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Proper Citation: RRID:MGI:3850080
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased leukocyte cell number, increased susceptibility to type IV hypersensitivity reaction, postnatal growth retardation, slow postnatal weight gain, chronic inflammation, abnormal macrophage physiology, abnormal lymph node morphology, abnormal dendritic cell physiology, abnormal spleen red pulp morphology, abnormal bone marrow cell physiology, abnormal CD4-positive, alpha beta T cell number, decreased survivor rate, dermatitis, enlarged liver, enlarged lymph nodes, enlarged spleen, increased T-helper 1 cell number, increased activated T cell number, increased anti-double stranded DNA antibody level, increased interleukin-1 beta secretion, increased interleukin-17 secretion, increased interleukin-18 secretion, reduced fertility
Affected Gene: Nlrp3
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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