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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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Interagency Modeling and Analysis Group Resource Report Resource Website |
Interagency Modeling and Analysis Group (RRID:SCR_007432) | group | The purpose of IMAG is to bring together program officers who have a shared interest in applying modeling and analysis methods to biomedical systems. The meetings are formatted to facilitate an open discussion of what is currently being supported, and for planning future directions in these areas. At each meeting, time is allotted to hear focused presentations from one or two participants to discuss issues relating to modeling and analysis across the government agencies. Discussions also occur online, and participants are informed of talks, conferences and other activities of interest to the group. The NIH BISTIC, (Biomedical Information Science and Technology Consortium), is very supportive of IMAG and serves as the larger body at NIH for disseminating IMAG activities. Associated agencies: NIH: Center for Scientific Review, National Cancer Institute, National Center for Research Resources, National Heart, Lung and Blood Institute, National Human Genome Research Institute, National Institute on Aging, National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Biomedical Imaging and Bioengineering, National Institute of Child Health and Human Development, National Institute on Deafness and Other Communication Disorders, National Institute on Drug Abuse, National Institute of Environmental Health Sciences, National Institute of General Medical Sciences, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Library of Medicine NSF (National Science Foundation): Directorate for Biological Sciences, Directorate for Computer and Information Science and Engineering, Directorate for Engineering, Directorate for Mathematical and Physical Sciences NASA (National Aeronautics and Space Administration): Human Research Program DOE (Department of Energy), Office of Advanced Scientific Computing Research, Office of Biological and Environmental Research DOD (Department of Defense): Air Force Office of Scientific Research (AFOSR), Army, Defense Advanced Research Projects Agency, Office of Naval Research, Telemedicine and Advanced Technology Research Center, USDA (United States Department of Agriculture), USDVA (Unites States Department of Veteran Affairs) Soliciting programs: Predictive Multiscale Models of the Physiome in Health and Disease (MSM Physiome) Initiative; and Multi-Scale Modeling (MSM) InitiativeKey words: MRI, Imaging, human. | national institutes of health, modeling, funding |
is listed by: 3DVC has parent organization: National Institute of Biomedical Imaging and Bioengineering |
Aging | nif-0000-00562 | SCR_007432 | IMAG | 2026-02-14 02:01:26 | 0 | ||||||||
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Institute of Aging - CIHR Resource Report Resource Website 100+ mentions |
Institute of Aging - CIHR (RRID:SCR_007405) | institution | IA (CHIR, Canada) supports research that promotes healthy aging and addresses causes, prevention, screening, diagnosis, treatment, support systems, and palliation for a wide range of conditions associated with aging. :funding resource, grants : |
has parent organization: Canadian Institutes of Health Research is parent organization of: Canadian Consortium on Neurodegeneration in Aging |
Aging | GRID: grid.459197.7; ISNI: 0000 0001 2220 3034; Crossref Funder ID: 501100000026;, nif-0000-00470 | https://ror.org/044mbfr67 http://www.cihr-irsc.gc.ca/e/8602.html |
SCR_007405 | IA | 2026-02-14 02:01:32 | 271 | ||||||||
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Central Brain Tumor Registry of the United States Resource Report Resource Website 10+ mentions |
Central Brain Tumor Registry of the United States (RRID:SCR_008748) | CBTRUS | nonprofit organization | Voluntary, non-profit organization dedicated to collecting and disseminating statistical data. Resource for gathering and disseminating epidemiologic data on all primary benign and malignant brain and other CNS tumors. | human, brain, tumor, cancer, central nervous system, epidemiology, incidence, survival, diagnosis, treatment, benign, malignant, registry, epidemiological data, aggregator, clinical, statistics, population, histology, age, gender, race, hispanic, mortality | Brain tumor, Aging | American Brain Tumor Association ; National Brain Tumor Society ; Pediatric Brain Tumor Foundation ; NCI contract HHSN261201000576P |
PMID:23095881 | Application required., The community can contribute to this resource | grid.492337.8, ISNI: 0000 0004 0484 2205, nlx_143889 | https://ror.org/03849s113 | SCR_008748 | 2026-02-14 02:01:46 | 26 | |||||
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Life Extension Foundation Resource Report Resource Website |
Life Extension Foundation (RRID:SCR_010574) | institution | Established in 1980, the Life Extension Foundation is a nonprofit organization, whose long-range goal is to radically extend the healthy human lifespan by discovering scientific methods to control aging and eradicate disease. The largest organization of its kind in the world, the Life Extension Foundation has always been at the forefront of discovering new scientific breakthroughs for use in developing novel disease prevention and treatment protocols to improve the quality and length of human life. Through its private funding of research programs aimed at identifying and developing new therapies to slow and even reverse the aging process, the Life Extension Foundation seeks to reduce, and ultimately eliminate, such age-related killers as heart disease, stroke, cancer and Alzheimer''s disease. Long-time members are keenly aware of the scientific research that Life Extension Foundation funds to develop validated methods to slow and reverse the aging process. Less known is Life Extension''s multi-prong program to develop safer and more effective cancer therapies. One reason we focus so heavily on cancer research is that this dreaded disease represents a roadblock in our ability to develop effective means to combat aging. | is parent organization of: Life Extension | Aging | ISNI: 0000 0001 0300 2958, nlx_41735, grid.490868.b | https://ror.org/02vzd2x77 | SCR_010574 | 2026-02-14 02:02:01 | 0 | |||||||||
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Aging Intervention Foundation Resource Report Resource Website |
Aging Intervention Foundation (RRID:SCR_008288) | funding resource | A 501(c)(3) non-profit organization that gives out grants created to develop new therapies to control and reverse the causes of aging, as well as treat and prevent the diseases of aging. The goal is to eventually control the processes of aging, reverse their effects, and stay younger longer and ultimately create indefinite youthful, happy and productive lifespan using innovative scientific methods that are under development today in biotech companies and research labs around the world. The foundation also offers education on what we can do now to stay younger, live longer and be happier while new therapies are being developed. | Aging | nif-0000-24032 | SCR_008288 | AIF | 2026-02-14 02:01:39 | 0 | ||||||||||
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American Federation for Aging Research Resource Report Resource Website 1+ mentions |
American Federation for Aging Research (RRID:SCR_000806) | AFAR | non profit organization | A non-profit organization that supports the advance of healthy aging through biomedical research. | funding resource, healthy aging, late adult human, biotechnology | Aging | Crossref funder ID: 100005366, Wikidata: Q4743745, nlx_144115, grid.427612.4, ISNI: 0000 0001 0395 8845 | https://ror.org/000r61a05 | SCR_000806 | 2026-02-14 01:59:49 | 5 | ||||||||
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National Institute on Aging Resource Report Resource Website 100+ mentions |
National Institute on Aging (RRID:SCR_011438) | NIA | institution | National institute that leads the federal government in conducting and supporting research on aging and the health and well-being of older people. The Institute seeks to understand the nature of aging and the aging process, and diseases and conditions associated with growing older, in order to extend the healthy, active years of life. In 1974, Congress granted authority to form NIA to provide leadership in aging research, training, health information dissemination, and other programs relevant to aging and older people. Subsequent amendments to this legislation designated NIA as the primary Federal agency on Alzheimer's disease research. Mission The Institute's mission is to: * Support and conduct genetic, biological, clinical, behavioral, social, and economic research on aging. * Foster the development of research and clinician scientists in aging. * Provide research resources. * Disseminate information about aging and advances in research to the public, health care professionals, and the scientific community,among a variety of audiences. Programs NIA sponsors research on aging through extramural and intramural programs. The extramural program funds research and training at universities, hospitals, medical centers, and other public and private organizations nationwide. The intramural program conducts basic and clinical research in Baltimore, MD, and on the NIH campus in Bethesda, MD. |
is related to: Alzheimers Disease Genetics Consortium is related to: International Genomics of Alzheimers Project has parent organization: NIH Blueprint for Neuroscience Research has parent organization: National Institutes of Health is parent organization of: IADRP is parent organization of: CADRO is parent organization of: Interventions Testing Program is parent organization of: NIA Scientific Resources is parent organization of: Dynamics of Health Aging and Body Composition (Health ABC) is parent organization of: NIA Array Analysis is parent organization of: Intramural Research Program is parent organization of: Alzheimer's Disease Education and Referral Center is parent organization of: Inside NIA: A Blog for Researchers is parent organization of: Genetic Association Database |
Aging, Alzheimer's disease | Wikidata: Q5969362, nlx_inv_1005112, grid.419475.a, Crossref funder ID: 100000049, ISNI: 0000 0000 9372 4913 | https://ror.org/049v75w11 | SCR_011438 | 2026-02-14 02:02:11 | 162 | ||||||||
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Leibniz Institute for Age Research Resource Report Resource Website 1+ mentions |
Leibniz Institute for Age Research (RRID:SCR_011340) | institution | Institute whose mission is to understand the molecular mechanisms that underlie the aging process and that lead to age-related diseases. They hope that eventually this knowledge can contribute to a more healthy aging of people. The central question they are aiming at answering is, What are the molecular mechanisms and genetic factors contributing to the evolution of cellular and organismal dysfunction during human aging? |
has parent organization: Fritz Lipmann Institute; Jena; Germany is parent organization of: Dinucleotide Property Database |
Aging, Age-related disease | nif-0000-30559 | SCR_011340 | Leibniz Institute for Age Research - Fritz Lipmann Institute | 2026-02-14 02:02:17 | 3 | |||||||||
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Dinucleotide Property Database Resource Report Resource Website 1+ mentions |
Dinucleotide Property Database (RRID:SCR_007128) | data or information resource, database | The Dinucleotide Property Database is designed to collect and analyse thermodynamic, structural and other dinucleotide properties. The table presenting all the dinucleotide properties can be pruned and rearranged by different criteria. The database contains different export and analysis functions. | dinucleotide |
is related to: DiProGB has parent organization: Leibniz Institute for Age Research |
Aging | nif-0000-02753 | SCR_007128 | DiProDB | 2026-02-14 02:06:02 | 7 | ||||||||
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Open Access Series of Imaging Studies Resource Report Resource Website 100+ mentions |
Open Access Series of Imaging Studies (RRID:SCR_007385) | OASIS | data or information resource, database | Project aimed at making neuroimaging data sets of brain freely available to scientific community. By compiling and freely distributing neuroimaging data sets, future discoveries in basic and clinical neuroscience are facilitated. | early, stage, alzheimer, disease, mri, fmri, image, brain, dicom, magnetic, resonance, collection, data, FASEB list |
is used by: NIF Data Federation is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) is related to: Automatic Registration Toolbox is related to: 2012 MICCAI Multi-Atlas Labeling Challenge Data has parent organization: Howard Hughes Medical Institute has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA has parent organization: Biomedical Informatics Research Network is parent organization of: Cover Pages |
Alzheimer's disease, Dementia, Normal, Nondemented, Aging | NIA P50 AG05681; NIA P01 AG03991; NIA R01 AG021910; NIMH P50 MH071616; NCRR U24 RR021382; NIMH R01 MH56584 |
Free, Acknowledgement required | r3d100012182, nif-0000-00387 | http://www.nitrc.org/projects/oasis https://doi.org/10.17616/R3RS8K |
SCR_007385 | The Open Access Series of Imaging Studies, Open Access Series of Imaging Studies, OASIS | 2026-02-14 02:06:36 | 299 | ||||
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Odor Molecules DataBase Resource Report Resource Website 1+ mentions |
Odor Molecules DataBase (RRID:SCR_007286) | OdorDB | data or information resource, database | OdorDb is a database of odorant molecules, which can be searched in a few different ways. One can see odorant molecules in the OdorDB, and the olfactory receptors in ORDB that they experimentally shown to bind. You can search for odorant molecules based on their attributes or identities: Molecular Formula, Chemical Abstracts Service (CAS) Number and Chemical Class. Functional studies of olfactory receptors involve their interactions with odor molecules. OdorDB contains a list of odors that have been identified as binding to olfactory receptors. | genetics, cellular, molecular, olfactory, receptor, training material |
is related to: Olfactory Receptor DataBase has parent organization: Yale University; Connecticut; USA works with: ORModelDB |
Aging | Human Brain Project ; NIMH ; NIA ; NICD ; NINDS ; Multidisciplinary University Research Initiative ; NIDCD RO1 DC 009977 |
nif-0000-00056 | SCR_007286 | 2026-02-14 02:06:03 | 1 | |||||||
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Lifespan Observations Database Resource Report Resource Website 1+ mentions |
Lifespan Observations Database (RRID:SCR_001609) | Lifespan Observations Database | data or information resource, database | Database that collects published lifespan data across multiple species. The entire database is available for download in various formats including XML, YAML and CSV. | lifespan, phenotype, intervention, gene, compound, publication |
is used by: NIF Data Federation is used by: Aging Portal is related to: MONARCH Initiative has parent organization: Sageweb |
Aging | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_153873 | http://sageweb.org/lifespandb | SCR_001609 | Sageweb Lifespan Observation Database | 2026-02-14 02:06:05 | 1 | |||||
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Layton Center Clinical Data Resources Resource Report Resource Website |
Layton Center Clinical Data Resources (RRID:SCR_008822) | data or information resource, database | A database housing longitudinal relational research data from over 4,000 research subjects. The database includes the following types of data: physical and neurological exam findings, neurocognitive test scores, personal and family history of dementia, personal demographic genotypes (APOE, HLA), age at service evaluations, age at onset, age at death, clinical diagnosis, neuropathology diagnosis, tissue inventory information (when available), health status, medications, laboratory tests, and MRI data. | clinical data, alzheimer's disease, dementia, genotype, late adult human, longitudinal, clinical, mri |
is related to: Oregon Brain Bank has parent organization: OHSU Layton Aging and Alzheimer's Disease Center |
Aging, Alzheimer's disease | Researchers must submit a request | nlx_144446 | SCR_008822 | Layton Aging and Alzheimer's Disease Center Clinical Data Resources | 2026-02-14 02:06:36 | 0 | |||||||
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Kannisto-Thatcher Database on Old Age Mortality Resource Report Resource Website 1+ mentions |
Kannisto-Thatcher Database on Old Age Mortality (RRID:SCR_008936) | K-T database | data or information resource, database | A database that includes data on death counts and population counts classified by sex, age, year of birth, and calendar year for more than 30 countries. This database was established for estimating the death rates at the highest ages (above age 80). The core set of data in the database was assembled, tested for quality, and converted into cohort mortality histories by V��in�� Kannisto, the former United Nations advisor on demographic and social statistics. Comparable materials on England and Wales, was made available by A. Roger Thatcher, the former Director of the Office of Population Censuses and Surveys and Registrar-General of England and Wales (Kannisto, 1994). The Kannisto-Thatcher database was computerized under the supervision of James W. Vaupel at the Aging Research Unit of the Centre for Health and Social Policy at Odense University Medical School in 1993. Currently, the database is maintained by the Max Planck Institute for Demographic Research, Germany. | mortality, death, population, late adult human, international | has parent organization: Max Planck Institute for Demographic Research; Mecklenburg-Vorpommern; Germany | Aging, Death | Danish Research Councils ; NIA |
Public; must register and agree to terms. For scientific purposes only. | nlx_151834 | SCR_008936 | Kannisto-Thatcher Database on Old Age Mortality at the Max Planck Institute for Demographic Research | 2026-02-14 02:06:10 | 1 | |||||
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Census Microdata Samples Project Resource Report Resource Website |
Census Microdata Samples Project (RRID:SCR_008902) | Census Microdata Samples Project | data or information resource, database | A data set of cross-nationally comparable microdata samples for 15 Economic Commission for Europe (ECE) countries (Bulgaria, Canada, Czech Republic, Estonia, Finland, Hungary, Italy, Latvia, Lithuania, Romania, Russia, Switzerland, Turkey, UK, USA) based on the 1990 national population and housing censuses in countries of Europe and North America to study the social and economic conditions of older persons. These samples have been designed to allow research on a wide range of issues related to aging, as well as on other social phenomena. A common set of nomenclatures and classifications, derived on the basis of a study of census data comparability in Europe and North America, was adopted as a standard for recoding. This series was formerly called Dynamics of Population Aging in ECE Countries. The recommendations regarding the design and size of the samples drawn from the 1990 round of censuses envisaged: (1) drawing individual-based samples of about one million persons; (2) progressive oversampling with age in order to ensure sufficient representation of various categories of older people; and (3) retaining information on all persons co-residing in the sampled individual''''s dwelling unit. Estonia, Latvia and Lithuania provided the entire population over age 50, while Finland sampled it with progressive over-sampling. Canada, Italy, Russia, Turkey, UK, and the US provided samples that had not been drawn specially for this project, and cover the entire population without over-sampling. Given its wide user base, the US 1990 PUMS was not recoded. Instead, PAU offers mapping modules, which recode the PUMS variables into the project''''s classifications, nomenclatures, and coding schemes. Because of the high sampling density, these data cover various small groups of older people; contain as much geographic detail as possible under each country''''s confidentiality requirements; include more extensive information on housing conditions than many other data sources; and provide information for a number of countries whose data were not accessible until recently. Data Availability: Eight of the fifteen participating countries have signed the standard data release agreement making their data available through NACDA/ICPSR (see links below). Hungary and Switzerland require a clearance to be obtained from their national statistical offices for the use of microdata, however the documents signed between the PAU and these countries include clauses stipulating that, in general, all scholars interested in social research will be granted access. Russia requested that certain provisions for archiving the microdata samples be removed from its data release arrangement. The PAU has an agreement with several British scholars to facilitate access to the 1991 UK data through collaborative arrangements. Statistics Canada and the Italian Institute of statistics (ISTAT) provide access to data from Canada and Italy, respectively. * Dates of Study: 1989-1992 * Study Features: International, Minority Oversamples * Sample Size: Approx. 1 million/country Links: * Bulgaria (1992), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/02200 * Czech Republic (1991), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06857 * Estonia (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06780 * Finland (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06797 * Romania (1992), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06900 * Latvia (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/02572 * Lithuania (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/03952 * Turkey (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/03292 * U.S. (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06219 | housing condition, international, minority, population, census, census data, social, economic, middle adult human, late adult human, social science, behavioral science, housing census, social condition, economic condition |
is listed by: Inter-university Consortium for Political and Social Research (ICPSR) is related to: National Archive of Computerized Data on Aging (NACDA) |
Aging, Social phenomena | United Nations Population Fund ; NIA ; United Nations Economic Commission for Europe |
Variable | nlx_151430 | SCR_008902 | Status of Older Persons in UNECE Countries, Dynamics of Population Aging in ECE Countries, PAU Census Microdata Samples Project, Population Activities Unit Census Microdata Samples Project, Dynamics of Population Aging in Economic Commission for Europe Countries | 2026-02-14 02:06:15 | 0 | |||||
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NetAge Database Resource Report Resource Website 1+ mentions |
NetAge Database (RRID:SCR_010224) | NetAge | data or information resource, database | Database that contains gene sets and microRNA-regulated protein-protein interaction networks for longevity, age-related diseases and aging-associated processes. | longevity, protein-protein interaction, mirna-regulated protein-protein interaction network, gene, protein, mirna, biogerontology | has parent organization: Ben-Gurion University of the Negev; Beer-Sheva; Israel | Age-related disease, Aging | PMID:20186480 | Acknowledgement requested, Public | nlx_156769 | SCR_010224 | 2026-02-14 02:06:44 | 6 | ||||||
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Vaccine damage reports database Resource Report Resource Website |
Vaccine damage reports database (RRID:SCR_010740) | Vaccine damage reports database | data or information resource, database | Database of case reports of adverse reactions to vaccinations. There are 806 reports (May 2013). If you would like to report a case, please go to report your own vaccine reaction. The user may search by keywords or sort by vaccine, country, age, outcome, gender and hospital admission. | vaccine, adverse reaction, clinical, male, female, child, adult | Adverse reaction to vaccine, Aging | The community can contribute to this resource | nlx_97470 | SCR_010740 | Vaccine damages database, Adverse reaction/vaccine damage database | 2026-02-14 02:06:39 | 0 | |||||||
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Neuroimage Analysis Center Resource Report Resource Website 1+ mentions |
Neuroimage Analysis Center (RRID:SCR_008998) | NAC | biomedical technology research center, training resource | Biomedical Technology Resource Center that develops image processing and analysis techniques for basic and clinical neurosciences. The NAC research approach emphasizes both specific core technologies and collaborative application projects. The core activity of the center is the development of algorithms and techniques for postprocessing of imaging data. New segmentation techniques aid identification of brain structures and disease. Registration methods are used for relating image data to specific patient anatomy or one set of images to another. Visualization tools allow the display of complex anatomical and quantitative information. High-performance computing hardware and associated software techniques further accelerate algorithms and methods. Digital anatomy atlases are developed for the support of both interactive and algorithmic computational tools. Although the emphasis of the NAC is on the dissemination of concepts and techniques, specific elements of the core software technologies have been made available to outside researchers or the community at large. The NAC's core technologies serve the following major collaborative projects: Alzheimer's disease and the aging brain, morphometric measures in schizophrenia and schizotypal disorder, quantitative analysis of multiple sclerosis, and interactive image-based planning and guidance in neurosurgery. One or more NAC researchers have been designated as responsible for each of the core technologies and the collaborative projects. | brain, neuroimaging, image processing, image analysis, postprocessing, segmentation, registration, algorithm, technique, brain structure, visualization, neurosurgery | has parent organization: Harvard Medical School; Massachusetts; USA | Alzheimer's disease, Aging, Schizophrenia, Schizotypal disorder, Multiple Sclerosis, Neurosurgery | NIBIB P41 EB015902; NCRR P41 RR13218 |
nlx_152643 | SCR_008998 | Neuroimaging Analysis Center | 2026-02-14 02:07:24 | 8 | ||||||
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Program to Reduce Incontinence by Diet and Exercise Resource Report Resource Website 5000+ mentions |
Program to Reduce Incontinence by Diet and Exercise (RRID:SCR_009018) | PRIDE | clinical trial, resource | Randomized controlled trial being conducted at two clinical centers in the United States to learn more about the effects of weight loss on urinary incontinence. About 330 overweight women aged 30 or older will participate and will be followed for 18 months. Efficacy of weight reduction as a treatment for urinary incontinence will be examined at 6 months following the intensive weight control program, and the sustained impact of the intervention will be examined at 18 months. To increase the maintenance of weight reduction and facilitate evaluation of the enduring impact of weight loss on urinary incontinence, they propose to study a motivation-based weight maintenance program. At the end of the intensive weight control program, women randomized to the weight loss program will be randomized to either a 12-month skill-based maintenance intervention or to a motivation-based maintenance intervention. The maintenance interventions maximize the potential for sustained weight loss and will allow them to determine if long-term weight reduction will produce continued improvement in urinary incontinence. | female, adult human, weight reduction, intervention, behavior, diet, exercise, motivation, weight maintenance |
is listed by: ClinicalTrials.gov is related to: NIDDK Information Network (dkNET) has parent organization: University of California at San Francisco; California; USA |
Urinary incontinence, Obesity, Weight loss, Overweight, Aging | NIDDK UO1 DK67860 | PMID:20664387 PMID:20680012 PMID:19179316 PMID:20643425 |
nlx_152847 | SCR_009018 | PRIDE (Program to Reduce Incontinence by Diet and Exercise) | 2026-02-14 02:08:00 | 6544 | |||||
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ACCORD Resource Report Resource Website 100+ mentions |
ACCORD (RRID:SCR_009015) | ACCORD | clinical trial, resource | Study testing whether strict glucose control lowers the risk of heart disease and stroke in adults with type 2 diabetes. In addition the study is exploring: 1) Whether in the context of good glycemic control the use of different lowering lipid drugs will further improve these outcomes and 2) If strict control of blood pressure will also have additional beneficial effects on reducing cardiovascular disease. The design was a randomized, multicenter, double 2 X 2 factorial trial in 10,251 patients with type 2 diabetes mellitus. It was designed to test the effects on major CVD events of intensive glycemia control, of fibrate treatment to increase HDL-cholesterol and lower triglycerides (in the context of good LDL-C and glycemia control), and of intensive blood pressure control (in the context of good glycemia control), each compared to an appropriate control. All 10,251 participants were in an overarching glycemia trial. In addition, one 2 X 2 trial addressed the lipid question in 5,518 of the participants and the other 2 X 2 trial addressed the blood pressure question in 4,733 of the participants. The glycemia trial was terminated early due to higher mortality in the intensive compared with the standard glycemia treatment strategies. The results were published in June 2008 (N Eng J Med 2008;358:2545-59). Study-delivered treatment for all ACCORD participants was stopped on June 30, 2009, and the participants were assisted as needed in transferring their care to a personal physician. The lipid and blood pressure results (as well as the microvascular outcomes and eye substudy results) were published in 2010. All participants are continuing to be followed in a non-treatment observational study. | middle adult human, late adult human, glycemic control, lowering lipid drug, blood pressure, lipid, clinical |
is related to: NIDDK Information Network (dkNET) has parent organization: National Heart Lung and Blood Institute |
Cardiovascular disease, Stroke, Type 2 diabetes, Diabetes, Aging | NHLBI ; NIDDK ; NEI ; CDC ; NIA |
PMID:23490598 PMID:23253271 PMID:23238658 PMID:22723583 PMID:22646230 |
nlx_152746 | SCR_009015 | Action to Control Cardiovascular Disease Risk in Diabetes | 2026-02-14 02:07:33 | 173 |
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