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URL: https://www.infrafrontier.eu/emma/strain-details/?q=2221
Proper Citation: RRID:IMSR_EM:02221
Description:
Mus musculus with name B6.Cg-B2mtm1Unc Cd4
Species: Mus musculus
Synonyms:
B6.Cg-B2m
Notes: gene symbol note: transgene insertion 1; Beatrice Perarnau|CD4 antigen|transgene insertion 1; Yu Chun Lone|beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1|transgene insertion 2362; Dan R Littman; mutant strain: Tg(HLA-A/H2-D/B2M)1Bpe|Cd4|Tg(H2-Ab1-HLA-DPB1)1Lone|B2m|H2-Ab1|Tg(Cd4-CD4)2362Litt|Tg(H2-Aa-HLA-DPA1)1Lone
Affected Gene: transgene insertion 1; Beatrice Perarnau|CD4 antigen|transgene insertion 1; Yu Chun Lone|beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1|transgene insertion 2362; Dan R Littman
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Issue
Warning. Researchers have noted that this genotype does not sufficiently model human type 1 diabetes mellitus.
Source: Integrated Animals
Source Database: European Mouse Mutant Archive
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant 2U24DK097771-09.
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