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Proper Citation: RRID:MGI:3847256
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal spleen periarteriolar lymphoid sheath morphology, increased marginal zone B cell number, increased mature B cell number, increased spleen germinal center size, abnormal Peyer's patch follicle morphology, abnormal immunoglobulin level, increased transitional stage B cell number, increased spleen white pulp amount, abnormal lymph node primary follicle morphology, abnormal spleen morphology, enlarged spleen, increased B cell proliferation, increased B cell number, renal glomerular immunoglobulin deposits, abnormal spleen periarteriolar lymphoid sheath morphology, increased B cell number, increased anti-double stranded DNA antibody level, increased anti-nuclear antigen antibody level, kidney inflammation, increased follicular B cell number, abnormal lymph node primary follicle morphology, increased IgG1 level, enlarged lymph nodes, abnormal spleen primary B follicle morphology, enlarged lymph nodes, enlarged spleen, liver inflammation, premature death, increased urine protein level, glomerulonephritis, increased leukemia incidence, glomerular crescent, glomerulosclerosis, mesangial cell hyperplasia, renal glomerulus fibrosis
Affected Gene: Tnfrsf13b
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI