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https://edspace.american.edu/openbehavior/project/pycro-manager/

Open source software for customized and reproducible microscope control. Software Python package that enables control of micro-manager as well as development of customized experiments integrated with real-time image processing.

Proper citation: Pycro Manager (RRID:SCR_022356) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/cellpose/

Software tool as generalist algorithm for cell and nucleus segmentation.

Proper citation: Cellpose (RRID:SCR_022332) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/compass/

Non invasive, infrared activity and sleep measurement system that uses passive infrared sensors and Arduino microprocessor. Publication provides protocol for assembling COMPASS as well as provides support protocols and python scripts for data analysis, best practices for optimum results, troubleshooting, and alternative protocols for different use scenarios.

Proper citation: COMPASS (RRID:SCR_022329) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/brainrender/

Software Python package for visualizing and interacting with datasets registered to brain atlases. Used for visualization of neuroanatomical and morphological data.

Proper citation: Brainrender (RRID:SCR_022328) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/tetrodrive/

3D printed microdrive for electrophysiology and optophysiology. Consists of main body and head. Used for in vivo tetrode recording, optical imaging, and optogenetic manipulation in freely moving mice.Design files and build instructions for this device can be found on TetrODrive GitHub.Microdrive can be assembled in 15 min and price for all materials, including 3D printer, is lower than single commercial microdrive.

Proper citation: TetrODrive (RRID:SCR_022326) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/frost/

Open source system built around Arduino based microcontroller for analog and digital input and synchronization combined with custom printed circuit board. Hardware and Arduino-based firmware used to synchronize experimental and electrophysiological data.

Proper citation: Florida research open source synchronization tool (RRID:SCR_022344) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/vocalmat/

Software MATLAB based toolbox for automated quantitative analysis of ultrasonic vocalizations. Utilizes image processing libraries to detect USVs and computational vision and machine learning algorithms to classify detected USVs. Used for analysis of ultrasonic vocalizations from mice using computer vision and machine learning.

Proper citation: VocalMat (RRID:SCR_022342) Copy   

•   Source: SciCrunch Registry

https://cran.r-project.org/web/packages/permuco/index.html

Software R package for permutation test in linear model with nuisances variables.Used for permutation testing in regression, ANOVA, and comparison of signals.

Proper citation: Permuco (RRID:SCR_022341) Copy   

•   Source: SciCrunch Registry

https://github.com/ACCLAB/DABEST-python

Software package for data analysis using bootstrap coupled estimation. Library combining Python, R, and MATLAB for estimation statistics.

Proper citation: DABEST (RRID:SCR_022340) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/gazemetrics/

Software tool for data extraction and computation of spatial accuracy and precision of head mounted display based eye trackers. Allows for significant customization without altering source code but changes to the code allow for further alteration.

Proper citation: GazeMetrics (RRID:SCR_022338) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/pyos-5/

Open source operant box system optimized for use with tethered animals. System includes hardware and software. Control electronics are build on pyControl, controlling custom PCB integrating 5 infra-red break-beam sensors and 5 stimulus LEDs, single nose-poke for reward receptacle, stepper motor for control of custom peristaltic pump for reward delivery, audio board for tone generation through attached speaker, house light and fan, LED driver for optogenetic stimulation, and bidirectional communication with external devices via TTL pulses.

Proper citation: pyOS-5 project (RRID:SCR_022335) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/?s=pyPhotometry

Open source Python based hardware and software for fiber photometry data acquisition. System includes compact, low cost, data acquisition board built around Micropython microcontroller, and cross platform graphical user interface for controlling acquisition and visualising signals. Can acquire two analog and two digital signals, and control two external LEDs via built in LED drivers. Time division multiplexed illumination allows independent readout of fluorescence evoked by different excitation wavelengths from single photoreceiver signal.

Proper citation: pyPhotometry (RRID:SCR_022940) Copy   

•   Source: SciCrunch Registry

https://github.com/BadenLab/LED-Zappelin

Open source LED controller for arbitrary spectrum visual stimulation and optogenetics during 2 photon imaging. Device that rapidly time interleaves stimulation and detection epochs during two photon imaging.

Proper citation: LED Zappelin’ (RRID:SCR_022560) Copy   

•   Source: SciCrunch Registry

https://github.com/MatsumotoJ/usvcam

Open source acoustic camera system for measuring ultrasound communication in rodents. System includes small phased microphone array combined with camera and comprises USV segmentation algorithms with modification for overlapping vocalizations that results in high accuracy. Enables simpler and faster USV localization and assignment.

Proper citation: USVCAM (RRID:SCR_022747) Copy   

•   Source: SciCrunch Registry

https://github.com/denisecailab/minian

Software miniscope analysis pipeline that requires low memory and computational demand so it can be run without specialized hardware. Offers interactive visualization that allows users to see how parameters in each step of pipeline affect output.

Proper citation: Minian (RRID:SCR_022601) Copy   

•   Source: SciCrunch Registry

https://github.com/TAMUCogLab/OpenSync

Open source platform for synchronizing multiple behavioral and physiological signals in neuroscience experiments.

Proper citation: OpenSync (RRID:SCR_022722) Copy   

•   Source: SciCrunch Registry

https://github.com/compsy/ACTman/

Software R library to automate labor intensive actigraphy data preprocessing and analyses steps while improving transparency, reproducibility, and scalability over software suites traditionally used in actigraphy research practice. Provides streamlined preprocessing while validating circadian rhythm and sleep analysis.

Proper citation: ACTman (RRID:SCR_023119) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/nerd/

Portal provides open source neural recording device for wireless transmission of local field potential data in freely behaving animals. Used for electrophysiological recording of local field potentials in freely behaving animals.

Proper citation: NeRD (RRID:SCR_021582) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/ninscope/

Portal provides miniscope for fluorescence imaging and optogenetic stimulation. Used for monitoring of neural signals during unrestrained behavior.

Proper citation: NINscope (RRID:SCR_021577) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/3d-printed-headcap-microdrive/

Portal provides novel head cap and microdrive design for chronic multi electrode recordings in rats through use of 3D printing technology. Head cap and microdrive designs can be fabricated at little cost using consumer grade 3D printers.

Proper citation: 3D Printed Headcap and Microdrive (RRID:SCR_021595) Copy   

•   Source: SciCrunch Registry