cells promote CHSPC engraftment post-ablation. The AEPCC serves to directly perform all of the assays required to analyze research samples, and as a consultation, education, and new assay development site for scientists within and outside the IU School of Medicine and Indiana University. Furthermore, the AEPCC is one of only five nationally recognized Core Centers of Excellence in Molecular Hematology by the National Institutes of Health and is a certified core of the Indiana Clinical and Translational Sciences Institute (CTSI).

Proper citation: IUSM Angiogenesis Endothelial and Pro-Angiogenic Cell Core (RRID:SCR_011001) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/genomics-core-facility-lsu

The Genomics Core Facility seeks to achieve high quality research data production through education of core facility users, optimal use of qPCR and RNA/DNA quality and quantity instrumentation, and quality Sanger sequencing, next-generation sequencing, robotics, and microarray services. Services are provided to internal and external researchers.

Proper citation: LSU Genomics Core Facility (RRID:SCR_011004) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/magnetic-resonance-research-facility-mrrf-uiowa

The University of Iowa MR Research Facility was established in August of 2004 with the acquisition of a Siemens Trio 3T scanner, shared between research and clinical usage. While the Center is within the Department of Radiology, it is run as a Core University facility. The facility is managed on a daily basis by Vincent Magnotta, PhD, Alan Stolpen, MD, PhD, and Dan Thedens, PhD. Oversight is provided by a Research Advisory committee that reviews new project proposals and equipment acquisitions. Since its inception, the equipment managed by the Research Center has expanded. In 2006, a research dedicated Siemens Avanto 1.5T scanner was loaned to the University by Siemens Medical Solutions to support research studies. Then, in 2007 an NIH/NCRR High End Instrumentation grant supported the acquisition of a research dedicated Siemens TIM Trio 3T scanner. Standard operating hours for the research-dedicated 3T TIM Trio scanner are from 8:00 a.m. to 6:00 p.m., Monday through Friday. During this time, a technologist is provided to run the scanner. The shared research 3T TIM Trio scanner is available all day Tuesdays (8:00 a.m. - 4:30 p.m.), and Thursday afternoons (12:00 p.m. - 4:30 p.m.) for research studies. The shared Avanto 1.5T scanner is available Mondays, Wednesdays and Fridays from 2:00 p.m. to 4:00 p.m. The scanners are also available after-hours if technologist coverage is available, or if the user is certified to conduct MR studies on their own. The current rate for scanner usage is $600 per hour and can be scheduled in half hour increments.

Proper citation: University of Iowa Magnetic Resonance Research Facility (RRID:SCR_011014) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/rodent-behavior-core-nyu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 24,2024. Rodent Behavior Core, located in Berg, is slated to open to the NYULMC research community in September, 2012. The Rodent Behavior Core will provide facilities and equipment for: -Spatial Learning and Memory (Morris Water Maze, Place Preference) -Associative Memory Formation (Fear Conditioning) -Anxiety and Depression (Elevated Plus, Forced Swim, Tail Suspension, Sucrose Preference) -Sensory Motor Gating (Prepulse Inhibition, Acoustic Startle) -Drug Addiction and Withdrawal (Conditioned Place Preference, Locomotor Hyperactivity) -Social Learning (Three Chambered Arena) -Novelty Detection (Objection Recognition) -Motor Learning (Rotating Rod test) -Perseverative Learning (Y-Maze) -Working Memory (Radial Arm Maze) -Real time video tracking to adapt user designed paradigms

Proper citation: NYU Rodent Behavior Core (RRID:SCR_010983) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/australian-synchrotron

The Australian Synchrotron is a source of highly intense light ranging from infrared to hard x-rays used for a wide variety of research purposes. Officially opened in July 2007, the Australian Synchrotron is one of fewer than 40 similar facilities around the world. It is the largest stand-alone piece of scientific infrastructure in the southern hemisphere.

Proper citation: Australian Synchrotron (RRID:SCR_010984) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/stem-cell-research-center

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. Institutional Stem Cell Core has been discontinued, with the functions of the former Core now split into two separate operations. iPSCs: The generation and characterization of induced Pluripotent Stem Cells (iPSCs) is now being performed on a collaborative basis for both internal and external investigators. Shared Laboratory: A well-equipped shared laboratory dedicated to the culture and analysis of stem cells is available to SBP investigators.

Proper citation: Sanford-Burnham Stem Cell Core Facility (RRID:SCR_011039) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/australian-proteome-analysis-facility

APAF Ltd - Australian Proteome Analysis Facility, was the birthplace of the term proteomics in 1995 and was the world''''s first dedicated high throughput proteomics laboratory. APAF has over 15 years of experience in providing proteomic services, and combined with our leading edge infrastructure and expertise we provide total solutions for all your proteomic research needs. APAF''''s mission is to assist the scientific community address their protein analysis needs.

Proper citation: MQ Australian Proteome Analysis Facility (RRID:SCR_011040) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/mass-spectrometry-core

The Mass Spectrometry Core is dedicated to providing a wide range of mass spectral analyses. As an integral component of the BRF Proteomics Section, it is a vital proteomics resource, providing high quality data in a timely manner and engaging investigators in the interpretation of the results.

Proper citation: UTMB Mass Spectrometry Core (RRID:SCR_011041) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/university-of-illinois-at-chicago

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Portal, Core facility

Proper citation: University of Illinois at Chicago Labs and Facilities (RRID:SCR_012196) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/translational-research-laboratory

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Translational Research Laboratory at the Peter MacCallum Cancer Centre offers oncology focused, small animal PET imaging services to both academic and commercial investigators. Using the wide range of mouse models of cancer available at Peter Mac, experiments are tailored to investigators needs and performed in state of the art facilities. Infrastructure available includes 2 Philips Mosaic PET scanners, on-site radiotracer production, fully trained imaging staff and a dedicated animal facility. Digital autoradiography using the Biospace BetaImager and MicroImager allows high resolution ex-vivo imaging of labelled compounds in whole animal or tissue sections. The VisualSonics Vevo 770 small animal ultrasound is available for detection and monitoring of in vivo tumor growth. Ex-vivo correlative biomarker studies are also available.

Proper citation: Peter Mac Translational Research Laboratory (RRID:SCR_012198) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/genomics-core-facility-virginia

The GCF provides second generation genome sequencing service to all members of the scientific community. Using the 454 Life Sciences/Roche Genome Sequencer FLX, we facilitate data collection and analysis.

Proper citation: UVa Genomics Core Facility (RRID:SCR_012197) Copy   

•   Source: SciCrunch Registry

https://www.uclahealth.org/departments/pathology/research-services/technology-center-genomics-bioinformatics-tcgb

Core is a fully automated, high-throughput genomic Center equipped with next generation sequencing and microarray platforms. TCGB provides genomics technologies, comprehensive services, specialized expertise and a wide range of trainings, enabling these services to serve basic science and translational/clinical research. In addition, TCGB provides pre-experiment consultation and post-experiment support, including preparation of grant applications, publications, and strategic planning for additional research steps. TCGB also provides educational training to faculty, staff, and students to raise awareness of new directions and major discoveries in the areas of genomics and bioinformatics.

Proper citation: University of California Los Angeles Technology Center for Genomics and Bioinformatics Core Facility (RRID:SCR_012204) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/keck-biophysics-facility-northwestern

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 31,2025. The award-wining Keck Biophysics Facility at Northwestern University has a comprehensive set of state of the art instruments for biophysical and biochemical characterization of macromolecules and their interactions. We provide staff-service, technical expertise and assistance to investigators and companies in the continental US and Canada. The Facility has 15 years of experience with a broad array of biophysical techniques and has generated over 500 publications in top-tier journals.

Proper citation: Northwestern University Keck Biophysics Facility (RRID:SCR_012203) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/affina-biotechnologies-inc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Affina Biotechnologies is dedicated to excellence in helping our customers develop measurements of activities, kinetics and affinities of interactions and concentrations of biomolecules. We offer a unique mix of label-free and label-dependent assay technologies supported by scientific and technical expertise and a wide range of instrumentation.

Proper citation: Affina Biotechnologies (RRID:SCR_012207) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/ips-core

The new iPSC Core generates custom-designed iPSCs from mouse and human cells, including disease-specific human iPSCs. iPSCs from other species are currently under development. The Core is currently using both lentiviral- and sendai viral vector systems to deliver reprogramming factors to cells. Both systems are efficient, with the latter system having the advantage to generate iPSCs with a non-DNA-integrating vector system.

Proper citation: CU Denver iPSC Core (RRID:SCR_012176) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/university-of-colorado-denver

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Portal, Core facility

Proper citation: University of Colorado Denver Labs and Facilities (RRID:SCR_012175) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/transgenic-and-gene-targeting-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22,2024. Transgenic and Gene Targeting Core is a full-service facility designed to assist you in generating genetically engineered mouse models for biomedical research. Our services include gene targeting in embryonic stem cells, the generation of ES cell-derived knockout and knockin mice, transgenic mice (conventional and BAC transgenic mice) and the cryo-preservation of mouse lines. The latter service is of particular importance for investigators that have long-term projects with non-commercial mouse lines. Changes in the genetic make-up of your mouse lines that occur spontaneously over time (gene drift) and disease outbreaks can significantly affect the outcome of your research. It is therefore advisable to preserve your mouse lines, providing you with a backup of your valuable research tools. We currently offer both embryo cryopreservation as well as sperm cryopreservation for this purpose.

Proper citation: CU Denver Transgenic and Gene Targeting Core (RRID:SCR_012177) Copy   

•   Source: SciCrunch Registry

http://www.mmc.edu/research/centers/research-centers/metrc/core-facilities.html

Core facility that aids investigators and trainees with high performance computation in proteomics, as well as other omics type applications needing efficient analysis of large-scale biological data sets. The ability to incorporate proteomics into translational and clinical biomedical research is critical for the discovery of therapeutic interventions and high fidelity biomarkers of disease and response to therapy. The Core provides state-of-the-art services, training, and bioinformatics-driven data analysis to the Meharry translational research community.

Proper citation: Meharry Proteomics Core (RRID:SCR_012179) Copy   

•   Source: SciCrunch Registry

https://www.monash.edu/researchinfrastructure/micromon

Provides complete sequencing and data analysis service based around second generation Illumina Genome Analyzer (GAIIx) and Illumina MiSeq sequencing platform. They also offer Agilent Bioanalyzer RNA and DNA analysis, Covaris focussed acoustic shearing of nucleic acids and tissues, qPCR assay design, execution and analysis, oligonucleotide synthesis and capillary electrophoresis (CE/Sanger) sequencing. Offers expertise in advanced DNA and RNA technologies.

Proper citation: Monash University Micromon Core Facility (RRID:SCR_012170) Copy   

•   Source: SciCrunch Registry

https://lsom.uthscsa.edu/dcsa/research/cores-facilities/optical-imaging/

Service resource which makes imaging technology available to investigators on UTHSCSA campus and neighboring scientific community. Core Optical Imaging Facility offers access to technology for imaging of living cells, tissues, and animals, consultation, education and assistance regarding theory and application of optical imaging techniques, technical advice on specimen preparation techniques and probe selection.

Proper citation: Texas University Health Science Center at San Antonio Long School of Medicine Department of Cell Systems and Anatomy Optical Imaging Core Facility (RRID:SCR_012171) Copy   

•   Source: SciCrunch Registry