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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
FARMS
 
Resource Report
Resource Website
10+ mentions
FARMS (RRID:SCR_001344) FARMS software resource Software using a model-based technique for summarizing high-density oligonucleotide array data at probe level for Affymetrix GeneChips. It is based on a factor analysis model for which a Bayesian maximum a posteriori method optimizes the model parameters under the assumption of Gaussian measurement noise. oligonucleotide array, probe, affymetrix genechip, r, unix, windows, microarray, summarization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Johannes Kepler University of Linz; Linz; Austria
PMID:16473874 Free, Freely Available OMICS_01995, biotools:farms https://bio.tools/farms SCR_001344 Factor Analysis for Robust Microarray Summarization 2026-02-14 01:59:59 28
bridge
 
Resource Report
Resource Website
100+ mentions
bridge (RRID:SCR_001343) bridge software resource Software package to test for differentially expressed genes with microarray data. It can be used with both cDNA microarrays or Affymetrix chip. The packge fits a robust Bayesian hierarchical model for testing for differential expression. Outliers are modeled explicitly using a $t$-distribution. The model includes an exchangeable prior for the variances which allow different variances for the genes but still shrink extreme empirical variances. The model can be used for testing for differentially expressed genes among multiple samples, and can distinguish between the different possible patterns of differential expression when there are three or more samples. Parameter estimation is carried out using a novel version of Markov Chain Monte Carlo that is appropriate when the model puts mass on subspaces of the full parameter space. cdna microarray, affymetrix chip, differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:16542223 Free, Available for download, Freely available OMICS_01996, biotools:bridge http://www.bioconductor.org/packages/release/bioc/html/bridge.html SCR_001343 Bayesian Robust Inference for Differential Gene Expression 2026-02-14 02:00:01 156
aroma.light
 
Resource Report
Resource Website
1+ mentions
aroma.light (RRID:SCR_001312) aroma.light software resource Light-weight software package for normalization and visualization of microarray data using only basic R data types. Software can be used standalone, be utilized in other packages, or be wrapped up in higher-level classes. infrastructure, microarray, preprocessing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
DOI:10.1186/1471-2105-11-245 Free, Available for download, Freely available OMICS_01998, biotools:aroma.light https://bio.tools/aroma.light
https://sources.debian.org/src/r-bioc-aroma.light/
SCR_001312 2026-02-14 02:00:00 1
BeadDataPackR
 
Resource Report
Resource Website
BeadDataPackR (RRID:SCR_001310) BeadDataPackR software resource Software that provides functionality for the compression and decompression of raw bead-level data from the Illumina BeadArray platform. microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:20981138 Free, Available for download, Freely available biotools:beaddatapackr, OMICS_02023 https://bio.tools/beaddatapackr SCR_001310 BeadDataPackR - Compression of Illumina BeadArray data 2026-02-14 02:00:05 0
OLIN
 
Resource Report
Resource Website
10+ mentions
OLIN (RRID:SCR_001304) OLIN software resource Software functions for normalization of two-color microarrays by optimised local regression and for detection of artifacts in microarray data. r, normalization, visualization, quality control, two-channel, microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Humboldt University of Berlin; Berlin; Germany
has parent organization: Bioconductor
PMID:15585527 Free, Available for download, Freely available biotools:olin, OMICS_02029 http://itb.biologie.hu-berlin.de/~futschik/software/R/OLIN/index.html SCR_001304 Optimised Local Intensity-dependent Normalisation 2026-02-14 01:59:58 18
qcmetrics
 
Resource Report
Resource Website
1+ mentions
qcmetrics (RRID:SCR_001303) qcmetrics software resource Software package that provides a framework for generic quality control of data. It permits to create, manage and visualise individual or sets of quality control metrics and generate quality control reports in various formats. mass spectrometry, microarray, proteomics, quality control, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02032, biotools:qcmetrics, BioTools:qcmetrics https://bio.tools/qcmetrics
https://bio.tools/qcmetrics
https://bio.tools/qcmetrics
SCR_001303 qcmetrics - A Framework for Quality Control 2026-02-14 02:00:00 1
DEXUS
 
Resource Report
Resource Website
1+ mentions
DEXUS (RRID:SCR_001309) DEXUS software resource Software package that identifies differentially expressed genes in RNA-Seq data under all possible study designs such as studies without replicates, without sample groups, and with unknown conditions. It works also for known conditions, for example for RNA-Seq data with two or multiple conditions. RNA-Seq read count data can be provided both by the S4 class Count Data Set and by read count matrices. Differentially expressed transcripts can be visualized by heatmaps, in which unknown conditions, replicates, and samples groups are also indicated. This software is fast since the core algorithm is written in C. For very large data sets, a parallel version of DEXUS is provided in this package. DEXUS is a statistical model that is selected in a Bayesian framework by an EM algorithm. It does not need replicates to detect differentially expressed transcripts, since the replicates (or conditions) are estimated by the EM method for each transcript. The method provides an informative/non-informative value to extract differentially expressed transcripts at a desired significance level or power. classification, differential expression, gene expression, hapmap, quality control, rna-seq, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24049071 Free, Available for download, Freely available biotools:dexus, OMICS_02024 http://www.bioconductor.org/packages/release/bioc/html/dexus.html SCR_001309 DEXUS - Identifying Differential Expression in RNA-Seq Studies with Unknown Conditions or without Replicates 2026-02-14 02:00:00 1
ADaCGH2
 
Resource Report
Resource Website
ADaCGH2 (RRID:SCR_001981) software resource Software for analysis and plotting of array comparative genomic hybridization (CGH) data. It allows usage of Circular Binary Segementation, wavelet-based smoothing (both as in Liu et al., and HaarSeg as in Ben-Yaacov and Eldar), HMM, BioHMM, GLAD, CGHseg. Most computations are parallelized (either via forking or with clusters, including MPI and sockets clusters) and use ff for storing data. standalone software, mac os x, unix/linux, windows, r, copy number variant, microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24532724 Free, Available for download, Freely available biotools:adacgh2, OMICS_03697 https://bio.tools/adacgh2 SCR_001981 ADaCGH2 - Analysis of big data from aCGH experiments using parallel computing and ff objects 2026-02-14 02:00:12 0
PurBayes
 
Resource Report
Resource Website
10+ mentions
PurBayes (RRID:SCR_002068) software resource An MCMC-based algorithm that uses next-generation sequencing data to estimate tumor purity and clonality for paired tumor-normal data. software package, unix/linux, mac os x, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: CRAN
PMID:23749958 Free, Available for download, Freely available biotools:purbayes, OMICS_03561 https://bio.tools/purbayes http://cran.r-project.org/web/packages/PurBayes/ SCR_002068 PurBayes: Bayesian Estimation of Tumor Purity and Clonality 2026-02-14 02:00:18 10
BEETL-fastq
 
Resource Report
Resource Website
BEETL-fastq (RRID:SCR_002341) software resource Software tool that not only compresses FASTQ-formatted DNA reads more compactly than gzip but also permits rapid search for k-mer queries within the archived sequences. The full FASTQ record of each matching read or read pair is returned, allowing the search results to be piped directly to any of the many standard tools that accept FASTQ data as input. Searchable compressed archive for DNA reads. Searchable compressed archive, DNA reads, compresses FASTQ-formatted DNA reads, bio.tools, is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Burrows-Wheeler transform
PMID:24950811 Free, Available for download, Freely available OMICS_04900, biotools:beetl https://bio.tools/beetl SCR_002341 2026-02-14 02:00:16 0
CisGenome
 
Resource Report
Resource Website
50+ mentions
CisGenome (RRID:SCR_001558) data analysis tool Integrated software tool for tiling array, ChIP-seq, genome and cis-regulatory element analysis. sequencing software, chip seq, downstream analysis, chip analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
works with: TileMap
PMID:18978777 Free, Available for download, Freely available OMICS_00423, biotools:cisgenome https://bio.tools/cisgenome http://biogibbs.stanford.edu/~jihk/CisGenome/index.htm SCR_001558 CisGenome v2.0 2026-02-14 02:00:06 82
vsn
 
Resource Report
Resource Website
1+ mentions
vsn (RRID:SCR_001459) vsn software resource Software package that implements a method for normalizing microarray intensities, both between colours within array, and between arrays. The method uses a robust variant of the maximum-likelihood estimator for the stochastic model of microarray data described in the references. The model incorporates data calibration (a.k.a. normalization), a model for the dependence of the variance on the mean intensity, and a variance stabilizing data transformation. Differences between transformed intensities are analogous to normalized log-ratios. However, in contrast to the latter, their variance is independent of the mean, and they are usually more sensitive and specific in detecting differential transcription. microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
Free, Available for download, Freely available OMICS_01977, biotools:vsn https://bio.tools/vsn SCR_001459 vsn - Variance stabilization and calibration for microarray data 2026-02-14 02:00:09 5
InterMine
 
Resource Report
Resource Website
10+ mentions
InterMine (RRID:SCR_001772) software resource An open source data warehouse system built for the integration and analysis of complex biological data that enables the creation of biological databases accessed by sophisticated web query tools. Parsers are provided for integrating data from many common biological data sources and formats, and there is a framework for adding data. InterMine includes a user-friendly web interface that works "out of the box" and can be easily customized for specific needs, as well as a powerful, scriptable web-service API to allow programmatic access to data. mac os x, unix/linux, windows, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Cambridge; Cambridge; United Kingdom
Wellcome Trust PMID:24753429 Free, Freely available OMICS_03840, biotools:intermine https://github.com/intermine/intermine
https://bio.tools/intermine
http://intermine.github.io/intermine.org/ SCR_001772 2026-02-14 02:00:07 22
unifiedWMWqPCR
 
Resource Report
Resource Website
unifiedWMWqPCR (RRID:SCR_001706) software resource Software package that implements the unified Wilcoxon-Mann-Whitney Test for qPCR data. This modified test allows for testing differential expression in qPCR data. standalone software, mac os x, unix/linux, windows, r, gene expression, microtitre plate assay, qpcr, differential expression, multiple comparison, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24794933 Free, Available for download, Freely available OMICS_03937, biotools:unifiedwmwqpcr https://bio.tools/unifiedwmwqpcr SCR_001706 unifiedWMWqPCR - Unified Wilcoxon-Mann Whitney Test for testing differential expression in qPCR data 2026-02-14 02:00:16 0
CCAT
 
Resource Report
Resource Website
50+ mentions
CCAT (RRID:SCR_001843) CCAT software resource THIS RESOURCE IS OUT OF SERVICE, documented on April 5, 2017, A software package for the analysis of ChIP-seq data with negative control., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Genome Institute of Singapore; Singapore; Singapore
PMID:20371496 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00428, biotools:ccat https://bio.tools/ccat SCR_001843 Control based ChIP-Seq Analysis Tools 2026-02-14 02:00:09 76
S-MART
 
Resource Report
Resource Website
10+ mentions
S-MART (RRID:SCR_001908) S-MART software resource Software toolbox that manages your RNA-Seq and ChIP-Seq data and also produces many different plots to visualize your data. It performs several tasks that are usually required during the analysis of mapped RNA-Seq and ChIP-Seq reads, including data selection and data visualization. It includes the selection (or the exclusion) of the data that overlaps with a reference set, clustering and comparative analysis. It also provides many ways to visualize data: size of the reads, density on the genome, distance with respect to a reference set, and the correlation of two data sets (with cloud plots). A computer science background is not required to run it through a graphical interface and it can be run on any personal computer, yielding results within an hour for most queries. high throughput sequencing, rna-seq, chip-seq, python, linux, ms windows, mac, short-read, selection, visualization, bio.tools, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:21998740 Free, Available for download, Freely available OMICS_01937, biotools:mapperanalyzer, biotools:s-mart https://bio.tools/s-mart
https://bio.tools/mapperanalyzer
SCR_001908 2026-02-14 02:00:11 23
SamSPECTRAL
 
Resource Report
Resource Website
1+ mentions
SamSPECTRAL (RRID:SCR_001858) software resource Software that identifies cell population in flow cytometry data. It demonstrates significant advantages in proper identification of populations with non-elliptical shapes, low density populations close to dense ones, minor subpopulations of a major population and rare populations. It samples large data such that spectral clustering is possible while preserving density information in edge weights. More specifically, given a matrix of coordinates as input, SamSPECTRAL first builds the communities to sample the data points. Then, it builds a graph and after weighting the edges by conductance computation, the graph is passed to a classic spectral clustering algorithm to find the spectral clusters. The last stage of SamSPECTRAL is to combine the spectral clusters. The resulting connected components estimate biological cell populations in the data sample. software package, mac os x, unix/linux, windows, r, cell biology, clustering, flow cytometry, stem cell, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
Cancer, HIV PMID:20667133 Free, Available for download, Freely available OMICS_05638, biotools:samspectral https://bio.tools/samspectral SCR_001858 SamSPECTRAL - Identifies cell population in flow cytometry data 2026-02-14 02:00:13 4
CQN
 
Resource Report
Resource Website
1+ mentions
CQN (RRID:SCR_001786) CQN software resource A normalization tool for RNA-Seq data, implementing the conditional quantile normalization method. rna-seq, differential expression, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:22285995 Free, Available for download, Freely available OMICS_01949, biotools:cqn https://bio.tools/cqn SCR_001786 Conditional Quantile Normalization 2026-02-14 02:00:11 6
pFind Studio: pLink
 
Resource Report
Resource Website
10+ mentions
pFind Studio: pLink (RRID:SCR_000084) pLink software resource Software dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. mass spectrometry, proteomics, pFind Studio, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chinese Academy of Sciences; Beijing; China
PMID:22772728 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02404, biotools:pLink-2 https://github.com/pFindStudio/pLink3/releases http://pfind.ict.ac.cn/software/pLink/index.html SCR_000084 , pLink, pLink (pFind Studio), pLink2 2026-02-14 01:59:37 15
DNAcopy
 
Resource Report
Resource Website
100+ mentions
DNAcopy (RRID:SCR_012560) DNAcopy software resource Software that segments DNA copy number data using circular binary segmentation to detect regions with abnormal copy number. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
OMICS_00720, biotools:dnacopy https://bio.tools/dnacopy
https://sources.debian.org/src/r-bioc-dnacopy/
SCR_012560 2026-02-14 02:02:42 334

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