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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
BEAST
 
Resource Report
Resource Website
5000+ mentions
BEAST (RRID:SCR_010228) sequence analysis software, data processing software, software repository, data analysis software, software application, software resource A cross-platform software program for Bayesian MCMC analysis of molecular sequences. It is entirely orientated towards rooted, time-measured phylogenies inferred using strict or relaxed molecular clock models. It can be used as a method of reconstructing phylogenies but is also a framework for testing evolutionary hypotheses without conditioning on a single tree topology. BEAST uses MCMC to average over tree space, so that each tree is weighted proportional to its posterior probability. We include a simple to use user-interface program for setting up standard analyses and a suit of programs for analysing the results. bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: TempEst
is related to: BEAST2
is related to: PhyDyn
has parent organization: University of Edinburgh; Scotland; United Kingdom
DOI:10.1186/1471-2148-7-214 nlx_156859, OMICS_04233, biotools:beast, SCR_015988 http://www.nitrc.org/projects/beast-library
https://bio.tools/beast
https://sources.debian.org/src/beast-mcmc/
http://beast.bio.ed.ac.uk/Main_Page SCR_010228 BEaST Segmentation Library, Beast Software 2026-02-14 02:01:55 6460
WEBLOGO
 
Resource Report
Resource Website
1000+ mentions
WEBLOGO (RRID:SCR_010236) data access protocol, software resource, web service, service resource Web application to generate sequence logos, graphical representations of patterns within multiple sequence alignment. Designed to make generation of sequence logos easy. Sequence logo generator. Generate sequence logo, pattern graphical representation, multiple sequence alignment, sequence logo generator, amino acid sequence alignment, nucleic acid sequence alignment, sequence alignment representation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of California at Berkeley; Berkeley; USA
NHGRI K22 HG00056;
Searle Scholars program ;
NIGMS P50 GM62412
PMID:15173120 Free, Available for download, Freely available nlx_156853, biotools:weblogo_3 http://weblogo.threeplusone.com/
https://bio.tools/weblogo_3
SCR_010236 WebLogo Version 2.8.2, WebLogo3, WebLogo 2026-02-14 02:01:55 3653
MaSuRCA
 
Resource Report
Resource Website
100+ mentions
MaSuRCA (RRID:SCR_010691) MaSuRCA software resource A whole genome assembly software that combines the efficiency of the de Bruijn graph and Overlap-Layout-Consensus (OLC) approaches., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Maryland; Maryland; USA
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00020, biotools:masurca https://bio.tools/masurca SCR_010691 2026-02-14 02:02:02 463
Pathema
 
Resource Report
Resource Website
1+ mentions
Pathema (RRID:SCR_010585) Pathema data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Pathema is one of the eight Bioinformatics Resource Centers designed to serve as a core resource for the bio-defense and infectious disease research community. Pathema strives to support basic research and accelerate scientific progress for understanding, detecting, diagnosing and treating an established set of six target NIAID Category A-C pathogens: Category A priority pathogens; Bacillus anthracis and Clostridium botulinum, and Category B priority pathogens; Burkholderia mallei, Burkholderia pseudomallei, Clostridium perfringens and Entamoeba histolytica. Each target pathogen is represented in one of four distinct clade-specific Pathema web resources and underlying databases developed to target the specific data and analysis needs of each scientific community. All publicly available complete genome projects of phylogenetically related organisms are also represented, providing a comprehensive collection of organisms for comparative analyses. Pathema facilitates the scientific exploration of genomic and related data through its integration with web-based analysis tools, customized to obtain, display, and compute results relevant to ongoing pathogen research. Pathema serves the bio-defense and infectious disease research community by disseminating data resulting from pathogen genome sequencing projects and providing access to the results of inter-genomic comparisons for these organisms. The Pathema BRC contract ends in December 2009. At that time JCVI will cease maintenance of the Pathema web resource and data. The PATRIC team, located at the Virginia Bioinformatics Institute, created and maintains a consolidated BRC for all of the NIAID category A-C priority pathogenic bacteria. The EuPathDB team at the University of Pennsylvania will support all eukaryotic pathogens. Pathema transferred all data and software to PATRIC and EuPathDB for incorporation into their new Web-based bioinformatics resource. bacillus anthracis, clostridium botulinum, burkholderia mallei, burkholderia pseudomallei, clostridium perfringens, entamoeba histolytica, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: J. Craig Venter Institute
NIAID contract HHSN266200400038C PMID:19843611 biotools:pathema, nlx_45829 https://bio.tools/pathema SCR_010585 Pathema Genome Resource, Pathema Bioinformatics Resource Center 2026-02-14 02:02:02 6
GenoTan
 
Resource Report
Resource Website
1+ mentions
GenoTan (RRID:SCR_007935) GenoTan software resource A free software tool to identify length variation of microsatellites from short sequence reads. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24135263 GNU General Public License, v3 biotools:genotan https://bio.tools/genotan SCR_007935 GenoTan - Genotyping of microsatellite loci 2026-02-14 02:01:27 1
VISTA Enhancer Browser
 
Resource Report
Resource Website
100+ mentions
VISTA Enhancer Browser (RRID:SCR_007973) VISTA Enhancer Browser data repository, storage service resource, data or information resource, service resource, database Resource for experimentally validated human and mouse noncoding fragments with gene enhancer activity as assessed in transgenic mice. Most of these noncoding elements were selected for testing based on their extreme conservation in other vertebrates or epigenomic evidence (ChIP-Seq) of putative enhancer marks. Central public database of experimentally validated human and mouse noncoding fragments with gene enhancer activity as assessed in transgenic mice. Users can retrieve elements near single genes of interest, search for enhancers that target reporter gene expression to particular tissue, or download entire collections of enhancers with defined tissue specificity or conservation depth. human, noncoding fragment, mutant mouse strain, molecular neuroanatomy resource, image, telencephalon, development, genome, enhancer, dna fragment, embryo, embryonic mouse, brain, neural tube, eye, ear, heart, tail, limb, nose, cranial nerve, trigeminal, dorsal root ganglia, face, branchial arch, gene expression, annotation, vector, transgenic embryo, lacz reporter vector, lacz, biomaterial supply resource, in vivo, image collection, transcriptional enhancer, chip-seq, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: NIF Data Federation
is related to: One Mind Biospecimen Bank Listing
is related to: OMICtools
has parent organization: Lawrence Berkeley National Laboratory
American Heart Association ;
NIDCR ;
NHLBI HL066681;
NHGRI HG003988;
DOE contract DE-AC02-05CH11231;
NINDS NS062859;
DOE DE020060
PMID:17130149 Free, Freely available nif-0000-03637, OMICS_01568, biotools:vista_enhancer_browser https://bio.tools/vista_enhancer_browser SCR_007973 2026-02-14 02:01:36 233
T1DBase
 
Resource Report
Resource Website
100+ mentions
T1DBase (RRID:SCR_007959) data repository, storage service resource, resource, data or information resource, service resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 26,2019. In October 2016, T1DBase has merged with its sister site ImmunoBase (https://immunobase.org). Documented on March 2020, ImmunoBase ownership has been transferred to Open Targets (https://www.opentargets.org). Results for all studies can be explored using Open Targets Genetics (https://genetics.opentargets.org). Database focused on genetics and genomics of type 1 diabetes susceptibility providing a curated and integrated set of datasets and tools, across multiple species, to support and promote research in this area. The current data scope includes annotated genomic sequences for suspected T1D susceptibility regions; genetic data; microarray data; and global datasets, generally from the literature, that are useful for genetics and systems biology studies. The site also includes software tools for analyzing the data. genetics, beta cell, gene, variant, region, genomics, gene expression, genome-wide association study, data analysis service, bio.tools is used by: NIF Data Federation
is used by: NIDDK Information Network (dkNET)
is listed by: NIDDK Information Network (dkNET)
is listed by: Debian
is listed by: bio.tools
is related to: dkCOIN
has parent organization: University of Cambridge; Cambridge; United Kingdom
Type 1 diabetes. Diabetes Wellcome Trust ;
NIDDK ;
Juvenile Diabetes Research Foundation
PMID:20937630 THIS RESOURCE IS NO LONGER IN SERVICE. nif-0000-03531, biotools:t1dbase https://bio.tools/t1dbase SCR_007959 T1DBase - Type 1 Diabetes Database 2026-02-14 02:01:34 145
HilbertVis
 
Resource Report
Resource Website
1+ mentions
HilbertVis (RRID:SCR_007862) HilbertVis software resource Software tool that allows to display very long data vectors in a space-efficient manner, allowing the user to visually judge the large scale structure and distribution of features simultaneously with the rough shape and intensity of individual features. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: European Bioinformatics Institute
DOI:10.1093/bioinformatics/btp152 OMICS_00627, biotools:hilbertvis https://bio.tools/hilbertvis
https://sources.debian.org/src/r-bioc-hilbertvis/
SCR_007862 2026-02-14 02:01:35 4
BRIG
 
Resource Report
Resource Website
100+ mentions
BRIG (RRID:SCR_007802) BRIG software resource A cross-platform (Windows/Mac/Unix) application that can display circular comparisons between a large number of genomes, with a focus on handling genome assembly data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
DOI:10.1186/1471-2164-12-402 OMICS_00929, biotools:brig https://bio.tools/brig
https://sources.debian.org/src/brig/
SCR_007802 BLAST Ring Image Generator 2026-02-14 02:01:26 497
dbEST
 
Resource Report
Resource Website
100+ mentions
dbEST (RRID:SCR_008132) data repository, storage service resource, data or information resource, service resource, database Database as a division of GenBank that contains sequence data and other information on single-pass cDNA sequences, or Expressed Sequence Tags, from a number of organisms. data, sequence, single, pass, cDNA, express, tag, bio.tools, gold standard is listed by: Debian
is listed by: bio.tools
has parent organization: NCBI
PMID:8401577 biotools:dbest, nif-0000-20937, r3d100010648 http://www.ncbi.nlm.nih.gov/dbEST/
https://bio.tools/dbest
https://doi.org/10.17616/R3FG8P
SCR_008132 database Expressed Sequence Tag (EST), database Expressed Sequence Tag 2026-02-14 02:01:38 179
lobSTR
 
Resource Report
Resource Website
10+ mentions
lobSTR (RRID:SCR_008030) lobSTR software resource A software tool for profiling Short Tandem Repeats (STRs) from high throughput sequencing data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
PMID:22522390 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00109, biotools:lobstr https://bio.tools/lobstr SCR_008030 lobSTR - Profiling STRs in personal genomes 2026-02-14 02:01:37 47
ActiveDriver
 
Resource Report
Resource Website
10+ mentions
ActiveDriver (RRID:SCR_008104) ActiveDriver sequence analysis software, data processing software, data analysis software, software application, software resource A statistical method for interpreting variations in protein sequence (e.g. coding SNPs in the population, SNVs in cancer genomes) in the context of protein post-translational signaling modifications. Protein sequence variation, variation interpretation, protein sequence, protein post-translational signaling modifications, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:ActiveDriver, OMICS_00140 http://reimandlab.org/software/activedriver/
https://cran.r-project.org/web/packages/ActiveDriver/ActiveDriver.pdf
https://bio.tools/ActiveDriver
SCR_008104 2026-02-14 02:01:38 25
QIIME
 
Resource Report
Resource Website
10000+ mentions
QIIME (RRID:SCR_008249) data analysis software, software resource, data processing software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 23,2023.Software package for comparison and analysis of microbial communities, primarily based on high-throughput amplicon sequencing data, but also supporting analysis of other types of data. QIMME analyzes and transforms raw sequencing data generated on Illumina or other platforms to publication quality graphics and statistics. microbiome, microbial community, sequence data, data analysis software, bio.tools is used by: SortMeRNA
is used by: Nephele
is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Colorado Boulder; Colorado; USA
DOI:10.1038/nmeth.f.303 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01118, SCR_011948, OMICS_01521, biotools:qiime https://bio.tools/qiime SCR_008249 Quantitative Insights Into Microbial Ecology 2026-02-14 02:01:38 11036
IsaCGH
 
Resource Report
Resource Website
IsaCGH (RRID:SCR_008375) IsaCGH software resource Software to analyze CNV that will now normalize arrays CGH and it will visually integrate different genome annotations. microarray, array cgh, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
OMICS_00727, biotools:isacgh https://bio.tools/isacgh SCR_008375 2026-02-14 02:01:41 0
G protein receptor interaction feature finding instrument
 
Resource Report
Resource Website
10+ mentions
G protein receptor interaction feature finding instrument (RRID:SCR_008343) production service resource, service resource, analysis service resource, resource Griffin (G-protein-receptor interacting feature finding instrument) is a high-throughput system to predict GPCR - G-protein coupling selectively with the input of GPCR sequence and ligand molecular weight. This system consists of two parts: 1) HMM section using family specific multiple alignment of GPCRs, 2) SVM section using physico-chemical feature vectors in GPCR sequence. G-protein coupled receptors (GPCR), which is composed of seven transmembrane helices, play a role as interface of signal transduction. The external stimulation for GPCR, induce the coupling with G-protein (Gi/o, Gq/11, Gs, G12/13) followed by different kinds of signal transduction to inner cell. About half of distributed drugs are intending to control this GPCR - G-protein binding system, and therefore this system is important research target for the development of effective drug. For this purpose, it is necessary to monitor, effectively and comprehensively, of the activation of G-protein by identifying ligand combined with GPCR. Since, at present, it is difficult to construct such biochemical experiment system, if the answers for experimental results can be prepared beforehand by using bioinformatics techniques, large progress is brought to G-protein related drug design. Previous works for predicting GPCR-G protein coupling selectivity are using sequence pattern search, statistical models, and HMM representations showed high sensitivity of predictions. However, there are still no works that can predict with both high sensitivity and specificity. In this work we extracted comprehensively the physico-chemical parameters of each part of ligand, GPCR and G-protein, and choose the parameters which have strong correlation with the coupling selectivity of G-protein. These parameters were put as a feature vector, used for GPCR classification based on SVM. drug, alignment, biochemical, bioinformatic, coupling, gpcr, g-protein, helix, instrument, interface, ligand, molecular, pattern, physico-chemical, receptor interacting, sequence, signal transduction, stimulation, svm, system, technique, transmembrane, weight, instrument, equipment, hardware, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Computational Biology Research Center Core Facility
National Institute of Advanced Industrial Science and Technology nif-0000-25210, biotools:griffin https://bio.tools/griffin SCR_008343 Griffin 2026-02-14 02:01:37 19
CAT
 
Resource Report
Resource Website
10+ mentions
CAT (RRID:SCR_008421) CAT software resource A repository of tools for analysis and annotation of CAZYmes (Carbohydrate Active enZYmes)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01676, biotools:CAt https://bio.tools/CAT SCR_008421 2026-02-14 02:01:38 13
COPASI
 
Resource Report
Resource Website
100+ mentions
COPASI (RRID:SCR_014260) COPASI data processing software, data analysis software, software application, software resource, simulation software, standalone software Software application for simulation and analysis of biochemical network models and their dynamics. COPASI supports models in the SBML standard and can simulate their behavior using ODEs or Gillespies stochastic simulation algorithm. Arbitrary discrete events can be included in such simulations. Models in COPASI are based on reactions that convert a set of species into another set of species. Simulation can be performed either with stochastic kinetics or with differential equations. COPASI also includes various methods of analysis and data visualization. standalone software, simulation software, data analysis, biochemical system simulator, biochemical network model, biochemical network dynamics, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1093/bioinformatics/btl485 Free, Available for download, Acknowledgement requested biotools:copasi https://bio.tools/copasi SCR_014260 COPASI: Biochemical System Simulator 2026-02-14 02:02:36 435
CYANA
 
Resource Report
Resource Website
100+ mentions
CYANA (RRID:SCR_014229) data analysis software, software resource, data processing software, software application Software for automated structure calculation of biological macromolecules on basis of conformational constraints from nuclear magnetic resonance. Program for automated NMR protein structure calculation. CYANA requires a sufficient list of assigned chemical shifts and lists of cross-peak positions and columns from 2D, 3D, or4D NOESY spectra in order to calculate the assignment of the NOESY cross-peaks and the 3D structure of the protein in solution. protein structure, nmr, noesy, 3d structure, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Goethe University Frankfurt am Main; Hessen; Germany
has parent organization: RIKEN
PMID:15318003
PMID:25801209
Available to the academic community, Available to commercial user, Pay for license SCR_021949, biotools:cyana http://www.las.jp/english/products/cyana.html
https://bio.tools/cyana
https://dbpedia.org/page/CYANA_(software)
SCR_014229 2026-02-14 02:02:57 425
Coot
 
Resource Report
Resource Website
10000+ mentions
Coot (RRID:SCR_014222) COOT data or information resource, model, software toolkit, software application, software resource, simulation software Software for macromolecular model building, model completion and validation, and protein modelling using X-ray data. Coot displays maps and models and allows model manipulations such as idealization, rigid-body fitting, ligand search, Ramachandran plots, non-crystallographic symmetry and more. Source code is available. software toolkit, simulation software, model manipulation, protein modeling, bio.tools is used by: PDB-REDO
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: MolProbity
has parent organization: MRC Laboratory of Molecular Biology
PMID:15572765 Available for download, Acknowledgement requested biotools:coot http://strucbio.biologie.uni-konstanz.de/ccp4wiki/index.php/Coot
https://bio.tools/coot
SCR_014222 Crystallographic Object-Oriented Toolkit 2026-02-14 02:02:35 14789
SHELX
 
Resource Report
Resource Website
500+ mentions
SHELX (RRID:SCR_014220) data processing software, software application, software resource, image reconstruction software, image analysis software, standalone software A set of software programs that utilizes dual spaces algorithms for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction. Libraries, extra files and environment variables are not required for the executables. SHELX is intended to be run on a command prompt but may be called from GUIs such as shelXle, Olex2, Oscail or WinGX, or hkl2map., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, image reconstruction software, image analysis software, crystal structure, crystal xray, neutron diffraction, bio.tools is listed by: bio.tools
is listed by: Debian
DOI:10.1107/S2053273314026370 THIS RESOURCE IS NO LONGER IN SERVICE biotools:shelx https://bio.tools/shelx SCR_014220 2026-02-14 02:02:38 520

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