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http://www.uab.edu/medicine/hrfdcc/cores

Core whose goals are to establish a national resource for clinical data, DNA, and tissue biopsies from human patients with HRFDs, develop algorithms to identify causative genetic mutations in HRFD patients and utilize a suite of new tools to assess the pathogenicity of sequence variants, and expand the portfolio of educational information and tools to encompass the HRFD spectrum of disorders.

Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Hepato-Renal Fibrocystic Diseases Translational Resource (RRID:SCR_015309) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/neph/obrien/digital

Core facility which develops and implements software and methods of image segmentation for fluorescence microscopy data.

Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Digital Image Analysis Core (RRID:SCR_015276) Copy   

•   Source: SciCrunch Registry

http://www.uab.edu/medicine/hrfdcc/cores/d

Core goals include to develop in vitro predictive assays to identify and characterize HRFD lead compounds, develop in vivo predictive translational HRFD models to enhance efficacy assessment in preclinical testing, and develop advanced HRFD-specific toxicology and safety screens.

Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Therapeutic Screening and Drug Development Resource (RRID:SCR_015314) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/neph/obrien/probe

Core facility which develops and characterizes methods for expressing fluorescent biosensors in the rodent kidney to be paried with intravital microscopy.

Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Probe Delivery Core (RRID:SCR_015274) Copy   

•   Source: SciCrunch Registry

http://www.dukekidneycenter.org/cores/clinical-and-translational-core

Core facility which investigates the connections between chronic kidney disease, cardiovascular disease, and hypertension. It focuses specifically on investigating the pathophysiology, epidemiology, and therapeutic response in on-going studies or existing datasets of one of the three diseases with the aim of relating data from individual diseases to each other.

Proper citation: Duke O'Brien Center for Kidney Research Clinical and Translational Core (RRID:SCR_015272) Copy   

•   Source: SciCrunch Registry

http://livercenter.yale.edu/core-facilities/clinical-translational-core.aspx

Core facility which aims to develop an infrastructure for patient-oriented research by streamlining regulatory and compliance processes, obtaining and storing high-quality samples linked to clinical information, offering consultation in the design and implementation of clinical trials, and supplying statistical expertise for interpreting clinical and translational data.

Proper citation: Yale Liver Center Clinical and Translational Core (RRID:SCR_015259) Copy   

•   Source: SciCrunch Registry

http://livercenter.yale.edu/core-facilities/cellular-molecular-physiology-core-facility.aspx

Core facility that provides technical expertise, equipment and personnel to Liver Center Investigators who wish to work with animal models of liver disease, isolated liver cells, or gene expression in liver tissue. The Cell Isolation sub-core isolates hepatocytes and non-parenchymal liver cells primarily from rat and mouse, while the Molecular Biology sub-core provides equipment and expertise to Liver Center members in a centralized facility.

Proper citation: Yale Liver Center Cellular and Molecular Physiology Core (RRID:SCR_015258) Copy   

•   Source: SciCrunch Registry

https://ww2.mc.vanderbilt.edu/DDRC/19909

Core facility whose services include training, acquisition and analysis on cytometers for experiments that include different fluorochromes, imaging cytometry, and mass cytometry.

Proper citation: Vanderbilt Digestive Disease Research Center Flow Cytometry Core (RRID:SCR_015251) Copy   

•   Source: SciCrunch Registry

https://ww2.mc.vanderbilt.edu/DDRC/6914

Core facility whose goals include furnishing professional guidance in experimental design and data interpretation and providing access to optical and electron microscopy. Its services include confocal microscopy, wide-field microscopy, transmission electron microscopy, and processing and embedment of tissue or cells for EM.

Proper citation: Vanderbilt Digestive Disease Research Center Cellular Imaging Core (RRID:SCR_015250) Copy   

•   Source: SciCrunch Registry

http://sph.unc.edu/norc/animal/

Core that offers technical support and expertise for measuring traits related to metabolism in mouse models of obesity and nutritionally relevant disease. It provides access to methods, equipment, and populations to support high quality and high throughput phenotyping of energy balance components in mice.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Animal Metabolism Phenotyping Core (RRID:SCR_015465) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/uwnorc/core-facilities/energy-balance-core/

Core that provides affiliated investigators with a resource for measuring energy balance and body composition in rodent models, and for applying neuroscience techniques to nutrition and obesity-related research.

Proper citation: University of Washington Nutrition and Obesity Research Center Energy Balance Core (RRID:SCR_015469) Copy   

•   Source: SciCrunch Registry

http://www.norc.uab.edu/corefacilities/animalmodels

Core that provides specialized expertise in the use of animal models and instrumentation to facilitate animal research related to nutrition and obesity.

Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Animal Models Core (RRID:SCR_015466) Copy   

•   Source: SciCrunch Registry

http://chaicore.com/home

Core that uses technologies to facilitate the translation of traditional evidence-based behavioral interventions into effective web- and mobile-based interventions in fields such as obesity and cancer prevention.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Communication for Health Applications and Interventions Core (RRID:SCR_015461) Copy   

•   Source: SciCrunch Registry

http://zfrhmaps.tch.harvard.edu/cemh/CoreB.htm

Zebrafish core facility which generates and maintains transgenic and mutant fish lines for hematology research. It also provides expertise and training in model production, study design, and fish production for research.

Proper citation: Boston Children's Hospital Center of Excellence in Molecular Hematology Zebrafish Core (RRID:SCR_015355) Copy   

•   Source: SciCrunch Registry

http://zfrhmaps.tch.harvard.edu/cemh/CoreC.htm

Core facility for basic and translational stem cell research. The core's areas of expertise include human pluripotent stem cell biology, cGMP cell manufacturing, reprogramming, genome editing, genotyping, laboratory automation, chemical screening, and imaging/image analysis.

Proper citation: Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core (RRID:SCR_015352) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10800/community_id/1418

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 6th,2023. Core whose objective is to provide investigators at Vanderbilt and outside institutions a means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations.

Proper citation: MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core (RRID:SCR_015353) Copy   

•   Source: SciCrunch Registry

http://mmoc.med.umich.edu/CoreIntegrativeBiostatisticsInformatics.php

Core facility whose services include expertise in experimental design and modeling for preclinical, clinical and translational research studies that integrate clinical, molecular, neurobehavioral and other phenotype data. It also offers support for data acquisition and analysis by the MMOC phenotyping Cores and Investigational Weight Management Clinic, expertise in database construction, maintenance and security relevant to investigators studies, and development and use of database and software tools for information organization and visualization of tightly-linked multiscale data for T1 translation of research knowledge relevant to obesity.

Proper citation: University of Michigan Nutrition and Obesity Research Center Integrative Biostatistics and Informatics Core (RRID:SCR_015478) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/uwnorc/core-facilities/administrative-and-enrichment-core/

Core that is responsible for the overall administrative coordination of the NORC. It also administers the Biostatistics Subcore, Pilot and Feasibility Program, and Enrichment Seminar Series.

Proper citation: University of Washington Nutrition and Obesity Research Center Administrative and Enrichment Core (RRID:SCR_015471) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/uwnorc/core-facilities/analytic-core/

Core that provides affiliated investigators with access to nutritional assays, new methods development, and consultation services. Services also include quantitative measures of nitrogen-containing compounds, carbohydrates and related compounds, lipids and related compounds, and more.

Proper citation: University of Washington Nutrition and Obesity Research Center Analytic Core (RRID:SCR_015470) Copy   

•   Source: SciCrunch Registry

http://sph.unc.edu/norc/administrative/

Core facility that is responsible for managing and organizing the activities of the internal governance committee and the external advisory board, promoting the techniques, methodologies, instrumentation, and resources offered by the core facilities, and supporting the integration of bioinformatics, biostatistics, clinical research, and metabolomics into clinical and translational research.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Administrative Core (RRID:SCR_015439) Copy   

•   Source: SciCrunch Registry