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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_4535
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study TNF-mediated cytotoxicity in microgravity (PubMed=8125155)., Group: Space-flown cell line (cellonaut)., Group: Serum/protein free medium cell line.
Proper citation: BCRC Cat# 60405, RRID:CVCL_4535 Copy
https://web.expasy.org/cellosaurus/CVCL_0382
Organism: Mus musculus (Mouse)
Disease: Mouse leukemia
Category: Cancer cell line
Comments: Characteristics: Used for the initial screening of antitumor agents. Its sensitivity to the majority of clinically useful antitumor drugs makes it a potentially suitable model for detailed studies of the mechanisms of action of these drugs (PubMed=6850600)., Part of: ENCODE project mouse cell lines.
Proper citation: BCRC Cat# 60049, RRID:CVCL_0382 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_6665
Organism: Mus musculus (Mouse)
Disease: Mouse thymic lymphoma
Category: Cancer cell line
Comments: Biotechnology: Used for mutation assays to predict the carcinogenic potential of chemicals. Allows the quantitation of forward mutations at the thymidine kinase (TK) locus. These TK heterozygous cells are treated with a range of doses of the test substance. The cells are incubated, washed free of tests substance and allowed time for the phenotypic expression of newly induced mutations (PubMed=1093012; PubMed=3416837; PubMed=4360720; PubMed=7329431).
Proper citation: BCRC Cat# 60112, RRID:CVCL_6665 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0421
Organism: Bos taurus (Bovine)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Not susceptible to infection by wild-type and vaccinal strains of myxoma virus (MYXV) (PubMed=17900332)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: BCRC Cat# 60126, RRID:CVCL_0421 Copy
https://web.expasy.org/cellosaurus/CVCL_0360
Organism: Homo sapiens (Human)
Disease: Gestational choriocarcinoma
Category: Cancer cell line
Comments: Caution: Established from the trophoblastic tumor of the placenta of a 24 year old woman, but the cell line is from the male fetus., Karyotypic information: Near triploid karyotype (PubMed=33096371)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: BCRC Cat# 60491, RRID:CVCL_0360 Copy
https://web.expasy.org/cellosaurus/CVCL_3064
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: BCRC Cat# 60231, RRID:CVCL_3064 Copy
https://web.expasy.org/cellosaurus/CVCL_3066
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: BCRC Cat# 60482, RRID:CVCL_3066 Copy
Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_0462
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments: Miscellaneous: PubMed=23430347 has a different value for STR 6-4 (16) than that of NIST (17,18) due to a change in the marker motif (personal communication of Almeida, Jamie L.)., Anecdotal: First established continuous cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Space-flown cell line (cellonaut).
Proper citation: BCRC Cat# 60091, RRID:CVCL_0462 Copy
https://web.expasy.org/cellosaurus/CVCL_W812
Organism: Homo sapiens (Human)
Disease: Uterine carcinosarcoma
Category: Cancer cell line
Comments: Population: Chinese.
Proper citation: BCRC Cat# 60598, RRID:CVCL_W812 Copy
https://web.expasy.org/cellosaurus/CVCL_3548
Organism: Mus musculus (Mouse)
Disease: Mouse medullary thyroid carcinoma
Category: Cancer cell line
Comments:
Proper citation: BCRC Cat# 60413, RRID:CVCL_3548 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0593
Organism: Neovison vison (American mink)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Susceptible to infection by SARS coronavirus (SARS-CoV) (PubMed=15731278)., Virology: Susceptible to infection and replication of influenza A and B viruses (PubMed=9817906)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: BCRC Cat# 60321, RRID:CVCL_0593 Copy
Contaminated Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_1907
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to originate from embryonic intestinal cells (jejunum/ileum)..
Proper citation: BCRC Cat# 60022, RRID:CVCL_1907 Copy
https://web.expasy.org/cellosaurus/CVCL_2580
Organism: Gallus gallus (Chicken)
Disease: Chicken hepatoma
Category: Cancer cell line
Comments: Virology: Efficiently supports the replication of avian leukosis virus subgroup J (ALV-J) (PubMed=29720272)., Virology: Efficient cell line for duck hepatitis B virus (DHBV) DNA synthesis following transfection with viral constructs (PubMed=2352324)., Group: Bird cell line.
Proper citation: BCRC Cat# 60320, RRID:CVCL_2580 Copy
https://web.expasy.org/cellosaurus/CVCL_6418
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Group: Patented cell line.
Proper citation: BCRC Cat# 60409, RRID:CVCL_6418 Copy
Misidentified
https://web.expasy.org/cellosaurus/CVCL_3742
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Problematic cell line: Misidentified. Originally thought to be of human origin but found to be a mouse NCTC clone 929 derivative (PubMed=6451928; PubMed=20143388). Were thought to originate from the synovial fluid in the knee joint of a patient suffering from degenerative arthritis..
Proper citation: BCRC Cat# 60064, RRID:CVCL_3742 Copy
https://web.expasy.org/cellosaurus/CVCL_9125
Organism: Mus terricolor (Earth-colored mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: BCRC Cat# 60203, RRID:CVCL_9125 Copy
https://web.expasy.org/cellosaurus/CVCL_5794
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: BCRC Cat# 60228, RRID:CVCL_5794 Copy
https://web.expasy.org/cellosaurus/CVCL_4350
Organism: Mus musculus (Mouse)
Disease:
Category: Transformed cell line
Comments:
Proper citation: BCRC Cat# 60090, RRID:CVCL_4350 Copy
https://web.expasy.org/cellosaurus/CVCL_3009
Organism: Macaca mulatta (Rhesus macaque)
Disease:
Category: Spontaneously immortalized cell line
Comments: Donor information: Derived from the trypsinization of a pool of kidneys from 6 adult rhesus monkeys., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV) (PubMed=16494729)., Group: Patented cell line., Group: Non-human primate cell line.
Proper citation: BCRC Cat# 60092, RRID:CVCL_3009 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3730
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Senescence: Senesces at ~10 PDL (ATCC=CRL-1762)., Population: African American.
Proper citation: BCRC Cat# 60345, RRID:CVCL_3730 Copy
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