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https://ww2.mc.vanderbilt.edu/DDRC/6914

Core facility whose goals include furnishing professional guidance in experimental design and data interpretation and providing access to optical and electron microscopy. Its services include confocal microscopy, wide-field microscopy, transmission electron microscopy, and processing and embedment of tissue or cells for EM.

Proper citation: Vanderbilt Digestive Disease Research Center Cellular Imaging Core (RRID:SCR_015250) Copy   

•   Source: SciCrunch Registry

http://cihd.cores.utah.edu/mgd/

Core facility which provides custom TALEN and Crispr-Cas9 DNA nucleases to induce targeted mutations in a genomic region of interest. It also provides hardware, reagents, and expertise for optimizing and performing HRMA for genes of interest.

Proper citation: Center for Iron and Heme Disorders at the University of Utah Mutation Generation and Detection Core (RRID:SCR_015339) Copy   

•   Source: SciCrunch Registry

http://animalcare.umich.edu/business-services/germ-free-mouse-facility

Core that provides services to the University of Michigan community and can also ship germ-free mice to locations worldwide. Its projects include studies investigating inflammatory bowel disease and cancer, host microbiome interactions, infectious disease pathogenesis, and mammalian and bacterial metabolism.

Proper citation: MMPC-University of Michigan Medical School Animal Care and Germ-Free Mouse Core (RRID:SCR_015344) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/ICBM

Core facility which provides access to and training on optical microscopy instruments to Indiana University researchers.

Proper citation: Indiana University Cooperative Center of Excellence in Hematology Optical Microscopy Core (RRID:SCR_015347) Copy   

•   Source: SciCrunch Registry

http://www.cancer.iu.edu/research-trials/facilities/angiobiocore/index.shtml

Core facility which conducts validated and reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders.

Proper citation: Indiana University Cooperative Center of Excellence in Hematology Angiogenesis Core (RRID:SCR_015345) Copy   

•   Source: SciCrunch Registry

http://www.cancer.iu.edu/research-trials/facilities/flow-cytometry/index.shtml

Core facility which provides flow cytometry consultation, technical advice, flow cytometric analysis and cell sorting services as well as flow cytometric image analysis.

Proper citation: Indiana University School of Medicine Flow Cytometry Core Facility (RRID:SCR_015346) Copy   

•   Source: SciCrunch Registry

http://sharedresources.fredhutch.org/core-facilities/scientific-imaging

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Scientific imaging service that serves as a centralized facility for imaging and visualization. The core facility provides access to time lapse and 3-D microscopy and quantitative autoradiography.

Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Scientific Imaging (RRID:SCR_015340) Copy   

•   Source: SciCrunch Registry

http://medicine.yale.edu/labmed/ycceh/cores/core_d/index.aspx

Core facility which provides expertise, technical assistance, and mice for human-into-mouse xenotransplantation studies. Mouse models include MITRG-SKI (KnockIn) mice that express human cytokines and huSIRPa from the endogenous murine loci in the Rag-/- IL-2Ry -/- background. It also offers training and technical assistance in the study of hematopoiesis and benign hematologic questions in mice.

Proper citation: Yale Cooperative Center of Excellence in Hematology Animal Modeling Core (RRID:SCR_015349) Copy   

•   Source: SciCrunch Registry

http://zfrhmaps.tch.harvard.edu/cemh/CoreB.htm

Zebrafish core facility which generates and maintains transgenic and mutant fish lines for hematology research. It also provides expertise and training in model production, study design, and fish production for research.

Proper citation: Boston Children's Hospital Center of Excellence in Molecular Hematology Zebrafish Core (RRID:SCR_015355) Copy   

•   Source: SciCrunch Registry

http://zfrhmaps.tch.harvard.edu/cemh/CoreC.htm

Core facility for basic and translational stem cell research. The core's areas of expertise include human pluripotent stem cell biology, cGMP cell manufacturing, reprogramming, genome editing, genotyping, laboratory automation, chemical screening, and imaging/image analysis.

Proper citation: Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core (RRID:SCR_015352) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10800/community_id/1418

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 6th,2023. Core whose objective is to provide investigators at Vanderbilt and outside institutions a means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations.

Proper citation: MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core (RRID:SCR_015353) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/model_organisms.html

Core that uses the yeast S. cerevisiae and the zebrafish D. rerio to dissect fundamental aspects of kidney development and protein structure and function.

Proper citation: Pittsburgh Center for Kidney Research Model Organisms (RRID:SCR_015288) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/imaging_core.html

Core that provides qualitative and quantitative image analysis of the kidney and lower urinary tract through performing light and electron microscopic analysis of epithelial cells and tissues, quantifying and reconstructing kidney and lower urinary tract-associated tissues and organs in 3D, and visualizing and quantifying molecular and cellular dynamics in living animals.

Proper citation: Pittsburgh Center for Kidney Research Kidney Imaging (RRID:SCR_015289) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/obriencenter/cores/clinical-studies-of-aki-core

Core facility which provides investigators access to patients with AKI through an established international network of collaborating investigators. It also provides core resources to support the design and conduct of clinical research in AKI and genomics resources to perform systematic genomic analyses and allow correlation with clinical phenotypic information.

Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Clinical Studies of AKI (RRID:SCR_015287) Copy   

•   Source: SciCrunch Registry

http://sharedresources.fredhutch.org/core-facilities/comparative-medicine

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides a variety of animal housing, veterinary and research support services.

Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Comparative Medicine (RRID:SCR_015326) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/neph/obrien/biosensor

Core facility which develops, characterizes and validates fluorescence protein biosensors for intravital multiphoton microscopy.

Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Biosensor Development Core (RRID:SCR_015281) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/cell_physiology.html

Core that provides investigators with in vitro systems for the study of transport processes at the molecular, cell, and epithelial levels.

Proper citation: Pittsburgh Center for Kidney Research Cellular Physiology (RRID:SCR_015284) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/single_nephron_core.html

Core that offers functional (in vitro microperfusion of isolated segments, measurements of transepithelial ion/solute fluxes, fluorescence functional imaging of single tubular cells), biochemical (microassays of enzyme/transporter activity), molecular (quantitation and analysis of RNA and protein), and analytical (targeted renal metabolomics of interrelated networks of small molecules) strategies applied to microdissected tubules, single cells, and urinary exosomes to address relevant questions proposed by users. It also provides analytical services for determining concentrations of exogenous pharmacological agents and molecular probes achieved within the tissue of interest.

Proper citation: Pittsburgh Center for Kidney Research Single Nephron and Metabolomics (RRID:SCR_015285) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/obriencenter/cores/biostatistics-core

Core provides statistical expertise in the conceptualization and design of projects, expertise in data management for the resulting clinical and bioinformatics data, and assistance with the preparation of project reports, presentations and manuscripts.

Proper citation: University of Alabama at Birmingham-University of California San Diego O'Brien Center for Acute Kidney Injury Research Biostatistical Core (RRID:SCR_015283) Copy   

•   Source: SciCrunch Registry

http://sharedresources.fredhutch.org/core-facilities/genomics

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides expertise and support for generating genomics-based data. Services for DNA arrays, genetic analysis, and high-throughput screening are provided through three specialized laboratories.

Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Genomics Shared Resource (RRID:SCR_015327) Copy   

•   Source: SciCrunch Registry