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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ASPEX
 
Resource Report
Resource Website
1+ mentions
ASPEX (RRID:SCR_008414) ASPEX software application, software resource A set of programs for performing multipoint exclusion mapping of affected sibling pair data for discrete traits. (entry from Genetic Analysis Software) gene, genetic, genomic, c, tcl, perl, (the graphic script requires xmgr, available from ftp://ftp.teleport.com/pub/users/pturner/acegr), unix, (solaris/sunos/irix/osf-1), linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154234, biotools:aspex https://bio.tools/aspex SCR_008414 Affected Sib Pairs EXclusion map 2026-02-15 09:19:49 9
ALBERT
 
Resource Report
Resource Website
10+ mentions
ALBERT (RRID:SCR_009037) ALBERT software application, software resource Software application that estimates genotype relative risks, genotyping error rates and population risk allele frequencies from marker genotype data in case-parent trios. ALBERT uses the distribution of trio marker genotypes to compute maximum likelihood estimates for the parameters. (entry from Genetic Analysis Software) gene, genetic, genomic, c, unix, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
biotools:albert, nlx_154002 https://bio.tools/albert SCR_009037 A Likelihood Based Estimation of Risk in Trios 2026-02-15 09:20:01 47
FastTree
 
Resource Report
Resource Website
5000+ mentions
FastTree (RRID:SCR_015501) source code, software resource Source code that infers approximately-maximum-likelihood phylogenetic trees from alignments of nucleotide or protein sequences. It uses the Jukes-Cantor or generalized time-reversible (GTR) models of nucleotide evolution and the JTT, WAG, or LG models of amino acid evolution. phylogenetic tree, phylogenetic tree creation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: VeryFastTree
PMID:19377059
DOI:10.1371/journal.pone.0009490
biotools:fasttree, OMICS_14703 https://bio.tools/fasttree
https://sources.debian.org/src/fasttree/
SCR_015501 2026-02-15 09:20:54 5774
lme4
 
Resource Report
Resource Website
100+ mentions
lme4 (RRID:SCR_015654) source code, software resource Software R package. Fit linear and generalized linear mixed-effects models. The models and their components are represented using S4 classes and methods. The core computational algorithms are implemented using the 'Eigen' C++ library for numerical linear algebra and 'RcppEigen' "glue." linear mixed-effects model, s4 class, eigen c++ library, r package, r, bio.tools is listed by: CRAN
is listed by: bio.tools
is listed by: Debian
works with: R package: lmerTest
Free, Available for download biotools:lme4 https://cran.r-project.org/package=lme4
https://github.com/lme4/lme4/
https://bio.tools/lme4
SCR_015654 lme4, lme4.0, lme4: Linear Mixed-Effects Models using 'Eigen' and S4, lme4: Linear Mixed-Effects Models, R package: lme4 2026-02-15 09:21:35 327
TomoMiner
 
Resource Report
Resource Website
1+ mentions
TomoMiner (RRID:SCR_015045) source code, software resource Software platform for large-scale cryo electron subtomogram classification, alignment, and averaging. analysis platform, cryo electron subtomogram, subtomogram classification, subtomogram alignment, subtomogram averaging, subtomogram analysis, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Southern California; Los Angeles; USA
requires: Python Programming Language
requires: NumPy
requires: SciPy
requires: LAPACK linear algebra library
requires: Cython C-Extensions for Python
Available for download biotools:tomominer https://bio.tools/tomominer SCR_015045 2026-02-15 09:21:05 3
PEPPER
 
Resource Report
Resource Website
1+ mentions
PEPPER (RRID:SCR_000431) PEPPER software application, software resource A Cytoscape app designed to identify protein pathways / complexes as densely connected subnetworks from seed lists of proteins derived from pull-down assays (i.e AP-MS...). plugin, protein-protein interaction, network, bio.tools is listed by: OMICtools
is listed by: Cytoscape
is listed by: bio.tools
is listed by: Debian
PMID:25138169 Free, Available for download, Freely available biotools:pepper, OMICS_05485 https://bio.tools/pepper SCR_000431 Protein complex Expansion using Protein-Protein intERaction networks, Protein complex Expansion using Protein-Protein intERactions 2026-02-15 09:17:55 1
GERMLINE
 
Resource Report
Resource Website
100+ mentions
GERMLINE (RRID:SCR_001720) GERMLINE software application, software resource Software application for discovering long shared segments of Identity by Descent (IBD) between pairs of individuals in a large population. It takes as input genotype or haplotype marker data for individuals (as well as an optional known pedigree) and generates a list of all pairwise segmental sharing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, c++, linux, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: Columbia University; New York; USA
PMID:18971310 Free, Available for download, Freely available biotools:germline, OMICS_00202, nlx_154080 https://bio.tools/germline http://www1.cs.columbia.edu/~gusev/germline/ SCR_001720 2026-02-15 09:18:09 451
BREAKDANCER
 
Resource Report
Resource Website
100+ mentions
BREAKDANCER (RRID:SCR_001799) BreakDancer software application, software resource A Perl/C++ software package that provides genome-wide detection of structural variants from next generation paired-end sequencing reads. BreakDancerMax predicts five types of structural variants: insertions, deletions, inversions, inter- and intra-chromosomal translocations from next-generation short paired-end sequencing reads using read pairs that are mapped with unexpected separation distances or orientation. (entry from Genetic Analysis Software) gene, genetic, genomic, perl, c++, next generation sequencing, structural variant, insertion, deletion, inversion, inter-chromosomal translocation, intra-chromosomal translocation, chromosomal translocation, indel, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA
PMID:19668202 Free, Available for download, Freely available biotools:breakdancer, nlx_154253, OMICS_00307 https://bio.tools/breakdancer SCR_001799 2026-02-15 09:18:10 370
HAPLOPAINTER
 
Resource Report
Resource Website
10+ mentions
HAPLOPAINTER (RRID:SCR_001710) HaploPainter software application, software resource A pedigree drawing program, suitable in processing haplotype outputs from GENEHUNTER, ALLEGRO, MERLIN, and SIMWALK (entry from Genetic Analysis Software) gene, genetic, genomic, perl, pedigree, haplotype, draw, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:15377505 Free, Freely Available nlx_154062, OMICS_00209, biotools:haplopainter https://bio.tools/haplopainter http://haplopainter.sourceforge.net/html/ManualIndex.htm SCR_001710 2026-02-15 09:18:09 45
PEDHUNTER
 
Resource Report
Resource Website
1+ mentions
PEDHUNTER (RRID:SCR_002031) PedHunter software application, software resource Software package that facilitates creation and verification of pedigrees within large genealogies. The pedigrees are produced as files in LINKAGE format ready for linkage analysis and for drawing with a variety of drawing programs, such as PEDDRAW and cranefoot. gene, genetic, genomic, genealogy, pedigree, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: NCBI
PMID:20433770
PMID:9521925
THIS RESOURCE IS NO LONGER IN SERVICE biotools:pedhunter, OMICS_00211, nlx_154518 https://bio.tools/pedhunter SCR_002031 2026-02-15 09:18:13 2
Sequence Search and Alignment by Hashing Algorithm
 
Resource Report
Resource Website
1+ mentions
Sequence Search and Alignment by Hashing Algorithm (RRID:SCR_000544) SSAHA2 source code, software resource A program designed for the efficient mapping of sequence reads onto genomic references. The software is capable of reading most sequencing platforms and giving a range of outputs are supported. sequence, genomic, analysis, search, alignment, algorithm, mapping, bio.tools is listed by: OMICtools
is listed by: bio.tools
is related to: SMALT
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:11591649 THIS RESOURCE IS NO LONGER IN SERVICE biotools:ssaha2, OMICS_00690, nlx_93831 https://bio.tools/ssaha2 SCR_000544 ssaha2, ssaha, Sequence Search and Alignment by Hashing Algorithm 2026-02-15 09:17:56 6
ALCHEMY
 
Resource Report
Resource Website
1+ mentions
ALCHEMY (RRID:SCR_005761) ALCHEMY source code, software resource ALCHEMY is a genotype calling algorithm for Affymetrix and Illumina products which is not based on clustering methods. Features include explicit handling of reduced heterozygosity due to inbreeding and accurate results with small sample sizes. ALCHEMY is a method for automated calling of diploid genotypes from raw intensity data produced by various high-throughput multiplexed SNP genotyping methods. It has been developed for and tested on Affymetrix GeneChip Arrays, Illumina GoldenGate, and Illumina Infinium based assays. Primary motivations for ALCHEMY''s development was the lack of available genotype calling methods which can perform well in the absence of heterozygous samples (due to panels of inbred lines being genotyped) or provide accurate calls with small sample batches. ALCHEMY differs from other genotype calling methods in that genotype inference is based on a parametric Bayesian model of the raw intensity data rather than a generalized clustering approach and the model incorporates population genetic principles such as Hardy-Weinberg equilibrium adjusted for inbreeding levels. ALCHEMY can simultaneously estimate individual sample inbreeding coefficients from the data and use them to improve statistical inference of diploid genotypes at individual SNPs. The main documentation for ALCHEMY is maintained on the sourceforge-hosted MediaWiki system. Features * Population genetic model based SNP genotype calling * Simultaneous estimation of per-sample inbreeding coefficients, allele frequencies, and genotypes * Bayesian model provides posterior probabilities of genotype correctness as quality measures * Growing number of scripts and supporting programs for validation of genotypes against control data and output reformating needs * Multithreaded program for parallel execution on multi-CPU/core systems * Non-clustering based methods can handle small sample sets for empirical optimization of sample preparation techniques and accurate calling of SNPs missing genotype classes ALCHEMY is written in C and developed on the GNU/Linux platform. It should compile on any current GNU/Linux distribution with the development packages for the GNU Scientific Library (gsl) and other development packages for standard system libraries. It may also compile and run on Mac OS X if gsl is installed. diploid, genotype, snp, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Cornell University; New York; USA
NSF 0606461 PMID:20926420 GNU General Public License biotools:alchemy, nlx_149227 https://bio.tools/alchemy SCR_005761 ALCHEMY - An automated population genetic model driven SNP genotype calling method 2026-02-15 09:19:11 5
BamView
 
Resource Report
Resource Website
10+ mentions
BamView (RRID:SCR_004207) BamView source code, software resource A free interactive display of read alignments in BAM data files that can be launched with Java Web Start or downloaded. This interactive Java application for visualizing the large amounts of data stored for sequence reads which are aligned against a reference genome sequence can be used in a number of contexts including SNP calling and structural annotation. It has been integrated into Artemis so that the reads can be viewed in the context of the nucleotide sequence and genomic features. The source code is available as part of the Artemis code which can be downloaded from GitHub. bam, next-generation sequencing, java, snp calling, structural annotation, macosx, unix, windows, visualize, analyze, sequence read, reference sequence, single nucleotide polymorphism, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:22253280
PMID:20071372
GNU General Public License biotools:bamview, OMICS_00878, nlx_22933 https://bio.tools/bamview SCR_004207 2026-02-15 09:18:42 21
Genomedata
 
Resource Report
Resource Website
Genomedata (RRID:SCR_004544) Genomedata source code, software resource A format for efficient storage of multiple tracks of numeric data anchored to a genome. The format allows fast random access to hundreds of gigabytes of data, while retaining a small disk space footprint. They have also developed utilities to load data into this format. Retrieving data from this format is more than 2900 times faster than a naive approach using wiggle files. A reference implementation in Python and C components is available here under the GNU General Public License. The software has only been tested on Linux and Mac systems. genome, data, format, linux, mac, functional genomics, function, bio.tools is listed by: OMICtools
is listed by: 3DVC
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Washington; Seattle; USA
PMID:20435580 GNU General Public License nlx_53677, biotools:genomedata, OMICS_02148 https://bio.tools/genomedata SCR_004544 2026-02-15 09:18:45 0
RNAplex
 
Resource Report
Resource Website
10+ mentions
RNAplex (RRID:SCR_002763) RNAplex source code, software resource Software tool to rapidly search for short interactions between two long RNAs. interaction, rna, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Leipzig; Saxony; Germany
PMID:21593134
PMID:18434344
Free, Freely available, Available for download rid_000107, biotools:rnaplex https://bio.tools/rnaplex SCR_002763 2026-02-15 09:18:22 37
DISENTANGLER
 
Resource Report
Resource Website
1+ mentions
DISENTANGLER (RRID:SCR_009161) DISENTANGLER software application, software resource Software application that is a visualization technique for linkage disequilibrium mapping and haplotype analysis of multiple multi-allelic genetic markers. (entry from Genetic Analysis Software) gene, genetic, genomic, java/jre1.5, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154284, bIotools:disentangler https://bio.tools/disentangler SCR_009161 2026-02-15 09:19:39 4
ALOHOMORA
 
Resource Report
Resource Website
1+ mentions
ALOHOMORA (RRID:SCR_009117) ALOHOMORA software application, software resource Software application designed to facilitate genome-wide linkage studies performed with high-density single nucleotide polymorphism (SNP) marker panels such as the Affymetrix GeneChip(R) Human Mapping 10K Array. (entry from Genetic Analysis Software) gene, genetic, genomic, perl, ms-window, linux, unix, solaris, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154219, biotools:alohomora https://bio.tools/alohomora SCR_009117 2026-02-15 09:20:04 8
CASPAR
 
Resource Report
Resource Website
50+ mentions
CASPAR (RRID:SCR_009074) CASPAR software application, software resource Software application who''s main novel feature is conditional linkage analyses, in which the population can be subdivided according to criteria at some loci and analyzed for linkage at other loci. CASPAR uses simulation to overcome the problems inherent in such multiple testing. (entry from Genetic Analysis Software) gene, genetic, genomic, c, unix, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
biotools:caspar, nlx_154071 https://bio.tools/caspar SCR_009074 Computerized Affected Sibling Pair Analyzer and Reporter 2026-02-15 09:20:03 52
genehunter-imprinting
 
Resource Report
Resource Website
1+ mentions
genehunter-imprinting (RRID:SCR_009104) GENEHUNTER-TWOLOCUS software application, software resource Resource no longer in service. Documented on February 23,2021.Software tool as modification of GENEHUNTER software package . Allows for parametric multi-marker linkage analysis of dichotomous traits caused by imprinted genes. By specification of two heterozygote penetrance parameters, paternal and maternal origin of the disease allele can be treated differently in terms of probability of expression of the trait. gene, genetic, genomic, c, unix, sunos, solaris, osf, hpux, aix, ultrix, linux, ms-windows, bio.tools is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
DOI:10.1086/302911 Resource no longer in service. Documented on February 23,2021 nlx_154199, biotools:genehunter-imprinting https://bio.tools/genehunter-imprinting http://www.staff.uni-marburg.de/~strauchk/software.html SCR_009104 GENEHUNTER-MODSCORE, GENEHUNTER-PLUS, GENEHUNTER, GENEHUNTER-IMPRINTING 2026-02-15 09:19:57 1
ASSOCIATIONVIEWER
 
Resource Report
Resource Website
ASSOCIATIONVIEWER (RRID:SCR_009063) ASSOCIATIONVIEWER software application, software resource A Java application used to display SNPs in a genetic context. Supplementary data (such as genes or LD plots) is downloaded from various public data sources on the fly and saved locally in a cache. Custom data can be added as supplementary tracks. (entry from Genetic Analysis Software) gene, genetic, genomic, java, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154050, biotools:association_viewer https://bio.tools/association_viewer SCR_009063 2026-02-15 09:19:56 0

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