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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SPRING
 
Resource Report
Resource Website
10+ mentions
SPRING (RRID:SCR_023578) data access protocol, web service, software resource Interactive web tool to visualize single cell data using force directed graph layouts. Kinetic interface for visualizing high dimensional single cell expression data. Collection of pre-processing scripts and web browser based tool for visualizing and interacting with high dimensional data. visualizing high dimensional single cell expression data, single cell expression data visualization, high dimensional data, has parent organization: Harvard University; Cambridge; United States NIGMS 5T32GM080177;
NCI 1R33CA212697;
Burroughs-Wellcome Career Award at the Scientific Interface ;
Edward J Mallinckrodt Foundation Fellowship
PMID:29228172 Free, Available for download, Freely available https://github.com/AllonKleinLab/SPRING/
https://github.com/AllonKleinLab/SPRING_dev
SCR_023578 2026-02-17 10:04:25 24
Kinase Enrichment Analysis 3
 
Resource Report
Resource Website
10+ mentions
Kinase Enrichment Analysis 3 (RRID:SCR_023623) KEA3 data access protocol, web service, software resource Web server application that infers overrepresentation of upstream kinases whose putative substrates are in user inputted list of proteins. Used to analyze data from phosphoproteomics and proteomics studies to predict upstream kinases responsible for observed differential phosphorylations. overrepresentation of upstream kinases, upstream kinases, upstream kinases substrates, user inputted list of proteins, has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA NHLBI U54 HL127624;
NCI U24 CA224260;
NIGMS T32 GM062754;
NIH Office of the Director OT3 OD025467
PMID:34019655 Free, Freely available SCR_023623 2026-02-17 10:04:25 11
CellProfiler Image Analysis Software
 
Resource Report
Resource Website
1000+ mentions
CellProfiler Image Analysis Software (RRID:SCR_007358) image analysis software, software application, data processing software, software resource Software tool to enable biologists without training in computer vision or programming to quantitatively measure phenotypes from thousands of images automatically. It counts cells and also measures the size, shape, intensity and texture of every cell (and every labeled subcellular compartment) in every image. It was designed for high throughput screening but can perform automated image analysis for images from time-lapse movies and low-throughput experiments. CellProfiler has an increasing number of algorithms to identify and measure properties of neuronal cell types. high-throughput, high content imaging, software, image, cell, phenotype, measurement, subcellular, intensity, size, shape, analysis, algorithm is listed by: Debian
is related to: CellProfiler Analyst
has parent organization: Broad Institute
NIGMS R01 GM089652;
NIGMS RC2 GM092519;
NHGRI RL1 HG004671
PMID:21349861
PMID:17076895
PMID:19014601
PMID:19188593
Free, Available for download, Freely available SCR_010649, nlx_66812, nif-0000-00280 https://sources.debian.org/src/cellprofiler/ SCR_007358 Cell Profiler, CellProfiler - cell image analysis software 2026-02-17 10:01:14 3265
Oufti
 
Resource Report
Resource Website
10+ mentions
Oufti (RRID:SCR_016244) image analysis software, software application, data processing software, software resource Software designed for analysis of microscopy data. It performs sub-pixel precision detection, quantification of cells and fluorescence signals, as well as other image analysis functions. microscopy, data, imaging, image, analysis, pixel, fluorescent, bio.tools is listed by: Debian
is listed by: bio.tools
NIGMS R01 GM065835 PMID:26538279 biotools:oufti https://bio.tools/oufti SCR_016244 outfi 2026-02-17 10:03:22 13
Phenix.refine
 
Resource Report
Resource Website
10+ mentions
Phenix.refine (RRID:SCR_016736) Phenix.refine software application, data processing software, software resource Software tool for a general purpose crystallographic structure refinement within the PHENIX package. Serves as a critical component in automated model building, final structure refinement, structure validation and deposition to the wwPDB. crystallographic, structure, refinement, Phenix, model, building, validation is listed by: SoftCite
is provided by: Phenix
NIGMS GM063210;
US Department of Energy
PMID:22505256 Free, Available for download for non profit, For profit access PHENIX through a Consortium agreement, Tutorial available, Acknowledgement requested SCR_016736 Python-based Hierarchical ENvironment for Integrated Xtallography.refine, Phenix.refine, Phenix 2026-02-17 10:02:45 39
RSRef
 
Resource Report
Resource Website
1+ mentions
RSRef (RRID:SCR_017211) software application, data processing software, software resource Software for fitting of atomic models into density maps derived from x-ray crystallography or electron microscopy. Fitting, atomic, model, density, map, x ray, crystallography, electron, microscopy NIGMS R01 GM66875;
NIGMS R01 GM78538
PMID:23376441 Free, Available for download, Freely available http://xtal.ohsu.edu/software/rsref/readme.txt SCR_017211 2026-02-17 10:03:33 1
mosdepth
 
Resource Report
Resource Website
10+ mentions
mosdepth (RRID:SCR_018929) software application, data processing software, software resource Software command line tool for rapidly calculating genome wide sequencing coverage. Measures depth from BAM or CRAM files at either each nucleotide position in genome or for sets of genomic regions. Used for fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing quick coverage calculation for genomes and exomes. Calculating genome, wide sequencing coverage, depth measurement, BAM file, CRAM file, nucleotide position, genome, genomic region set, WGS exom, targeted sequencing, coverage calculation, exom, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01 HG006693;
NHGRI R01 HG009141;
NIGMS R01 GM124355;
NCI U24 CA209999
PMID:29096012 Free, Available for download, Freely available OMICS_20873, biotools:mosdepth https://bio.tools/mosdepth
https://sources.debian.org/src/mosdepth/
SCR_018929 2026-02-17 10:03:52 38
CWL-Airflow
 
Resource Report
Resource Website
1+ mentions
CWL-Airflow (RRID:SCR_017196) CWL DAG software application, data processing software, software resource, workflow software Software Python package to extend Airflow functionality with Common Workflow Language support. Lightweight pipeline manager supporting Common Workflow Language. Can be used to run workflows on standalone MacOS/Linux servers, on clusters, or on cloud platforms. airflow, common workflow language, cwl, pipeline, workflow, docker is listed by: OMICtools NCATS UL1 TR001425;
NIGMS DP2 GM119134
DOI:10.1101/249243
DOI:10.1093/gigascience/giz084
Free, Available for download, Freely available OMICS_26560 SCR_017196 CWL-Airflow v 1.0.16, Common Workflow Language-Airflow 2026-02-17 10:03:33 2
Bridger
 
Resource Report
Resource Website
1+ mentions
Bridger (RRID:SCR_017039) data analysis software, software application, data processing software, software resource Software package as de novo trascriptome assembler for RNA-Seq data. Framework for de novo transcriptome assembly using RNA-seq data. Can assemble all transcripts from short reads without using reference. Input RNA-Seq reads in fasta or fastq format, and ouput all assembled candidate transcripts in fasta format. Operating system Unix/Linux. de novo, transcripto, assembler, RNAseq, data, short, read, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
NSFC 61432010;
NSFC 61272016;
NCRR P20 RR016460;
NIGMS P20 GM103429
PMID:25723335 Free, Available for download, Freely available biotools:bridger, OMICS_07535 https://bio.tools/bridger SCR_017039 2026-02-17 10:02:47 6
PathwayNet
 
Resource Report
Resource Website
1+ mentions
PathwayNet (RRID:SCR_017353) data access protocol, production service resource, analysis service resource, service resource, software resource, web service, data analysis service Web user interface for interaction predictions of human gene networks and integrative analysis of user data types that takes advantage of data from diverse tissue and cell-lineage origins. Predicts presence of functional association and interaction type among human genes or its protein products on whole genome scale. Used to analyze experimetnal gene in context of interaction networks. Interface, interaction, predict, human, gene, network, integrative, analysis, user, data, tissue, cell, functional, protein, genome is listed by: OMICtools
has parent organization: Princeton University; New Jersey; USA
NIGMS R01 GM071966;
NHGRI HG005998;
NIGMS P50 GM071508
PMID:25431329 Free, Freely available SCR_017353 2026-02-17 10:02:51 7
FoXS
 
Resource Report
Resource Website
10+ mentions
FoXS (RRID:SCR_017269) data access protocol, production service resource, analysis service resource, service resource, software resource, web service Web server for computing theoretical scattering profile of structure and fitting of experimental profile. Computes SAXS profile of given atomistic model and fits it to experimental profile. Used for structural modeling applications with small angle X-ray scattering data. computing, theoretical, scattering, profile, structure, fitting, small, angle, X ray, data has parent organization: University of California at San Francisco; California; USA Weizmann Institute Advancing Women in Science ;
NIGMS R01 GM083960;
NCRR U54 RR022220;
NIGMS R01 GM105404;
Rinat (Pfizer) Inc. ;
Lawrence Berkeley National Lab IDAT program ;
NIGMS P41 GM109824
PMID:23972848
PMID:27151198
Free, Available for download, Freely available SCR_017269 Fast X-Ray Scattering 2026-02-17 10:03:11 20
BEAST2
 
Resource Report
Resource Website
100+ mentions
BEAST2 (RRID:SCR_017307) software application, data processing software, data analysis software, sequence analysis software, software resource, software toolkit Software package for advanced Bayesian evolutionary analysis by sampling trees. Used for phylogenetics, population genetics and phylodynamics. Program for Bayesian phylogenetic analysis of molecular sequences. Estimates rooted, time measured phylogenies using strict or relaxed molecular clock models. Framework can be extended by third parties. Comprised of standalone programs including BEAUti, BEAST, MASTER, RBS, SNAPP, MultiTypeTree, BDSKY, LogAnalyser, LogCombiner, TreeAnnotator, DensiTree and package manager. Bayesian, evolutionary, sampling, tree, phylogenic, analysis, Markov, chain, monte carlo, phylogenetic, population, genetic, phylodynamic, sequence is related to: BASTA
is related to: BEAST
is related to: PhyDyn
has parent organization: University of Auckland; Auckland; New Zealand
Royal Society of New Zealand Marsden award ;
European Research Council ;
NIGMS U01 GM110749;
Swiss National Science foundation ;
Max Planck Society ;
EMBL
PMID:30958812 Free, Available for download, Freely available SCR_017307 , Beast 2.5 2026-02-17 10:03:12 194
Geneshot
 
Resource Report
Resource Website
1+ mentions
Geneshot (RRID:SCR_017582) data access protocol, web service, software resource Software tool as search engine for ranking genes from arbitrary text queries. Enables to enter arbitrary search terms, to receive ranked lists of genes relevant to search terms. Returned ranked gene lists contain genes that were previously published in association with search terms, as well as genes predicted to be associated with terms based on data integration from multiple sources. Search results are presented with interactive visualizations. Ranking, gene, arbitrary, text, query, list, predict, association, data, integration, interactive, visualization, bio.tools is listed by: Debian
is listed by: bio.tools
NHLBI U54 HL127624;
NCI U24 CA224260;
NIGMS T32 GM062754;
NIH Office of the Director OT3OD025467
PMID:31114885 Free, Freely available biotools:Geneshot https://bio.tools/Geneshot SCR_017582 2026-02-17 10:03:15 4
microMS
 
Resource Report
Resource Website
1+ mentions
microMS (RRID:SCR_017443) software application, image processing software, data processing software, software resource, image analysis software Software Python platform for image guided Mass Spectrometry profiling. Provides graphical user interface for automatic cell finding and point based registration from whole slide images. Simplifies single cell analysis with feature rich image processing. Image, guided, mass, spectrometry, automatic, cell, finding, point, based, registration, whole, slide, image, analysis, processing, BRAIN Initiative is recommended by: BRAIN Initiative
has parent organization: University of Illinois at Urbana-Champaign; Illinois; USA
NIDA DA018310;
NIMH U01 MH109062;
National Science Foundation Graduate Research Fellowship Program ;
Springborn Fellowship ;
NIGMS T32 GM070421
PMID:28593377 Free, Available for download, Freely available SCR_017443 microscopy guided Mass Spectrometry 2026-02-17 10:02:52 1
Recombination Detection Program
 
Resource Report
Resource Website
100+ mentions
Recombination Detection Program (RRID:SCR_018537) RDP data analysis software, software application, data processing software, software resource Software package to analyse nucleotide sequence data and identify evidence of genetic recombination. RDP3 is version of RDP program for characterizing recombination events in DNA-sequence alignments. RDP4 is version of RDP program for detection and analysis of recombination patterns in virus genomes. DNA sequence, alignment, phylogenetic tree, nucleotide analysis, sequence data analysis, genetic recombination identification, DNA sequence alignment, recombinant pattern analysis, virus genome Wellcome Trust ;
Fund for Scientific Research Flanders ;
South African Centre of High Performance Computing ;
European Research Council ;
Spanish Ministry of Science and Education ;
South African National Research Foundation ;
University of Cape Town ;
Polyomielitis Research Foundation ;
Carnergie Corporation ;
NIAID AI090970;
NIGMS U01 GM110749;
NIAID AI100665
PMID:27774277
PMID:20798170
Free, Available for download, Freely available SCR_018537 Recombination Detection Program, RDP4, RDP3 2026-02-17 10:03:06 483
Evolutionary Couplings Server
 
Resource Report
Resource Website
10+ mentions
Evolutionary Couplings Server (RRID:SCR_018745) data access protocol, production service resource, analysis service resource, service resource, software resource, web service Web server provides functional and structural information about proteins from their evolutionary record using methods from statistical physics. Computes evolutionary couplings from sequence alignments and predicts 3D structure for your protein of interest. Allows to run former EVcouplings, EVmutation, EVfold and EVcomplex jobs. Coevolutionary sequence analysis, evolutionary coupling, protein sequence, RNA sequence alignment, predict protein structure, evolutionary sequence covariantion, 3D protein structure prediction, , bio.tools is listed by: bio.tools
is listed by: Debian
NSF GRFP DGE1144152;
DOE CSGF fellowship ;
NIGMS R01 GM106303
PMID:30304492 Free, Freely available biotools:EVcouplings https://github.com/debbiemarkslab/evcouplings
https://bio.tools/EVcouplings
SCR_018745 EVcouplings 2026-02-17 10:03:08 24
BcForms
 
Resource Report
Resource Website
BcForms (RRID:SCR_018654) data access protocol, web service, software toolkit, software resource Software toolkit for concretely describing non-canonical polymers and complexes to facilitate global biochemical networks. Web tool for describing molecular structure of macromolecular complexes, including non canonical monomeric forms, circular topologies, and crosslinks. Describes semantic meaning of whole cell computational models. Molecular structure description, molecular complex, atom, bond, protein, complex, modification, crosslinked residue, semantic meaning description, bio.tools is used by: BpForms
is used by: ObjTables
is listed by: Debian
is listed by: bio.tools
is related to: BpForms
NIBIB P41 EB023912;
NIGMS R35 GM119771;
NSF 1649014
PMID:32423472 Free, Freely available biotools:bcforms https://bio.tools/bcforms SCR_018654 2026-02-17 10:03:07 0
Datanator
 
Resource Report
Resource Website
1+ mentions
Datanator (RRID:SCR_018651) data access protocol, application programming interface, web application, data or information resource, database, software resource Software toolkit for discovering data needed to build, calibrate, and validate mechanistic models of cells. Integrated database of molecular data for quantitatively modeling cellular behavior. Web application for identifying relevant data for modeling specific organism in specific environmental condition. Data discovering, cell model, model cellular biochemistry, modeling specific organism, specific environmental condition, genomics, proteomics, epigenomics, metabolomics, system biology, bio.tools uses: BpForms
is listed by: Debian
is listed by: bio.tools
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
NIBIB P41 EB023912;
NIGMS R35 GM119771
DOI:10.1101/2020.08.06.240051 Free, Freely available biotools:datanator, r3d100013339 https://github.com/karrlab/datanator
https://bio.tools/datanator
https://doi.org/10.17616/R31NJMSB
SCR_018651 2026-02-17 10:03:47 1
Montana State University Mass Spectrometry Core Facility
 
Resource Report
Resource Website
1+ mentions
Montana State University Mass Spectrometry Core Facility (RRID:SCR_012482) service resource, access service resource, core facility Provides access to mass spectrometers and mass spectrometry expertise. The facility currently maintains the following equipment Waters Synapt-XS Q-IMS-TOF with Waters I-Class UHPLC; Agilent 6538 Q-TOF with Agilent 1290 UHPLC;Agilent 7800 Inductively Coupled Plasma with Laser Ablation (193 nm);Bruker micrOTOF with Agilent 1290 UHPLC; Agilent 6490 Triple Quadrupole Mass Spectrometer; Bruker MALDI Autoflex; Agilent GC-MS; Waters Synapt G2S-i Q-TOF with Ion Mobility. mass spectrometers, mass spectrometry expertise, proteomics, metabolomics, USEDit, ABRF is listed by: ScienceExchange
is listed by: ABRF CoreMarketplace
is related to: Montana State University Labs and Facilities
is related to: USEDit
has parent organization: Montana State University
MJ Murdock Charitable Trust ;
NIGMS P20GM103474;
Montana State University
Restricted SciEx_239, ABRF_253 https://coremarketplace.org/?FacilityID=253&citation=1 http://www.scienceexchange.com/facilities/mass-spectrometry-facility SCR_012482 Montana State University Mass Spectrometry Facility, MSU Mass Spectrometry Facility, Proteomics, Metabolomics and Mass Spectrometry Facility 2026-02-17 10:02:17 7
PEPATAC
 
Resource Report
Resource Website
1+ mentions
PEPATAC (RRID:SCR_024758) software resource, software toolkit Software standardized pipeline for ATAC-seq data analysis with serial alignments. Leverages unique features of ATAC-seq data to optimize for speed and accuracy, and provides several unique analytical approaches. Downstream analysis is simplified by standard definition format, modularity of components, and metadata APIs in R and Python. Restartable, fault-tolerant, and can be run on local hardware, using any cluster resource manager, or in provided Linux containers. We also emphasize the advantage of aligning to the mitochondrial genome serially, which improves alignment and quality control metrics. Includes quality control plots, summary statistics, and variety of data formats. ATAC-seq analysis pipeline, ATAC-seq data, analysis, serial alignments, NHGRI RM1 HG007735;
NIGMS R35 GM128636;
Howard Hughes Medical Institute ;
American Society of Hematology
PMID:34859208 Free, Available for download, Freely available https://github.com/databio/PEPATAC/releases SCR_024758 2026-02-17 10:04:52 2

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