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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
affy
 
Resource Report
Resource Website
1000+ mentions
affy (RRID:SCR_012835) Affy software application, data processing software, data analysis software, software resource Software R package of functions and classes for the analysis of oligonucleotide arrays manufactured by Affymetrix. Used to process probe level data and for exploratory oligonucleotide array analysis. analysis, oligonucleotide, array, Affymetrix, process, probe, data, function, bio.tools is listed by: OMICtools
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: affydata
is related to: R Project for Statistical Computing
is related to: OMICtools
Danish Biotechnology Instrument Center PMID:14960456 Free, Available for download, Freely available BioTools:affy, OMICS_00740, biotools:affy https://bio.tools/affy
https://sources.debian.org/src/r-bioc-affy/
SCR_012835 Affymetrix, analysis of Affymetrix GeneChip data at the probe level, analysis of Affymetrix GeneChip data 2026-02-15 09:20:39 2996
edgeR
 
Resource Report
Resource Website
10000+ mentions
edgeR (RRID:SCR_012802) edgeR software application, data processing software, data analysis software, software resource Bioconductor software package for Empirical analysis of Digital Gene Expression data in R. Used for differential expression analysis of RNA-seq and digital gene expression data with biological replication. empirical, analysis, digital, gene, expression, data, R, RNA-seq data, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SARTools
is related to: Bioconductor
works with: tximport
NHMRC 406657;
Independent Research Institutes Infrastructure Support Scheme 361646;
Victorian State Government OIS grant ;
Melbourne International Research Scholarship ;
Harris and IBS Honours scholarships
PMID:19910308
DOI:10.1093/bioinformatics/btp616
Free, Available for download, Freely available OMICS_01308, biotools:edger https://bio.tools/edger
https://sources.debian.org/src/r-bioc-edger/
SCR_012802 edgeR, empirical analysis of digital gene expression data in R, Empirical analysis of Digital Gene Expression data in R 2026-02-15 09:20:39 21899
ENIGMA
 
Resource Report
Resource Website
100+ mentions
ENIGMA (RRID:SCR_013400) software application, data processing software, data analysis software, software resource A software tool to extract gene expression modules from perturbational microarray data, based on the use of combinatorial statistics and graph-based clustering. The modules are further characterized by incorporating other data types, e.g. GO annotation, protein interactions and transcription factor binding information, and by suggesting regulators that might have an effect on the expression of (some of) the genes in the module. Version : ENIGMA 1.1 used GO annotation version : Aug 29th 2007 genome, gene, genetic software, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Ghent University; Ghent; Belgium
is parent organization of: ENIGMA-DTI Pipeline
PMID:18402676 biotools:enigma, nlx_144365 https://bio.tools/enigma SCR_013400 2026-02-15 09:20:27 130
ImaGene
 
Resource Report
Resource Website
100+ mentions
ImaGene (RRID:SCR_002178) software application, data processing software, data analysis software, software resource Software tool as convolutional neural network to quantify natural selection from genomic data.Supervised machine learning algorithm to predict natural selection and estimate selection coefficients from population genomic data. Can be used to estimate any parameter of interest from evolutionary population genetics model., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. microarray analysis, machine vision, convolutional neural network, quantify natural selection, genomic data, population genomic data, evolutionary population, genetics model, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Imperial College London ;
Politecnico di Milano
PMID:31757205 THIS RESOURCE IS NO LONGER IN SERVICE biotools:ImaGene, OMICS_00841 https://github.com/mfumagalli/ImaGene
https://bio.tools/ImaGene
http://www.biodiscovery.com/software/imagene/ SCR_002178 2026-02-15 09:18:15 405
Bioinformatic Harvester IV (beta) at Karlsruhe Institute of Technology
 
Resource Report
Resource Website
1000+ mentions
Bioinformatic Harvester IV (beta) at Karlsruhe Institute of Technology (RRID:SCR_008017) software application, data processing software, database, software resource, data acquisition software, data or information resource Harvester is a Web-based tool that bulk-collects bioinformatic data on human proteins from various databases and prediction servers. It is a meta search engine for gene and protein information. It searches 16 major databases and prediction servers and combines the results on pregenerated HTML pages. In this way Harvester can provide comprehensive gene-protein information from different servers in a convenient and fast manner. As full text meta search engine, similar to Google trade mark, Harvester allows screening of the whole genome proteome for current protein functions and predictions in a few seconds. With Harvester it is now possible to compare and check the quality of different database entries and prediction algorithms on a single page. Sponsors: This work has been supported by the BMBF with grants 01GR0101 and 01KW0013. function, gene, bioinformatics, data, database, human, meta search engine, prediction, protein, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Karlsruhe Institute of Technology; Karlsruhe; Germany
biotools:harvester, nif-0000-10169 https://bio.tools/harvester SCR_008017 Harvester IV 2026-02-15 09:19:41 1480
TDT-PC
 
Resource Report
Resource Website
TDT-PC (RRID:SCR_001116) TDT-PC software application, software resource Software program to compute the statistical power of the Transmission/Disequilibrium Test (TDT) analytically, based on the most accurate asymptotic algorithms up to date, and is applicable in very general situations, where different parental disease status, multiple children, mixed family type and recombination events are considered. Routine algorithms for Monte Carlo simulations with significant improvements are also implemented in this program. (entry from Genetic Analysis Software) gene, genetic, genomic, c++, ms-windows, ms-dos, unix, solaris, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
PMID:11443734 nlx_154677, biotools:tdt_power_calculator https://bio.tools/tdt_power_calculator SCR_001116 Transmission Disequilibrium Test Power Calculator, TDT Power Calculator 2026-02-15 09:18:03 0
LOCUSMAP
 
Resource Report
Resource Website
LOCUSMAP (RRID:SCR_000840) LOCUSMAP software application, software resource Software package designed for rapid linkage analysis and map construction of loci with a variety of inheritance modes. (entry from Genetic Analysis Software) gene, genetic, genomic, fortran 90/95, ms-windows, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154434, biotools:locusmap https://bio.tools/locusmap SCR_000840 2026-02-15 09:18:00 0
RightField
 
Resource Report
Resource Website
1+ mentions
RightField (RRID:SCR_002649) RightField software application, software resource An open-source tool for adding ontology term selection to Excel spreadsheets. It is used by a "Template Creator" to create semantically aware Excel spreadsheet templates. The Excel templates are then reused by Scientists to collect and annotate their data; without any need to understand, or even be aware of, RightField or the ontologies used. For each annotation field, RightField can specify a range of allowed terms from a chosen ontology (subclasses, individuals or combinations). The resulting spreadsheet presents these terms to the users as a simple drop-down list. This reduces the adoption barrier for using community ontologies as the annotation is made by the scientist that generated the data rather than a third party, and the annotation is collected at the time of data collection. RightField is a standalone Java application which uses Apache-POI for interacting with Microsoft documents. It enables users to import Excel spreadsheets, or generate new ones from scratch. Ontologies can either be imported from their local file systems, or from the BioPortal ontology repository. Individual cells, or whole columns or rows can be marked with the required ranges of ontology terms and an individual spreadsheet can be annotated with terms from multiple ontologies. annotation, semantic, ontology, term selection, excel, java, bio.tools is listed by: BioPortal
is listed by: FORCE11
is listed by: bio.tools
is listed by: Debian
is related to: SEEK
is related to: Workflow4Ever
has parent organization: University of Manchester; Manchester; United Kingdom
has parent organization: Heidelberg Institute for Theoretical Studies; Heidelberg; Germany
PMID:21622664 Free, Available for download, Freely available biotools:rightfield, nlx_156077 https://bio.tools/rightfield SCR_002649 2026-02-15 09:18:21 3
AltAnalyze - Alternative Splicing Analysis Tool
 
Resource Report
Resource Website
50+ mentions
AltAnalyze - Alternative Splicing Analysis Tool (RRID:SCR_002951) AltAnalyze software application, software resource Software application for microarry, RNA-Seq and metabolomics analysis. For splicing sensitive platforms (RNA-Seq or Affymetrix Exon, Gene and Junction arrays), it will assess alternative exon (known and novel) expression along protein isoforms, domain composition and microRNA targeting. In addition to splicing-sensitive platforms, it provides comprehensive methods for the analysis of other data (RMA summarization, batch-effect removal, QC, statistics, annotation, clustering, network creation, lineage characterization, alternative exon visualization, gene-set enrichement and more). AltAnalyze can be run through an intuitive graphical user interface or command-line and requires no advanced knowledge of bioinformatics programs or scripting. Alternative regulated exons can be subsequently visualized in the context of proteins, domains and microRNA binding sites with the Cytoscape Plugin DomainGraph. analysis, alternative splicing, microarray, calculate, pathway, ontology, domain, microrna, targeting, splicing, microarry, rna-seq, metabolomics, mac osx, windows, ubuntu, cross platform, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Cytoscape
has parent organization: University of California at San Francisco; California; USA
PMID:20513647 Free, Available for download, Freely available nif-0000-30083, OMICS_02250, biotools:altanalyze https://bio.tools/altanalyze SCR_002951 Alternative Splicing Analysis Tool 2026-02-15 09:18:25 81
cortex
 
Resource Report
Resource Website
100+ mentions
cortex (RRID:SCR_002467) cortex software application, software resource Software package with functions that will help researchers plan how many subjects per group need to be included in an MRI-based cortical thickness study to ensure a thickness difference is detected. The package requires cortical thickness mapping and co-registration to be carried out using Freesurfer. The power analyses are implemented in the R software package., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. clinical neuroinformatics, mgh/mgz, magnetic resonance, r, surface analysis, thickness, mri, cortical thickness, morphometry, neuroimaging, power analysis, study design, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: bio.tools
is listed by: Debian
has parent organization: Brain Research Institute
PMID:22807270 THIS RESOURCE IS NO LONGER IN SERVICE nlx_155842, biotools:cortex http://brain.org.au/software/cortex/power
http://www.nitrc.org/projects/cortex
https://bio.tools/cortex
SCR_002467 Sample Size Estimates for Well-Powered Cross-Sectional Cortical Thickness Studies 2026-02-15 09:18:18 374
Yabi
 
Resource Report
Resource Website
Yabi (RRID:SCR_005359) Yabi service resource, software resource A web-based analytical environment framework for bioinformatics applications that can be customized for a diverse range of -omics applications. The software system is adaptable to a range of both pluggable execution and data backends in an open source implementation. Enabling seamless and transparent access to heterogenous HPC environments at its core, it then provides an analysis workflow environment that can create and reuse workflows as well as manage large amounts of both raw and processed data in a secure and flexible way across geographically distributed compute resources. Yabi can be used via a web-based environment to drag-and-drop tools to create sophisticated workflows. It can also be accessed through the Yabi command line which is designed for users that are more comfortable with writing scripts or for enabling external workflow environments to leverage the features in Yabi. Configuring tools can be a significant overhead in workflow environments. Yabi greatly simplifies this task by enabling system administrators to configure as well as manage running tools via a web-based environment and without the need to write or edit software programs or scripts. grid computing, high performance computing, cloud computing, bioinformatics, pipeline, workflow, command line, python, linux, storage, compute, genomics, transcriptomics, proteomics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Murdoch University; Perth; Australia
PMID:22333270 GNU General Public License, v3 OMICS_01148, biotools:yabi https://bio.tools/yabi SCR_005359 2026-02-15 09:18:57 0
HAPLOCLUSTERS
 
Resource Report
Resource Website
HAPLOCLUSTERS (RRID:SCR_007439) HAPLOCLUSTERS software application, software resource Software program designed to detect excess haplotypes sharing in datasets consisting of case and control haplotypes. Excess haplotype sharing can be seen around disease loci in case samples since LD persists longer here than in the controls where LD is persisting only according to the relatedness of the individuals in the population, i.e. the age of the population. (entry from Genetic Analysis Software) gene, genetic, genomic, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
Aging nlx_154014, biotools:haploclusters https://bio.tools/haploclusters SCR_007439 2026-02-15 09:19:35 0
MULTIMAP
 
Resource Report
Resource Website
10+ mentions
MULTIMAP (RRID:SCR_007168) MULTIMAP software application, software resource Software program for automated construction of genetic maps (entry from Genetic Analysis Software) gene, genetic, genomic, lisp, unix, (sun/compaq-alpha/hp..), bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154013, biotools:multimap https://bio.tools/multimap http://compgen.rutgers.edu/Multimap/ SCR_007168 2026-02-15 09:19:29 27
SIBMED
 
Resource Report
Resource Website
1+ mentions
SIBMED (RRID:SCR_007495) SIBMED software application, software resource Software application that identifies likely genotyping errors and mutations for a sib pair in the context of multipoint mapping. (entry from Genetic Analysis Software) gene, genetic, genomic, fortran 77, ms-windows, unix, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
biotools:sibmed, nlx_154043 https://bio.tools/sibmed SCR_007495 SIBling Mutation and Error Detection 2026-02-15 09:19:46 1
COEUS
 
Resource Report
Resource Website
1+ mentions
COEUS (RRID:SCR_006287) COEUS software application, software resource A semantic web-powered knowledge management framework, aiming at a streamlined application development cycle and following a semantic web in a box approach. The framework provides a single package including advanced data integration and triplification tools, base ontologies, a web-oriented engine and a flexible exploration API. Resources can be integrated from heterogeneous sources, including CSV and XML files or SQL and SPARQL query results, and mapped directly to one or more ontologies. Advanced interoperability features include REST services, a SPARQL endpoint and LinkedData publication. These enable the creation of multiple applications for web, desktop or mobile environments, and empower a new knowledge federation layer. It is targeted at rapid application deployment of new applications in any research field, supported by a comprehensive integration engine and an advanced data distribution API. data integration, interoperability, ontology, semantic web, bioinformatics, biomedical, semantic web framework, rapid application deployment, linked data, web service, biomedical application, biomedical semantics, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Aveiro; Aveiro; Portugal
PMID:23244467 Open unspecified license biotools:coeus, nlx_151933 https://bio.tools/coeus SCR_006287 2026-02-15 09:19:13 6
PubCrawler
 
Resource Report
Resource Website
1+ mentions
PubCrawler (RRID:SCR_008235) service resource, software resource PubCrawler is a free alerting service that scans daily updates to the NCBI Medline (PubMed) and GenBank databases. PubCrawler helps keeping scientists informed of the current contents of Medline and GenBank, by listing new database entries that match their research interests. The free PubCrawler web service has been operating for five years and so far has brought literature and sequence updates to over 22 000 users. It provides information on a personalized web page whenever new articles appear in PubMed or when new sequences are found in GenBank that are specific to customized queries. The server also acts as an automatic alerting system by sending out short notifications or emails with the latest updates as soon as they become available. PubCrawler searches the NCBI PubMed (Medline) and Entrez (GenBank) databases daily using search parameters (keywords, author names, etc.) specified by the user. There is no limit on the number of searches that can be carried out. Previous search hits are stored and only the newest PubMed or GenBank records are shown each day. The results are presented as an HTML Web page, similar to the results of an NCBI PubMed or Entrez query. This Web page can be located on our computer (the PubCrawler WWW-Service), on your computer (the stand-alone program), or you can receive it via e-mail (set this up using the PubCrawler WWW-Service). The Web page sorts the results into groups of PubMed/GenBank entries that are zero-days-old, 1-day-old, 2-days-old, etc., up to a user-specified age limit. Sponsors: Development of PubCrawler was supported by EMBnet training tools, bio.tools is listed by: 3DVC
is listed by: bio.tools
is listed by: Debian
biotools:pubcrawler, nif-0000-21345 https://bio.tools/pubcrawler SCR_008235 PubCrawler 2026-02-15 09:19:29 9
ASPEX
 
Resource Report
Resource Website
1+ mentions
ASPEX (RRID:SCR_008414) ASPEX software application, software resource A set of programs for performing multipoint exclusion mapping of affected sibling pair data for discrete traits. (entry from Genetic Analysis Software) gene, genetic, genomic, c, tcl, perl, (the graphic script requires xmgr, available from ftp://ftp.teleport.com/pub/users/pturner/acegr), unix, (solaris/sunos/irix/osf-1), linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154234, biotools:aspex https://bio.tools/aspex SCR_008414 Affected Sib Pairs EXclusion map 2026-02-15 09:19:49 9
ALBERT
 
Resource Report
Resource Website
10+ mentions
ALBERT (RRID:SCR_009037) ALBERT software application, software resource Software application that estimates genotype relative risks, genotyping error rates and population risk allele frequencies from marker genotype data in case-parent trios. ALBERT uses the distribution of trio marker genotypes to compute maximum likelihood estimates for the parameters. (entry from Genetic Analysis Software) gene, genetic, genomic, c, unix, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
biotools:albert, nlx_154002 https://bio.tools/albert SCR_009037 A Likelihood Based Estimation of Risk in Trios 2026-02-15 09:20:01 47
FastTree
 
Resource Report
Resource Website
5000+ mentions
FastTree (RRID:SCR_015501) source code, software resource Source code that infers approximately-maximum-likelihood phylogenetic trees from alignments of nucleotide or protein sequences. It uses the Jukes-Cantor or generalized time-reversible (GTR) models of nucleotide evolution and the JTT, WAG, or LG models of amino acid evolution. phylogenetic tree, phylogenetic tree creation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: VeryFastTree
PMID:19377059
DOI:10.1371/journal.pone.0009490
biotools:fasttree, OMICS_14703 https://bio.tools/fasttree
https://sources.debian.org/src/fasttree/
SCR_015501 2026-02-15 09:20:54 5774
lme4
 
Resource Report
Resource Website
100+ mentions
lme4 (RRID:SCR_015654) source code, software resource Software R package. Fit linear and generalized linear mixed-effects models. The models and their components are represented using S4 classes and methods. The core computational algorithms are implemented using the 'Eigen' C++ library for numerical linear algebra and 'RcppEigen' "glue." linear mixed-effects model, s4 class, eigen c++ library, r package, r, bio.tools is listed by: CRAN
is listed by: bio.tools
is listed by: Debian
works with: R package: lmerTest
Free, Available for download biotools:lme4 https://cran.r-project.org/package=lme4
https://github.com/lme4/lme4/
https://bio.tools/lme4
SCR_015654 lme4, lme4.0, lme4: Linear Mixed-Effects Models using 'Eigen' and S4, lme4: Linear Mixed-Effects Models, R package: lme4 2026-02-15 09:21:35 327

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