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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Piano
 
Resource Report
Resource Website
100+ mentions
Piano (RRID:SCR_003200) data analysis software, software resource, data processing software, software application Software R-package for running gene set analysis using various statistical methods, from different gene level statistics and a wide range of gene-set collections. The Piano package contains functions for combining the results of multiple runs of gene set analyses. r, omics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chalmers University of Technology; Gothenburg; Sweden
has parent organization: Bioconductor
PMID:23444143 Free, Available for download, Freely available OMICS_01558, biotools:piano https://bio.tools/piano SCR_003200 2026-02-14 02:00:42 182
Solas
 
Resource Report
Resource Website
1+ mentions
Solas (RRID:SCR_003168) sequence analysis software, data processing software, data analysis software, source code, software application, software resource Software package for the statistical language R, devoted to the analysis of next generation short read data of RNA-seq transcripts. It provides predictions of alternative exons in a single condition/cell sample, predictions of differential alternative exons between two conditions/cell samples, and quantification of alternative splice forms in a single condition/cell sample. r statistical package, rna seq, exon prediction, exon splicing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: R Project for Statistical Computing
has parent organization: Max Planck Institute for Molecular Genetics; Berlin; Germany
Free, Available for download, Freely available biotools:solas, OMICS_01339 https://bio.tools/solas SCR_003168 2026-02-14 02:00:23 8
GenePattern
 
Resource Report
Resource Website
1000+ mentions
GenePattern (RRID:SCR_003201) GenePattern data analysis software, software resource, data processing software, software application A powerful genomic analysis platform that provides access to hundreds of tools for gene expression analysis, proteomics, SNP analysis, flow cytometry, RNA-seq analysis, and common data processing tasks. A web-based interface provides easy access to these tools and allows the creation of multi-step analysis pipelines that enable reproducible in silico research. gene expression, analysis, genomic, pattern, proteomics, silico, snp, workflow, analysis pipeline, flow cytometry, rna-seq, data processing, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is affiliated with: GenePattern Notebook
is related to: TIGRESS
has parent organization: Broad Institute
NCI ;
NIGMS
PMID:16642009 Free, Freely available biotools:genepattern, OMICS_01855, nif-0000-30654 https://bio.tools/genepattern SCR_003201 2026-02-14 02:00:23 1078
PIRSF
 
Resource Report
Resource Website
10+ mentions
PIRSF (RRID:SCR_003352) PIRSF data or information resource, narrative resource, database, standard specification A SuperFamily classification system, with rules for functional site and protein name, to facilitate the sensible propagation and standardization of protein annotation and the systematic detection of annotation errors. The PIRSF concept is being used as a guiding principle to provide comprehensive and non-overlapping clustering of UniProtKB sequences into a hierarchical order to reflect their evolutionary relationships. The PIRSF classification system is based on whole proteins rather than on the component domains; therefore, it allows annotation of generic biochemical and specific biological functions, as well as classification of proteins without well-defined domains. There are different PIRSF classification levels. The primary level is the homeomorphic family, whose members are both homologous (evolved from a common ancestor) and homeomorphic (sharing full-length sequence similarity and a common domain architecture). At a lower level are the subfamilies which are clusters representing functional specialization and/or domain architecture variation within the family. Above the homeomorphic level there may be parent superfamilies that connect distantly related families and orphan proteins based on common domains. Because proteins can belong to more than one domain superfamily, the PIRSF structure is formally a network. The FTP site provides free download for PIRSF. protein annotation, classification, protein, superfamily, functional site, protein name, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: UniProtKB
has parent organization: Protein Information Resource
NHGRI U01-HG02712;
NSF DBI-0138188;
NSF ITR-0205470
PMID:19455212
PMID:14681371
Free, Freely available biotools:pirsf, nif-0000-03294, OMICS_01697 https://bio.tools/pirsf http://pir.georgetown.edu/pirsf/ SCR_003352 PIR SuperFamily, Protein Information Resource SuperFamily 2026-02-14 02:00:46 28
ALDEx2
 
Resource Report
Resource Website
500+ mentions
ALDEx2 (RRID:SCR_003364) software resource Software tool to examine compositional high-throughput sequence data with Welch's t-test. A differential relative count abundance analysis for the comparison of two conditions. For example, single-organism and meta-rna-seq high-throughput sequencing assays, or of selected and unselected values from in-vitro sequence selections. Uses a Dirichlet-multinomial model to infer abundance from counts, that has been optimized for three or more experimental replicates. Infers sampling variation and calculates the expected Benjamini-Hochberg false discovery rate given the biological and sampling variation using several parametric and non-parametric tests. Can to glm and Kruskal-Wallace tests on one-way ANOVA style designs. standalone software, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: aldex
has parent organization: Western University; Ontario; Canada
PMID:24910773 Free, Available for download, Freely available biotools:aldex2, OMICS_04634 https://bio.tools/aldex2 SCR_003364 2026-02-14 02:00:32 529
ggbio
 
Resource Report
Resource Website
10+ mentions
ggbio (RRID:SCR_003313) software resource An R package for extending the grammar of graphics for genomic data. The graphics are designed to answer common scientific questions, in particular those often asked of high throughput genomics data. All core Bioconductor data structures are supported, where appropriate. The package supports detailed views of particular genomic regions, as well as genome-wide overviews. Supported overviews include ideograms and grand linear views. High-level plots include sequence fragment length, edge-linked interval to data view, mismatch pileup, and several splicing summaries. standalone software, unix/linux, mac os x, windows, r, infrastructure, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:22937822 Free, Available for download, Freely available biotools:ggbio, OMICS_04660 http://www.tengfei.name/ggbio/
https://bio.tools/ggbio
SCR_003313 ggbio - Visualization tools for genomic data 2026-02-14 02:00:45 14
deFuse
 
Resource Report
Resource Website
50+ mentions
deFuse (RRID:SCR_003279) sequence analysis software, data processing software, data analysis software, software toolkit, software application, software resource Software package for gene fusion discovery using RNA-Seq data. It uses clusters of discordant paired end alignments to inform a split read alignment analysis for finding fusion boundaries. rna sequencing, gene fusion, paired end alignment, split read, fusion boundary, bio.tools uses: SAMTOOLS
uses: Bowtie
uses: BLAT
uses: GMAP
uses: R Project for Statistical Computing
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
British Columbia Cancer Foundation ;
Vancouver General Hospital Foundation ;
Genome Canada ;
Michael Smith Foundation for Health Research ;
Canadian Breast Cancer Foundation ;
Canadian Institutes of Health Research's Bioinformatics Training Program
PMID:21625565 Free, Available for download, Freely available biotools:defuse, OMICS_01345 https://sourceforge.net/projects/defuse/
http://compbio.bccrc.ca/software/defuse/
https://bio.tools/defuse
http://sourceforge.net/apps/mediawiki/defuse/index.php?title=Main_Page SCR_003279 2026-02-14 02:00:44 95
PrimerSeq
 
Resource Report
Resource Website
1+ mentions
PrimerSeq (RRID:SCR_003295) PrimerSeq software resource Software that designs RT-PCR primers that evaluate alternative splicing events by incorporating RNA-Seq data. It is particularly advantageous for designing a large number of primers for validating alternative splicing events found in RNA-Seq data. It incorporates RNA-Seq data in the design process to weight exons by their read counts. Essentially, the RNA-Seq data allows primers to be placed using actually expressed transcripts. This could be for a particular cell line or experimental condition, rather than using annotations that incorporate transcripts that are not expressed for the data. Alternatively, you can design primers that are always on constitutive exons. PrimerSeq does not limit the use of gene annotations and can be used for a wide array of species. primer, rna-seq, rt-pcr, windows, mac os x, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24747190 Free, Available for download, Freely available biotools:primerseq, OMICS_02328 https://bio.tools/primerseq SCR_003295 Primer Seek in RNA-Seq 2026-02-14 02:00:25 7
MIPgen
 
Resource Report
Resource Website
10+ mentions
MIPgen (RRID:SCR_003325) software resource Software for a fast, simple way to generate designs for MIP assays targeting hundreds or thousands of genomic loci in parallel. Packaged with MIPgen are scripts that aid in visualization of MIP designs and processing of MIP sequence reads to SAM files that can then be passed through any standard variant calling pipeline. standalone software, c++, python, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Washington; Seattle; USA
PMID:24867941 Free, Available for download, Freely available OMICS_04657, biotools:mipgen https://github.com/shendurelab/MIPGEN
https://bio.tools/mipgen
SCR_003325 MIPgen - One stop MIP design and analysis 2026-02-14 02:00:46 48
Snakemake
 
Resource Report
Resource Website
100+ mentions
Snakemake (RRID:SCR_003475) Snakemake software resource A Python based language and execution environment for make-like workflows. The system supports the use of automatically inferred multiple named wildcards (or variables) in input and output filenames. python, workflow, bio.tools is used by: RiboSnake
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:22908215
DOI:10.1093/bioinformatics/bts480
Free, Available for download, Freely available OMICS_02299, biotools:snakemake https://snakemake.github.io/ SCR_003475 snakemake - A Python based language and execution environment for make-like workflows 2026-02-14 02:00:49 393
PheWAS R Package
 
Resource Report
Resource Website
1+ mentions
PheWAS R Package (RRID:SCR_003512) software resource Software package contains methods for performing Phenome-Wide Association Study. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Vanderbilt University; Tennessee; USA
PMID:20335276 Free OMICS_00242, biotools:phewas https://bio.tools/phewas SCR_003512 Phenome-Wide Association Study 2026-02-14 02:00:28 6
Cell Image Library (CIL)
 
Resource Report
Resource Website
10+ mentions
Cell Image Library (CIL) (RRID:SCR_003510) CIL data repository, storage service resource, data or information resource, service resource, image repository, database Freely accessible, public repository of vetted and annotated microscopic images, videos, and animations of cells from a variety of organisms, showcasing cell architecture, intracellular functionalities, and both normal and abnormal processes. Explore by Cell Process, Cell Component, Cell Type or Organism. The Cell includes images acquired from historical and modern collections, publications, and by recruitment. microscopic image repository, microscopic video repository, cell animation repository, bio.tools is used by: NIF Data Federation
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: Cell Centered Database
is related to: Cell Centered Database
is related to: OME-TIFF Format
is related to: Integrated Manually Extracted Annotation
has parent organization: American Society for Cell Biology
has parent organization: University of California; San Diego;National Center for Microscopy and Imaging Research - NCMIR
has parent organization: University of California at San Diego; California; USA
is parent organization of: Biological Imaging Methods Ontology
NIGMS RC2 GM092708 PMID:34218671
PMID:34218673
Free, Freely available biotools:cellimagelibrary, nif-0000-37639, r3d100011601 http://www.cellimagelibrary.org/pages/about
https://bio.tools/cellimagelibrary
https://doi.org/10.17616/R3N92J
SCR_003510 Cell Image Library. CIL, Cell Image Library (CIL) 2026-02-14 02:00:34 19
Bpipe
 
Resource Report
Resource Website
10+ mentions
Bpipe (RRID:SCR_003471) Bpipe software resource Software tool for running and managing bioinformatics pipelines. It specializes in enabling users to turn existing pipelines based on shell scripts or command line tools into highly flexible, adaptable and maintainable workflows with a minimum of effort. Bpipe ensures that pipelines execute in a controlled and repeatable fashion and keeps audit trails and logs to ensure that experimental results are reproducible. Requiring only Java as a dependency, it is fully self-contained and cross-platform, making it very easy to adopt and deploy into existing environments. genetics, dna, analysis, cluster, workflow, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:22500002 Free, Available for download, Freely available biotools:bpipe, OMICS_02301 https://github.com/ssadedin/bpipe SCR_003471 bpipe - A tool for running and managing bioinformatics pipelines 2026-02-14 02:00:49 13
Parseq
 
Resource Report
Resource Website
1+ mentions
Parseq (RRID:SCR_003464) Parseq software resource Statistical software for transcription landscape reconstruction at a basepair resolution from RNA Seq read counts. It is based on a state-space model which describes, in terms of abrupt shifts and more progressive drifts, the transcription level dynamics along the genome. Alongside variations of transcription level, it incorporates a component of short-range variation to pull apart local artifacts causing correlated dispersion. Reconstruction of the transcription level relies on a conditional sequential Monte Carlo approach that is combined with parameter estimation in a Markov chain Monte Carlo algorithm known as particle Gibbs. The method allows to estimate the local transcription level, to call transcribed regions, and to identify the transcript borders. rna-seq, genome, transcription, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Sorbonne University; Paris; France
PMID:24470570 Free, Available for download, Freely available biotools:parseq, OMICS_02302 https://bio.tools/parseq SCR_003464 2026-02-14 02:00:49 2
Proteomics Identifications (PRIDE)
 
Resource Report
Resource Website
500+ mentions
Proteomics Identifications (PRIDE) (RRID:SCR_003411) PRIDE data repository, storage service resource, data or information resource, service resource, database Centralized, standards compliant, public data repository for proteomics data, including protein and peptide identifications, post-translational modifications and supporting spectral evidence. Originally it was developed to provide a common data exchange format and repository to support proteomics literature publications. This remit has grown with PRIDE, with the hope that PRIDE will provide a reference set of tissue-based identifications for use by the community. The future development of PRIDE has become closely linked to HUPO PSI. PRIDE encourages and welcomes direct user submissions of protein and peptide identification data to be published in peer-reviewed publications. Users may Browse public datasets, use PRIDE BioMart for custom queries, or download the data directly from the FTP site. PRIDE has been developed through a collaboration of the EMBL-EBI, Ghent University in Belgium, and the University of Manchester. proteomics, protein, peptide, mass spectrometry, annotation, standard, spectra, protein-protein interaction, amino acid, amino acid sequence, post-translational modification, biomart, bio.tools is used by: ProteomeXchange
is used by: BioSample Database at EBI
is recommended by: NIDDK Information Network (dkNET)
is listed by: Biositemaps
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: HUPO Proteomics Standards Initiative
is related to: ProteomeXchange
has parent organization: European Bioinformatics Institute
Wellcome Trust WT085949MA;
European Union FP7 LSHG-CT-2006-036814;
European Union FP7 260558;
European Union FP7 262067;
European Union FP7 202272;
BBSRC BB/I024204/1
PMID:23203882
PMID:19662629
Free, Available for download, Freely available nif-0000-03336, biotools:pride, r3d100011515 https://www.ebi.ac.uk/pride/archive/
https://bio.tools/pride
https://doi.org/10.17616/R3F330
SCR_003411 PRoteomics IDEntifications database, PRIDE Archive - proteomics data repository, PRIDE Archive, PRIDE, Proteomics Identifications, Proteomics Identifications (PRIDE), PRoteomics IDEntifications database (PRIDE) 2026-02-14 02:00:48 642
MultiPhen
 
Resource Report
Resource Website
10+ mentions
MultiPhen (RRID:SCR_003498) software resource Software package that performs genetic association tests between SNPs (one-at-a-time) and multiple phenotypes (separately or in joint model). standalone software, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: CRAN
PMID:22567092 GNU General Public License, v2 biotools:multiphen, OMICS_04397 https://bio.tools/multiphen SCR_003498 MultiPhen: a package for the genetic association testing of multiple phenotypes 2026-02-14 02:00:34 29
EBSeq
 
Resource Report
Resource Website
500+ mentions
EBSeq (RRID:SCR_003526) EBSeq software resource Software R package for RNA-Seq Differential Expression Analysis. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
PMID:23428641
DOI:10.1093/bioinformatics/btt087
biotools:ebseq, OMICS_01307 https://bio.tools/ebseq
https://sources.debian.org/src/r-bioc-ebseq/
SCR_003526 2026-02-14 02:00:51 577
Reactome
 
Resource Report
Resource Website
1000+ mentions
Reactome (RRID:SCR_003485) data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Collection of pathways and pathway annotations. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes and small molecules) participating in reactions form a network of biological interactions and are grouped into pathways (signaling, innate and acquired immune function, transcriptional regulation, translation, apoptosis and classical intermediary metabolism) . Provides website to navigate pathway knowledge and a suite of data analysis tools to support the pathway-based analysis of complex experimental and computational data sets. pathway, interaction, reaction, nucleic acid, protein, complex, small molecule, signaling pathway, immune function, transcriptional regulation, translation, apoptosis, metabolism, ortholog, visualization, protein-protein interaction, web service, book, biomart, gold standard, bio.tools, FASEB list is used by: NIF Data Federation
is used by: DisGeNET
is used by: Pathway Analysis Tool for Integration and Knowledge Acquisition
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: WikiPathways
is related to: Pathway Commons
is related to: ConsensusPathDB
is related to: FlyMine
is related to: AmiGO
is related to: PSICQUIC Registry
is related to: Integrated Molecular Interaction Database
is related to: NCBI BioSystems Database
is related to: MOPED - Model Organism Protein Expression Database
is related to: KOBAS
is related to: PSICQUIC Registry
is related to: Pathway Interaction Database
is related to: hiPathDB - human integrated Pathway DB with facile visualization
is related to: Algal Functional Annotation Tool
has parent organization: Ontario Institute for Cancer Research
has parent organization: Cold Spring Harbor Laboratory
has parent organization: European Bioinformatics Institute
has parent organization: New York University School of Medicine; New York; USA
works with: PathwayMatcher
Ontario Research Fund ;
European Molecular Biology Laboratory ;
NHGRI P41 HG003751;
European Union FP6 ENFIN LSHG-CT-2005-518254;
NIGMS GM080223;
NIGMS R01 GM100039
PMID:21082427
PMID:21067998
Open source, Public, Freely available r3d100010285, nif-0000-03390, biotools:reactome https://bio.tools/reactome
https://doi.org/10.17616/R3V59P
SCR_003485 Reactome Functional Interaction Network 2026-02-14 02:00:50 4282
L-Measure
 
Resource Report
Resource Website
10+ mentions
L-Measure (RRID:SCR_003487) LM data processing software, service resource, software application, image processing software, software resource, image analysis software A freely available software tool available for the Windows and Linux platform, as well as the Online version Applet, for the analysis, comparison and search of digital reconstructions of neuronal morphologies. For the quantitative characterization of neuronal morphology, LM computes a large number of neuroanatomical parameters from 3D digital reconstruction files starting from and combining a set of core metrics. After more than six years of development and use in the neuroscience community, LM enables the execution of commonly adopted analyses as well as of more advanced functions, including: (i) extraction of basic morphological parameters, (ii) computation of frequency distributions, (iii) measurements from user-specified subregions of the neuronal arbors, (iv) statistical comparison between two groups of cells and (v) filtered selections and searches from collections of neurons based on any Boolean combination of the available morphometric measures. These functionalities are easily accessed and deployed through a user-friendly graphical interface and typically execute within few minutes on a set of 20 neurons. The tool is available for either online use on any Java-enabled browser and platform or may be downloaded for local execution under Windows and Linux. neuronal morphology, neuroinformatics, branching analysis, digital reconstruction, analysis, comparison, bio.tools is listed by: 3DVC
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
has parent organization: Computational Neuroanatomy Group
Human Brain Project ;
NINDS R01 NS39600
PMID:18451794 Public nif-0000-00003, biotools:l-measure http://www.nitrc.org/projects/lmeasure
https://bio.tools/l-measure
SCR_003487 2026-02-14 02:00:50 30
jmzTab
 
Resource Report
Resource Website
1+ mentions
jmzTab (RRID:SCR_003481) software resource A Java interface to the mzTab data exchange format for reporting a summary of proteomics results. standalone software, mac os x, unix/linux, java, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:24659499 Apache License, v2 OMICS_04542, biotools:jmztab https://bio.tools/jmztab SCR_003481 2026-02-14 02:00:50 1

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