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http://www.scienceexchange.com/facilities/najmanovich-research-group

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility provides consultancy services as well as contract work in all areas of bioinformatics, chemoinformatics and systems biology.

Proper citation: Universite de Sherbrooke Najmanovich Research Group Core Facility (RRID:SCR_012143) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/nuclear-magnetic-resonance-facility--2

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Nuclear Magnetic Resonance Facility (NMR) was established in 2004. The Facility recognizes the important role that NMR plays in molecular structure determination, drug design, protein and nucleic acid characterization, and conformational analysis. The instrumentation serves the high-resolution research needs for investigators from the Departments of Molecular and Cell Biology, Chemistry, and Pharmacy at the University of Connecticut.

Proper citation: UConn Nuclear Magnetic Resonance Facility (RRID:SCR_012347) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/biophysical-analysis-lab-purdue

The purpose of the Biophysical Analysis Lab (BAL) at the Bindley Biosciences Center is to provide complete biophysical analysis of macromolecules. In the lab, there are two analytical ultracentrifuges: Beckman-Coulter XLI and XLA, a Biacore 3000, an ITC, and a SEC-MALS platform. With these instruments we can determine kinetic parameters, stoichiometry of binding, size distribution, shape, oligomerization state and other biophysical measurements. Complementing these traditional biophysical methods, the BAL also provides mass spectrometric analyses at both the protein and peptide levels. The lab strives to establish long-term collaborations and deliver professional quality data that can be used for publications and grant proposals.

Proper citation: Purdue Biophysical Analysis Lab (RRID:SCR_012349) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/protein-x-ray-crystallography-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein X-ray Crystallography Facility became operational in October 2010 following the acquisition of a Rigaku HighFlux HomeLab system with funding awarded by the VPR''s Major Equipment Competition in November 2009.

Proper citation: UConn Protein X-Ray Crystallography Facility (RRID:SCR_012348) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/anti-infectives-screening-and-insectary-core-facilities-nyu

Our insectary produces five rodent malaria strains weekly and will ship live sporozoite infected Anopheles stephensi to investigators for research use (Plasmodium berghei GFP, luciferase or red-star and P. yoelii-GFP) Anti-infective testing including in vitro EC50, in vivo mice infection are available against for major parasitic diseases: Malaria, Leishmaniasis, Chagas and African Trypanosomiasis.

Proper citation: NYU Anti-Infectives Screening and Insectary Core Facilities (RRID:SCR_012350) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/proteomics/index.php

Provides LCMS/MS analysis of proteins in clinical, environmental and other biological samples. As a shared facility of the Bindley Bioscience Center (BBC) in Discovery Park of Purdue University, the facility enables both targeted and global analysis of proteins, their post-translational modifications and analysis of protein complexes and protein-protein interactions. Coupled with different chromatographic separation techniques, modern mass spectrometric instrumentation, and advanced scientific and bioinformatics expertise, the facility provides unique opportunities for researchers at Purdue and beyond to perform quantitative analysis of proteins in complex biological samples using both global, as well as, targeted proteomic approaches.

Proper citation: Purdue University Proteomics Core Facility (RRID:SCR_012351) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/pharmacology/index.php

Purdue Translational Pharmacology (PTP) facility provides in vivo pharmacological evaluation using porcine models. The facility is situated in the Purdue University School of Veterinary Medicine complex, which provides constant care and monitoring of the animals. The PTP uses unique penning systems to automate blood sampling and maintain a humane and stress free environment for test subjects. The PTP synergizes with the Metabolite Profiling Facility in the Bindley Bioscience Center, which facilitates the pharmacological analysis of blood samples collected.

Proper citation: Purdue Translational Pharmacology Core Facility (RRID:SCR_012354) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/flow-cytometry-cell-separation-facility-purdue

The Bindley Bioscience Flow Cytometry and Cell Separation Facility provides advanced cell and particle analysis and sorting using flow cytometry based technology. The facility also provides training in flow cytometry analysis and sorting techniques. The facility also provides expert consultation for assay and protocol development for flow cytometry analysis and cell separation.

Proper citation: Bindley Bioscience Flow Cytometry and Cell Separation Facility (RRID:SCR_012353) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/x-ray-crystallography-facility-purdue

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. The laboratory at Purdue is equipped with advanced instrumentation for small molecule crystallography. The main diffractometer is equipped with a micro-focus x-ray source to allow very small crystals (less than 0.1 mm) to be studied. Low temperature data collection is available to a temperature of 95K. The crystallographer has been at Purdue for over 26 years and is widely respected.

Proper citation: Purdue X-Ray Crystallography Facility (RRID:SCR_012356) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/bioscience/index.php

Provides instruments and expertise needed to visualize molecules in preparations ranging from single cells to entire animals. All facility users receive individualized instrument training as well as project specific advice for optimal data acquisition. Consultation on sample preparation, image rendering, and data analysis are also available as our knowledge base permits.

Proper citation: Purdue University Bioscience Imaging Core Facility (RRID:SCR_012355) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/centrillion-biosciences-inc

Centrillion offers a portfolio of genomic services to academic, clinical and industrial researchers. Core provides experimental design consultation, data production services, and bioinformatics analyses for a wide variety of genomic applications. Core offers access to next-gen sequencing, genotyping and bioinformatics analysis.

Proper citation: Centrillion Biosciences Inc. (RRID:SCR_012358) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/genomics-core

The mission of the Genomics Core is to provide state-of-the-art genomic services including genotyping and cell banking to investigators from UTHSCSA, CTRC and the local scientific community in an economical and timely manner.

Proper citation: UTHSCSA Genomics Core (RRID:SCR_012239) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/proteomics-core-rochester

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Offers state-of-the-art Mass Spectrometry and Biomarker Separation and Analysis Services.

Proper citation: URMC Proteomics Core (RRID:SCR_012361) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/x-ray-crystallography-core-laboratory

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15, 2024. The mission of the X-ray Crystallography Core Laboratory is to provide state-of-the-art resources to researchers at the University of Texas Health Science Center at San Antonio, and to external users, enabling the detailed 3-D analyses of biological macromolecules that play important roles in human health. This is a full service core in that it not only offers access to sophisticated equipment and technologies but also offers advice and technical assistance in sample preparation. Services are also provided to investigators without funding to facilitate the development of pilot data for new potentially fundable projects, as core resources permit. If priority of usage becomes an issue, this will be decided by the Core Director in consultation with the other principal scientists based on the feasibility of the projects, their scientific merits and their relevance to human health.

Proper citation: UTHSCSA X-ray Crystallography Core Laboratory (RRID:SCR_012242) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/microct-core-laboratory

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22, 2024. UTHSCSA Orthopaedics Bone and Mineral High-Resolution 3D Imaging Facility is a NIH-funded imaging facility equipped with two ex-vivo desktop microCT systems, a reference point indenter and a furnace. The non-destructive nature of microCT imaging allows the researcher to strengthen his/her research by using the same sample for histology or biomechanical testing after microCT imaging. Advantages of Micro-CT - Micro-CT allows for extremely high-resolution, non-destructive, 3D imaging. - No staining, sectioning, or sample preparation needed - Samples can be frozen or fixed - Since Micro-CT is non-destructive, other assays may be carried out after, thereby increasing the amount of data per sample - Data acquisition is a rapid process, allowing for a speedy return of samples

Proper citation: UTHSCSA MicroCT Core Laboratory (RRID:SCR_012241) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/confocal-and-conventional-microscopy-core-rochester

The Confocal and Conventional Microscopy Core provides Medical Center researchers access to high-end confocal microscopy as well as more conventional brightfield and fluorescence microscopy. The Core provides assistance with all imaging procedures as needed by the investigators. Aid in customizing staining protocols to optimize obtainment of high quality data using Core instruments is also provided. The CCMC provides Medical Center researchers the ability and expertise to obtain high quality imaging-based data from tissue, culture, and materials-based research studies. Core instrumentation includes a new Olympus FV1000 laser scanning confocal microscope, an accompanying workstation containing full Olympus FV1000 software, an Olympus VanoxAH-2 microscope for brightfield and fluorescence imaging, and an imaging stand for large specimen imaging. The core also offers a PalmBeam Laser Capture Microdissection Instrument for microdissection of tissue.

Proper citation: URMC Confocal and Conventional Microscopy Core (RRID:SCR_012365) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/diygenomics

DIYgenomics provides crowdsourced health research study protocol design and operation in pre-clinical and disease cohorts. Founded in 2010, the mission of DIYgenomics is the realization of preventive medicine through the integrated study of multiple health data streams. The generalized hypothesis for DIYgenomics studies is that one or more genetic polymorphisms (mutations) may result in out-of-bounds phenotypic biomarker conditions (for example, low Vitamin B blood levels), that may be ameliorated through personalized intervention.

Proper citation: DIYgenomics (RRID:SCR_012243) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/marvell-nanofabrication-laboratory, micro/nanoelectromechanical systems, microelectronics

The Marvell Nanofabrication Laboratory at the University of California, Berkeley is a multidisciplinary facility that serves research and education in the areas of integrated circuits (ICs) and systems, micro/nanofabrication technologies, micro/nanoelectromechanical (MEMS/NEMS) systems, advanced materials and interdisciplinary applications of microelectronics. This facility offers processing for both 4 inch and 6 inch substrates (wafers).

Proper citation: UC Berkeley Marvell Nanofabrication Laboratory (RRID:SCR_012246) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/gene-targeting-and-transgenic-core-rochester

Currently, the Gene Targeting and Transgenic Core''s services include the production of mouse models using DNA microinjection and embryonic stem cell injection (from gene targeting in mouse ES cells to production of chimeric mice) methodologies. Additional services have included: various analytical techniques, embryo cryopreservation, rederivation of pathogen-free rodents, and assisted reproduction techniques (e.g., in vitro fertilization (IVF), superovulation, and embryo transfer). Specific strains, and alternative species and methods are considered when appropriate for individual research applications.

Proper citation: URMC Gene Targeting and Transgenic Core (RRID:SCR_012367) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/metabolomics-core-laboratory-mass-spectrometry-uthscsa

Cutting-edge mass spectrometers deliver extremely high mass accuracy and resolution to elucidate the identity and quantity of small molecules. Metabolomics Laboratory Services: Qualitative and quantitative analysis of small molecules - Molecular mass determination - Structural elucidation - Quantification Targeted and discovery modes of analysis - Quantitative analysis of targeted metabolites - Metabolite profiling for differential comparisons between experimental groups - High-throughput sample analysis The Metabolomics Laboratory is supported by awards from the National Institutes of Health, including a Shared Instrumentation grant (1S10RR031586-01) and a supplement to the Clinical and Translational Sciences Award (3UL1RR025767-03S1).

Proper citation: UTHSCSA Metabolomics Core Laboratory Mass Spectrometry (RRID:SCR_012245) Copy   

•   Source: SciCrunch Registry