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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
BEADS
 
Resource Report
Resource Website
10+ mentions
BEADS (RRID:SCR_013229) BEADS software resource Software for a normalization scheme that corrects nucleotide composition bias, mappability variations and differential local DNA structural effects in deep sequencing data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: University of Cambridge; Cambridge; United Kingdom
PMID:21646344 OMICS_00466, biotools:beads https://bio.tools/beads SCR_013229 BEADS: Bias Elimination Algorithm for Deep Sequencing, Bias Elimination Algorithm for Deep Sequencing 2026-02-14 02:02:50 37
Trans-ABySS
 
Resource Report
Resource Website
50+ mentions
Trans-ABySS (RRID:SCR_013322) Trans-ABySS software resource A software pipeline for analyzing ABySS-assembled contigs from shotgun transcriptome data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
OMICS_01326, biotools:trans-abyss https://bio.tools/trans-abyss/ SCR_013322 2026-02-14 02:02:47 69
chimerascan
 
Resource Report
Resource Website
50+ mentions
chimerascan (RRID:SCR_013298) chimerascan software resource Software package that detects gene fusions in paired-end RNA sequencing (RNA-Seq) datasets. Used for detection of chimeric transcripts in high-throughput sequencing data. Gene fusion detection, paired-end RNA sequencing data, RNA sequencing data, chimeric transcripts detection, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:chimerascan, OMICS_01343 https://bio.tools/chimerascan SCR_013298 2026-02-14 02:02:29 53
Pairwise Conservation Scores - An Algorithm to Identify Conserved K-mers
 
Resource Report
Resource Website
1+ mentions
Pairwise Conservation Scores - An Algorithm to Identify Conserved K-mers (RRID:SCR_013409) PCS software resource A stand-alone package to identify and analyze conserved k-mers in pairwise alignment. This program shows high performance for identifying miRNA seed binding sites in 3''-UTRs. perl, perl script, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Tsinghua University; Beijing; China
biotools:pcs, nlx_33020 https://bio.tools/pcs http://bioinfo.au.tsinghua.edu.cn/member/~gujin/pcs/ SCR_013409 Pairwise Conservation Scores 2026-02-14 02:02:51 3
CNV-seq
 
Resource Report
Resource Website
100+ mentions
CNV-seq (RRID:SCR_013357) CNV-seq software resource A method for detecting DNA copy number variation (CNV) using high-throughput sequencing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:cnv-seq, OMICS_00339 https://bio.tools/cnv-seq SCR_013357 2026-02-14 02:02:51 167
DISEASES
 
Resource Report
Resource Website
500+ mentions
DISEASES (RRID:SCR_015664) data or information resource, database Database that integrates evidence on disease-gene associations from automatic text mining, manually curated literature, cancer mutation data, and genome-wide association studies. It also assigns confidence scores that facilitate comparison of the different types and sources of evidence. disease, gene, disease-gene association, text-mining, , bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation Center for Protein Research NNF14CC0001;
European Union Seventh Framework Programme n259348
PMID:25484339 biotools:diseases https://bio.tools/diseases SCR_015664 2026-02-14 02:02:52 627
WebGeSTer DB
 
Resource Report
Resource Website
1+ mentions
WebGeSTer DB (RRID:SCR_002165) WebGeSTer DB data or information resource, database Database of intrinsic terminators of transcription that is comprized of >2,200,000 bacterial terminators identified from a total of 2036 chromosomes and 1508 plasmids. Information about structural parameters of individual terminators such as sequence, length of stem and loop, mismatches and gaps, U-trail, genomic coordinates and gene name and accession number is available in both tabular form and as a composite figure. Summary statistics for terminator profiles of whole genome can be also obtained. Raw data files for individual genomes can be downloaded (.zip files) for detailed investigations. Data is organized into different tiers such that users can fine-tune their search by entering name of the species, or taxon ID or genomes with a certain number of terminators. To visualize the occurrence of the terminators, an interactive map, with the resolution to single gene level, has been developed. genome, terminator, transcription, plasmid, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:20972211 THIS RESOURCE IS NO LONGER IN SERVICE biotools:webgester_db, OMICS_01862 https://bio.tools/webgester_db SCR_002165 WebGesTer Database, Web Genome Scannner for Terminators Database, WebGeSTer DB - A Transcription Terminator Database 2026-02-14 02:06:08 5
PubGene
 
Resource Report
Resource Website
10+ mentions
PubGene (RRID:SCR_002119) data or information resource, database It helps users retrieve information on genes and proteins. The underlying structure of PubGene can be viewed as a gene-centric database. Gene and protein names are cross-referenced to each other and to terms that are relevant to understanding their biological function, importance in disease and relationship to chemical substances. The result is a literature network organizing information in a form that is easy to navigate. gene, information, protein, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is parent organization of: Coremine Medical
Free, Freely Available biotools:pubgene, nif-0000-20908 https://bio.tools/pubgene SCR_002119 PubGene 2026-02-14 02:06:07 39
COSMIC - Catalogue Of Somatic Mutations In Cancer
 
Resource Report
Resource Website
1000+ mentions
COSMIC - Catalogue Of Somatic Mutations In Cancer (RRID:SCR_002260) COSMIC data or information resource, database Database to store and display somatic mutation information and related details and contains information relating to human cancers. The mutation data and associated information is extracted from the primary literature. In order to provide a consistent view of the data a histology and tissue ontology has been created and all mutations are mapped to a single version of each gene. The data can be queried by tissue, histology or gene and displayed as a graph, as a table or exported in various formats.
Some key features of COSMIC are:
* Contains information on publications, samples and mutations. Includes samples which have been found to be negative for mutations during screening therefore enabling frequency data to be calculated for mutations in different genes in different cancer types.
* Samples entered include benign neoplasms and other benign proliferations, in situ and invasive tumours, recurrences, metastases and cancer cell lines.
cancer, mutation, somatic mutation, tumor, cancer genome, genome, gene, dna, tissue, histology, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Cancer Wellcome Trust 077012/Z/05/Z PMID:20952405 Free nif-0000-02690, biotools:cosmic, OMICS_00082 http://www.sanger.ac.uk/perl/CGP/cosmic
https://bio.tools/cosmic
SCR_002260 Catalogue Of Somatic Mutations In Cancer 2026-02-14 02:06:06 4486
EchoBASE
 
Resource Report
Resource Website
1+ mentions
EchoBASE (RRID:SCR_002430) EchoBASE data or information resource, database A database that curates new experimental and bioinformatic information about the genes and gene products of the model bacterium Escherichia coli K-12 strain MG1655. It has been created to integrate information from post-genomic experiments into a single resource with the aim of providing functional predictions for the 1500 or so gene products for which we have no knowledge of their physiological function. While EchoBASE provides a basic annotation of the genome, taken from other databases, its novelty is in the curation of post-genomic experiments and their linkage to genes of unknown function. Experiments published on E. coli are curated to one of two levels. Papers dealing with the determination of function of a single gene are briefly described, while larger dataset are actually included in the database and can be searched and manipulated. This includes data for proteomics studies, protein-protein interaction studies, microarray data, functional genomic approaches (looking at multiple deletion strains for novel phenotypes) and a wide range of predictions that come out of in silico bioinformatic approaches. The aim of the database is to provide hypothesis for the functions of uncharacterized gene products that may be used by the E. coli research community to further our knowledge of this model bacterium. gene, bio.tools is listed by: bio.tools
is listed by: Debian
GlaxoSmithKline ;
BBSRC
PMID:15608209 nif-0000-02781, biotools:echobase, r3d100011646 https://bio.tools/echobase
https://doi.org/10.17616/R38W6H
SCR_002430 EchoBASE: an integrated post-genomic database for Escherichia coli 2026-02-14 02:06:10 6
Autophagy Database
 
Resource Report
Resource Website
10+ mentions
Autophagy Database (RRID:SCR_002671) Autophagy DB, AutophagyDB data or information resource, database Database that provides basic, up-to-date information on relevant literature, and a list of autophagy-related proteins and their homologs in eukaryotes. autophagy, protein, homolog, ortholog, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tokyo; Tokyo; Japan
Japanese Ministry of Education Culture Sports Science and Technology MEXT PMID:20972215 Free, Available for download, Freely available OMICS_03306, biotools:the_autophagy_database, r3d100012565 https://bio.tools/the_autophagy_database
https://doi.org/10.17616/R3J786
SCR_002671 2026-02-14 02:05:48 17
DOMINE: Database of Protein Interactions
 
Resource Report
Resource Website
1+ mentions
DOMINE: Database of Protein Interactions (RRID:SCR_002399) DOMINE data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 13,2026. Database of known and predicted protein domain (domain-domain) interactions containing interactions inferred from PDB entries, and those that are predicted by 8 different computational approaches using Pfam domain definitions. DOMINE contains a total of 26,219 domain-domain interactions (among 5,410 domains) out of which 6,634 are inferred from PDB entries, and 21,620 are predicted by at least one computational approach. Of the 21,620 computational predictions, 2,989 interactions are high-confidence predictions (HCPs), 2,537 interactions are medium-confidence predictions (MCPs), and the remaining 16,094 are low-confidence predictions (LCPs). (May 2014) domain-domain interaction, prediction, protein domain, interaction, protein domain interaction, protein, domain, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: Pfam
has parent organization: University of Texas at Dallas; Texas; USA
PMID:21113022
PMID:17913741
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01906, nif-0000-02758, biotools:domine https://bio.tools/domine SCR_002399 Database of Protein Domain Interactions 2026-02-14 02:06:07 1
Nucleic Acid Database
 
Resource Report
Resource Website
10+ mentions
Nucleic Acid Database (RRID:SCR_003255) NDB data or information resource, database A database of three-dimensional structural information about nucleic acids and their complexes. In addition to primary data, it contains derived geometric data, classifications of structures and motifs, standards for describing nucleic acid features, as well as tools and software for the analysis of nucleic acids. A variety of search capabilities are available, as are many different types of reports. NDB maintains the macromolecular Crystallographic Information File (mmCIF). nucleic acid, dna, nucleopeptide, nucleoprotein, nucleotide, rna, transfection, sequence, structure, function, bio.tools, FASEB list is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: MINAS - Metal Ions in Nucleic AcidS
is related to: Biological Magnetic Resonance Data Bank (BMRB)
is related to: Jenalib: Jena Library of Biological Macromolecules
has parent organization: Rutgers University; New Jersey; USA
NSF ;
DOE ;
NIH
PMID:24185695
PMID:1384741
Free, Available for download, Freely available nif-0000-03184, biotools:ndb, r3d100010415 https://bio.tools/ndb
https://doi.org/10.17616/R3531R
SCR_003255 2026-02-14 02:05:49 36
RefSeq
 
Resource Report
Resource Website
10000+ mentions
RefSeq (RRID:SCR_003496) data or information resource, database Collection of curated, non-redundant genomic DNA, transcript RNA, and protein sequences produced by NCBI. Provides a reference for genome annotation, gene identification and characterization, mutation and polymorphism analysis, expression studies, and comparative analyses. Accessed through the Nucleotide and Protein databases. reference sequence, transcript, protein, dna, rna, plasmid, organelle, virus, genome, nucleic acid, ortholog, paralog, haplotype, nucleotide sequence, gene expression, blast, gold standard, bio.tools is listed by: OMICtools
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: BeetleBase
is related to: EcoGene
is related to: INSDC
is related to: HFV Database
is related to: RefSeqGene
is related to: NCBI Protein Database
is related to: RefSeqGene
is related to: UniParc at the EBI
is related to: NCBI Nucleotide
is related to: UniParc
is related to: ProRepeat
is related to: NCBI Virus
is related to: Codon and Codon-Pair Usage Tables
is related to: RefSeq non-redundant proteins
has parent organization: NCBI
PMID:24316578
PMID:24259432
PMID:22121212
PMID:18927115
PMID:17130148
PMID:15608248
Free, Available for download, Freely available SCR_016579, nif-0000-03397, OMICS_01659, biotools:refseq, r3d100011306 ftp://ftp.ncbi.nlm.nih.gov/refseq
https://bio.tools/refseq
https://doi.org/10.17616/R3HP70
SCR_003496 RefSeq, , Reference Sequence Database, Reference Sequence, Reference Sequences, NCBI 2026-02-14 02:05:50 18049
MutDB
 
Resource Report
Resource Website
10+ mentions
MutDB (RRID:SCR_003251) data or information resource, database Database with annotations for human variation data with protein structural information and other functionally relevant information, if available. The mutations are organized by gene. web database, annotation database, human genome, human protein, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Buck Institute; California; USA
PMID:15980479 Free, Freely available biotools:mutdb, nif-0000-03173 https://bio.tools/mutdb SCR_003251 2026-02-14 02:06:11 10
PolymiRTS
 
Resource Report
Resource Website
100+ mentions
PolymiRTS (RRID:SCR_003389) PolymiRTS data or information resource, database Database of naturally occurring DNA variations in microRNA (miRNA) seed regions and miRNA target sites. MicroRNAs pair to the transcripts of protein-coding genes and cause translational repression or mRNA destabilization. SNPs and INDELs in miRNAs and their target sites may affect miRNA-mRNA interaction, and hence affect miRNA-mediated gene repression. The PolymiRTS database was created by scanning 3'UTRs of mRNAs in human and mouse for SNPs and INDELs in miRNA target sites. Then, the potential downstream effects of these polymorphisms on gene expression and higher-order phenotypes are identified. Specifically, genes containing PolymiRTSs, cis-acting expression QTLs, and physiological QTLs in mouse and the results of genome-wide association studies (GWAS) of human traits and diseases are linked in the database. The PolymiRTS database also includes polymorphisms in target sites that have been supported by a variety of experimental methods and polymorphisms in miRNA seed regions. polymorphism, microrna, human, disease, trait, snp, indel, pathway, genetic variant, gene expression, phenotype, chromosome, chromosome location, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tennessee Health Science Center; Tennessee; USA
PhRMA Foundation ;
UT Center for Integrative and Translational Genomics ;
NICHD HD052472;
NIAAA AA014425;
NIDA DA021131;
NINR NR009270;
NIAID AI081050;
NIAID AI019782;
American Heart Association 0830134N;
United States Department of Defense W81XHW-05-01-0227
PMID:24163105
PMID:22080514
Free, Available for download, Freely available nif-0000-03324, biotools:polymirts, OMICS_00391 https://bio.tools/polymirts http://compbio.utmem.edu/miRSNP/ SCR_003389 Polymorphism in microRNA Target Site, PolymiRTS Database, Polymorphism in microRNAs and their TargetSites 2026-02-14 02:06:12 149
PHI-base
 
Resource Report
Resource Website
100+ mentions
PHI-base (RRID:SCR_003331) PHI-base data or information resource, database Database that catalogs experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. It is an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, it also includes antifungal compounds and their target genes. Each entry is curated by domain experts and is supported by strong experimental evidence (gene disruption experiments, STM etc), as well as literature references in which the original experiments are described. Each gene is presented with its nucleotide and deduced amino acid sequence, as well as a detailed description of the predicted protein's function during the host infection process. To facilitate data interoperability, genes have been annotated using controlled vocabularies and links to external sources (Gene Ontology terms, EC Numbers, NCBI taxonomy, EMBL, PubMed and FRAC). gene expression, pathogenic bacteria, virulence, infection, target site, gene, pathogen-host interaction, interaction, phenotype, pathogen, disease, host, anti-infective, nucleotide sequence, amino acid sequence, bio.tools, FASEB list is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
BBSRC BB/1000488/1 PMID:17942425
PMID:17153929
PMID:16381911
Free, Freely available nif-0000-03276, r3d100011301, biotools:phi-base https://bio.tools/phi-base
https://doi.org/10.17616/R35D1V
http://www4.rothamsted.bbsrc.ac.uk/phibase/ SCR_003331 Pathogen Host Interaction base, Pathogen Host Interaction, Pathogen Host Interaction-Base 2026-02-14 02:05:43 198
MiST - Microbial Signal Transduction database
 
Resource Report
Resource Website
10+ mentions
MiST - Microbial Signal Transduction database (RRID:SCR_003166) MiST data or information resource, database Database which contains the signal transduction proteins for complete and draft bacterial and archaeal genomes. The MiST2 database identifies and catalogs the repertoire of signal transduction proteins in microbial genomes. signal transduction proteins, bacterial genome, archaeal genome, microbial genome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tennessee Knoxville; Tennessee; USA
South Carolina Research Association ;
DOE Office of Science ;
NIH ;
NIGMS GM083177
PMID:19900966 Free, Freely available biotools:mist, nif-0000-03140 https://bio.tools/mist SCR_003166 MiST 2.2, Microbial Signal Transduction Database, Microbial Signal Transduction database (MiST), MiST2 2026-02-14 02:06:11 31
SIDER
 
Resource Report
Resource Website
100+ mentions
SIDER (RRID:SCR_004321) SIDER data or information resource, database Database containing information on marketed medicines and their recorded adverse drug reactions. The information is extracted from public documents and package inserts. The available information include side effect frequency, drug and side effect classifications as well as links to further information, for example drug-target relations. The SIDER Side Effect Resource represents an effort to aggregate dispersed public information on side effects. To our knowledge, no such resource exist in machine-readable form despite the importance of research on drugs and their effects. The creation of this resource was motivated by the many requests for data that we received related to our paper (Campillos, Kuhn et al., Science, 2008, 321(5886):263-6.) on the utilization of side effects for drug target prediction. Inclusion of side effects as readouts for drug treatment should have many applications and we hope to be able to enhance the respective research with this resource. You may browse the drugs by name, browse the side effects by name, download the current version of SIDER, or use the search interface. medicine, drug, side effect, adverse drug reaction, drug-target, phenotype, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Allen Institute Neurowiki
has parent organization: European Molecular Biology Laboratory
PMID:20087340 Except as otherwise noted, Creative Commons Attribution-NonCommercial-ShareAlike License, v3, Commercial use requires permission r3d100012791, nlx_33359, OMICS_01588, biotools:sider https://bio.tools/sider
https://doi.org/10.17616/R3J226
SCR_004321 Side Effect Resource, SIDER: Side Effect Resource 2026-02-14 02:05:51 372
SGD
 
Resource Report
Resource Website
1000+ mentions
SGD (RRID:SCR_004694) SGD, SGD LOCUS, SGD REF data or information resource, database A curated database that provides comprehensive integrated biological information for Saccharomyces cerevisiae along with search and analysis tools to explore these data. SGD allows researchers to discover functional relationships between sequence and gene products in fungi and higher organisms. The SGD also maintains the S. cerevisiae Gene Name Registry, a complete list of all gene names used in S. cerevisiae which includes a set of general guidelines to gene naming. Protein Page provides basic protein information calculated from the predicted sequence and contains links to a variety of secondary structure and tertiary structure resources. Yeast Biochemical Pathways allows users to view and search for biochemical reactions and pathways that occur in S. cerevisiae as well as map expression data onto the biochemical pathways. Literature citations are provided where available. database, yeast, pathway, analysis, gene, nomenclature, predicted sequence, fungi, functional relationship, protein structure, bio.tools, FASEB list uses: InterMOD
is used by: NIF Data Federation
is used by: PhenoGO
is listed by: re3data.org
is listed by: OMICtools
is listed by: InterMOD
is listed by: bio.tools
is listed by: Debian
is affiliated with: InterMOD
is related to: AmiGO
is related to: Yeast Search for Transcriptional Regulators And Consensus Tracking
is related to: HomoloGene
is related to: TXTGate
is related to: PhenoGO
has parent organization: Stanford University School of Medicine; California; USA
has parent organization: Stanford University; Stanford; California
is parent organization of: Ascomycete Phenotype Ontology
is parent organization of: SGD Gene Ontology Slim Mapper
NHGRI 5P41HG001315-11;
NHGRI 5P41HG002273-05;
NHGRI 5U41HG001315-18;
NHGRI 2U41HG002273-13;
NHGRI 5R01HG004834-04
PMID:24265222
PMID:12519985
PMID:9399804
Free for academic use, The community can contribute to this resource, Non-commercial nif-0000-03456, biotools:sgd, r3d100010419, OMICS_01661 https://bio.tools/sgd
https://doi.org/10.17616/R3N313
http://genome-www.stanford.edu/Saccharomyces/ SCR_004694 SGD LOCUS, Saccharomyces Genome Database, SGD REF 2026-02-14 02:06:21 1920

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